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PENGARUH METODE SENAM IRAMA TERHADAP MOTORIK KASAR ANAK USIA 5-6 TAHUN DI TK ISLAM AL-AZHAR KOTA CIREBON Sundari, Sri; Yudha, Rivo Panji
Jurnal Olahraga Vol 3 No 1 (2017): Jurnal Olahraga
Publisher : STKIP Pasundan

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Abstract

The purpose of this study was to determine the effect of rhythmic gymnastics on body balance, limb coordination, limb flexibility and limb strength of children aged 5-6 years using a quantitative approach with Pre Experimental with a pretest-posttest with control group design. The study population was all students in Al-Azhar Islamic Kindergarten in Cirebon. Variable X is the Rhythmic Gymnastics Method, and the Y variable is the Gross Motoric Development of Children Aged 5-6 Years The study sample consisted of 15 students using purposive sampling techniques. Data collection techniques used are observation and documentation. Data analysis uses the Independent Sample T Test. The results showed that the average sample after performing the rhythmic gymnastic method was able to increase the children's gross motor skills by an average of 259.00 in the experimental group and 277.33 in the control group. From these results it can be analyzed that all samples of the experimental group have the same results, namely gross motor children after doing more Rhythmic Gymnastics. The conclusion of the study was that there was an effect of the rhythmic gymnastic method on gross motor skills of children aged 5-6 years in the experimental group of 259.00 and in the control group of 277.33 in Al-Azhar Kindergarten students in Cirebon. Suggestions from this study are Al-Azhar Kindergarten students in Cirebon City to routinely do exercises at least 3 times a week.
The Effectiveness of Pregnant Women Class to Increase Knowledge and Hemoglobin Level Husna, Putri Halimu; Purwandari, Kristiana Puji; Mawarni, Siti; Sundari, Sri; Wardani, Indah Kusuma; Maryati, Maryati
Journal of Maternal and Child Health Vol 5, No 1 (2020)
Publisher : Journal of Maternal and Child Health

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Abstract

Background: Intrauterine Fetal Death (IUFD) is a birth process of a conception result in a state of death. It is also a contributor to death for Infant Mortality Rate (IMR). Pregnant Woman Class is a government effort to reduce IMR. However, the implementation has not been maximized. This stu­dy aimed to determine the effectiveness of pregnant woman class in increasing the level of know­ledge and hemoglobin (Hb) levels of the pregnant woman.Subjects and Method: This was a Randomized Controlled Trial (RCT). The population of the stu­dy consisted of 170 pregnant women was selected randomly from 3 Community Health Centers with the highest infant mortality rates. The dependent variables were knowledge and Hb levels. The independent variable was pregnant woman class. The level of knowledge was measured by ques­tionnaire with Cronbach's alpha by 0.64. Hb level was measured with Easy Touch GCHB. The Mean differences in knowledge and Hb between pregnant wo­men class and control groups, before and after participating in pregnant woman class, were tested by independent t-tests.Results: Before the intervention, the level of knowledge of the pregnant women class group (Mean= 31.07; SD=8.21) was comparable with the control group (Mean=29.30; SD=8.22), with p=0.162. It indicated the randomization success. After the intervention, the level of knowledge of preg­nant woman class group (Mean=35.07; SD=2.24) was higher than the control group (Mean= 29.10; SD= 4.77), and it was statistically significant (p<0.001). It indicated that the pregnant woman class was effective in increasing the knowledge of pregnant women. Before the inter­vention, the Hb level of pregnant woman class group (Mean=11.92, SD=2.18) was comparable with the con­trol group (Mean= 11.44; SD= 2.05), with p=0.162. It indicated the randomization success. After the inter­vention, the Hb level of the pregnant woman class group (Mean = 12.82; SD = 0.92) was higher than the control group (Mean=11.56; SD=1.05), and it was statistically significant (p<0.001). It showed that pregnant woman class was effective in increasing the Hb level of preg­nant women.Conclusion: Pregnant woman class was effective in increasing the knowledge and the Hb level of preg­nant women.Keywords: pregnant woman class, knowledge, hemoglobin, IUFDCorrespondence: Putri Halimu Husna. Nursing Academy of Giri Satria Husada Wonogiri. Jl. Tentara Pelajar 01 Giriwono, Wonogiri 57613, Central Java. Email: ns.haha354@gmail.com. Mobile: +622­73322610, +6281391277044.Journal of Maternal and Child Health (2020), 5(1): 50-57https://doi.org/10.26911/thejmch.2020.05.01.06
MODEL PENGEMBANGAN MOTIVASI DAN PARTISIPASI ANGGOTA DALAM MENINGKATKAN PELAYANAN SERTA KINERJA KOPERASI DI KPRI UNIVERSITAS JEMBER Sundari, Sri; Anggraeni, Oktanita Jaya
PROFIT: JURNAL ADMINISTRASI BISNIS Vol 1, No 2 (2007)
Publisher : FIA UB

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Abstract

This paper tries ti find out a model in upgrading motivation and participation of cooperation members as one way to increase their service quality. In General, cooperation has three goals, i.e business success, members success, and community development success. The are some barriers faced by them in catching their purposes, i.e limited modal, technology, market access, production quality and simple management. Basically, members of cooperation have to positions (dual identity), as owner and user of cooperation. Consequantly, a cooperation success means that the members can fulfill their both needs as the user and the owner
Daya Antihelmintik Nanas (Ananas comocus) terhadap Ascaris lumbricoides secara In Vitro Adli, Jeri; Sundari, Sri
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 8, No 2 (s) (2008): Oktober
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v8i2 (s).1633

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Ascariasis is one disease with high risk. In long time ago, Indonesian people was using traditional medicine from plant and animal, but nothing study to research it. The aim of this study is to determine the antihelmintic effect ofpineapple for Ascaris. The method of this study is experimental, the collected data with cohort. The sample is ascaris with same size, the gender is woman. The study using Pyrantel Pamoat, NaCl 0,9% and pineapple with any concentration.This research used 8 groups of experiment, they were 6 groups consisted of pineapple in 100%,75%,505,25%,10% and 5% and 2 groups of control used physiological salt and pirantel pamoat 0,236%. Result of this research showed that concentration of pineapple extract 100% there was non significant difference(P 0,05) within pirantel pamoat. Concentration ofpineapple extract 75%,50%,25%,10% and 5% had significant difference(P 0,05) with pirantel pamoat. Probhit analyze is got LD 50 pineapple extract (ananas comocus) is 20.50314% with the boundary gyration of under 13.83529 and boundary gyration to the 30.38451.LD 90 Pineapple extract is 81.05742 with the boundary gyration of under 40.94076 and boundary gyration to the 160.4833.While LD 95 from Pineapple extract is 119.6979 with the boundary gyration of under 52.37216 and boundary gyration to the 273.5727. In conclusion, Pineapple (Ananas comocus) have antihelminthic effect for Ascaris but the dose more better than Pyrantel Pamoat.Ascariasis adalah salah satu penyakit dengan resiko tinggi. Sejas dahulu kala orang Indonesia memakai obat tradisional dari tanaman dan hewan tetapi belum ada penelitian yang mengkaji hal tersebut. Tujuan penelitian ini adalah untuk mengkaji efek antihenmintik buah nanas terhadap Ascaris lumbricoies. Desain penelitian adalah eksperimental dengan data dikoleksi secara cohort. Sampel adalah Ascaris dengan ukuran dan jenis kelamin sama yaitu betina. Penelitian dengan Pyrantel Pamoat, NaCl 0,9% dan buah nanas dalam beberapa konsentrasi. Ada 8 kelompok yaitu 6 kelompok buah nanas dengan konsentrasi 100%,75%,505,25%,10% dan 5%, serta 2 kelompok control dengan garam fisiologis dan pirantel pamoat 0,236%. Hasil penelitian menunjukkan bahwa buah nanas 100% tidak berbeda bermakna (p 0,05) dengan pirantel pamoat, buah nanas konsentrasi 75%,50%,25%,10% dan 5% berbeda bermakna (p 0,05) dengan pirantel pamoat. Hasil analisis Probit menunjukkan bahwa. Lethal Dosis 50 (LD 50) perasan nanas adalah 20.50314%. Lethal Dosis 90 (LD 90) perasan nanas adalah 81.05742%. Lethal Dosis 95 (LD 95) perasan nanas adalah 116.6979. Dapat disimpulkan bahwa perasan nanas (Ananas comocus) mempunyai daya antihelmintik terhadap Ascaris lumbricoides.
Pengetahuan tentang Penyakit Menular Seksual, Sikap dan Perilaku Seks Bebas pada Siswa Sekolah Menengah Atas Islam dan Umum di Yogyakarta Kesetyaningsih, Tri Wulandari; Majdawati, Ana; Sundari, Sri
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 15, No 2 (2015)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v15i2.3758

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Penyakit menular seksual/PMS berkaitan dengan perilaku seksual tidak sehat. Siswa SMA  berusia remaja, memiliki dorongan seksual tinggi. Islam mengatur perilaku seksual dalam kitab suci. Kurikulum pendidikan agama di SMA Islam lebih banyak. Penelitian ini bertujuan untuk mengungkap perbedaan pengetahuan, sikap dan perilaku seksual antara siswa SMA Islam dan umum. Penelitian ini bersifat survei analitik dengan subyek siswa SMA sebanyak 288 orang. Skor pengetahuan, sikap dan perilaku diperoleh dari kuesioner dan dianalisis dengan Anova untuk mengetahui perbedaan variabel diantara siswa. Hasil menunjukkan skor Pengetahuan: Islam putri 64,56; umum 60,02; Islam putra 55,73). Ada perbedaan pengetahuan diantara siswa (p= 0,008) tetapi antara Islam putra-umum tidak berbeda. Sikap: Skor Islam putri 98,75; umum 93,50; Islam putra 92,82. Ada perbedaan sikap diantara siswa (p=0,002); tetapi antara Islam putra-umum tidak berbeda (p=0,072). Perilaku: 13-45% siswa memiliki pacar; 0-2% melakukan koitus (umum 2%, Islam putra 1,1%, Islam putri 0%). Disimpulkan bahwa pengetahuan tentang kesehatan reproduksi, sikap dan perilaku siswa SMA Islam putri lebih baik daripada siswa SMA umum dan siswa SMA Islam putra. Siswa SMA umum lebih banyak berperilaku seksual tidak sehat daripada siswa SMA Islam putra maupun putri.Sexually transmitted diseases are associated with unhealthy sexual behavior. High school (SMA) students are teenagers which have a high sex drive. Islam regulates sexual behavior in the scriptures. Religious education in Islamic SMA is more than in general. This study aims to reveal differences in knowledge, attitudes and sexual behavior between Islamic and general high school students. This research is an analytic survey with the subjects of 288 high school students. Score of knowledge, attitude and behavior obtained from questionnaire and analyzed by Anova to know the difference of variables among students. The knowledge’s scores are: Islamic female 64.56; general 60.02; Islamic male 55.73). There is differs among students (p = 0.008) but Islamic male-general is no different. Attitude’s score are: Islamic female 98.75; general 93.50; Islamic male 92.82. There is differs among students (p = 0.002) but Islamic male-general is no different (p = 0.072). Behavior: 13-45% of students have boy/girlfriends; 0-2% did coitus (general 2%, Islamic male 1.1% and Islamic female 0%). It was concluded that knowledge about reproductive health, attitudes and behavior of female high school students of Islam is better than general high school students and high school students of Islam. Students from general high schools are more sexually unhealthy than male and female students from Islamic High School.
Antibiotik Linkomisin M sebagai Antimalaria terhadap Mencit Swiss Terinfeksi Plasmodium berghei Sundari, Sri
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 9, No 2 (2009)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v9i2.1604

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Malaria is one among the most important public health problems in tropical countries like Indonesia. Several actions have been taken to overcome this problem, however its prevalence is still high. Parasite resistance to antimalarial drug and vector resistance to insecticide are the major constrains in controlling the disease. To overcome this problem an alternative drugs are essentially need to be found. The antibiotic lincomycine is an example of alternative drug, and has been used in combination with chloroquine.. This aim of this study is to assess the effect of linkomycine on Swiss mice infected by Plasmodium berghei and will be compared to antimalarial drug of chloroquine. Fibe groups, each consisted of 5 female Swiss mice were used and Plasmodium berghei were inoculated. Group 1 is positive control who reseiving 100 mg/kg BW, 200 mg/kg BW and 300 mg/kg BW oAll drugs were given twice daily for 5 days. The degree of parasitemia were examinated daily using thin blood smears up to 5 days from inoculation and were analyzed by log-probit metod. The study showed that linkomycine 200 mg/kg BW and linkomycine 300 mg/kg BW were cured on Swiss mice infected by Plasmodium berghei. Effective dosage 50 of linkomycine is 3,707 mg/kg BW and effective dosage 90 is 39,125 mg/kg BW.Malaria sampai saat ini masih merupakan masalah kesehatan masyarakat yang penting terutama di Negara-negara tropis termasuk Indonesia. Berbagai upaya telah dilakukan untuk pemberantasan malaria tetapi prevalensi malaria masih tetap tinggi disebabkan berbagai hambatan diantaranya adanya resistensi vektor terhadap insektisida dan resistensi parasit terhadap obat antimalaria. Adanya permasalahan tersebut mendorong untuk mencari alternatif obat yang dapat diperoleh dengan mudah dan telah dikenal oleh masyarakat luas bahkan mungkin telah lama digunakan, salah satunya dengan menggunakan antibiotika. Diantara antibiotika tersebut adalah linkomisin yang pernah digunakan sebagai antimalaria dengan cara dikombinasi dengan obat-obat yang lain yang termasuk dalam antimalaria sendiri. Penelitian ini bertujuan untuk mengetahui efek linkomisin terhadap mencit Swiss yang terinfeksi Plasamodium berghei jika dibandingkan dengan klorokuin. Lima kelompok perlakukan yang masing-masing terdiri dari 5 ekor mencit betina yang diinokulasi Plasmodium berghei. Kelompok I sebagai kontrol positif mendapatkan pengobatan klorokuin 25 mg/kg BB, kelompok II sebagai kontrol negatif tidak mendapatkan pengobatan apapun. Kelompok III, IV, dan V masing-masing mendapatkan pengobatan linkomisin 100 mg/kgBB, 200 mg/kgBB, dan 300 mg/kgBB. Setiap kelompok mencit diberikan pengobatan secara oral 2 kali sehari selama 5 hari. Pemeriksaan angka parasitemia dilakukan setiap hari dengan pemeriksaan apus darah tipis yang diambil dari ekor mencit. Dosis efektif (ED) 50, ED-90 dihitung dengan analisis probit. Hasil penelitian menunnjukkan bahwa linkomisin 200 mg/kgBB dan 300 mg/kgBB mampu menekan pertumbuhan parasit sehingga mencit bebas parasit. Dari hasil analisis probit ED-50 linkomisin 3,707 mg/kgBB, dan ED-90 adalah 39,125 mg/kgBB.
Deteksi Resistensi Insektisida Nyamuk Aedes Aegypti Berdasarkan Aktifitas Enzim Glutation S-Transferase Sundari, Sri; Orbayinah, Salmah
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 10, No 1 (2010)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v10i1.1563

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Organophosphate insecticide especially temephos and malathion have been used to eliminate mosquito and larvae Aedes aegypti in Yogyakarta province since 1974 up to now. Using by unappropriate chemical insecticide in long term causes resistance of mosquito to the insecticide. It indicates the increasing of Glutation-S-transferase and hydrolyses activity.The biochemical research method conducted at 1995 in Yogyakarta demonstrsted that mosquito and larvae Ae.aegypti based on enzyme esterase activity tend to be resist to organophosphate insecticide. The purpose of this research is to evaluate the resistance status of Ae. Aegypti mosquito to malathion insecticide in some villages in Bantul district based on Glutation-S- transferase activity. This research design was cross sectional study . Sample was collected randomly from these villages : Badegan, Palbapang and Bogoran in Bantul District. There were 48 mosquitos taken for examination of Glutation-S-tranferase activity.The result of examination based on Glutation-S-tranferase activity showed that the average of Ae. Aegypti mosquito resistance in three villages of Bantul District such as: moderate resistance (RS) 15%, susceptible (SS) 85%. However, statitiscally, there was no significant difference of resistance status of mosquito among three villages based on Glutation-S-tranferase (p 0,05).Insektisida kimia organofosfat (OP), khususnya temefos dan malathion selalu dipakai untuk memberantas Aedes aegypti stadium dewasa dan larva di Daerah Istimewa Yogyakarta sejak tahun 1974. Penggunaan insektisida dengan dosis yang kurang tepat dalam jangka waktu yang lama akan menyebabkan resistensi nyamuk terhadap insektisida. Keadaan ini akan ditandai dengan peningkatan aktifitas enzim Glutation-S-transferase dan hidrolase. Penelitian yang dilakukan pada tahun 1995 melaporkan bahwa sudah terjadi kecenderungan resistensi nyamuk dan larva Ae. Aegypti terhadap organofosfat di Yogyakarta yang didasarkan pada aktifitas enzim esterase. Tujuan penelitian ini adalah untuk mengetahui tingkat resistensi nyamuk Ae. Aegypti di beberapa wilayah Bantul yang didasarkan pada aktifitas enzim Glutation-S- transferase. Penelitian ini merupakan penelitian analitik nonparamerik dengan desain cross sectional. Penentuan sampel dengan sampel random sampling dari 3 wilayah di Kabupaten Bantul yaitu Badegan, Palbapang dan Bogoran. Dari masing- masing wilayah diambil 48 nyamuk yang dilakukan pemeriksaan Glutation-S- transferase. Hasil penelitian yang didasarkan aktifitas ensim Glutation-S- transferase menunjukkan bahwa rata-rata tingkat resistensi nyamuk di 3 wilayah Kabupaten Bantul adalah sebagai berikut: resistensi sedang (RS) 15%, rentan (SS) 85%. Dari hasil analsis statistis diperolah hasil bahwa tidak ada perbedaan yang bermakna status resistensi nyamuk berdasarkan aktifitas Glutation-S- transferase di 3 wilayah tersebut (p 0,05).
Efek Antelmintik Perasan Wortel (Daucus carota) terhadap Ascaridia galli Rahayu, Semmy Damarjatie; Sundari, Sri
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 7, No 1 (s) (2007)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v7i1 (s).1683

Abstract

Carrot (Daucus carota) is one of traditional medicine that used as worm remedy, because of more safety, inexpensive and easily obtained by people. Quercitrin is flavonoid within carrot that supposed to have anthelmintic activity. This research aimed to know the efficacy of carrot juice as an anthelmintic against Ascaridia galli. It was experimental research in laboratory. This research consist of six groups, they were four treatment groups consist of carrot juice in concentration of100 %, 75 %, 50 % and 25 %; one group of negative control using physiological salt solution and one group of pyrantel pamoate 0.236% as positive control group. Ascaridia galli worms were soaked in 25 ml of test material solution and observed the death time. The data was analyzed by one way anova test to determine the significantly of difference among the research groups. The result of this research indicated that carrot juice 100 %, 75%, 50% and25% were able to kill the worm in average on 4.7; 5.3; 6.3 and 8.3 hours respectively. The average worm ’s life span in negative control group and positive control group was 16.7 and 4 hours respectively. The result of Anova analysis shows that in concentration 100 % and 75 % of carrot juice there was unsignificantly different (p 0.05) with pyrantel pamoate. In concentration of 50 % and 25 % there was significantly different (p 0.05) with pyrantel pamoate. It is concluded that carrot juice (Daucus carota) have an anthelmintic effect against to Ascaridia galli invitro. The lower concentration, the lesser anthelmintic effect.Wortel (Daucus carota) merupakan salah satu obat tradisional yang sering digunakan sebagai obat cacing di masyarakat. Hal ini karena ada anggapan bahwa pengobatan tradisional lebih aman, murah, dan mudah didapat. Quercitrin yaitu flavonoid yang terdapat pada wortel diduga mempunyai aktivitas antelmintik. Penelitian ini bertujuan membuktikan efek antelmintik perasan wortel terhadap cacing Ascaridia galli. Penelitian ini merupakan penelitian eksperimental laboratorium. Penelitian ini menggunakan 6 kelompok percobaan, yaitu empat kelompok perlakuan perasan wortel 100 %, 75 %, 50 % dan 25 %, kelompok kontrol negatif (NaCl fisiologis) dan kelompok kontrol positif (Pirantel Pamoat 0,236 %). Cacing Ascaridia galli direndam dalam larutan bahan uji sebanyak 25 ml dan dicatat waktu kematiannya. Data dianalisis dengan Anova satujalan untuk menentukan signifikansi perbedaan antar kelompok penelitian.  Hasil penelitian menunjukkan bahwa perasan wortel 100 %, 75 %, 50 % dan 25 % mampu membunuh cacing dengan rerata waktu berturut-turut adalah 4,67; 5,3; 6,3 dan 8,3 jam. Rerata lama hidup cacing pada kelompok kontrol negatif dan kontrol positif berturut-turut adalah 16,7 dan 4 jam. Hasil dengan uji Anova menunjukkan perasan wortel konsentrasi 100 % dan 75 % menunjukkan perbedaan yang tidak bermakna (p 0,05) dengan Pirantel Pamoat, sedangkan pada konsentrasi 50 % dan 25 % mempunyai perbedaan yang bermakna (p 0,05) dengan Pirantel Pamoat. Disimpulkan bahwa perasan wortel (Daucus corota) mempunyai daya antelmintik terhadap cacing Ascaridiagalli. Makin rendah konsentrasi perasan makin berkurang daya antihelmintiknya.
Pengobatan Malaria Melalui Target Enzim Sundari, Sri
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 1, No 2 (2001)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v1i2.1905

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Plasmodium falciparum causes the most severe form of malaria which is fatal in many cases. The emergence of drug-resistant strains of P. falciparum to the standard therapy of malaria (i.e. kloroquin) requires the new drug en¬zyme targets to be identified. This review covers in details: the enzymes of purin salvage pathway; pyrimidine biosynthesis; protease involved in catabo¬lism on haemoglobin. The review also briefly touches upon other potential targets in the treatment of malaria falciparum.kPlasmodium falciparum menyebabkan bentuk penyakit malaria yang paling berat yang menyebabkan kematian dalam banyak kasus. Munculnya strain-strain P. falciparum yang resisten obat antimalaria (yaitu klorokuin) mengharuskan untuk menggali target enzim obat baru yang dapat digunakan untuk pengobatan malaria. Tinjauan ini membicarakan secara detil tentang: enzim-enzim dalam proses metabolisme purin; biosintesis pirimidin dan protease yang terlibat dalam katabolisme hemoglobin. Selain itu, secara singkat tinjauan ini juga akan membicarakan tentang target enzim potensial lainnya untuk terapi malaria falciparum.
PENINGKATAN HASIL BELAJAR KOGNITIF DAN HARGA DIRI MAHASISWA MELALUI METODE COOPERATIVE LEARNING TIPE JIGSAW Purnamasari, Vita; Sundari, Sri; Suryandari, Galuh
IJNP (Indonesian Journal of Nursing Practices) Vol 1, No 1 (2016): Indonesian Journal Of Nursing Practices
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (386.981 KB) | DOI: 10.18196/ijnp.v1i1.3420

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Cooperative Learning Jigsaw type is an innovative learning, the five principal elements of cooperative jigsaw can improve learning outcomes, interpersonal skills, self esteem and motivation. The purpose of research to determine the effect of cooperative learning on learning outcomes and self-esteem students Stikes Surya Global Yogyakarta. The research design is Quasy Experimental design of posttest pretest with control group design, research subjects of Stikes Surya Global 2nd semester with total sampling, the number of respondents is 221 students. Data analysis using Wilcoxon Signed Rank Test and Mann Whitney Test. The results showed that there were significant differences between intervention group and control group with P = 0.000 for cognitive learning and P = 0.000 for self esteem. The conclusion of this research is Cooperative Learning Jigsaw improve cognitive and student’s self esteem Stikes Surya Global Yogyakarta.