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All Journal JURNAL GIZI INDONESIA Journal of Nutrition College Media Gizi Mikro Indonesia Jurnal Gizi Klinik Indonesia Kesmas: Jurnal Kesehatan Masyarakat Nasional Darussalam Nutrition Journal Jurnal Gizi Klinik Indonesia Amerta Nutrition Jurnal Aisyah : Jurnal Ilmu Kesehatan JKKI : Jurnal Kedokteran dan Kesehatan Indonesia

Nurmasari Widyastuti

Department Of Nutrition Science, Faculty Of Medicine, Universitas Diponegoro, Semarang, Indonesia

Author-ID : 416708

Biochemistry, Genetics & Molecular Biology Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health Veterinary Other

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Keseimbangan asam-basa tubuh dan kejadian sindrom metabolik pada remaja obesitas Jauharany, Firdananda Fikri; Widyastuti, Nurmasari
Jurnal Gizi Klinik Indonesia Vol 14, No 1 (2017): Juli
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Background: The prevalence of metabolic syndrome increased in young population, indicated by the rise in obesity among children and adolescent. The Western dietary pattern was one of the causes. A Western diet rich in animal protein can produce acid during the metabolic process and may cause an acid-excess in the body (dietary acid load). This process was contributed to acid-base balance through the metabolism of sulfur-containing amino acids (cysteine and methionine) which produce H+ ions as well as lowering the pH.Objective: To examine the association between acid-base balance and components of metabolic syndrome among obese adolescent.Method: A cross-sectional study was conducted on 40 obese adolescents in Semarang high school. We measured Potential Renal Acid Load (PRAL) score and pH urine as an acid-base indicator. MetS are defined â‰¥ 3 following risk factors: waist circumference â‰¥90th percentile, blood pressure â‰¥90th percentile, triglycerides â‰¥110 mg/dl, HDL levels â‰¤40 mg/dl, and fasting blood glucose levels â‰¥110 mg/dl. Normality test used the Shapiro-Wilk test (n <50). The bivariate analysis used Pearson test, Rank-Spearman test, and Chi-Square test. The multivariate analysis used Multivariate Linear Regression analysis of Backward.Results:Â PRAL score was associated with waist circumference (r=0,347; p=0,028), sistolic blood pressure (r=0,590; p=<0,001), diastolic blood pressure (r=0,668; p=<0,001), and triglyceride levels (r=0,362; p=0,022). pH urin was not associated with any risk factors of MetS.Conclusion: High dietary acid load may be a risk factor for the development of MetS.

Sindrom metabolik pada remaja obes: prevalensi dan hubungannya dengan kualitas diet Dieny, Fillah Fithra; Widyastuti, Nurmasari; Fitranti, Deny Yudi
Jurnal Gizi Klinik Indonesia Vol 12, No 1 (2015): Juli
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Background:Â The increasing prevalence of adolescents obesity in the last decade have an impact on the increased prevalence of adolescents metabolic syndrome (MetS). Diet quality is one of the determining factors in the incidence of adolescents obesity, so it can also be a factor for MetS.Objective:Â To analyze the relationship between diet quality and MetS risk factors in obese adolescents.Method:Â A cross-sectional study was conducted on the 57 obese students in 7thÂ and 8thÂ grades of Nasima and Kesatrian Junior High School in Semarang. Blood pressure (BP) and waist circumference (WC) measurements, as well as blood samples for measurement of fasting blood glucose (FBG), triglyceride (TG) and HDL cholesterol (HDL-C), were conducted to determine the number of risk factors experienced by the subject. Diet quality was measured through assessment of food consumption using a food frequency questionnaire (FFQ). Pearson and Spearman's test was used to determine the correlation between diet quality and MetS risk factors.Results:Â The majority of obese adolescents (96.5%) had a low-quality of diet. There were 31.6% subjects experienced pre-metabolic syndrome and 68.4% had MetS, with the prevalence of MetS, was higher in male subjects. The diet quality, variety, adequacy scores and fiber intake of the pre-metabolic syndrome group were higher than MetS group. Variety and adequacy scores had significant negative correlation with TG (r = -0.374, p=0.004; r = -0.357, p=0.006, respectively). There was no significant relationship between diet quality score and the number of MetS risk factors (p=0.538), although they had a negative correlation (r = -0.083).Conclusion:Â Prevalence of pre-metabolic syndrome and MetS was 31.6% and 68.4%. Though there was no significant relationship, diet quality had a negative correlation with the number of MetS risk factors. Variety and adequacy scores had a significant relationship with triglyceride levels.

Asupan lemak jenuh dan serat pada remaja obesitas kaitannya dengan sindrom metabolik Widyastuti, Nurmasari; Dieny, Fillah Fithra; Fitranti, Deny Yudi
Jurnal Gizi Klinik Indonesia Vol 12, No 4 (2016): April
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Background: There is an emerging global increase of metabolic syndrome prevalence due to increasing of obesity. Obesity and metabolic syndrome beginning in childhood progressing into adulthood. Â Dietary saturated fat and fiber intake play a role in etiology in obesity.Objective: This study was to examine the associations between dietary saturated fat intake, fiber intake and components of metabolic syndrome among obese adolescents.Method: A cross-sectional study was conducted to 57 obese students aged 13-15 years old of SMP Nasima and SMP Kesatrian 2 Semarang, based on body mass index for ages. Subjects of this study were collected consecutively. Data were collected through waist circumference and blood pressure measurements, fasting biochemical serum analysis and dietary intake assessment. Â Rank Spearman and Pearson correlation test was used to examine the associations between of dietary saturated fat and fiber intake to components of metabolic syndrome.Results: There were 46 subjects (80,7 %) had metabolic syndrome and 11 subjects (19,3 %) had the pre-metabolic syndrome. There was no association between dietary saturated fat intake and waist circumference, HDL cholesterol, triglyceride, fasting blood glucose levels and blood pressure. Fiber intake was negatively associated with blood triglyceride levels (r = -0.340; p = 0.01).Conclusion: There was no association between dietary saturated fat intake and components of metabolic syndrome. There was an association between dietary fiber intake with blood triglyceride levels. Dietary fiber intake has an important role in lipid metabolism.

Asupan makan, sindrom metabolik, dan status keseimbangan asam-basa pada lansia Widyastuti, Nurmasari; Sulchan, Muhammad; Johan, Andrew
Jurnal Gizi Klinik Indonesia Vol 9, No 4 (2013): April
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Background: Metabolic syndrome prevalence increases with age and obesity. The metabolic syndrome is associated with alterations in renal function. Low urine pH has been described as a renal manifestation of the metabolic syndrome. Urine pH is a simple and inexpensive method for determining acid-base status. Recent studies suggest that acid-base status is associated with dietary intake.Objective: To examine relationship between dietary intake, components of metabolic syndrome and urine pH among the elderly.Method: Subjects of this cross-sectional study consist of 49 elderly that were collected consecutively. Height, weight, waist circumference (WC), dietary intake, blood pressure (BP), fasting blood glucose and urine were obtained. Rank Spearman correlation test was used to examine the correlation of components of metabolic syndrome and dietary intake with urine pH. Mann-Whitney test was used to compare the urine pH of the metabolic syndrome group and the normal group. Chi-Square/fisher test was used to calculate prevalence ratio (PR) of metabolic syndrome components to low urine pH. Multivariate analysis was done by multiple linear regression.Results: The mean urine pH of the metabolic syndrome group was 6,06 and significantly lower than the normal group (6,50). WC was the only component of metabolic syndrome that related to urine pH (r=-0,325; p=0,023). Abdominal obesity significantly increases the risk of low urine pH (RP=1,6; p=0,023; CI=1,005-2,442). Urine pH was negatively associated with protein intake and proportion of protein on diet. In multivariate analysis, WC is the most significant factor that predicted urinary pH.Conclusion: Urine acidification is a characteristic of abdominal obesity and the metabolic syndrome. Protein intake and proportion of protein on diet contribute to urine pH.

Pengaruh pemberian ubi jalar ungu (Ipomoea batatas L.Poir) terhadap kadar superoksida dismutase (SOD) tikus wistar jantan (Rattus Norvegicus) yang dipapar asap rokok Widyanti, Alfreda Sabrina; Ardiaria, Martha; Widyastuti, Nurmasari
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 8, No 1 (2019)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Cigarette smoke exposure is one of the source of free radicals that causes oxidative stress and decreases superoxide dismutase (SOD) level. Purple fleshed sweet potato is a type of food that contains antioxidants to neutralize oxidative stress.Objectives: To study the effect of purple fleshed sweet potato on superoxide dismutase (sod) level on rats exposed to cigarette smoke.Methods: This was a true experimental study with a post-test randomized control group design. The rats were randomized into 4 groups (6 rats in each group). The negative control group (K-) was treated with standard diet; the positive control group (K+) was treated with cigarette smoke exposure and standard diet; the treatment 1 (P1) group was treated with standard diet and purple fleshed sweet potato with the dose of 8 g / 200 g bw/day, and the treatment 2 (P2) group was treated with cigarette smoke exposure and purple fleshed sweet potato with the dose of 8 g /200 g bw/day.Results: There was a significant difference of SOD levels in each group (p=0.00) except between group K- and P1. Giving purple fleshed sweet potatoes increased SOD levels as much as 85.81Â±4.59 (P1). The K+ group had the lowest SOD level 22.34Â±3.98. The SOD level for K- group and P2 group was 82.27Â±4.59 and 67.73Â±6.68 respectively.Conclusion: The highest SOD level is on the treatment 1 group which is administered with purple fleshed sweet potato.

Pengaruh pemberian jus jeruk manis (citrus sinensis.) terhadap nilai VO2 max atlet sepak bola di Gendut Dony Training Camp (GDTC) Salatiga Andani, Sofia Arum; Widyastuti, Nurmasari
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 5, No 2 (2017)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : Endurance is the ability ofÂ the body to perform activities or work for a long time without experiencing fatigue. Based on using of energy systems, endurance is divided into aerobic and anaerobic. Aerobic endurance is measured using VO2max value. Aerobic endurance is supported by the availability of carbohydrates and fats. Intake of carbohydrates as much as 30-60 grams/hour can maintain glucose levels and maintain the level of burning carbohydrates in the body, so it can improve the endurance about 30-60 minutes. Carbohydrate content in 300 ml of sweet orange juice is 54,9 grams that can be used to increase endurance atheletes. Objective : The purpose of this study was to analyze the effect of orange juice on VO2max valueÂ in football athletes. Method : This study was in the field ofÂ experimental design with post test only with controlled group design. Â Subject for these study were tweenty-one football athletes which are match with inclusion criteria in Gendut Dony Training Camp (GDTC) Salatiga. The Subject has given 300 ml orange juice and 300 ml placebo 30 minutes before test. VO2max value was measured by using Balke running test. All datas were analyzed by Independent Sample T-tes. Result : Subject characteristic includes age, weight, height, body mass index (BMI), and total food intake were not showing significant difference (p<0,05), therefore subject were categorized as homogen. Significant difference was showed in average ofÂ VO2max value between the treatment group (43,67Â±2,26) and control group (39,33Â±4,39). Conclusion : Consumption of orange juice 30 minutes before exercising shows a significant impact to increase the VO2max value.

Asupan mikronutrien sebagai faktor risiko kejadian sindrom pramenstruasi pada wanita vegetarian Renata, Maria Dolorosa Sus; Widyastuti, Nurmasari; Nissa, Choirun
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 6, No 2 (2018)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : Inadequate of vitamin B6, magnesium, zinc, and calcium intake and a lower body mass index can lead to Premenstrual syndrome (PMS) in vegetarian woman. The objective of this study was to determine the association between micronutrients intake, nutritional status and PMS among vegetarian women.Objectives : The objective of this study was to determine the association between micronutrients intake, nutritional status and PMS among vegetarian women.Methods : A cross sectional study was conducted to 44 vegetarians women.Subjects of this study were collected consecutively. Dietary intake were measured by Semi Quantitative Food Frequency Questionnaire (SQFFQ). Score of PMS were measured by Shortened Premenstrual Assessment Form (sPAF).Physical activity were measured by International Physical Activity Questionnaire (IPAQ). Score of stress level were measured by International Physical Activity Questionnaire (PSS-10). Data were analyzed by Chi Square test and ratio prevalence to determine the risk factor.Results : There were 54.55% of subject have a moderate PMS level. There were a correlation between vitamin B6 and PMS (p=0.019;RP=2.96;95%CI=0.9-10), magnesium and PMS (p=0.033;RP=3.8;95%CI=0.6-23), zinc and PMS (p=0.002;RP=6.17;95%CI=0.9-39), physical activity and PMS (p=0.033;RP=3.79;95%CI=0.6-23), stress level and PMS(p=0.045;RP=0.39;95%CI=0.1-1.3). There were no correlation between calcium intake and PMS (p=0.211;RP=1.816;95%;CI=0.569-5.794), BMI and PMS (p=0.355;RP=0.753;95 %; CI=1.443).Conclusion : Intake of vitamin B6, magnesium and zinc, physical activity and stress level were correlated to PMS. Calcium intake and BMI were not correlated to PMS.

PENGARUH PEMBERIAN JUS DAUN UBI JALAR (Ipomoea batatas (L.) Lam) TERHADAP KADAR KOLESTEROL TOTAL TIKUS WISTAR JANTAN (Rattus norvegicus) YANG DIBERI PAKAN TINGGI LEMAK Witosari, Nidya; Widyastuti, Nurmasari
Journal of Nutrition College Vol 3, No 4 (2014): Oktober 2014
Publisher : Departemen Ilmu Gizi, Fakultas Kedokteran, Universitas Diponegoro

Latar Belakang: Peningkatan kadar kolesterol total meningkatkan resiko terjadinya penyakit kardiovaskuler. Daun ubi jalar merupakan bahan makanan yang mengandung polifenol, flavonoid, quercetin, tanin, dan serat yang efektif menurunkan kadar kolesterol total. Penelitian ini bertujuan untuk menganalisis pengaruh pemberian jus daun ubi jalar terhadap kadar kolesterol total serum tikus yang diberi pakan tinggi lemak.Metoda: Penelitian eksperimental dengan pre-post test dilakukan pada 12 tikus wistar jantan (Rattus norvegicus) yang diberi pakan tinggi lemak yang dikelompokkan menjadi 2 kelompok yaitu: 1 kelompok kontrol dan 1 kelompok yang diberikan jus daun ubi jalar. Dosis berdasarkan kadar quercetin yaitu sebesar 2 mg/kgBB. Kadar quercetin jus daun ubi jalar dianalisis sehingga diperoleh dosis sebesar 0.006 ml/gBB tikus/ hari. Jus daun ubi jalar diberikan selama 14 hari dengan cara di sonde. Kadar kolesterol total serum ditentukan melalui metode CHOD-PAP. Data dianalisis dengan paired t-test, independent t-test, uji Willcoxon, dan uji Mann-Whitney. Hasil: Pemberian jus daun ubi jalar mampu menurunkan kadar kolesterol total serum. Rerata penurunan kadar kolesterol total sebesar 6,22 mg/dl. Rerata kadar kolesterol total kelompok kontrol mengalami peningkatan sebesar 3,54 mg/dl. Tidak ada perbedaan yang signifikan (p>0.05) pada perubahan kadar kolesterol totalKesimpulan: Pemberian jus daun ubi jalar sebesar 0.006 ml/gBB/hari selama 14 hari dapat menurunkan kadar serum kolesterol total pada tikus yang diberi pakan tinggi lemak

HUBUNGAN ASUPAN PROTEIN DENGAN OBESITAS PADA REMAJA Suryandari, Beti Dwi; Widyastuti, Nurmasari
Journal of Nutrition College Vol 4, No 4 (2015): Oktober 2015
Publisher : Departemen Ilmu Gizi, Fakultas Kedokteran, Universitas Diponegoro

Latar Belakang : Obesitas merupakan masalah kesehatan kompleks. Remaja yang mengalami obesitas dapat memiliki peningkatan risiko kematian saat dewasa. Kelebihan asupan makan merupakan salah satu faktorÂ penyebab terjadinya obesitas. Protein merupakan jenis makronutrien yang berkaitan dengan kejadian obesitas. Jenis protein juga berhubungan dengan obesitas. Penelitian terbaru menunjukkan bahwa terdapat hubungan asupan protein hewani dan asupan protein nabati dengan obesitas.Â Tujuan : Mengetahui hubungan antara asupan protein dengan obesitas pada remaja.Metode : Penelitian ini dilaksanakan di SMP Kesatrian 2 Semarang pada bulan Juni 2015.Desain penelitian cross-sectional dengan subyek 49 remaja usia 12-14 tahun dipilih dengan metode simple random sampling. Data yang diambil adalah berat badan, tinggi badan dan asupan protein. Analisis bivariat dengan uji rank Spearman dan Pearson.Hasil : Terdapat 28,6% remaja mengalami obesitas. Hasil penelitian menunjukkan 55,1% subjek memiliki asupan protein cukup, 65,3%Â subjek mengkonsumsi protein nabati melebihi kebutuhan dan 91,8% subjek mengkonsumsi protein hewani melebihi kebutuhan. Terdapat hubungan signifikan antara asupan protein total (r=0.732 p=0.000), protein hewani (r=0.735p=0.000) dan asupan protein nabati (r=-0.319 p=0.026) dengan IMT.Kesimpulan : Asupan protein total, protein hewani, protein nabati memiliki hubungan signifikan dengan IMT.

PENGARUH PEMBERIAN JUS SEMANGKA KUNING (CITRULUS LANATUS) TERHADAP KONSUMSI OKSIGEN MAKSIMAL (VO2MAX) PADA ATLET SEPAK BOLA Setiawan, Muhamad Irwan; Widyastuti, Nurmasari
Journal of Nutrition College Vol 5, No 2 (2016): April
Publisher : Departemen Ilmu Gizi, Fakultas Kedokteran, Universitas Diponegoro

Latar belakang : Penurunan performa latihan sering dialami oleh atlet sepak bola Indonesia. Salah satu indikator performa adalah kebugaran jasmani yang dapat diukur dengan nilai konsumsi oksigen maksimal VO2max. Semangka memiliki kandungan sitrulin, suatu asam amino yang dapat dirubah menjadi nitrit oksida (NO) pada mekanisme penghasilan VO2max. Tujuan : Penelitian ini bertujuan untuk mengetahui pengaruh pemberian jus semangka kuning terhadap VO2max pada atlet sepak bola.Metode: Desain kuasi eksperimental dengan pendekatan pretestâ€“post test control group design pada 16 atlet Klub Sepak Bola PPLP Jawa tengah usia 15-17 tahun bulan November 2015. Kelompok perlakuan diberikan jus semangka kuning 750 ml, sedangkan kontrol 750 ml sirup sukrosa. Intervensi diberikan selama 7 hari. Metode MFT (Multistage Fitness Test) dilakukan untuk mengukur VO2max sehari sebelum dan sesudah intervensi.Â Â Hasil: Terdapat perbedaan signifikan VO2max antara kedua kelompok (p<0.05), dimana VO2max 54.3Â±1.88 ml/kg/menit pada kelompok perlakuan dan 52.1Â±1.78 ml/kg/menit pada kelompok kontrol. Peningkatan VO2max pada kelompok perlakuan (2.27Â±1.09 ml/kg/menit) lebih tinggi dibanding kontrol (1.92Â±3.6 ml/kg/menit). Namun, secara klinis VO2max kedua kelompok pada sebelum dan sesudah intervensi masih dalam kategori sangat baik (>51.6 ml/kg/menit). Kesimpulan : Pemberian jus semangka kuning dapat meningkatkan VO2max pada atlet sepak bola.

Co-Authors A Fahmy Arif Tsani Abyyudha, Dany Adriyan Pramono Agita, Viony Vira Ahmad Syauqy Andani, Sofia Arum Andrew Johan Ani Margawati Anjani, Gemala Anjarsari Retno Utami, Anjarsari Retno Arifani, Rochanisa Sita Aristanti, Aprilia Aryu Candra Astuti, Anak Agung Ayu Fuji Dwi Atika Putri Widia Anggraeni Ayu Rahadiyanti Beti Dwi Suryandari, Beti Dwi Binar Panunggal Choirun Nissa Choirun Nissa Deny Yudi Fitranti Dewi Kurnia Sandi Dewi Marfu’ah Kurniawati Dewi, Arini Citra Dhea Aghestya Enny Probosari Etika Ratna Noer Etisa Adi Murbawani Fillah Fithra Dieny Hartanti Sandi Wijayanti Hermawan, Febriyanti Jauharany, Firdananda Fikri Junita, Dera Elva Keyasa, Magnalia Morena Ruth Kusumastuti, Evi Legowo, Anang M Lestari, Rahma Wati Dwi Manik, Rifial Ramadhan MARTHA ARDIARIA Monikasari, Monikasari Muhammad Sulchan Muhammad Sulchan Muniroh, Muflihatul Mursid Tri Susilo Nabila, Rumaisha Nidya Witosari Nissa, Choirun Pravita Dewi Suhada Purbosari, Enny Puspasari, Indah Rachma Purwanti Rahma Wati Dwi Lestari Rahmadani, Prita Ady Rani Pramesti Renata, Maria Dolorosa Sus Rifial Ramadhan Manik Rika Purwani, Rika Rujiantina, Ahaddini Septian Sahara, Mailina Prima Septamarini, Risna Galuh Setiawan, Muhamad Irwan Siringoringo, Ester Theresia Tsani, A Fahmy Arif Wanty, Wanty Wardana, Ruliansyah Kusuma Widya Destikasari Widyanti, Alfreda Sabrina wulandari, Retno Tri Zana Fitriana Octavia

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