Weed control is one of the determining factors for achieving high oil palm yields, at the same time fertilization is necessary to provide nutrients for plants. This study aims to: (1) determine the interaction between the herbicide IPA Glyphosate with fertilizer Urea+SP-36+KCl on weed control and growth of immature oil palm. (2) to obtain an effective dose of herbicide to control weeds, and to obtain the best dose of Urea+SP-36+KCl fertilizer for the growth of oil palm. The study was conducted using a factorial Randomized Block Design (RBD) consisting of 2 factors and 8 treatment combinations. The first factor is herbicide doses of IPA Glyphosate (1,920 g/ ha, 2,400 g/ha, mechanical weeding, and control) and the second-factor is fertilizer doses of Urea+SP-36+KCl (600 g Urea +750 g SP-36 +700 g KCl/plant, and 700 g Urea + 850 g SP- 36 + 800 g KCl/plant). The data were analyzed for variance and if significantly different then continued with Duncan’s New Multiple Range Test (DMNRT) at the 5% level. The results showed that there was no interaction between the dose of the herbicide IPA Glyphosate with fertilizer Urea+SP-36+KCl on weed control and growth of immature oil palm. The herbicide dose of I PA Glyphosate which was effective in suppressing the dry weight of weeds was 1,920 g/ha because it was effective in suppressing the dry weight of weeds up to 12 weeks after application (WAA) and obtained the smallest average of weed dry weight. Urea+SP-36+KCl fertilizer application did not affect the vegetative growth parameters of immature oil palm.