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All Journal Proceedings of the International Conference on Applied Science and Health
Maya Erisna
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Education Health Professions Medicine & Pharmacology Nursing Public Health

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DOES BEETROOT JUICE LOWER BLOOD PRESSURE?: A SYSTEMATIC REVIEW Maya Erisna; Merisa Restiani Arma; Sri Sumarni; Hilma Triana
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Hypertension or high blood pressure has been a common global health problem for several years. The content of nitrate within beetroot helps to increase production of nitric oxide (NO) which serves as a vasodilator and has potency to reduce blood pressure. This study aims to determine the potential effect of beetroot juice on reducing blood pressure.Methods: This study was a systematic review based on the PRISMA protocol as a writing guideline. Data were obtained from PubMed, Science Direct, and Google Scholar databases. Keywords used consisted of “beetroot”, “beetroot juice”, “blood pressure”, and “hypertension.” The eligibility criteria were research written in English, years of publication from 2014 and above, and Randomized controlled trials of beetroot juice interventions on reducing blood pressure.Results: The literature search resulted in 376 records, and only 9 studies were in the systematic review. Six out of 9 studies showed significant results of blood pressure reduction, but the other three studies confirmed otherwise. A significant reduction of blood pressure was mostly observed in healthy subjects. The efficacy of beetroot juice supplementation is influenced by several factors, including gender, age, nutritional status (BMI), initial blood pressure, duration of supplementation, dose, and concentration of nitrate.Conclusions: Beetroot juice supplementation is not so useful on reducing blood pressure because it only has an acute effect in lowering blood pressure and its effects were also influenced by several factors.
POTENTIAL OF HERBAL PLANTS AS ANTIHYPERTENSIVE THERAPY: A REVIEW Merisa Restiani Arma; Maya Erisna; Sri Sumarni
Proceedings of the International Conference on Applied Science and Health No. 4 (2019)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

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Background: Hypertension has become a significant health problem in the world which the sufferer increases every year. Herbal treatment for lowering blood pressure that has been widely used in many countries shows the potential as an anti-hypertensive. This study aims to provide an overview of the herbs that have the effect of lowering blood pressures as the treatment of hypertension.Methods: This study used a systematic review based on the PRISMA (Preferred Reporting Items for Systematic Reviews & Meta-Analyses) protocol as a writing guideline. Electronic databases used in this study were Science Direct, PubMed, and Google Scholar. Only articles using interventions research design and containing full text both in English and Indonesian language were included in this study.Results: Of 207 articles recorded in the searching literature, only fourteen articles were included in this study. Study found that herbs which had the effect as antihypertensive therapy were Apium graviolens, Allium sativum, Centella asiatica, Orthosiphon stamineus benth, Beta vulgaris, and Vitis vinifera. The main components of those herbs consisted of n-butylphthalide, apigenin, potassium, flavonoids, triterpenoid, polysulfide, sinensetin, nitrate, and polyphenols. Conclusions: Many herbal plants found potentially lowering the blood pressures and considered as complementary treatment without any side effects. Further research is still needed on the effects of herbs in lowering the blood pressure to the human subject and its reversible effects, as well as the safety of herbs to human health when it is used for a long time.
Co-Authors Hilma Triana Merisa Restiani Arma Sri Sumarni