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All Journal JOPS (Journal Of Pharmacy and Science) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) JPK: Jurnal Proteksi Kesehatan Jurnal Pengabdian Inovasi dan Teknologi Kepada Masyarakat JFARM (Jurnal Farmasi) Borneo Journal of Pharmacy
Asiska Permata Dewi
Universitas Abdurrab
Arts Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Other

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Journal : Borneo Journal of Pharmacy

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Formulation and Antibacterial Activity of Liquid Soap Containing Ketapang (Terminalia catappa L.) Leaves Extract Asiska Permata Dewi; Dini Mardhiyani
Borneo Journal of Pharmacy Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i1.1589

Abstract

Ketapang (Terminalia catappa L.) is traditionally used by the community to treat the skin's infections caused by bacteria or fungi. In this study, T. catappa leaves extract was added to the liquid soap formula as an antibacterial. The purpose of this study was to determine the secondary metabolite compounds contained in T. catappa leaves extract, physical evaluation of the preparation, and antibacterial activity of liquid soap. Liquid soap formula was made with various concentrations of T. catappa leaves extract F0 (0%), F1 (1%), F2 (2%), and F3 (3%). The resulting soap was evaluated for organoleptic, pH, high foam, homogeneity, irritation, and its activity against Staphylococcus aureus, Staphylococcus epidermidis, and Escherichia coli using the disc diffusion method. The results showed that the T. catappa leaves extract contained flavonoids, tannins, saponins, and triterpenoids. The liquid soap formula F0 was clear, while F1, F2, and F3 had the characteristics of brown-dark brown, homogeneous, pH between 4.6-5.2, foam stability between 67-72%, which was not significantly different and stable after five minutes of testing, and it did not irritate the skin. Terminalia catappa leaves extracts liquid soap has antibacterial activity at a concentration of 1%, 2%, and 3%, with the largest inhibition zone diameter produced by S. aureus.
Co-Authors Ade Febriani Ayu Permata Denia Pratiwi Dini Mardhiyani Henni Rosaini Islami, Deri Isna Wardaniati Konny Putriani Mega Pratiwi Irawan, Mega Pratiwi Nova Relida Samosir Saniya Saniya Sri Kartini Sri Zerita Azlin Wahyu Margi Sidoretno Wahyu Ramadhan Yose Rizal Yulia Yesti