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Rita Tjokropranoto
Deptartment Parasitology Medical Faculty of Maranatha Christian University, Jl. Prof. drg. Suria Sumantri, MPH no.65 Bandung 40164
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Effects of Pomegranate Peel (Punica granatum L.) Extract as an Anthelmintic Amelia, Monica; Jasaputra, Diana K; Tjokropranoto, Rita
Journal of Medicine and Health Vol 1, No 5 (2017)
Publisher : Maranatha Christian University

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Abstract

Helminths infections caused by Soil-Transmitted Helminths (STH) are found in manypeople living in developing countries, especially in rural areas. People often use pomegranate asan anthelmintic. The aim of this research is to find out the effects of pomegranate peel (Punicagranatum L.) as an anthelmintic to female Ascaris suum in vitro. The research on the effects ofpomegranate peel extract has been conducted on 900 female Ascaris suum in vitro. Ascaris suumare divided into 5 groups, group I: pomegranate peel extract of dose 25%, group II: pomegranatepeel extract of 50%, group III: pomegranate peel extract of 75%, group IV: 0.9% NaCl as anegative control, and group V is given mebendazole 0.5% as a positive control. The meanpercentage of dead worms in group I is 39%, in group II 61%, while in group III 82%, but itspotential is lower than mebendazole, which kills 100%. The treatment using pomegranate peelextract of 25%, 50% and 75% respectively has significant differences with p < 0.05 againstnegative control (NC) using a 0.9% NaCl. The research concludes that the pomegranate peelextract has an anthelmintic effect against Ascaris suum females in vitro.Keywords: pomegranate peel extract, anthelmintic effect, in vitro
Effects of Pomegranate Peel (Punica granatum L.) Extract as an Anthelmintic Amelia, Monica; Jasaputra, Diana K; Tjokropranoto, Rita
Journal of Medicine and Health Vol. 1 No. 5 (2017)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (292.015 KB) | DOI: 10.28932/jmh.v1i5.537

Abstract

Helminths infections caused by Soil-Transmitted Helminths (STH) are found in manypeople living in developing countries, especially in rural areas. People often use pomegranate asan anthelmintic. The aim of this research is to find out the effects of pomegranate peel (Punicagranatum L.) as an anthelmintic to female Ascaris suum in vitro. The research on the effects ofpomegranate peel extract has been conducted on 900 female Ascaris suum in vitro. Ascaris suumare divided into 5 groups, group I: pomegranate peel extract of dose 25%, group II: pomegranatepeel extract of 50%, group III: pomegranate peel extract of 75%, group IV: 0.9% NaCl as anegative control, and group V is given mebendazole 0.5% as a positive control. The meanpercentage of dead worms in group I is 39%, in group II 61%, while in group III 82%, but itspotential is lower than mebendazole, which kills 100%. The treatment using pomegranate peelextract of 25%, 50% and 75% respectively has significant differences with p < 0.05 againstnegative control (NC) using a 0.9% NaCl. The research concludes that the pomegranate peelextract has an anthelmintic effect against Ascaris suum females in vitro.Keywords: pomegranate peel extract, anthelmintic effect, in vitro
Co-Authors Diana K Jasaputra, Diana K Monica Amelia, Monica