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All Journal SONDE (Sound of Dentistry) Interdental Jurnal Kedokteran Gigi (IJKG) MDJ (Makassar Dental Journal)
Nugrahini, Sintha
Departemen Gigi Dan Mulut, Fakultas Kedokteran, Universitas Palangka Raya, Palangka Raya, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Public Health

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AKTIVITAS ANTIFUNGI EKSTRAK DAUN PEPAYA TERHADAP Candida Albicans PADA BASIS GIGI TIRUAN LEPASAN Nugrahini, Sintha; Nurlitasari, Dewi Farida
Interdental: Jurnal Kedokteran Gigi Vol 15 No 1 (2019): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v15i1.337

Abstract

Plaque accumulation on removable denture mayinduce Denture Stomatitis (DS). Candida albicans is the main microorganism that causes DS. To prevent DS, dentures need to be cleaned. The simplest denture cleaning method is immersion using chemicals. Papaya leaf (Carica papaya) contain antifungi substance, could be used as denture cleanser. The aim of this study wasto prove the effectivity of papaya leaf extract todecreasing the number of Candida albicans colonies on acrylic resin plates and thermoplastic nylon. This study was pretest-posttest with control group design, 32 samples (16 acrylic resin plates, 16 thermoplastic nylon plates) were divided into 4 groups: immersion using aquadest, fittydent®, papaya leaf extract 10% and 40%. Paired T-test showed the means of Candida albicans number on acrylic resin plates after immersion of aquadest, fittydent®, papaya leaf extract 10% and 40% were 0.75+2.98 CFU/ml, 82.5+1.29, 53.5+3.31 CFU/ml, 81.5+2.38 CFU/ml. The means of Candida albicans number on thermoplastic nylon after immersion of aquadest, fittydent®, papaya leaf extract 10% and 40% were 0.5+1.73 CFU/ml, 82.25+2.21 CFU/ml, 70.25+3.3 CFU/ml, 80.50+3.69 CFU/ml. Oneway ANOVA test showed no significant differences number of Candida albicans colonies (p >0.05) after immersion using fittydent® and papaya leaf extract 40% on both plates (100% Candida albicans cells died after immersion). The decrease percentage shown in the immersion of papaya leaf extract 10% group (66.67% on acrylic resin plates and 87.8% on thermoplastic nylon).This study concluded that papaya leaf extract was effective in decreasing the number of Candida albicans colonies on acrylic resin plates and thermoplastic nylon.
PENINGKATAN AKTIVITAS SEL EPITEL PADA KASUS DENTURE STOMATITIS OLEH GEL Epigallocatechin gallate 0,5% Nugrahini, Sintha
Interdental: Jurnal Kedokteran Gigi Vol 14 No 2 (2018): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v14i2.375

Abstract

Complete denture wearing patients are often associated with the presence of denture stomatitis. Poor-fitting dentures may increase mucosal trauma. It cause pressure on the mucosa and create a mechanical irritation. Epigallocatechin gallate(EGCG), is a flavonoid class of polyphenols antioxidant that have been widely researched, proven to have anti-inflammatory effects and may improve wound healing. The objective of this study was to prove the potential role of EGCG promoting reepithelialization of oral mucosa woundhealing.The study was a randomized Post Test Only ControlGroup Design experimental study. 32 male rats (Rattus norvegicus) were divided into 2 treatment groups. The controlgroup were given placebo gel administration (CMC-Na) for 3 days, and the treatment groups were given EGCG Gel 0.5% for 3 days. On the 6th day, mice were euthanized for tissue sampling and histological preparations, made by HE stainning. The data were analyzed using the Independent t-Test.The mean of epithelial cleft oftreatment group (549.25 ± 217.094 µm) was lower than the controlgroup (1417.25 ± 180.572 µm), it was statistically different.EGCG Gel 0.5% increaseproduction of TransformingGrowth Factor-beta 1 (TGF-β1) to stimulate migration and adhesion of epithelial cell.Thus, it is concluded that EGCG gel 0.5% enhance reepithelialization on mucosa wound healingof Denture Stomatitis.
JUMLAH KOLONI CANDIDA ALBICANS PADA PLAT RESIN AKRILIK HEAT CURED SETELAH DILAKUKAN PERENDAMAN EKSTRAK DAUN KEMANGI (OCIMUM BASSILICUM LINN) 50% Ayu Wirayuni, Kadek; Nugrahini, Sintha
Interdental: Jurnal Kedokteran Gigi Vol 16 No 2 (2020): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v16i2.1126

Abstract

Accumulation of plaque and food scraps on an acrylic resin base will increase bacterial colonies and C. albicans which will cause denture stomatitis. Maintenance of denture hygiene using mechanical, chemical and combination of two methods. Basil leaf extract contain essential oils which are important in fight against resistant C. albicans biofilms. The purpose of this study was to determine the comparison of C. albicans colonies after cleaning various denture cleaning methods. The method of this study is used an experimental method, the study design is posttest only with control group design. Sample size of heat-cured acrylic resin plate is 40x12x3mm. this study use Kruskall-Wallis test and Mann-Whitney test as data analysis for comparison tests between groups (non-parametric test). The results showed that there were significant differences between the various cleansing methods used in reducing C. albicans colonies. The compotition of flavonoids basil leaf extract is anti-microbial which can prevent the entry of fungi that harm the body.
The Discoloration of Heat Cured Resin Acrylic Base After Immersed in Disinfectant Solution Sintha - Nugrahini
SONDE (Sound of Dentistry) Vol. 5 No. 1 (2020): SONDE (Sound of Dentistry)
Publisher : Maranatha Christian University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/sod.v5i1.2278

Abstract

Acrylic resin dentures are a type of denture that is often used. At present the use of disinfectants to clean dentures from microorganisms, such as sodium hypochlorite and green betle leaves. Sodium hypochlorite contains chlorine, and green betle leaf extract contains tannins that containable to provide color changes in artificial teeth. The purpose of this study was to study the change in color on the hot polymerization acrylic plate after soaking with sodium hypochlorite solution and green betle leaf extract (Piper betle Linn). This study was a pre-post test control group design, the sample was heat-cured resin acrylic base plate and divided into 3 treatment groups: a group immersed in sodium hypochlorite, extract of green betel leaf and control group with aquades. The discoloration measurement was using Spectrophotometer. The sample was immersed for 15 days. Data were analyzed by paired T-test, followed by One way Anova and LSD. The results showed that there were significant color changes in the 2 treatment groups, while the control group was not significant. The mean of discoloration after immersion with Sodium Hypochlorite was 0.668 + 0.018, green betle leaf extract 30% was 0.625 + 0.024, and aquades was 0.534 + 0.0224. Color changes on heat-cured resin acrylic base plate occur by the presence of chlorine in sodium hypochlorite and tannin contained in the green betel leaf extract. This research concluded that immersion of heat-cured resin acrylic plate in sodium hypochlorite solution and 30% betle leaf extract may cause discoloration.
AKTIVITAS ANTIFUNGI EKSTRAK DAUN PEPAYA TERHADAP Candida Albicans PADA BASIS GIGI TIRUAN LEPASAN Sintha Nugrahini; Dewi Farida Nurlitasari
Interdental: Jurnal Kedokteran Gigi Vol. 15 No. 1 (2019): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v15i1.337

Abstract

Plaque accumulation on removable denture mayinduce Denture Stomatitis (DS). Candida albicans is the main microorganism that causes DS. To prevent DS, dentures need to be cleaned. The simplest denture cleaning method is immersion using chemicals. Papaya leaf (Carica papaya) contain antifungi substance, could be used as denture cleanser. The aim of this study wasto prove the effectivity of papaya leaf extract todecreasing the number of Candida albicans colonies on acrylic resin plates and thermoplastic nylon. This study was pretest-posttest with control group design, 32 samples (16 acrylic resin plates, 16 thermoplastic nylon plates) were divided into 4 groups: immersion using aquadest, fittydent®, papaya leaf extract 10% and 40%. Paired T-test showed the means of Candida albicans number on acrylic resin plates after immersion of aquadest, fittydent®, papaya leaf extract 10% and 40% were 0.75+2.98 CFU/ml, 82.5+1.29, 53.5+3.31 CFU/ml, 81.5+2.38 CFU/ml. The means of Candida albicans number on thermoplastic nylon after immersion of aquadest, fittydent®, papaya leaf extract 10% and 40% were 0.5+1.73 CFU/ml, 82.25+2.21 CFU/ml, 70.25+3.3 CFU/ml, 80.50+3.69 CFU/ml. Oneway ANOVA test showed no significant differences number of Candida albicans colonies (p >0.05) after immersion using fittydent® and papaya leaf extract 40% on both plates (100% Candida albicans cells died after immersion). The decrease percentage shown in the immersion of papaya leaf extract 10% group (66.67% on acrylic resin plates and 87.8% on thermoplastic nylon).This study concluded that papaya leaf extract was effective in decreasing the number of Candida albicans colonies on acrylic resin plates and thermoplastic nylon.
PENINGKATAN AKTIVITAS SEL EPITEL PADA KASUS DENTURE STOMATITIS OLEH GEL Epigallocatechin gallate 0,5% Sintha Nugrahini
Interdental: Jurnal Kedokteran Gigi Vol. 14 No. 2 (2018): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Faculty of Dentistry, Mahasaraswati Denpasar University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v14i2.375

Abstract

Complete denture wearing patients are often associated with the presence of denture stomatitis. Poor-fitting dentures may increase mucosal trauma. It cause pressure on the mucosa and create a mechanical irritation. Epigallocatechin gallate(EGCG), is a flavonoid class of polyphenols antioxidant that have been widely researched, proven to have anti-inflammatory effects and may improve wound healing. The objective of this study was to prove the potential role of EGCG promoting reepithelialization of oral mucosa woundhealing.The study was a randomized Post Test Only ControlGroup Design experimental study. 32 male rats (Rattus norvegicus) were divided into 2 treatment groups. The controlgroup were given placebo gel administration (CMC-Na) for 3 days, and the treatment groups were given EGCG Gel 0.5% for 3 days. On the 6th day, mice were euthanized for tissue sampling and histological preparations, made by HE stainning. The data were analyzed using the Independent t-Test.The mean of epithelial cleft oftreatment group (549.25 ± 217.094 µm) was lower than the controlgroup (1417.25 ± 180.572 µm), it was statistically different.EGCG Gel 0.5% increaseproduction of TransformingGrowth Factor-beta 1 (TGF-β1) to stimulate migration and adhesion of epithelial cell.Thus, it is concluded that EGCG gel 0.5% enhance reepithelialization on mucosa wound healingof Denture Stomatitis.
NUMBER OF CANDIDA ALBICANS COLONY ON HEAT CURED ACRYLIC RESIN PLATE AFTER IMMERSION IN BASIL LEAF EXTRACT (OCIMUM BASSILICUM LINN ) 50% SOLUTION : JUMLAH KOLONI CANDIDA ALBICANS PADA PLAT RESIN AKRILIK HEAT CURED SETELAH DILAKUKAN PERENDAMAN EKSTRAK DAUN KEMANGI (OCIMUM BASSILICUM LINN) 50% Kadek Ayu Wirayuni; Sintha Nugrahini
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 16 No. 2 (2020): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v16i2.1126

Abstract

Introduction: Accumulation of plaque and food scraps on an acrylic resin heat cured base will increase bacterial colonies and Candida albicans which will cause denture stomatitis. Maintenance of denture hygiene using mechanical, chemical and combination of two methods. Basil leaf (Ocimum bassilicum Liin) 50% extract contain essential oils which are important to against  Candida albicans biofilms. Purpose: The purpose of this study was to determine the comparison of Candida albicanscolonies after cleaning various denture cleaning methods. Materials and method: The method was an experimental study, and the design was posttest only with control group design. Sample size of heat cured acrylic resin plate is 40x12x3mm. this study use Kruskall-Wallis test and Mann-Whitney test as data analysis for comparison tests between groups (non-parametric test). Result: The results showed that there were significant differences between the various cleansing methods used in reducing Candida albicans colonies. Conclusion: The compotition of flavonoids basil leaf (ocimum Bassilicum Liin) 50% extract is anti-microbial which can prevent the entry of fungi that harm the body.
Observation of dentures using in the community at the dental and oral health service in Petang Village Petang District, Badung Regency, Bali Sintha Nugrahini; Intan Kemala Dewi; Kadek Dwi Dessy Sapitri; I Made Agus Astika
Makassar Dental Journal Vol. 9 No. 2 (2020): Volume 9 No 2 Agustus 2020
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v9i2.331

Abstract

Gigi tiruan diperlukan dalam pemenuhan kesehatan pada umumnya serta kesehatan gigi dan mulut khususnya terutama untuk mempertahankan fungsi kunyah.Tujuan penelitian adalah ingin mengetahui persentase jumlah masyarakat Desa Petang yang menggunakan gigi tiruan untuk menggantikan gigi alami yang telah dicabut. Penelitian ini merupakan penelitian observasi analitik dengan pendekatan cross sectional. Jumlah responden adalah 21 orang yang merupakan pasien yang datang ke Posko Pelayanan di Desa Petang. Pemeriksaan dilakukan dengan mengisi Formulir Pemeriksaan Kesehatan Gigi dan Mulut WHO. Datamenunjukan bahwa tidak ada responden yang menggunakan gigi tiruan. Disimpulkan bahwa pemakaian gigi tiruan masih sangat rendah menunjukkan kurangnyapengetahuan masyarakat dalam upaya pemeliharaan kesehatan gigi dan rendahnya kesadaran masyarakat dalam mempertahankan fungsi gigi dan estetik.
Effectiveness of neem leaf extract (Azadirachta Indica A. Juss) against C.albicans on acrylic resin plates: Efektivitas ekstrak daun mimba (Azadirachta Indica A. Juss) terhadap C.albicans pada plat resin akrilik Helena Jelita; Sintha Nugrahini
Makassar Dental Journal Vol. 10 No. 1 (2021): Volume 10 Issue 1 April 2021
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v10i1.381

Abstract

Denture stomatitis, the main cause of which is Candida species, especially C.albicans, is an inflammation of the oral mucosa of removable denture users which can be associated with reactions to oral biofilms, denture materials, or trauma due to dentur-es. The use of chemicals as denture cleaners can increase the roughness of the base surface, so that herbal ingredients can be used as alternative denture cleaners. Neem leaves (Azadirachta Indica A. Juss) contain active ingredients that can kill bacte-ria and fungi, in the form of azadirachtin, salannin, meliantriol, and nimbin as well as tannin compounds, saponins, flavonoids and terpenoids which have antifungal mechanisms. This research was aimed to determine the effectiveness of neem leaf extract against C.albicans on acrylic resin denture plates. The sample of this posttest only control group design study consisted of 24 acrylic resin plates contaminated with C.albicans suspension. After that, the samples were immersed in 4 groups of disinfectant solutions, namely 5% EDM, 10% EDM, aquadest and Polident® for 30 minutes. The number of C.albicans colonies was tested by Kruskal Wallis and U Mann Whitney. The results showed that the mean C.albicans colony in the EDM 5%, 10% EDM, aquadest and Polident® groups were 21.50 CFU/mL, 15.50 CFU/mL, 27.50 CFU/mL, 6.50 CFU/mL respectively. Neem leaf extract significantly decreased the number of C.albicans colonies (p <0.005). It was concluded that the higher the EDM con-centration, the greater its ability to reduce the number of C.albicans colonies.
Effect of river water and groundwater pH quality to the teeth calcium level solubility in Kereng Bangkirai area, Central Kalimantan Province: Pengaruh kualitas pH air sungai dan air tanah terhadap kelarutan kadar kalsium gigi di daerah Kereng Bangkirai, Provinsi Kalimantan Tengah Helena Jelita; Sintha Nugrahini
Makassar Dental Journal Vol. 10 No. 3 (2021): Volume 10 Issue 3 Desember 2021
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v10i3.459

Abstract

Background: Communities along the river in the Kereng Bangkirai area use river and groundwater (wells) for daily needs such as cooking and cleaning themselves and for other needs. It is important to know the quality of the water used by the people in the area, especially related to health conditions regarding the to the levels of dental calcium dissolved. Purpose: This study was aimed to prove the effect of pH quality dental calcium levels dissolved in river and groundwater from Kereng Bangkirai area. Method: This laboratory experiment with a control time series design was using groundwater, river water, aquadest and 36 per-manent human premolars with special criteria. The teeth were soaked for 5, 10, 15, 30, 45, 60 minutes and then measured the level of calcium solubility using a UV-vis spectrophotometer, then the average of dissolved calcium levels in the water was mea-sured. Result: Acidity of aquadest, groundwater and river water were 7.0, 4.08, and 3.16, consecutively; showed that the river water has a high level of pH. The average value of calcium solubility of aquadest was 3,534, in groundwater was 12,682 and the highest 17,882 in river water. Conclusion: Acidity level of river water and groundwater from Kereng Bangkirai area may affect calcium solubility of teeth.
Co-Authors Dewi Farida Nurlitasari Dewi, Intan Kemala Helena Jelita Helena Jelita I Made Agus Astika Kadek Dwi Dessy Sapitri Putu Hanny Ardianingsih Wirayuni, Kadek Ayu