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All Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Majalah Farmaseutik
Tri Murti Andayani
Fakultas Farmasi, Universitas Gadjah Mada,Yogyakarta
Health Professions Medicine & Pharmacology Public Health

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Analisis Kualitas Hidup Pasien Diabetes Melitus Tipe 2 Berdasarkan Pola Peresepan Antidiabetik dan Komplikasi Pande Made Desy Ratnasari; Tri Murti Andayani; Dwi Endarti
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 9, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (7130.477 KB) | DOI: 10.22146/jmpf.45862

Abstract

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that requires lifelong therapy to control blood glucose. The long term use and different mechanism of action antidiabetic have the potential cause side effects and discomfort that affects the quality of life. This study aimed to determine differences in the quality of life of patients with T2DM based on antidiabetic prescribed and complications at the Outpatient of Panembahan Senopati Bantul Yogyakarta Hospital in September 2017. This research is observational with a cross-sectional design. Quality of life data is taking concurrently using the Diabetes Quality of Life Clinical Trial Questionnaire and patient's medical record. This study involved 200 T2DM patients who received antidiabetic at least 3 months before study, aged ≥18 years and agreed to inform concent. Sociodemographic data, antidiabetic prescribed and complications were described descriptively. Differences in the quality of life based on antidiabetic prescribed and complications using the Kruskal Wallis test which was further analyzed using the post hoc by Mann Whitney test. The results showed the majority of patients received oral combination with insulin (48.5%) and dominated by macrovascular complications (19.5%). The average value of patient's quality of life is 65.7. There was difference quality of life based on antidiabetic prescribed in the domain of treatment satisfaction (p=0.000) between oral monotherapy with combination of oral and insulin (p=0.000) and insulin monotherapy with combination of oral and insulin (p=0.002). There were differences in quality of life based on complications in the mental health domain (p=0.003) between macrovascular and microvascular (p=0.011) and between microvascular and without complications (p=0.001).
Analisis Luaran Klinik Pasien Diabetes Melitus Tipe 2 Berdasarkan Peresepan Antidiabetik dan Komplikasi Pande Made Desy Ratnasari; Tri Murti Andayani; Dwi Endarti
Majalah Farmaseutik Vol 16, No 2 (2020)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (285.242 KB) | DOI: 10.22146/farmaseutik.v16i2.50566

Abstract

Diabetes Melitus (DM) tipe 2 merupakan penyakit metabolik kronis yang membutuhkan terapi antidiabetik seumur hidup guna mengontrol glukosa darah serta mencegah terjadinya komplikasi. Peresepan antidiabetik yang diberikan kepada pasien serta terjadinya komplikasi dapat mempengaruhi luaran klinik yaitu glukosa darah sewaktu (GDS). Tujuan penelitian ini untuk mengetahui perbedaan  luaran klinik  berdasarkan peresepan antidiabetik dan jenis komplikasi.  Rancangan penelitian adalah deskriptif analitik dengan desain cross sectional. Subyek penelitian adalah pasien DM tipe 2 dengan usia ≥18 tahun yang memperoleh antidiabetik secara rutin minimal 3 bulan sebelum penelitian Di Instalasi Rawat Jalan RSUD Panembahan Senopati Bantul Yogyakarta periode September 2017. Pengambilan data dilakukan secara retrospektif berdasarkan rekam medik dengan teknik purposive sampling. Analisis data demografi dan perbedaan luaran klinik berdasarkan peresepan antidiabetik dilakukan secara deskriptif. Uji Chi-square digunakan untuk melihat perbedaan luaran klinik berdasarkan jenis komplikasi. Hasil penelitian menunjukkan sebesar 48,5% pasien memperoleh kombinasi antidiabetik oral dan insulin, sedangkan terjadinya komplikasi didominasi makrovaskuler (19,5%). Terdapat perbedaan luaran klinik berdasarkan peresepan antidiabetik dan komplikasi (p=0,009). Pasien dengan kombinasi oral serta pasien tanpa komplikasi menunjukkan luaran klinik yang terkontrol paling tinggi.
Co-Authors Pande Made Desy Ratnasari