<![CDATA[Background: Cervical cancer is in the second place among the incidence of new cases and in thethird highest death from cancer. Cancer depression and severity generally occur together with psychological problems, such as anxiety, pain and fatigue. Most studies in cancer patients have focused on morbidity or mortality more due to the risk of depression. The purpose of this study was to analyze the factors that influence depression in cervical cancer patients.Subjects and Method: A cross sectional study was conducted at Dr. Moewardi Hospital, Surakarta, Central Java, from September to October 2019. A sample of 200 cervical cancer patients was selected by simple random sampling. The dependent variable was depression. The independent variables were marital status, education, occupation, family income, peer support, family support, health personnel support, coping strategy, cancer stage, frequency of chemotheÂrapy, and length of illness from diagnosis. Depression was measured by the Beck Depression Inventory-II (BDI-II) questionnaire. The other data were collected by medical record and questionÂnaire. The data were analyzed by path analysis run on Stata 13.Results: Severe depression in cervical cancer patients was directly increased by the frequency of chemotherapy 3 times (b= 1.80; 95% CI= 0.11 to 3.49; p= 0.037), advanced stage (b= 2.50; 95% CI= 0.18 to 4.82; p= 0.035), and length of illness from diagnosis ≥11 months (b= 2.27; 95% CI= 0.57 to 3.96; p= 0.009). Severe depression was directly decreased by high coping strategy (b= -6.33; 95% CI= -8.68 to -3.98; p<0.001). Severe depression was indirectly affected by peer support, family support, support of health personnel, family income, occupation, education, and marital status.Conclusion: Severe depression in cervical cancer patients is directly increased by the frequency of chemotherapy 3 times, advanced stage, and length of illness from diagnosis ≥11 months. Severe depression is directly decreased by high coping strategy. Severe depression is indirectly affected by peer support, family support, support of health personnel, family income, occupation, education, and marital status.Keywords: depression, cervical cancer, path analysisCorrespondence: Dewi Shinta. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta, Central Java, Indonesia. Email: shintadw94@gmail.com. Mobile: 08236495Â0175Journal of Epidemiology and Public Health (2019), 4(4): 338-350https://doi.org/10.26911/jepublichealth.2019.04.04.09]]>
