Eric Edwin Yuliantara
Department Of Obstetrics And Gynaecology, Faculty Of Medicine, Universitas Sebelas Maret/Dr. Moewardi General Hospital, Surakarta

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Hubungan Multi Paritas dengan Tingkat Kejadian Kanker Serviks di RSUD Dr Moewardi Totok Siswanto; Eric Edwin Yuliantara; Lilik Wijayanti
Nexus Kedokteran Klinik Vol 3, No 1 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Cervical cancer is one of the most common cancer found in women and ranks second all cancers in women in the world. Multi parity thought to be one of the risk factors for cervical cancer. Hormonal and anatomical changes that occur in multi parity may increase the risk of cervical cancer by a variety of mechanisms. The purpose of this study was to determine the incidence rates of cervical cancer are associated with multi parity status. Methods: The type of research is an case-control. The samples in this study were patients with cervical cancer and other gynecological diseases with a total sample of 60 people. Measuring instrument used was a questionnaire, and then performed the data analysis with multiple logistic regression analysis. Result: Found a statistically significant association between the multi-parity status with the incidence of cervical cancer. People with multi-parity status have an increased risk for cervical cancer was 8.986 times greater than women with non-multi-parity status (p = 0.003, OR = 8.986). Conclusion: Based on research of woman with multi parity status will have the risk of having cervical cancer by 8,986 times compared to women with non-multi-parity status. Key Words: multi parity, cervical cancer
Hubungan Tingkat Pengetahuan Dismenorea terhadap Perilaku Penanganan Dismenorea pada Mahasiswi Fakultas Kedokteran UNS Surakarta Sugiantoro, Muhammad Iqbal; Raden, Abkar; Edwin, Erick
Nexus Kedokteran Komunitas Vol 1, No 2 (2012): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Dysmenorrhea occured in 72,4% women where 15,4% of them suffered severe dysmenorrhea that may hinder the person doing activity or work. Behavioral treatment of dysmenorrhea can help the person to reduce the symptoms that may hinder or inhibit a person’s activity. Knowledge is an important determinant for the individual to behave. This study aims to know the relationship between knowledge level of dysmenorrhea to behavioral treatment of dysmenorrhea. Methods: This study was analytical observational with cross sectional approach, and used primary data. These sample were first, second, and third grade students of Medicine Faculty of Sebelas Maret University who suffered dysmenorrhea. Sixty four Samples taken by purpossive random sampling methods. All samples were given questionnaire to measure the knowledge level and behavioral treatment of dysmenorrhea. Data analysis using Chi Square test. Results: The result showed 53% sample’s kowledge level of dysmenorrhea were good and 47% were less. From behavioral treatment of dysmenorrhea sample’s ,we get 62% samples treated with his own and 38% went to doctor. From the analysis Chi Square test p= 0,001 and OR= 3,04. Conclusions: Based on result of the study can be concluded that there is a relationship between knowledge level of dysmenorrhea to behavioral treatment of dysmenorrhea. Student with good knowledge level of dysmenorrhea has 3,04 chance to go to the doctor treating dysmenorrhea. Keywords: Knowledge Level of Dysmenorrhea, Behavioral Treatment of                            Dysmenorrhea  
Hubungan Tingkat Pengetahuan Mengenai Zat Besi Dengan Tingkat Kepatuhan Mengkonsumsi Tablet Besi Pada Ibu Hamil Di Puskesmas Sibela Mojosongo Surakarta Septiani, Dwi Tiara; Edwin, Erick; Sukilarso, Bambang
Nexus Kedokteran Komunitas Vol 2, No 2 (2013): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Anemia in pregnant women increases the frequency of complications of pregnancy and childbirth. Anemia due to iron deficiency is a major cause of anemia in pregnant women compared with deficiencies of other nutrients. Iron anemia prevention programs, especially for pregnant women has been done through the provision of iron for free through the health center or posyandu. However, because of the limited knowledge of most of the pregnant women then this program seem to run slow. This study aims to demonstrate a link between the level of knowledge about the level of compliance with the iron taking iron tablets. Methods: This study was an observational analytic cross-sectional approach. Subjects were pregnant women Sibela Mojosongo the Surakarta Health Center. Sample of pregnant women who took iron tablets. Samples were taken by purposive sampling. The data collection technique using a questionnaire concerning the knowledge level of iron, the level of knowledge questionnaires and scales consuming iron tablets LMMPI inventory. Data score of knowledge about iron with Compliance Consuming Iron Tablets in pregnant women were analyzed with chi square test. Results: Obtained 30 samples of pregnant women. The results of chi-square analysis showed that there is a positive relationship between the level of knowledge regarding iron with adherence consuming iron tablets at the health center Mojosongo Sibela Surakarta. that patients with a high level of knowledge has compliance 35 times higher than those knowledgeable with p = <0.001 (OR = 35; 95% Cl 2.977 411.466 sd). Conclusions: Based on this study it can be concluded that there is a correlation between the level of knowledge about the level of compliance with the iron taking iron tablets to pregnant women. The higher the mothers level of knowledge of the iron, the higher the level of compliance in consuming iron tablets Keywords: Pregnant women, knowledge of iron, compliance consuming iron tablets
Hubungan Antara Stres Psikologis Dan Olahraga Terhadap Terjadinya Dismenore Primer Pada Mahasiswi Fakultas Kedokteran Universitas Sebelas Maret Ananda, Mutiara Rizky; Y, Eric Edwin; Wijayanti, Lilik
Nexus Kedokteran Klinik Vol 3, No 1 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Abstract

Background: Prevalence of primary dysmenorrhea in the adolescent in Surakarta is 87,7% and 15% of women in Indonesia complained that their activity were interrupted due to dysmenorrhea. Psychological stress and irregular sports allegedly have connection in increase the incidence of primary dysmenorrhea. This research aims to know the relation between psychological stress and exercise against the occurrence of primary dysmenorrhea. Methods: This study is analytical observational with cross sectional approach, and using primary data. This study using medical student of 2010, 2011, 2012 at Sebelas Maret University as sample, taken by simple random sampling methods about 62 samples. Data analysis using Chi Square test and binary logistic regression. Results: Result of data analysis using Chi Square test shows p value for the relationship of psychological stress with primary dysmenorrhea is 0,013 whereas p value of relations sports with primary dysmenorrhea is 0,009. For the results of the analysis data using binary logistic regression found that psychological stress has OR = 0,352 whereas exercise has OR =  3,808. Conclusions: Based on result of the study can be concluded that there is a relationship between psychological stress and exercise against the occurrence of primary dysmenorrhea in the medical student of Sebelas Maret University Surakarta. Keywords: Psychological Stress, Exercise, Primary Dysmenorrhea. 
Hubungan Multi Paritas dengan Tingkat Kejadian Kanker Serviks di RSUD Dr Moewardi Siswanto, Totok; Yuliantara, Eric Edwin; Wijayanti, Lilik
Nexus Kedokteran Klinik Vol 3, No 1 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Abstract

Background: Cervical cancer is one of the most common cancer found in women and ranks second all cancers in women in the world. Multi parity thought to be one of the risk factors for cervical cancer. Hormonal and anatomical changes that occur in multi parity may increase the risk of cervical cancer by a variety of mechanisms. The purpose of this study was to determine the incidence rates of cervical cancer are associated with multi parity status. Methods: The type of research is an case-control. The samples in this study were patients with cervical cancer and other gynecological diseases with a total sample of 60 people. Measuring instrument used was a questionnaire, and then performed the data analysis with multiple logistic regression analysis. Result: Found a statistically significant association between the multi-parity status with the incidence of cervical cancer. People with multi-parity status have an increased risk for cervical cancer was 8.986 times greater than women with non-multi-parity status (p = 0.003, OR = 8.986). Conclusion: Based on research of  woman with multi parity status will have the risk of having cervical cancer by 8,986 times compared to women with non-multi-parity status. Key Words: multi parity, cervical cancer 
Hubungan antara Anemia dan Kejadian Inersia Uteri di RSUD Dr.Moewardi Sari, Dhyani Rahma; Edwin, Eric; Damayanti, Kusmadewi Eka
Nexus Kedokteran Klinik Vol 3, No 2 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Abstract

Background: Anemia is a condition of reduced levels of hemoglobin ( Hb ) which  leads to impaired maternal oxygen delivery to form energy in the uterine muscles to make contractions in labor. This research aims to investigate the relation between anemia and prevalence of uterine inertia. Methods: This was an analitic-observational cross sectional study using medical record data from 1 January 2012  – 30 May 2012 . A sample of 112 subjects was selected  from patiens who gave birth with anemia in Moewardi hospital. Sample was conducted in total sampling. Data were analyzed using Chi-Square test. The difference seen from the result by Risk Ratio ( RR ), while the significance of the result seen by the value of            p ( p < 0,05 ). Results: Analysis of Chi-Square test showed a statistically significant relationship between anemia and the prevalence  of  uterine inertia. The result obtained from the analysis was p = 0,001( p < 0,05 ). Conclusions: There is statistically significant relatonship between maternal anemia with prevalence of uterine inertia in Moewardi hospital during period the first of January 2012  – the thirtith of  May 2012  . Keywords: anemia, labour, uterine inertia.  
Recombinant vascular endothelial growth factor 121 decreases vascular cell adhesion molecule-1 in murine pre-eclampsia model placenta Sulistyowati, Sri; Sondakh, John Arianto; Yuliantara, Eric Edwin; Respati, Supriyadi Hari; Soetrisno, Soetrisno
Universa Medicina Vol 35, No 3 (2016)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2016.v35.192-198

Abstract

BackgroundPreeclampsia is one of the major contributors to maternal and fetal morbidity and mortality. Imbalance of soluble Fms-like tyrosine kinase (sFlt-1) as anti-angiogenic factor and vascular endothelial growth factor (VEGF) as pro-angiogenic factor plays a role in the pathogenesis of preeclampsia. Endothelial dysfunction in preeclampsia causes vascular cell adhesion molecule-1 (VCAM-1) to be expressed on its surface. This study aims to evaluate the effect of recombinant VEGF-121 on VCAM-1 expression in the placenta of a murine preeclampsia model. Methods An experimental analytical study conducted from February until March 2016 in the Biomedical Laboratory, Faculty of Veterinary Medicine, Airlangga University. The study sample consisted of 30 pregnant mice, divided into three groups, i.e. 10 normal pregnant mice, 10 mice with preeclampsia model and 10 mice with preeclampsia model and recombinant VEGF-121 therapy. All animals were subjected to immunohistochemical examination of VCAM-1 expression in their placentas. The results were assessed semiquantitatively according to a modified Remmele method. Data analysis was done using one-way ANOVA and Tukey’s multiple comparisons method. ResultsMean VCAM-1 expression in normal (0.97 ± 0.54%) murine placentas, compared with placentas (2.94 ± 0.96%) of murine preeclampsia models (p=0.000), while mean VCAM-1 expression in placentas of murine preeclampsia models with VEGF intervention was 2.14 ± 0.68% (p=0.030).Conclusion Recombinant VEGF-121 can reduce VCAM-1 expression in placentas of murine preeclampsia models. The present study has shown the potential benefits of VEGF therapy, justifying serious consideration of this therapeutic approach for use in women with preeclampsia.
Hubungan Tingkat Pengetahuan Mengenai Zat Besi Dengan Tingkat Kepatuhan Mengkonsumsi Tablet Besi Pada Ibu Hamil Di Puskesmas Sibela Mojosongo Surakarta Dwi Tiara Septiani; Erick Edwin; Bambang Sukilarso
Nexus Kedokteran Komunitas Vol 2, No 2 (2013): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.115 KB)

Abstract

Background: Anemia in pregnant women increases the frequency of complications of pregnancy and childbirth. Anemia due to iron deficiency is a major cause of anemia in pregnant women compared with deficiencies of other nutrients. Iron anemia prevention programs, especially for pregnant women has been done through the provision of iron for free through the health center or posyandu. However, because of the limited knowledge of most of the pregnant women then this program seem to run slow. This study aims to demonstrate a link between the level of knowledge about the level of compliance with the iron taking iron tablets. Methods: This study was an observational analytic cross-sectional approach. Subjects were pregnant women Sibela Mojosongo the Surakarta Health Center. Sample of pregnant women who took iron tablets. Samples were taken by purposive sampling. The data collection technique using a questionnaire concerning the knowledge level of iron, the level of knowledge questionnaires and scales consuming iron tablets LMMPI inventory. Data score of knowledge about iron with Compliance Consuming Iron Tablets in pregnant women were analyzed with chi square test. Results: Obtained 30 samples of pregnant women. The results of chi-square analysis showed that there is a positive relationship between the level of knowledge regarding iron with adherence consuming iron tablets at the health center Mojosongo Sibela Surakarta. that patients with a high level of knowledge has compliance 35 times higher than those knowledgeable with p = <0.001 (OR = 35; 95% Cl 2.977 411.466 sd). Conclusions: Based on this study it can be concluded that there is a correlation between the level of knowledge about the level of compliance with the iron taking iron tablets to pregnant women. The higher the mother's level of knowledge of the iron, the higher the level of compliance in consuming iron tablets Keywords: Pregnant women, knowledge of iron, compliance consuming iron tablets
Hubungan Antara Stres Psikologis Dan Olahraga Terhadap Terjadinya Dismenore Primer Pada Mahasiswi Fakultas Kedokteran Universitas Sebelas Maret Mutiara Rizky Ananda; Eric Edwin Y; Lilik Wijayanti
Nexus Kedokteran Klinik Vol 3, No 1 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Abstract

Background: Prevalence of primary dysmenorrhea in the adolescent in Surakarta is 87,7% and 15% of women in Indonesia complained that their activity were interrupted due to dysmenorrhea. Psychological stress and irregular sports allegedly have connection in increase the incidence of primary dysmenorrhea. This research aims to know the relation between psychological stress and exercise against the occurrence of primary dysmenorrhea. Methods: This study is analytical observational with cross sectional approach, and using primary data. This study using medical student of 2010, 2011, 2012 at Sebelas Maret University as sample, taken by simple random sampling methods about 62 samples. Data analysis using Chi Square test and binary logistic regression. Results: Result of data analysis using Chi Square test shows p value for the relationship of psychological stress with primary dysmenorrhea is 0,013 whereas p value of relations sports with primary dysmenorrhea is 0,009. For the results of the analysis data using binary logistic regression found that psychological stress has OR = 0,352 whereas exercise has OR = 3,808. Conclusions: Based on result of the study can be concluded that there is a relationship between psychological stress and exercise against the occurrence of primary dysmenorrhea in the medical student of Sebelas Maret University Surakarta. Keywords: Psychological Stress, Exercise, Primary Dysmenorrhea.
Hubungan antara Anemia dan Kejadian Inersia Uteri di RSUD Dr.Moewardi Dhyani Rahma Sari; Eric Edwin; Kusmadewi Eka Damayanti
Nexus Kedokteran Klinik Vol 3, No 2 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Abstract

Background: Anemia is a condition of reduced levels of hemoglobin ( Hb ) which leads to impaired maternal oxygen delivery to form energy in the uterine muscles to make contractions in labor. This research aims to investigate the relation between anemia and prevalence of uterine inertia. Methods: This was an analitic-observational cross sectional study using medical record data from 1 January 2012 30 May 2012 . A sample of 112 subjects was selected from patiens who gave birth with anemia in Moewardi hospital. Sample was conducted in total sampling. Data were analyzed using Chi-Square test. The difference seen from the result by Risk Ratio ( RR ), while the significance of the result seen by the value of p ( p < 0,05 ). Results: Analysis of Chi-Square test showed a statistically significant relationship between anemia and the prevalence of uterine inertia. The result obtained from the analysis was p = 0,001( p < 0,05 ). Conclusions: There is statistically significant relatonship between maternal anemia with prevalence of uterine inertia in Moewardi hospital during period the first of January 2012 the thirtith of May 2012 . Keywords: anemia, labour, uterine inertia.