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IETJE WIENTARSIH
Institut Pertanian Bogor
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Earth & Planetary Sciences Energy Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Veterinary

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Journal : Jurnal%20Ilmu%20dan%20Teknologi%20Kayu%20Tropis

 1 
Stabilitas Fisikokimia dan Sifat Antipenuaan Kulit Formula Krim Berbahan Aktif Alami (Physicochemical stabilities and Skin Antiaging Properties of Bioaktive-based Cream Formulas) Rita K Sari; Nyoman J Wistara; Deded S Nawawi; Nopen Meisaroh; Ietje Wientarsih; D R Agungpriyono; L N Sutardi; Mawar Subangkit; Vetnizah Juniantito
Jurnal Ilmu dan Teknologi Kayu Tropis Vol 15, No 1 (2017): Jurnal Ilmu dan Teknologi Kayu Tropis
Publisher : Masyarakat Peneliti Kayu Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (525.345 KB) | DOI: 10.51850/jitkt.v15i1.366

Abstract

 The purpose of this study was  to analyze the physicochemical stabilities  and in vivo antiaging  properties of the cream formulas of F1, F2, and F3 which contained the active compound of 0.1% 0.18, and 0.36%, respectively. The active compound was the combination of  ethyl acetate fraction of  Toona sinensis, Centella asiatica, and Acacia mangium  leaf (1:2:1). For physicochemical stability tests (color, odor, acidity, and antioxidant activity), the creams were stored for 21 days in the refrigerator, room temperature,   and extreme temperature (±40 ⁰C). For in vivo antiaging test,  the mice skin  were smeared with cream and UV irradiated for 15 minutes per day. After two and four weeks, the mice skins were  biopsied. The results showed that the physicochemical properties of creams stored in the refrigerator were  stable. The storage of creams at room and  extreme temperature decreased the physicochemical properties.  The application of cream formulas on mice skin after two to four weeks were able to increase the thickness of epidermis, but has not been able to increase the collagen skin of mice.Keywords: Acacia mangium, Centella asiatica, ethyl acetate fraction of leaf, physicochemical and antiaging properties of cream, Toona sinensis
Co-Authors Ahmad Kurniawan Andriyanto . ANGGARA ALDOBRATA April Hari Wardhana April Hari Wardhana April Hari Wardhana Aswin Rahadian Aulia Andi Mustika Aulia Andi Mustika Aulia Andi Mustika Aulia Andi Mustika Bambang Pontjo Priosoeryanto Bayu Febram Bayu Febram Bayu Febram Prasetyo Bayu Febran Prasetyo Chandra Utami Wirawati D R Agungpriyono Deded Sarip Nawawi Denny Widaya Lukman Dian Firnanda Dodi Darmakusuma Dodi Darmakusumah Dondhin Sajuthi Dondin Sajuthi Eko Agus Srihanto Erni H Purwaningsih Erni H Purwaningsih Esti Dhamayanti Eva Harlina Farra Sasmita Fikri Hanifah Gunanati Soedjono Hr. Sjarif, Sulistyantie Huda Shalahudin Darusman I Nyoman Jaya Wistara I Putu Kompiang Ikrar Trisnaning Hardi Utami Indra Bachtiar Irma Maulani Hamzah Istifharany Wahyudina L N Sutardi Lina Elfita Lina Noviyanti Sutardi M. Yanuar J. Purwanto Maulani Hamzah, Irma Meilisa Lidya Margarita Min Rahminiwati Miranti Fardesiana Putri Mirnawati Bachrum Sudarwanto Mirnawati Sudarwanto Muhammad Bintang Nopen Meisaroh Nova P. Sulistyawati R. Harry Soehartono Rahmawati Januar Rastina Rastina RINI MADYASTUTI Rita Kartika Sari Rizal Arifin Akbari Ros Sumarny Sajuthi, Dondhin Setyo Widodo Setyo Widodo Subangkit, Mawar Sulistyantie Hr. Sjarif Sus Derthi Widhyari TATI NURHAYATI Tika Aryanti Tyas Ayu Lestari Upik Kesumawati Hadi Vetnizah Juniantito Wiwin Winarsih