Article Per Year (5 Year)
p-Index From 2019 - 2024
0
P-Index
This Author published in this journals
All Journal Jurnal Pengajaran MIPA Jurnal Pengajaran Matematika dan Ilmu Pengetahuan Alam Jurnal Riset Kimia Alchemy Jurnal Penelitian Kimia INDONESIAN JOURNAL OF PHARMACY
Yana M. Syah
Organic Chemistry Division, Institut Teknologi Bandung, Jalan Ganesha 10, Bandung 40132, Indonesia
Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Environmental Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology

Published : 6 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 6 Documents
Search

 1 
SENYAWA DIMER DAN TRIMER RESVERATROL DARI KULIT BATANG DIPTEROCARPUS INTRICATUS (DIPTEROCARPACEAE) DAN AKTIVITAS SITOTOKSIKNYA TERHADAP SEL MURIN LEUKIMIA P-388 Muhtadi, Muhtadi; Hakim, Euis H.; Syah, Yana M.; Juliawaty, Lia D.; Achmad, Sjamsul A.; Latip, Jalifah
Alchemy Jurnal Penelitian Kimia Vol 7, No 1 (2008)
Publisher : Alchemy Jurnal Penelitian Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Dua senyawa oligomer resveratrol, (-)-?-viniferin (2) dan (-)-?-viniferin (3), bersama-sama satu senyawa turunan asam fenolat, bergenin (1) telah berhasil diisolasi untuk pertama kalinya dari ekstrak aseton kulit batang Dipterocarpus intricatus. Struktur molekul senyawa-senyawa tersebut ditetapkan berdasarkan data spektroskopi UV, IR, 1H-NMR dan 13C-NMR serta perbandingan dengan data sejenis yang telah dilaporkan. Senyawa (-)-?-viniferin (2) dan (-)-?-viniferin (3)menunjukkan aktivitas sitotoksik terhadap sel murin leukemia P-388 dengan nilai IC50 masing-masing sebesar 7,8 dan 17,5 ?g/mL.
AMPELOPSIN A DAN α-VINIFERINDARI KULIT BATANG SHOREA GIBBOSA BRANDIS (DIPTEROCARPACEAE) Saroyobudiyono, Haryanto; Hakim, Euis H.; Syah, Yana M.; Achmad, Sjamsul A.; Juliawaty, Lia D.; Latip, Jalifah
Alchemy Jurnal Penelitian Kimia Vol 4, No 2 (2005)
Publisher : Alchemy Jurnal Penelitian Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Dua senyawa oligomer resveratrol yaitu (-)-ampelopsin A dan (-)-?-viniferin, telah berhasil diisolasi untuk pertama kalinya dari ekstrak aseton kulit batang Shorea gibbosa. Struktur senyawa ini telah ditetapkan berdasarkan data spektroskopi UV,IR, 1H NMR, 13C NMR serta melalui perbandingan terhadap data senyawa sama yang telah dilaporkan. Pengujian sifat sitotoksikbterhadap dua senyawa oligomer resveratrol tersebut menunjukkan hasil IC50 berturut-turur adalah 17,0 µg.mL-1 ,dan 18,2 µg.mL-1.
GRANDIFENOL B, SUATU TETRAMER RESVERATROL DARI KULIT BATANG SHOREA PLATYCLADOS (DIPTEROCARPACEAE) Aisyah, Siti; Syah, Yana M.; Hakim, Euis H.; Juliawaty, Lia D.; Latif, Jalifah
Jurnal Pengajaran Matematika dan Ilmu Pengetahuan Alam Vol 8, No 2 (2006): Jurnal Pengajaran MIPA
Publisher : Faculty of Mathematics and Science Education, Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18269/jpmipa.v8i2.333

Abstract

Grandifenol B, suatu tetramer resveratrol yang memiliki unit tetrahidrofuran, telah berhasil diisolasi dari ekstrak aseton kulit batang Shorea platyclados (Dipterocarpaceae). Struktur senyawa ini ditetapkan berdasarkan analisa data spektroskopi UV, IR, NMR 1D dan NMR 2D.  Kata kunci: Dipterocarpaceae, Grandifenol B, Shorea platyclados
Three resveratrol’s oligomers from the stem bark of H. gregaria (dipterocarpaceae) and their toxicity and citotoxicity ., Sahidin; Hakim, Euis H.; Syah, Yana M.; Juliawaty, Lia D.; Achmad, Sjamsul A.; Latip, Jalifah
INDONESIAN JOURNAL OF PHARMACY Vol 17 No 3, 2006
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (246.948 KB) | DOI: 10.14499/indonesianjpharm0iss0pp109-115

Abstract

Three resveratrol oligomers have been isolated from the stem bark of H. gregaria including a resveratrol trimer i.e. α-viniferin (1), and two resveratrol tetramers i.e. vaticanol B (2) and hopeaphenol (3). These structures were determined by spectroscopic evidence including UV, IR, 1H , 13C NMR and compared with that of the reported data in the literatures. Activities of the compounds were determined toward brine shrimp Artemia salina (toxicity) and murine leukemia P-388 cells (cytotoxicity). The compound 1 is the most active against A. salina (LC50 = 49,0 ± 5,8 μg/mL), and the compound 3 has very active level toward murine leukemia P-388 cells (LC50 = 5,7 ± 0,3 μM).Key words : Resveratrol oligomers, H. gregaria, toxicity, and cytotoxicity.
ISOLASI DAN KARAKTERISASI METABOLIT SEKUNDER DARI EKSTRAK ASETON DAUN MACARANGA PRUINOSA BANGKA BELITUNG Roanisca, Occa; Syah, Yana M.
Jurnal Riset Kimia Vol 9, No 2 (2016): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v9i2.248

Abstract

Macaranga is a large genus in Euphorbiaceae, locally known as "Mahang-mahangan", and consisting about 300 species. Distribution of Macaranga is widespread from Africa and Madagascar in the west to the tropical regions of Asia including Indonesia. Based on previous research of the M. pruinosa, secondary metabolites that have been reported are flavonoid, and stilbenoid derivatives from Borneo. M. pruinosa that grow in South Sumatra produce poilanoat acid (diterpene). Therefore, this research is done to investigate phytochemical constituent of leaves of M. pruinosa from Bangka Belitung Islands. Isolation is done by maceration in acetone, separation and purification using vacuum liquid chromatography and radial chromatography. Structure determination were elucidated by 1H-NMR,13C-NMR, 2D NMR. Two compounds are identified as flavanon derivatives. They are nymphaeol B, and 6-farnesil-3',4',5,7-tetrahidroksiflavanon. These compounds are substituted with terphenyl group, known as geranyl (C10), and farnesyl (C15). Nymphaeol B (1) and compound of 6-farnesil-3', 4', 5,7-tetrahidroksiflavanon (2) have been found in other species of Macaranga. In conclusion, we here acquired two phenolic derivatives substituted by terphenyl groups from acetone extracts of leaves of M. pruinosa from Bangka Belitung. They are nymphaeol B, and 6-farnesil-3',4',5,7-tetrahidroksiflavanon. The result showed that M.pruinosa can produce different secondary metabolites depend on where they grow. 
GRANDIFENOL B, SUATU TETRAMER RESVERATROL DARI KULIT BATANG SHOREA PLATYCLADOS (DIPTEROCARPACEAE) Aisyah, Siti; Syah, Yana M.; Hakim, Euis H.; Juliawaty, Lia D.; Latif, Jalifah
Jurnal Pengajaran MIPA Vol 8, No 2 (2006): JPMIPA: Volume 8, Issue 2, 2006
Publisher : Faculty of Mathematics and Science Education, Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18269/jpmipa.v8i2.35692

Abstract

Grandifenol B, suatu tetramer resveratrol yang memiliki unit tetrahidrofuran, telah berhasil diisolasi dari ekstrak aseton kulit batang Shorea platyclados (Dipterocarpaceae). Struktur senyawa ini ditetapkan berdasarkan analisa data spektroskopi UV, IR, NMR 1D dan NMR 2D.
Co-Authors Euis H. Hakim Haryanto Saroyobudiyono, Haryanto Ikram M. Said Jalifah Latif Jalifah Latip Kholifatu Rosyidah Laily Bin Din Lia D. Juliawati Lia D. Juliawaty Lukman Makmur Muhtadi Muhtadi Roanisca, Occa Sahidin ., Sahidin Siti Aisyah Sjamsul A. Achmad