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Bacterial Mapping Toward Patients in Intensive Care Unit Dr. Soebandi Jember Hospital Achmad Ma'ruf Fauzi; Muhammad Ali Shodikin; Yuli Hermansyah
Journal of Agromedicine and Medical Sciences Vol 5 No 3 (2019)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v5i3.6821

Abstract

Intensive Care Unit (ICU) a part of the hospital with specialized staff and equipment specially to the observation, care and treatment of patients suffering from life threatening complications. The importance of knowing the mapping of bacterial is to know the types of bacterial and the resistance of bacterial to the therapy that will be given. The research used is descriptive by taking primary data. Criteria of research sample in the form of blood culture in patients in ICU RSD. Dr. Soebandi Jember. Sampling method is by using total sampling technique. The results is S. xylosus (55.60%), S. epidermidis (11.10%), Enterobacter cloacea (11.10%) and Stenotrophomonas maltophilia (11.105). Sensitivity test results of Staphylococcus xylosus bacteria showed resistant to class III cephalosporin group, Erythromycin, penicillin, clindamycin and macroloid. While the sensitive to chloramphenicol, linezolid, glikopeptida and vancomycin. The results of the antibiotic sensitivity test of Staphylococcus epidermidis, Enterobacter cloacea, and Stenotrophomonas maltophilia are sensitive to tetracycline and aminoglycoside antibiotics. Meanwhile, antibiotic sensitivity test of Staphylococcus epidermidis and Streptococcus sp are resistant to antibiotic penicillins, fourth generation cephalosporin, erythromycin, azithromycin. Streptococcus sp and Stenotrophomonas maltophilia are resistant to ceftriaxone antibiotic.
Risk Factor Analysis of Dengue Shock Syndrome Occuring to Children in RSD dr. Soebandi Jember Regency Oessi Salsabila; Muhammad Ali Shodikin; Dwita Aryadina Rachmawati
Journal of Agromedicine and Medical Sciences Vol 3 No 1 (2017)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v3i1.4099

Abstract

Dengue Shock Syndrome is a medical emergency situation caused by shocking DHF. Some factors that can influence the DSS. The purpose of this research know some risk factors that might cause DSS. Those are age, nutritional status, gender, and amount of platelet and hematocrit. This research was retrospective case control doing in dr. Soebandi Hospital Jember. The sample were divided into 2 groups. Those were DSS (case group) and non-DSS group (control group). Data analysis was done by Chi-Square test using SPSS 21 version. These were 136 patients which were divided into 94 patients of control group and 42 patients of case group. In this research, there were p-value for ages, nutritional status, gender, amount of platelet and hematocrit on each 0,450; 0,490; 0,198; 0,001; 0,007 respectively. In this search, it could be concluded that age, nutritional status, and gender were not significantly related to DSS case although amount of platelet and hematocrit were significantly related to DSS case.Keywords:dengue shock syndrome, age, nutritional status, gender, hematocrit, platelet.
The Difference of Eosinophil Amount in Tuberculosis Patients with and without Soil-Transmitted Helminths Co-infection in Panti District, Jember Yunita Armiyanti; Nisrina Salsabila Firmansyah; Angga Mardro Raharjo; Muhammad Ali Shodikin; Enny Suswati; Dini Agustina
NurseLine Journal Vol 5 No 1 (2020): May 2020
Publisher : Faculty of Nursing, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/nlj.v5i1.16729

Abstract

Tuberculosis is one of the world's health problems even in Indonesia. The immune response that needed to deal with TB can be influenced by other infections, such as helminth infection. The helminth infections induce Th2 immune responses and eosinophilia to eliminate these pathogen. Meanwhile, the Th2 response and eosinophilia can also suppress the Th1 immune response which is very important to eliminate the bacterium M. tuberculosis and make a negative impact on the success of TB therapy. Thus, the eosinophil profile can describe the immune response in TB patients with helminth co-infection. This study aims to determine the prevalence of helminthiasis in TB patients and determine the differences in eosinophil amount in tuberculosis patients with and without helminth co-infection. This study was an observational analytic study with a cross-sectional design conducted at Puskesmas Panti in August 2019-January 2020 using fecal and blood samples from 24 research subjects. Helminth co-infection status was obtained from fecal examination with sedimentation and flotation methods while the number of eosinophils was obtained from leukocyte counts. Data analysis used the Mann Whitney U test to determine differences in the number of eosinophils in the two groups. The results showed there was no difference in the number of eosinophils in TB patients with helminth co-infection and without helminth co-infection (p> 0.05). There is no typical picture of the number of eosinophils in both groups so that eosinophils cannot describe the immune response that arose in TB patients with helminth co-infections in Panti district, Jember.
Hubungan antara Higiene Perorangan dan Kejadian Koinfeksi Cacingan pada Penderita Tuberkulosis Shofia, Lailatis; Hermansyah, Bagus; Suswati, Enny; Agustina, Dini; Mufida, Diana Chusna; Shodikin, Muhammad Ali
Sriwijaya Journal of Medicine Vol. 4 No. 1 (2021): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/SJM.v4i1.153

Abstract

Tuberculosis (TB) and intestinal worms are infectious diseases with a large number of sufferers in Indonesia. The high prevalence of intestinal worms in Indonesia allows the occurrence of STH coinfection in pulmonary TB patients which causes anti M. tuberculosis immunity to decrease so that the response to tuberculosis treatment is not optimal. One of the risk factors of STH infection is personal hygiene. The purpose of this study was to analyze the relationship between individual hygiene and the incidence of STH coinfection in TB patients in Tempurejo Sub-District, Jember District. This type of research is observational research with cross sectional analytic design. The population used was TB patients in Tempurejo Sub-District in the period September - October 2019. The data used in this study were primary data in the form of interviews and results of stool examination. Stool examination is carried out using the sedimentation and floatation methods. Data analysis was performed using Fisher's exact test. The results of this study indicate that the incidence of STH co-infection in TB patients in Tempurejo Subdistrict is 9.67% and is caused by two STH species, A. lumbricoides (66.7%) and Hookworm (33.3%). Respondents' personal hygiene consisted of good hygiene (64.5%) and bad hygiene (35.5%), where 66.7% of cases of STH coinfection occurred in respondents with poor personal hygiene. Fisher's test results showed that there was no significant relationship between personal hygiene with the incidence of STH coinfection in TB patients in Tempurejo Sub-District, Jember District (p-value of 0.281).
Hubungan antara Higiene Perorangan dan Kejadian Koinfeksi Cacingan pada Penderita Tuberkulosis Shofia, Lailatis; Hermansyah, Bagus; Suswati, Enny; Agustina, Dini; Mufida, Diana Chusna; Shodikin, Muhammad Ali
Sriwijaya Journal of Medicine Vol. 4 No. 1 (2021): Sriwijaya Journal of Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/SJM.v4i1.153

Abstract

Tuberculosis (TB) and intestinal worms are infectious diseases with a large number of sufferers in Indonesia. The high prevalence of intestinal worms in Indonesia allows the occurrence of STH coinfection in pulmonary TB patients which causes anti M. tuberculosis immunity to decrease so that the response to tuberculosis treatment is not optimal. One of the risk factors of STH infection is personal hygiene. The purpose of this study was to analyze the relationship between individual hygiene and the incidence of STH coinfection in TB patients in Tempurejo Sub-District, Jember District. This type of research is observational research with cross sectional analytic design. The population used was TB patients in Tempurejo Sub-District in the period September - October 2019. The data used in this study were primary data in the form of interviews and results of stool examination. Stool examination is carried out using the sedimentation and floatation methods. Data analysis was performed using Fisher's exact test. The results of this study indicate that the incidence of STH co-infection in TB patients in Tempurejo Subdistrict is 9.67% and is caused by two STH species, A. lumbricoides (66.7%) and Hookworm (33.3%). Respondents' personal hygiene consisted of good hygiene (64.5%) and bad hygiene (35.5%), where 66.7% of cases of STH coinfection occurred in respondents with poor personal hygiene. Fisher's test results showed that there was no significant relationship between personal hygiene with the incidence of STH coinfection in TB patients in Tempurejo Sub-District, Jember District (p-value of 0.281).
Risk Factors of Perinatal Death Age 0-28 Days at RSD dr. Soebandi Jember Ainindya Pasca Rachmadiani; Muhammad Ali Shodikin; Cicih Komariah
Journal of Agromedicine and Medical Sciences Vol 4 No 2 (2018)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v4i2.6737

Abstract

Abstract Perinatal deaths are babies who die at <28 days of birth. According to WHO, there are 2.7 million perinatal deaths worldwide in 2015. In 2016, the number of infant mortality at Jember is 50.19 per 1000 live births and become the second rank in Jawa Timur after Probolinggo. Infant mortality has been associated by maternal, gestational and neonatal factors. The aim of this study is to determine the risk factors of perinatal death age 0-28 days in RSD dr. Soebandi Kabupaten Jember. This research was analytic observasional with case control design doing in RSD dr. Soebandi Kabupaten Jember. The samples were 65 cases and 65 controls. Data analysis was done by Chi-square test and Fisher’s exact test with significance value < 0,05. The results showed APGAR Score (p <0.001, OR = 6.51), birth weight (p <0.001, OR = 9.66), body length (p <0.001 OR = 5.07), gestational age (p = 0.002; OR = 2.92), congenital anomalies (p = 0.013; OR = -) and maternal age (p = 0.001; OR = 4.51) were risk factors for perinatal death 0-28 days in RSD dr. Soebandi Kabupaten Jember. Keywords: perinatal deaths, neonatal factors, maternal factors, gestational factors.
Risk Factors for Stunting at Balung Health Center, Jember Regency, Indonesia Agustin, Aisyiyah Alviana; Shodikin, Muhammad Ali
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 6, No 2: June 2021
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v6i2.493

Abstract

Stunting is a condition of failure to thrive in children under five years of age as a result of chronic malnutrition so that the child is too short for his age. The prevalence rate of stunting in Indonesia is still above 20%, meaning that it has not reached the target. Factors that influence stunting include birth length and birth weight. The purpose of this study was to determine the description of the factors that influence the incidence of stunting in children aged 0-59 months in the working area of the Balung Public Health Center in 2021. This research is descriptive in nature which was conducted Stunting is a condition of failure to thrive in children under five years of age as a result of chronic malnutrition so that the child is too short for his age. The prevalence rate of stunting in Indonesia is still above 20%, meaning that it has not reached the target. Factors that influence stunting include birth length and birth weight. The purpose of this study was to determine the description of the factors that influence the incidence of stunting in children aged 0-59 months in the working area of the Balung Public Health Center in 2021. This research is descriptive in nature, which was conducted in the working area of Puskesmas Balung, Jember Regency in April 2021. The population is children under five with age stunting. 0-59 months recorded in the EPPGBM in February 2021. Sampling in this study was carried out by total sampling, namely as many as 639 stunting toddlers. Of the 639 stunted children under five, 347 were male and the majority occurred at the age of 12-23 months, namely 150 under five. From 639 toddlers, it describes 516 toddlers with normal body length and 123 toddlers with short birth lengths. Meanwhile, the birth weight of 639 children under five shows that 422 children under five were born with normal birth weight. From the data above, it can be concluded that the majority of children under five with stunting in the working area ofPuskesmas Balung were born with normal body length and weight. For this reason, it is necessary to carry out further research on the relationship of several risk factors using statistical tests. In addition, it is also necessary to look for other risk factors that can cause stunting in children.  Abstrak: Stunting adalah kondisi gagal tumbuh pada anak balita (bayi di bawah lima tahun) akibat dari kekurangan gizi kronis sehingga anak terlalu pendek untuk usianya. Angka prevalensi stunting di Indonesia masih di atas 20%, artinya belum mencapai target. Faktor yang mempengaruhi stunting diantaranya panjang badan lahir dan berat badan lahir. Tujuan penelitian ini adalah untuk mengetahui gambaran faktor yang mempengaruhi kejadian stunting pada balita usia 0-59 bulan di wilayah kerja Puskesmas Balung Tahun 2021. Penelitian ini bersifat deskriptif yang dilakukan di wilayah kerja Puskesmas Balung Kabupaten Jember pada bulan April 2021.  Populasi adalah balita stunting usia 0-59 bulan yang terdata pada EPPGBM pada bulan Februari 2021. Pengambilan sampel pada penelitian ini dilakukan dengan cara total sampling yaitu sebanyak 639 balita stunting. Dari 639 balita stunting, 347 berjenis kelamin laki-laki dan mayoritas terjadi pada usia 12-23 bulan yaitu sebesar 150 balita. Dari 639 balita menggambarkan 516 balita lahir dengan panjang badan normal dan 123 balita memiliki panjang badan lahir pendek. Sedangkan berat badan lahir 639 balita mengambarkan 422 balita lahir dengan berat bdan lahir normal. Dari data diatas dapat disimpulkan bahwa mayoritas balita stunting di wilayah kerja Puskesmas Balung ini lahir dengan kondisi panjang bdan dan berat badan normal. Untuk itu perlu dilakukan penelitian lebih lanjut mengenai hubungan beberapa faktor risiko tersebut dengan menggunakan uji statistik. Selain itu perlu juga dilakukan pencarian faktor risiko lain yang bisa menjadikan stunting pada anak.
The Correlation between HIV/AIDS Positive Pregnant Mother with Infant APGAR Score in RSD dr. Soebandi Jember Nurlaila Ayu Purwaningsih; Muhammad Ali Shodikin; Cholis Abrori
Journal of Agromedicine and Medical Sciences Vol 4 No 3 (2018)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v4i3.6781

Abstract

Human Immunodeficiency Virus (HIV) is a virus that decreased immunity and a set symptoms of diseases called Acquired Immune Deficiency Syndrome (AIDS). One of the major risk factors for HIV transmission is perinatal transmission about 2.8% during pregnancy, delivery, and postpartum. HIV positive mothers have a potential to give birth infants with low APGAR. APGAR Score was used as a reference to determine asphyxia in the first and fifth minutes of life. The purpose of this research were to determine the correlation between HIV/AIDS positive pregnant mother with infant APGAR Score and to determine the other factors that affect the infant APGAR Score in RSD dr. Soebandi Jember. This research used observational analytic survey method with cross sectional design using medical record of HIV positive and negative pregnant women from August 2014-July 2017 in RSD dr. Soebandi Jember as a subject that qualify the inclusion and exclusion criteria. This research used case group sampling technique by total sampling and control group by simple random sampling each 52 samples. Test result of the correlation between HIV/AIDS positive pregnant mother with infant APGAR Score using Chi-Square test obtained p value=1.000 (OR=1.13) that means there was no significant correlation. Test result of the correlation between the other factors that affect infant APGAR Score concluded that there were no significant correlation. Keywords: pregnant mother, HIV/AIDS, APGAR Score, infant
Interleukin-22-induced β‑defensin-2 expression by intranasal immunization with Streptococcus pneumoniae RrgB epitopes Mufida, Diana Chusna; Saputra, Antonius Dwi; Hermansyah, Bagus; Agustina, Dini; Shodikin, Muhammad Ali; Armiyanti, Yunita
Universa Medicina Vol. 41 No. 1 (2022)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2022.v41.37-46

Abstract

BackgroundStreptococcus pneumoniae causes pneumococcal disease, which is responsible for millions of deaths worldwide. Various pneumococcal vaccine candidates have been developed to prevent S. pneumoniae infection, one of which is an epitope-based vaccine. This study aimed to prove that intranasal immunization with each of the five S. pneumoniae RrgB epitopes can induce a mucosal immune response by increasing the β-defensin-2 concentration through upregulation of interleukin (IL)-22 expression. MethodsAn experimental laboratory study was conducted using 28 male Wistar rats aged 3-4 months, that were randomly divided into 7 groups containing four rats each. Group 1 was given 40 mL of phosphate-buffered saline (PBS) only (control group). Group 2 was the adjuvant group that received 40 mL PBS containing 2 ìg cholera toxin B (CTB), and groups 3-7 were immunized with 40 mL PBS containing a combination of adjuvant and one of the five different S. pneumoniae RrgB epitopes. The concentrations of IL-22 and β-defensin-2 from nasal rinse examination were measured by means of ELISA. The Kruskal-Wallis test, followed by the Mann-Whitney post-hoc test were used for statistical analysis. ResultsRats immunized with the adjuvant-epitope combination had significantly higher β-defensin-2 and IL-22 levels than the control group (p=0.030; p=0.018, respectively), according to the Kruskal-Wallis test. And the Mann-Whitney statistical test, showed there was a significant increase in β-defensin-2 and IL-22 levels. ConclusionsIntranasal immunization with epitope 1 of the S. pneumoniae RrgB can increase β-defensin-2 expression significantly and has a greater potential to be developed into a pneumococcal vaccine.
THE RELATION OF PERSONAL HYGIENE WITH THE RISK OF OCCURRENCE OF SOIL-TRANSMITTED HELMINTH CO-INFECTION IN TB PATIENTS IN THE WORKING AREA OF THE JENGGAWAH HEALTH CENTER IN JEMBER REGENCY Ellen Ocktavironita; Bagus Hermansyah; Angga Mardro Raharjo; Diana Chusna Mufida; Dini Agustina; Muhammad Ali Shodikin
Majalah Kedokteran Sriwijaya Vol 52, No 2 (2020): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v52i2.11977

Abstract

Tuberculosis (TB) and soil-transmitted helminth (STH) infections are infectious diseases with a high prevalence in Indonesia. STH co-infection in TB patients can worsen the prognosis of TB disease due to the dysregulation of the immune response. The high prevalence of STH infections in Indonesia is caused by environmental factors such as poor personal hygiene habits. Jenggawah Subdistrict is an area with a high number of TB cases in Jember Regency and most of the area is in the form of agricultural fields and plantations that have a suitable humidity and temperature for the development of STH. The purpose of this study was to determine the relationship of personal hygiene risk factors with the risk of STH co-infection in TB patients in the work area of the Jenggawah Health Center in Jember Regency. This study used an observational analytic design with a cross sectional method and was conducted from September to December 2019. The research was conducted at the TB Polyclinic in Jenggawah Health Center in Jember Regency with a total sample of 26 respondents who were given a personal hygiene questionnaire. Stool examination was conducted at the Laboratory of Parasitology FK UNEJ using sedimentation and flotation methods. The results showed the incidence of STH co-infections was 15.3%, good personal hygiene was 57.7%, and bad personal hygiene was 42.3%. Fisher exact test results showed that there was no significant relationship between personal hygiene risk factors and the risk of the occurrence of STH co-infection in TB patients in the working area of the Jenggawah Health Center in Jember Regency (p = 1,000).