Article Per Year (5 Year)
p-Index From 2019 - 2024
0.562
P-Index
This Author published in this journals
All Journal Medical Journal of Indonesia Paediatrica Indonesiana Majalah Kedokteran Nusantara The Journal Of Medical School Cermin Dunia Kedokteran
Pertin Sianturi
Unknown Affiliation
Health Professions Medicine & Pharmacology Public Health

Published : 10 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 10 Documents
Search

 1 
Incidence of epilepsy among patients with cerebral palsy (CP) in Yayasan Pemeliharaan Anak Cacat (YPAC) – Medan Saing, Bistok; Sianturi, Pertin; Syarifuddin, Amir
Medical Journal of Indonesia Vol 11, No 3 (2002): July-September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (223.429 KB) | DOI: 10.13181/mji.v11i3.69

Abstract

Epilepsy is a chronic condition due to cerebral function disorders. Epilepsy occurs as a common complication of many neurological disorders such as cerebral palsy (CP) that can cause further brain damage if especially they are accompanied with prolonged seizure. The incidence of epilepsy among patients with CP varies, 25-35%. The high incidence of epilepsy among patients with CP suggests that these disorders has common or related origins. We carried out a retrospective study to determine the incidence of epilepsy among patients with CP registered July 1988 to June 1998 in YPAC Medan and to determine whether the incidence of epilepsy was different according to type of CP. Data was compiled from medical records, including name, sex, parity, mothers age, prenatal, perinatal, and postnatal history, and EEG resuts. Data were analysed using statistical computer program and its significance was evaluated by chi square test at p < 0.05. There were 67 cases with CP, 53 cases spastic CP, 13 cases mixed CP and one case dyskinetic CP. Of the 67 cases CP, 47.8% were male, 52.2% female with the mean age of 50.3 (SD 36.9) months. There were 25 (37.3%) patients CP associated with epilepsy, 72% general seizures, 20% partial seizures, and 8% infantile spasm. The incidence of epilepsy was significantly different among patients with CP associated with the type of CP and gestational age, p < 0.05. We concluded that the incidence of epilepsy among patient with CP in YPAC Medan was 37.3% and showed significant difference in CP according to type and gestational age. (Med J Indones 2002; 11: 158-63) Keywords: epilepsy, cerebral palsy, obstetric history, gestational age
Nutrisi Agresif untuk Neonatus Kurang Bulan Febriyanti Marito Lubis, Nikmah; Mardina Lubis, Bugis; Dasa Tjipta, Guslihan; Sianturi, Pertin; Syofiani Hasibuan, Beby; Lubis, Syamsidah; Wahyuni, Fera
Cermin Dunia Kedokteran Vol 46, No 5 (2019): Pediatri
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (486.566 KB) | DOI: 10.55175/cdk.v46i5.484

Abstract

Banyak neonatus kurang bulan yang mengalami gagal tumbuh setelah lahir, salah satunya akibat nutrisi tidak adekuat. Pemberian nutrisi agresif mulai dikembangkan untuk mengatasi hal tersebut dengan pemberian nutrisi secara enteral atau parenteral segera setelah lahir. Praktik tersebut terbukti dapat memperbaiki tumbuh kembang neonatus kurang bulan dengan efek samping tidak signifikan.Many preterm newborns suffer from antenatal growth deprivation, which may be caused by inadequate nutritional intake. Aggressive nutritional support by administering enteral or parenteral nutrition immediately after birth is developed to treat the condition. This practice may improve growth and development of preterm newborns with insignificant adverse events. 
Peran Vitamin D pada Epilepsi Anak Batubara, Ratna Suwita; Saing, Johannes Harlan; Sianturi, Pertin; Dimyati, Yazid; Destariani, Cynthea Prima
Cermin Dunia Kedokteran Vol 46, No 10 (2019): Farmasi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (694.588 KB) | DOI: 10.55175/cdk.v46i10.432

Abstract

Vitamin D memiliki peran penting selama perkembangan otak, proliferasi, diferensiasi, neurotrofik dan neuroprotektif. Bentuk aktif vitamin D menekan inflamasi dan mengubah keseimbangan antara sitokin inhibitor dan sitokin eksitasi. Bentuk aktif vitamin D menunjukkan efek imunomodulator dan secara efektif dapat menekan inflamasi sehingga mempunyai efek antikonvulsan. Penderita epilepsi anak berisiko tinggi defisiensi vitamin D.Pemakaian obat antiepilepsi sebagai politerapi dihubungkan dengan penurunan kadar vitamin D yang lebih besar dibandingkan obat antieepilepsi sebagai monoterapi. Pemberian vitamin D harus cukup untuk mempertahankan kadar normal 25(OH)D (≥30 ng/mL). Pemberian vitamin D pada epilepsi dapat meningkatkan batas ambang kejang secara signifikan dan mengurangi keparahan kejang.Vitamin D has an important role during brain development, proliferation, differentiation, neurotrophic and neuroprotection. The active form of vitamin D suppresses inflammation and changes the balance between inhibitory cytokines and excitatory cytokines. The active form of vitamin D shows an immunomodulatory effect and can effectively suppress inflammation so that it has an anticonvulsant effect. Epileptic children are in high risk of vitamin D deficiency. Antiepileptic polytherapy is associated with a greater reduction in vitamin D levels than in monotherapy. Vitamin D supplementation must be sufficient to maintain normal level of 25(OH)D (≥30 ng/mL. Vitamin D can significantly increase the seizure threshold and reduce the severity of seizure. 
Intoleransi Makanan pada Neonatus Kurang Bulan Handayani Ardy, Nurul; Sianturi, Pertin
Cermin Dunia Kedokteran Vol 45, No 11 (2018): Neurologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (492.433 KB) | DOI: 10.55175/cdk.v45i11.570

Abstract

Intoleransi makanan adalah masalah pencernaan yang paling umum pada bayi prematur saat menyusui. Intoleransi makanan akan menyebabkan kurangnya nutrisi neonatus sehingga mempengaruhi proses pertumbuhan. Mekanisme intoleransi makanan tidak jelas tetapi dapat dipengaruhi oleh beberapa faktor fisiologis seperti pematangan motilitas saluran pencernaan, penundaan pengosongan lambung, saluran pencernaan dan penyerapan yang belum matang. Intoleransi makanan juga berhubungan dengan morbiditas seperti sepsis neonatal dan Necrotizing Enterocolitis (NEC).Food intolerance is the most common digestive problems in preterm infants during breastfeeding. Infant with food intolerance will get less nutrients thus affecting growth. The exact mechanism of food intolerance may be affected by several physiological factors such as maturation of the gastrointestinal tract motility, delayed gastric emptying, gastrointestinal tract and malabsorption. Food intolerance is also associated with morbidity such as neonatal sepsis and necrotizing enterocolitis (NEC)
Analisis Gas Darah dan Laktat Darah Tali Pusat sebagai Parameter Metabolik pada Asfiksia Perinatal Sitanggang, Fitri Parinda; Lubis, Bugis Mardina; Dimyati, Yazid; Tjipta, Guslihan Dasa; Syofiani, Beby; Sianturi, Pertin; Lubis, Syamsidah; Wahyuni, Fera
Cermin Dunia Kedokteran Vol 46, No 9 (2019): Neuropati
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (588.827 KB) | DOI: 10.55175/cdk.v46i9.437

Abstract

Asfiksia masih merupakan salah satu penyebab utama kematian neonatus per tahun. Skor Apgar dapat memberikan informasi vitalitas neonatus namun memiliki beberapa keterbatasan. Asfiksia perinatal dapat muncul dari berbagai risiko intrapartum dan postpartum yang mengakibatkan terhentinya pertukaran gas pada fetus. Metabolisme anaerob akan menyebabkan akumulasi laktat dan penurunan pH. Analisis asam-basa dan laktat darah tali pusat dapat memberikan penilaian objektif terhadap status metabolik neonatus.Asphyxia still remain a major causes of neonatal death per year. Apgar score provides information on neonatal vitality but has several limitations. Perinatal asphyxia can arise from a variety of intrapartum and postpartum risks which result in cessation of gas exchange. Anaerobic metabolism will cause lactate accumulation and pH decrease. Analysis of acid-base and lactate in cord blood can provide an objective assessment of the metabolic status of the neonate. 
Comparison of blood glucose levels in breastfed vs. formula-fed low birth weight infants Eli Tua Pangaribuan; Bugis M. Lubis; Pertin Sianturi; Emil Azlin; Guslihan D. Tjipta
Paediatrica Indonesiana Vol 49 No 1 (2009): January 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (108.771 KB) | DOI: 10.14238/pi49.1.2009.15-9

Abstract

Background  Low  birth weight infants are defined  as  babies withbirth weight less  than  2500 grams.  Low  birth weight infants tendto suffer from hypoglycemia compared to full term infants.  Theincidence  of  hypoglycemia in newborns varies between 1.3 and  3per 1000 live births. Blood glucose levels in formula-fed infantsare lower  than  those in breastfed infants.Objective  To  compare blood glucose levels in breastfed  andformula-fed low birth weight infants.Methods  A cross sectional study was conducted between February2007  and  June 2007  at  Pirngadi and H. Adam Malik GeneralHospital in Medan,  North  Sumatra, Indonesia. All low birthweight babies were classified into two groups: the breastfed  andformula-fed. Each group consisted  of  32 infants. Capillary bloodwas collected using heel pricks  at  1,  48,  and  72 hours after birth,and plasma glucose was evaluated using the Glucotrend2 bloodglucose test.Results  The  breastfed low birth weight infants had significantlyhigher blood glucose levels (P=0.002)  than  formula-fed low birthweight infants. Mode of delivery  was  related to blood glucose level.Infant delivered  by  caesarean section had significantly differentblood glucose levels  at  1 hour  (P=0.005)  and  72  hours afterbirth (P=0.027).  The  full-term infants had significantly higherblood glucose level (P=0.007)  than  the small for gestational ageinfants.Conclusions  Generally,  low  birth weight infants have hypoglycemiaafter first hour  of  delivery. Breastfed low birth weight infants havehigher blood glucose levels  than  formula-fed low birth weightinfants.
Comparison of blood glucose level between breast--fed and formula--fed term babies Omar Sazali Aldy; Bugis M Lubis; Pertin Sianturi; Emil Azlin; Guslihan D. Tjipta
Paediatrica Indonesiana Vol 48 No 4 (2008): July 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi48.4.2008.209-13

Abstract

Background Hypoglycemia is common in newborns in the firstfew hours after birth. This may also occur in term babies. Dataof hypoglycemia in breastfed and formula-fed infants have beenlimited.Objective To compare blood glucose levels between breast-fed andformula-fed healthy term babies at 1, 24 and 48 hours of life.Methods A cross sectional study was performed on 32 neonatesbetween January and March 2007 in the Dr. Pirngadi Hospital.The subjects was classified into two groups, the breastfed andformula-fed groups. Blood glucose level was examined at 1, 24,and 48 hours after birth and level ofless than 2.6 mmol/1 definedthe presence of hypoglycemia.Results There was statistically significant difference in meanblood glucose level at 1 hour of life between breastfed [59.25(SD 3.38) mg/dl] and formula-fed infants [55.96 (SD 8.60) mg/dl], (P=0.049), while no significant difference was found after24 hours of life, i.e., 62.59 (SD 3.57) mg/dl vs. 61.21 (SD 6.87)mg/dl, P=0.319 and also after 48 hours of life, i.e., 67.34 (SD5.18) mg/dl vs. 66.75 (SD 7.76) mg/dl, P=0.720.Conclusion The blood glucose level at one hour after birth wassignificantly different in breastfed compared to formula-fed infants,while no statistically significant difference was found at 24 hoursand 48 hours after birth. The mean blood glucose at 24 hours oflife was lower than that of 48 hours after birth
Pengaruh domperidon terhadap produksi ASI pada ibu yang melahirkan bayi premature Tengku Ellya Fazilla; Guslihan Dasa Tjipta; Emil Azlin; Pertin Sianturi
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 1 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Mother who gave birth to premature babies often have difficulty getting adequate milk production. Various attempts to increase milk production have been made, including pharmacological interventions. One of the drugs that can be used is domperidone. Domperidone is a peripheral dopamine receptor antagonist, works by blocking the inhibitory effects of dopamine-mediated prolactin secretion, thereby increasing milk production. Three randomized double-blind study showed that domperidon can increase milk production without causing any side effects to the mother and baby.Keywords : domperidone; premature; breastfed
Terapi antibiotika empiris pada neonatus Muchtar Kusuma Hayatullah; Guslihan Dasa Tjipta; Pertin Sianturi; Emil Azlin; Bugis Mardina Lubis; Syamsidah dr; Fera Wahyuni
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 50, No 2 (2017): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (166.074 KB)

Abstract

Neonatal sepsis is a clinical syndrome with symptoms of systemic infection and followed by bacteremia in the first month of life. Antibotic initial therapy empirically is often given concomittantly awaiting the results of blood cultures in neonates with suspected sepsis. The recommended initial treatment in general is a combination of ampicillin and aminoglycoside (gentamicin). Alternative to aminoglycosides is the third-generation cephalosporins (eg cefotaxime). This regimen was found safe and effective by appropriate duration of therapy. This therapy should be evaluated every 48 hours with a lingering risk of therapy associated with increased risk of necrotizing enterocolitis and death.Keyword : antibotic initial, Neonatal sepsis
Osteopenia prematuritas dan upaya pencegahannya Febriyanti Mobilina; Guslihan Dasa Tjipta; Emil Azlin; Pertin Sianturi; Bugis Mardina Lubis; Beby Syofiani Hasibuan
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 47, No 3 (2014): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Osteopenia of prematurity is a common problem encountered in preterm infants or infant with low birth weight. This is characterized by decreased bone mineral content due to inadequat nutritional intake and biochemical factors. This condition can make metabolic disorders in pathological bone fractures even in newborns. Incidence of osteopenia in low birth weight infants in 30%, whereas in infants less than 1000 g of about 55%, and infants less than 1500 g as much as 23%. For preterm infants, the features commonly associated with fracture are delivery at less than 28 weeks of gestation. Metabolic bone disease is often not detected at early stage and became known after appearing obvious abnormalities in the bone or in radiologic examination. Therefore, it is necessary to screening with serum biochemical examination of blood in serum levels of calcium, phosphate and alkaline phosphatase. In addition, it was important to intake of calcium and phosphorus are sufficient for bone mineralization. Key word : osteopenia of prematurity, preterm, calcium, calcium
Co-Authors Amir Syarifuddin Batubara, Ratna Suwita Beby Syofiani, Beby Bistok Saing Bugis M Lubis Bugis M. Lubis Bugis Mardina Lubis Bugis Mardina Lubis, Bugis Mardina Dasa Tjipta, Guslihan Destariani, Cynthea Prima Dimyati, Yazid Eli Tua Pangaribuan Emil Azlin Febriyanti Marito Lubis, Nikmah Febriyanti Mobilina Fera Wahyuni Guslihan D. Tjipta Guslihan Dasa Tjipta Guslihan Dasa Tjipta, Guslihan Dasa Handayani Ardy, Nurul Mardina Lubis, Bugis Muchtar Kusuma Hayatullah Omar Sazali Aldy Saing, Johannes Harlan Sitanggang, Fitri Parinda Syamsidah dr Syamsidah Lubis, Syamsidah Syofiani Hasibuan, Beby Tengku Ellya Fazilla Wahyuni, Fera