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All Journal IPTEK The Journal for Technology and Science Jurnal Teknik Kimia Journal of Research and Technology Jurnal Ilmu Kesehatan Bhakti Husada: Health Sciences Journal
Susianto Susianto
Institut Teknologi Sepuluh Nopember
Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Nursing Public Health

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Journal : Jurnal Ilmu Kesehatan Bhakti Husada: Health Sciences Journal

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EFEK FORTIFIKASI VITAMIN B12 TERHADAP KADAR VITAMIN B12 SERUM DAN HOMOSISTEIN SERUM PADA VEGETARIAN Susianto, Susianto
Jurnal Ilmu Kesehatan Bhakti Husada: Health Sciences Journal Vol 11 No 1 (2020): Jurnal Ilmu Kesehatan Bhakti Husada: Health Science Journal
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Kesehatan Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (221.77 KB) | DOI: 10.34305/jikbh.v11i1.150

Abstract

Introduction: Vegetarians consume plant-based foods with or without eggs and milk. Vegetarians are at risk of vitamin B12 deficiency, as natural sources of vitamin B12 are limited to animal-based foods. Vitamin B12 deficiency can lead to megaloblastic anemia, nerve damage and increase homocysteine level. Higher homocysteine level can increase the risk of coronary heart disease and stroke. The objective of this study was to investigate the effect of vitamin B12 fortification on the level of serum vitamin B12 and homocysteine in vegetarian. Method: The research design was an experimental study, community trial. The samples were 42 vegetarians with vitamin B12 deficiency (< 156 pmol/L) selected from 118 vegetarians as members of Indonesia Vegetarian Society (IVS) Pekanbaru, treated by vitamin B12 fortified oatmeal for three months from March to June 2010.  Serum vitamin B12 and homocysteine were measured by electrochemiluminescent immunoassay and microparticle enzyme immunoassay method respectively. Result: Prevalence of vitamin B12 deficiency in vegetarian was 35.6%. Statistical analysis showed a significant increase of serum vitamin B12 from 124.6 to 284.6 pmol/L (p=0.001) and significant decrease of serum homocysteine from 20.1 to 15.1 µmol/L (p=0.001). Conclusion: Consumption of vitamin B12 fortified oatmeal increases the level of serum vitamin B12 and decreases the level of serum homocysteine significantly in vegetarian with vitamin B12 deficiency.
Co-Authors Ali Altway Atlway, Ali Fitri, Medya Ayunda Kuswandi Kuswandi Margono Margono Novitrie, Nora Amelia Ratih Permatasari Suhadi Suhadi