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All Journal Respiratory Science
Dina Octafrida Marpaung
Universitas Sumatera Utara
Health Professions Medicine & Pharmacology

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The Association Between Vitamin D Receptor Gene FokI Polymorphism and Pulmonary Tuberculosis Dina Octafrida Marpaung; Bintang Yinke Magdalena Sinaga; Parluhutan Siagian; Erna Mutiara
Respiratory Science Vol. 2 No. 1 (2021): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i1.29

Abstract

Backgrounds: There is a wide range of individual responses to mycobacterium infection. However, the reason why certain people suffers from a disease when they are infected with mycobacterium while others remain healthy is still unknown. Genetic susceptibility is thought to be one of the important explanatory factors for individuals with the risk of developing pulmonary tuberculosis (TB). FokI polymorphism was one of the genetic variations within the vitamin D receptor (VDR) gene associated with pulmonary TB. In the present study, we investigated the association between VDR gene FokI polymorphism and pulmonary TB. Conclusion: There was no significant association between the VDR gene FokI polymorphism and pulmonary TB.
Co-Authors Bintang Yinke Magdalena Sinaga Erna Mutiara Parluhutan Siagian