Amira P Tarigan
Universitas Sumatera Utara

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The Relationship Between Bacterial Pattern with Degree of Airflow Limitation FEV1 in Acute Exacerbation of COPD at Adam Malik General Hospital and Pirngadi Hospital Rianti Tarigan; Amira P Tarigan; Dian Dwi Wahyuni; Putri C Eyanoer
Jurnal Respirologi Indonesia Vol 39, No 3 (2019)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v39i3.66

Abstract

Background: Respiratory tract infections are the leading cause of acute exacerbation of COPD (AECOPD). The aim of this study was to investigate the relationship between bacterial pattern and the degree of airflow limitation (FEV1) in patients with acute exacerbation of COPD at Adam Malik General Hospital and Pirngadi Hospital, also the sensitive antibiotics according to the susceptibility test. Methods: This was a cross sectional study of all patients admitted to Adam Malik and Pirngadi Hospital with AECOPD from September 2015 until September 2016. In all 45 subjects who fulfilled the inclusion criteria, the spirometry was examination undergone to evaluate the degree of severity of COPD according to GOLD 2017. In each sample sputum expectoration, the gram smear was made. Barttlet criteria was used to calculate the amount of epithelial cells and PMN. The sample was then grown on blood agar medium. Bacterial susceptibility test to antibiotics was conducted using VITEC 2 methods. Results: From 45 patients, 30 patients (66,7%) had positive sputum cultures. The most frequently isolated pathogen was Streptococcus pneumonia (26,7%). The most sensitive antibiotic was Amikacin (100%). There were no correlation between the in degree of airflow limitation FEV1 and bacterial sputum culture result. There were no significant differences between gram positive or negative bacteria with the degree of airflow limitation. Conclusion: The incidence of bacterial infection based on positive sputum culture in AECOPD was about 66,7% Streptococcus pneumonia was the most common pathogen and Amikacin was the most sensitive antibiotic. There were no significant correlation between the degree of airflow limitation FEV1 with the positive or negative sputum culture and also with the result of gram staining. (J Respir Indo. 2019; 39(3):204-9)
Effect of Lower Extremity Exercise on The Borg Scale in Chronic Obstructive Pulmonary Disease Ghamal Arif Hanafiah; Amira P Tarigan; Pandiaman Pandia; Putri C Eyanoer
Jurnal Respirologi Indonesia Vol 40, No 4 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v40i4.141

Abstract

COPD patients tend to experience complaints shortness of breath, limb muscle fatigue and distress in an effort in activities that result in a decrease in quality of life and inhibit daily activities. This situation will eventually cause the patients to experience fatigue faster and fall into a deconditioning state. The Borg scale is a way to measure the intensity level of physical activity using a ratio scale size. This study aimed to assess the effect of lower limb endurance training on the Borg Scale of COPD patients. A quasi-experimental study conducted on 20 patients with COPD group C and D which underwent lower extremity resistance training. The Borg scale was assessed before and after training, with statistical analysis performed by the Mann Whitney-Test. There was an effect on lower extremity resistance training on the Borg Scale of COPD patients in the form of a significant decrease in the Borg Scale value where in the effort parameters. Before training, the Borg Scale score of COPD patients was 9 and 15, decreased to 1 and 13 after training. While tired feet, before training was 5 which decreases to 3 after training and shortness of breath, before training is 7 which decreases to 4 after training. There is a significant improvement in the value of the Borg Scale of COPD patients after undergoing a lower limb endurance training program. There were no significant Borg scale differences between Group C and Group D after undergoing a lower limb endurance training program.
The Association of Working Duration with Lung Function and Chest X-Ray Results in Ceramic Industry Workers of Company X, Mabar Medan Marini Puspita Sari; Amira P Tarigan; Nuryunita Nainggolan; Putri C Eyanoer; Agus Dwi Susanto; Erlangga Samoedro; Caecilia Marliana
Jurnal Respirologi Indonesia Vol 41, No 1 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i1.158

Abstract

Background: Ceramics industry workers are often exposed to silica materials from ceramics. The aim of this study was to determine the association between silica exposure withlung function test and chest x-ray (CXR) results of the workers. Methods: This was an analytical study with cross-sectional design conducted in the Ceramic Industry X in Mabar, Medan City. The dust level in the work station was measured using Personal Dust Sampler. Lung function was measured by spirometry and CXR was evaluated using the ILO interpretations. Results: About 35 male workers were included as subjects, divided into 3 working stations namely precompression section of 11 subjects (31.4%), compression section of 13 subjects (37.1%) and 11 subjects (31.4%) in the sintering section. Dust levels in each work location are 24.8, 29.2, and 6.11 respectively. Of all subjects, 9 (25.7%) had respiratory symptoms, 21 (60%) had restriction in lung function and 8 (22.8%) had abnormal CXR (6 pneumoconiosis and 2 tuberculosis). There were no association between dust levels with lung function and CXR (P>0.05), but there was a significant correlation between duration of work with lung function. The FEV1 and FVC values of subjects working
Effects of Lower Limb Endurance Training on Maximal Oxygen Uptake (VO2 max) in Chronic Obstructive Pulmonary Disease Andika Pradana; Amira P Tarigan; Tari Mediyanti; Erna Mutiara; Pandiaman Pandia
Jurnal Respirologi Indonesia Vol 37, No 4 (2017)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (374.517 KB) | DOI: 10.36497/jri.v37i4.82

Abstract

Background: Patients with COPD exhibit muscle atrophy and dysfunction which lead into decondition state. This will in turn decrease maximal oxygen uptake (VO2 max) in tissues. Considered as the best predictor of cardiorespiratory endurance and survival, VO2max can be attenuated by aerobic training. This study aimed to assess the effects of lower-limb endurance training on VO2 max in COPD patient. Methods: An experimental study was conducted on 20 COPD patients in group C and D in June–July 2017 at USU Hospital. Patients were prescribed lower-limb exercise by stationary cycling with individualized dose, twice a week for 4 weeks, ranging from 5-20 minutes/session. VO2 max measurement was calculated pre-and post-intervention using Nury’s Formula specifically designed for Indonesian (r=0,68; P
PERAN POLIMORFISME GEN MATRIKS METALLOPROTEINASE-9 DENGAN KEJADIAN PENYAKIT PARU OBSTRUKTIF KRONIK Wilson Arthur Zein; Yahwardiah Siregar; Amira P Tarigan
JURNAL KEPERAWATAN DAN FISIOTERAPI (JKF) Vol 3 No 1 (2020): Jurnal Keperawatan dan Fisioterapi (JKF)
Publisher : Fakultas Keperawatan dan Fisioterapi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jkf.v3i1.427

Abstract

Excessive secretion of MMP-9 is one of the cause of COPD is which can cause undesirable lung tissue degradation. Increased expression of MMP-9 is associated with increased gene promoter activity. The purpose of this study was to determine the role of mettaloproteinase-9 matrix gene polymorphisms with COPD events. This was a case-control study. With a total sample of 60 patients consisting of 30 COPD patients and 30 non-COPD patients. Samples were amplified by PCR (Polymerase Chain Reaction) The results of DNA amplification were digested with SphI restriction enzyme to see the allele variant of MMP-9 C-1562T. Visualization of restriction results with 2% agarose gel electrophoresis will show 2 bands on the T allele (188bp, 247bp), 1 band on the C allele (435bp). The results obtained were homozygous CC variants in COPD 20 (66.67%) and non-COPD 21 (70%). Heterozygous variant of CT 10 (33.33%) in COPD and 9 (30%) in non-COPD. TT variant is not found at all. Based on the results obtained by the most CC homozygous variants in COPD (66.67%) and non-COPD (70%) and no association was found between MMP-9 polymorphism and COPD events (p> 0.05). Based on the results of this study, there is no significant relationship that we can conclude.