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All Journal Nexus Kedokteran Komunitas Universa Medicina
Ana Rima
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Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Pengaruh Efek Samping Obat Anti Tuberkulosis terhadap Kepatuhan Berobat Tuberkulosis Paru di BBKPM Surakarta Setiawan, Made Ratna Dewi; Rima, Ana; Prasetyawati, Arsita Eka
Nexus Kedokteran Komunitas Vol 2, No 1 (2013): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.115 KB)

Abstract

Background: Treatment adherence is a important factor for the recovery of patients with pulmonary tuberculosis. Many factors affect treatment adherence of pulmonary TB patients, one of which is a side effect of anti tuberculosis drugs. This study aims to analyze the influence of the side effects of anti tuberculosis drugs to the tuberculosis treatment adherence in BBKPM Surakarta. Method: This study was observational analytic with cross-sectional approach. The study was conducted in June – July 2012 in BBKPM Surakarta. A total of 48 subjects were selected by purposive sampling method and pulmonary TB patients who have been selected based on inclusion and exclusion criteria. Data retrieval is done by looking at the patient’s medical records and questionnaires. Data were analyzed using Chi-Square analysis method, with SPSS 17.00 for Windows. Result: Data were analyzed with Chi-Square test with a significance level of 0,05 and freedom degrees of 1. Obtained p value of 0.044, which means there is influence of the side effects of anti-tuberculosis drugs to the tuberculosis treatment adherence in BBKPM         Surakarta. Conclusion: It is concluded that there is influence of the side effects of anti tuberculosis drugs to the tuberculosis treatment adherence in Surakarta BBKPM. Keywords: Side effects of drugs, treatment adherence
Sensitivity and specificity of cell block method of transthoracic fine needle aspiration in diagnosis of lung cancer Sutanto, Yusup Subagio; Santi, Nur; Wasita, Brian; Rima, Ana; Kurniawan, Hendra
Universa Medicina Vol. 40 No. 2 (2021)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2021.v40.133-140

Abstract

BackgroundLung cancer is still the main cause of cancer deaths. The high lung cancer mortality rate is caused by a diagnosis factor or therapy selection. The cell block cytology technique using fine needle aspiration (FNA) samples can provide immunocytochemical material that plays an important role in the differential diagnosis of lung cancer subtypes and in determining immunotherapy administration. This study aimed to determine the sensitivity and specificity of transthoracic FNA (TTFNA) cell block cytology in comparison with bronchial washing smears and TTFNA smears in diagnosing lung cancer. MethodsThis was a cross-sectional diagnostic study involving 26 subjects. All subjects had undergone bronchial washing and CT scan-guided fine needle aspiration followed by cell block preparation. Both direct FNA smears and cell blocks are useful in the diagnostic work-up of patients. Comparative statistical analysis of TTFNA cell block versus bronchial washing smear and TTFNA smear cytology was carried out using the McNemar test. ResultsLung cancer was found in 15 patients (57.7%) using the TTFNA cell block technique. The sensitivity and specificity of the TTFNA cell block technique were 85.7% and 75%, respectively. There was no difference in the positivity value between TTFNA cell block technique of bronchial wash smear technique, and TTFNA smear on lung cancer diagnosis (p>0.05). ConclusionsTransthoracic fine-needle aspiration in combination with the cell block technique has good sensitivity and specificity. The TTFNA can be used for immunocytochemical examinations in lung cancer diagnosis and therapy. This approach is valuable for providing individualized treatment and prognostic evaluations.
Pengaruh Efek Samping Obat Anti Tuberkulosis terhadap Kepatuhan Berobat Tuberkulosis Paru di BBKPM Surakarta Made Ratna Dewi Setiawan; Ana Rima; Arsita Eka Prasetyawati
Nexus Kedokteran Komunitas Vol 2, No 1 (2013): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.115 KB)

Abstract

Background: Treatment adherence is a important factor for the recovery of patients with pulmonary tuberculosis. Many factors affect treatment adherence of pulmonary TB patients, one of which is a side effect of anti tuberculosis drugs. This study aims to analyze the influence of the side effects of anti tuberculosis drugs to the tuberculosis treatment adherence in BBKPM Surakarta. Method: This study was observational analytic with cross-sectional approach. The study was conducted in June July 2012 in BBKPM Surakarta. A total of 48 subjects were selected by purposive sampling method and pulmonary TB patients who have been selected based on inclusion and exclusion criteria. Data retrieval is done by looking at the patients medical records and questionnaires. Data were analyzed using Chi-Square analysis method, with SPSS 17.00 for Windows. Result: Data were analyzed with Chi-Square test with a significance level of 0,05 and freedom degrees of 1. Obtained p value of 0.044, which means there is influence of the side effects of anti-tuberculosis drugs to the tuberculosis treatment adherence in BBKPM Surakarta. Conclusion: It is concluded that there is influence of the side effects of anti tuberculosis drugs to the tuberculosis treatment adherence in Surakarta BBKPM. Keywords: Side effects of drugs, treatment adherence
Co-Authors Arsita Eka Prasetyawati Brian Wasita Made Ratna Dewi Setiawan Santi, Nur Yundari, Yundari Yusup Subagio Sutanto