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REGENERASI SIRIP KAUDAL IKAN GATUL (Poecilia sp.) YANG MENGALAMI MALFORMASI Iza, Nikmatul; Listyorini, Dwi; Gofur, Abdul
Edubiotik : Jurnal Pendidikan, Biologi dan Terapan Vol 1 No 01 (2016): Edubiotik
Publisher : Program Studi Pendidikan Biologi, IKIP Budi Utomo Malang

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Abstract

Gatul fish in included in the family Poecilidae which is a small fresh water, male is smaller and more colorfull than female. This fish is easy to be taken care in laboratory and has a short reproduction cycle, thus allowing these fish to be one animal model development in the field of biology. Yet, in Indonesia the biological study upon Gatul fish is very limited. The aim of this study is to understand the process of caudal fin regeneration of Gatul fish are malformation (abnormal growth). Caudal fin of Gatul fish were vertically cut in a half of its length. Observation was done using 400x magnification. Picture with taken by camera with digital zooming. The subject of this study with a body length of 2-3 cm. The result shows that regeneration of Gatul caudal fin is started with wound healing in day-1 (D1= 24 hours after amputation) and blastema formation, then stump regeneration begin to grow in D2. Regenerative outgrowth begin in D3 characterized by the formation Blood island and fin rays. Differentiation begin in D6 and extended up to D18. From this research we can conclude that the process is going step by step through wound healing, stump growth, and tissue differentiation, and respectively
PENGARUH KUALITAS PELAYANAN DAN HARGA TERHADAP KEPUASAN PELANGGAN Gofur, Abdul
Jurnal Riset Manajemen dan Bisnis (JRMB) Fakultas Ekonomi UNIAT Vol 4 No 1 (2019)
Publisher : Economic Faculty, Attahiriyah Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36226/jrmb.v4i1.240

Abstract

The purpose of this study is to determine the effect of service quality and price on customer satisfaction. This study uses an associative method with a quantitative approach. The research sample is the regular customers of the company PT. Indosteger Jaya used accidental sampling technique and obtained 80 respondents. Data analysis using multiple linear regression. The results of this study indicate that service quality has a positive and significant effect on customer satisfaction and price has a positive and significant effect on customer satisfaction (Y). Other results, that together service quality and price have a positive and significant effect on customer satisfaction. Keywords: Service Quality, Price, Consumer Satisfaction
Single Clove Garlic (Allium sativum) Essential Oil as an Inhibitor of Staphylococcus aureus Bacteria Gofur, Abdul; Wulandari, Ida; Athoillah, M. Fitri; Witjoro, Agung; Lestari, Sri Rahayu
Biosaintifika: Journal of Biology & Biology Education Vol 11, No 1 (2019): April 2019
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (312.475 KB) | DOI: 10.15294/biosaintifika.v11i1.13944

Abstract

Staphylococcus aureus is gram-positive bacteria that often infect the skin. S. aureus has been experiencing resistance to several antibiotics. One of the solutions to overcome the resistance is by using garlic that is believed by the society can overcome bacterial infection. The study aimed to find out the influence of the variation in concentration of local single clove garlic essential oil used on the inhibition and damage of morphological structure of S. aureus bacteria. The inhibition test was conducted using disc diffusion method. The experiment groups consisted of  1% DMSO as negative control, vancomycin 30µg/ml as positive control and single clove garlic essential oil (25 mg/ml, 50 mg/ml, 75 mg/ml and100 mg/ml) as treatment groups. The diameter of inhibition zone was measured using calipers. The morphological damage of the bacterial cells can be seen using Scanning Electron Microscopy (SEM) with magnification of 25000x. The result of Kruskal-Wallis test analysis indicated that the extract of local garlic essential oil has inhibitory activities against S. aureus bacteria (P<0.05). The damage to the morphological structure of bacterial cells with the administration of 30 µg/ml vancomycin was equal to 100 mg/ml single clove garlic essential oil extract. Single clove garlic essential oil can be used as an alternative treatment for skin infection diseases by inhibiting S. aureus growth.
Single bulb garlic oil improves interleukin-6 via decreased reactive oxygen species (ROS) in high-fat diet male mice Ilmawati, Riza Rahayu; Gofur, Abdul; Lestari, Sri Rahayu
Universa Medicina Vol 38, No 2 (2019)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (45.056 KB) | DOI: 10.18051/UnivMed.2019.v38.100-107

Abstract

BackgroundHigh-fat diet (HFD) is highly responsible for the development of excessive reactive oxygen species (ROS). ROS and low-density lipoprotein (LDL) then trigger macrophage activation to secrete interleukin-6 (IL-6). Single bulb garlic or in Indonesian called bawang lanang is traditional medicine that possesses strong antioxidant properties. This study aimed to evaluate the effect of single bulb garlic oil (SBGO) on ROS, IL-6, and lymphocyte density in HFD-fed male mice.MethodsThis was an experimental study on 24 male mice randomly subdivided into 6 groups: one group was fed a normal diet, whereas the remaining five groups were fed HFD for 45 days and were then treated with single bulb garlic oil 0 mg/kg, simvastatin 26 mg/kg BW, single bulb garlic oil 12.5 mg/kg BW, 25 mg/kg BW, and 50 mg/kg BW respectively for the next 35 days. At the end of treatment, the mice were dissected for collection of (i) serum in order to measure ROS and IL-6 levels using ELISA, (ii) aortas to measure IL-6 expression using immunohistochemistry-fluorescence (IHC-F) and to obtain lymphocytes from bone marrow and spleen which were then counted using a light microscope.ResultsOur results indicated that SBGO decreased the ROS level, IL-6 level, IL-6 expression, and lymphocyte density in HFD mice. SBGO 12.5 mg/kg BW is the optimum dose in our study to reduce inflammation in HFD male mice.ConclusionSBGO is useful to reduce inflammation and improve antioxidant imbalance, thus might be a potential antiatherogenic agent.
The Protective Role of Single Bulb Garlic Towards Vascular Cell Adhesion Molecules-1 (VCAM-1) on Mice With High-Fat Diet Chasanah, Isfatun; Gofur, Abdul; Lestari, Sri Rahayu
Jurnal Akademika Kimia Vol 8, No 2 (2019)
Publisher : Universitas Tadulako

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Abstract

Atherosclerosis is initiated by inflammatory response characterized by the accumulation of lipids in the arteries, causing blockage of blood vessels. The excessive of Low-Density Lipoprotein (LDL) in the blood is a major factor in endothelial dysfunction and results in an inflammatory process. The inflammatory process in atherosclerosis is due to the expression of adhesion molecules Vascular Cell Adhesion Molecules-1 (VCAM-1). This research aims to evaluate the effect of single bulb garlic oil extract (SGBOE) against VCAM-1 expression high-fat diet mice. Male mice strain Balb/C were acclimatized for one week. Mice were divided into 6 groups (n=5): normal, high-fat diet (HFD), HFD + simvastatin, and HFD + SBGOE 12.5, 25, and 50 mg/kg BW respectively. HFD was given for 45 days. Single garlic extract was given for four weeks orally. The aortic VCAM-1 expression was assayed using the Immunohistochemical-Flouresence (IHK-F) method. The result of One-Way ANOVA showed that the treatment influenced significantly (p<0.05). The foam cells increase in the high-fat diet group compared than normal mice. Dose 12,5 mg/kg BW reduces VCAM-1 expression near the normal group. Allicin and S-allyl cysteine (SAC) compounds in single bulb garlic are antioxidant compounds that act to prevent oxidative stress and prevention mechanisms against lipoprotein modification.
PENGARUH CELAH FIN, SUDUT KEMIRINGAN FIN DAN CELAH SUDU TERHADAP KINERJA TURBIN ANGIN SAVONIUS TYPE V Kastiawan, I Made; Gofur, Abdul; Catur Pamungkas, Angga; Budianto, Aries
MEKANIKA: Jurnal Teknik Mesin Vol 3 No 01 (2017): July
Publisher : Program Studi Teknik Mesin, Universitas 17 Agustus 1945 Surabaya

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Abstract

This article is the result of research on wind turbine savonius type V. In thisresearch designed 4 blade type V which has angle 110 ÌŠ. This windmill analyzes the effect offin gaps, fin angle and blade slits. This windmill is designed by analyzing the lowest wind byutilizing the wind speed of passing vehicles on the road. The results of the study showed that5 mm fin breaks, a1 blade slits, b1 (5mm, 2.5mm) and fin angle of 30 ÌŠ can improve goodperformance. These results are evidenced by a maximum rotation speed of 96.7 Rpm and amaximum force of 1.4 N.
PERILAKU MISTIK KELOMPOK PECANDU TOTO GELAP (TOGEL) DI DESA KASIYAN PUGER JEMBER Gofur, Abdul; Sulomo, Sulomo
Jurnal ENTITAS SOSIOLOGI Vol 1 No 2 (2012)
Publisher : Laboratorium Sosiologi FISIP Universitas Jember

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Abstract

This research was intended to determine and describe the behaviors of Toto Gelap (Togel)-addicted people in Kasiyan Village, District of Puger, Jember regency. The research used symbolic interactionism theory of Blumer. Togel activities done by the community are not always caused by economic reasons that make someone to do Togel gambling. Some reasons are by hobbies, lifestyle, and consideration as a determinant of social status. Besides, in determining Togel coupon, Togel-addicted people use unique ways by the mystical path. On the other hand, the things related to the mystique have been a habit, tradition, and belief handed down from generation to generation. The research used descriptivequalitative methods, and informants were determined by purposive sampling. Data collection methods used were structured observation, in-depth interviews, and documentation. Togel in Kasiyan Village, District of Puger, Jember Regency has been growing since the 2000s. Togel-addict group has some mystical behaviors, which include: dream interpretation, grandong (an activity done on a grave for getting signs/information from spirits), natural code, meditation, spirituality, and fortune-telling. Besides, Togel gambling has special functions and meanings for togel-addicted people as a source of income, a shortcut to debts settlement, and marketing strategies. Meanwhile, the meanings of Togel gambling for togel-addicted people are as a medium of channeling the desire to gambling, gambler togetherness tier, and a means of affirming the identity of gamblers. Keywords: addicts, togel, mystical behaviors.
The Role of Black Soybean and Purple Sweet Potato Active Compound on Advanced Glycation End-Product in Streptozotocin-Induced Type 2 Diabetes Mellitus Rat Gofur, Abdul; Arifah, Siti Nur; Annisa, Yuslinda; Witjoro, Agung; Atho'illah, Mochammad Fitri; Lestari, Sri Rahayu
Journal of Tropical Life Science Vol 9, No 2 (2019)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.09.02.02

Abstract

Diabetic nephropathy is one of the diabetes complications attacking kidney leading to kidney damage. Hyperglycemia accompanying DM causes the increase of Ad-vanced Glycation End-Product (AGE) and Receptor Advanced Glycation End-Product (RAGE) activity, then develop kidney damage and other diabetes compli-cations. The study aimed to investigate the effect of black soybean, purple sweet potato, or their combination on the expression of AGE, RAGE, and kidney necro-sis T2DM model rats. The rats were given with high-calorie diet for five weeks and then injected with a low dose of streptozotocin (30 m/kg Body Weight) in intraperitoneal. DM rats were divided into: normal, K- (T2DM), K+ (T2DM + glibenclamide 0.6 mg/kg body weight), P1 (T2DM + black soybean), P2 (T2DM + purple sweet potato), and P3-5 Combination 1-3 (T2DM + combination of black soybean and purple sweet potato in ratio of 1 : 3, 2 : 2, and 3 : 1). DM rats were then given the treatments for thirty days. The effect of black soybean, purple sweet potato, or the combination of both was evaluated through the expression of AGE, RAGE, and necrosis of renal tubules. The changes in renal tubules histological characteristics were evaluated using hematoxylin-eosin (HE) staining. Immuno-histochemistry analysis of renal tubules was to evaluate AGE-RAGE expression after the treatments. The research results indicated that there was a significant dif-ference from the combination of black soybean and purple sweet potato in reduc-ing AGE, RAGE, and renal tubules necrosis. The BSB and PSP combination ratio of 1:1 was able to improve renal tubules, decrease the expression of AGE and RAGE towards near normal. The combination of black soybean and purple sweet potato could be used as one of the alternatives to improve kidney damage in dia-betic nephropathy.
THE SCIENTIFIC LITERACY PERFORMANCE OF GIFTED YOUNG SCIENTIST CANDIDATES IN THE DIGITAL AGE Fausan, Muhammad Mifta; Susilo, Herawati; Gofur, Abdul; Sueb, Sueb; Yusop, Farrah Dina
Jurnal Cakrawala Pendidikan Vol 40, No 2 (2021): Cakrawala Pendidikan (June 2021)
Publisher : LPMPP Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/cp.v40i2.39434

Abstract

Scientific Literacy (SL) is an important competency to deal with and keep up with the increasingly sophisticated technological developments. However, information about the SL of prospective gifted young scientists over 15 years old has not been widely revealed holistically. Therefore, this survey research aimed to investigate the SL performance of prospective gifted young scientists holistically and compare the SL performance based on the grade level. A total of 278 students from a public senior high school in Jombang Regency, East Java Province, Indonesia, participated in this research. They were asked to take the SL test with 18 essential question items. As a result, the participants still showed low SL performance (total success rate = 40). The one-way ANOVA test results indicated no significant difference in the participants' SL performance based on the grade level. Therefore, three recommendations were provided: teachers should use various learning models, SL should be an explicit focus in science and non-science classrooms, and schools need to be equipped with supporting facilities to accommodate student readiness to practice SL.
RANCANG BANGUN PROTOTIPE ALAT PENYARING AIR LIMBAH BATIK MENGGUNAKAN METODE MULTIMEDIA FILTER BERBASIS MIKROKONTROLER Gofur, Abdul; SUPRIYADI, SLAMET; MUKHTAR, AGUS
MEKANIK: Jurnal Ilmiah Teknik Mesin Vol 7 No 2 (2021): Juni - November 2021
Publisher : Jurusan Teknik Mesin, Fakultas Teknologi Industri, Institut Teknologi Medan (ITM)

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Abstract

Perkembangan industri semakin meningkat dari masa kemasa, salah satunya adalah industri batik yang merupakan karya seni budaya bangsa Indonesia yang telah turun-temurun. Dalam industry batik, pewarnaan adalah proses yang sangat penting dant tidak mungkin ditinggalkan. Proses ini menggunakan pewarna tekstil yang menghasilkan limbah dan dapat mencemari lingkungan. Keberadaan industri batik di Indonesia menempati kategori industry skala besar, menengah, kecil dan bahkan skala rumahtangga (home industry). Hal ini menyebabkan pencemaran yang ditimbulkan oleh industri batik tidak hanya terjadi pada kawasan industri, tetapi terjadi juga di pemukimaman padat penduduk. Salah satup pengolahan air limbah batik yaitu dengan menggunakan alat penyaring air dengan metode multimedia filter.Dari hasil pengujian menunujukan bahwa variasi susunan pertama atau VS 1 (Ijuk – pasiraktif – karbonaktif – zeolit.) yang paling bagus dalam melakukan filtrasi atau penyaringan dengan rincian nilai kekeruhan 347,37 NTU dengan nilai standar yaitu 400 NTU hamper mendekati namun belum mencapai batas yang ditentukan, sedangkan nilai suhu yaitu 28,50 ºC dengan standar suhu yakni kisaran 20 -30 ºC, kemudian nilai pH yang dihasilkan semuanya sama yaitu 8,4 dan nilai kadar DO (Dissolved Oksigen) yaitu 4.25 mg/L dengan standar parameter yakni 5 mg/L hasil tersebut hamper mendekati standar budidaya ikan air tawar namun belum pas padastandar yang ada. Kata kunci : Airl imbah batik, efektivitas saringan, multimedia filter, mikrokontroler