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All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science) Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Majalah Kedokteran Andalas

Enikarmila Asni

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Author-ID : 461880

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Public Health

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Kristal Hemoglobin Pada Bercak Darah yang Dipaparkan Sodium Hipoklorit (NaOCl) Menggunakan Tes Teichmann Dan Tes Takayama Romdonah Romdonah; Radha Zatti Rahmi; Tegar Mohammad Indrayana; Fridayenti Fridayenti; Enikarmila Asni
Jurnal Ilmu Kedokteran Vol 11, No 1 (2017): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Bloodstains is an important body fluids as evidence, because the blood has hemoglobin structure consisting of hemeand polypeptides. Perpetrators will attempt to clean the bloodstain that found at the crime scene by using cleaningagents and chemicals. Sodium hypochlorite is a chemical that found in cleaning fluids and bleach. This study aims toknow the effects of sodium hypochlorite to bloodstain and confirmatory test. Bloodstain on the objeck glasses andthe fabrics exposed by sodium hypochlorite concentration 5,25% and 0,15%, and examined with Teichmann’s testand Takayama’s test, and seen under microscope. In this study, show no crystal hemoglobin of the bloodstain on theobjeck glasses and fabrics exposed by sodium hypochlorite concentration 5.25% and concentration 0,15%. Thismight caused by sodium hypochlorite destructed structure of heme, so there were no reaction between heme, sodiumchloride and acetat glacial acids on Teichmann’s test and no reaction between heme and Takayama’s reagen onTakayama’s test. The conclusions of this study, crystal hemoglobin were not found on bloodstain exposed by sodiumhypochloryte using Teichmann’s test and Takayama’s test.

Pengaruh Pemberian Asam Alfa Lipoat terhadap Kadar Kolesterol Total pada Tikus Diabetes Melitus Tipe 2 Uli Kartika Lestari Sinaga; Ismawati Ismawati; Enikarmila Asni
Jurnal Ilmu Kedokteran Vol 11, No 2 (2017): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Hypercholesterolemia is complication in type 2 diabetes. Alpha lipoic acid (ALA) reduced total cholesterol by modulatingcholesterol synthesis pathway and reduced cholesterol biosynthesis genes expression. The goal of this research wasto investigate the prohibition of hypercholesterolemia in type 2 diabetes rat by ALA. Fifteen adult male wistar rats (2-3 months, 200-250 g body weight) were segregated into three groups (standard, type 2 diabetes and type 2 diabetes +ALA). Type 2 diabetes induced by streptozotocin 65 mg/kg and nicotinamide 110 mg/kg. ALA was given for 3 weeksafter type 2 diabetes induced.After 31 days total cholesterol of groups labelled is measured. The result showed therewas significant difference between ALA and type 2 diabetes groups (p= 0.012), and there was no significant differencebetween ALA and standard groups (p= 0.591). As the conclusion, this study proves that ALA has effects on totalcholesterol in type 2 diabetes rats.

Pengaruh Hemodialisis Terhadap Kadar Glutation Tereduksi (GSH) Plasma Pasien Hemodialisis RSUD Arifin Ahmad Hannan Khairu Anami; W. Ristua Butar-Butar; Enikarmila Asni
Jurnal Ilmu Kedokteran Vol 5, No 1 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Chronic kidney disease patients who received hemodialysis therapy have higher risks to get atherosclerosis, inflammation,and cancer than general population at the same age. Imbalance of free radicals level and antioxidants defense whichdefined as oxidative stres may cause these complications. This study investigated the influence of hemodialysis onreduced glutathione (GSH) level, one of antioxidant, in blood plasma of hemodialysis patient at RSUD Arifin Ahmad.This was a cross sectional study that compare plasma GSH level before and after hemodialysis process. Population ofthis study was 72 patient in RSUD Arifin Ahmad but only 17 patient fulfilled all the inclusion and exclusion criteria.Plasma GSH level was measured by using Ellman method. The result showed that there were no significant differenceof plasma GSH level in patient before and after hemodialysis process (p=0,426).

Faktor-faktor yang Mempengaruhi Partisipasi Mahasiswa dalam Proses Tutorial pada Metode Belajar Problem-Based Learning (PBL) di Fakultas Kedokteran Universitas Riau M Yulis Hamidy; Enikarmila Asni
Jurnal Ilmu Kedokteran Vol 4, No 1 (2010): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Problem-based Learning (PBL) is an effective approach to promote student-centered learning. PBL tutorials were thekey step in PBL process. Students’ participation in PBL tutorials can be influenced by many factors. The aim of thisstudy was to identify the factors that influence students’ participation in PBL tutorials among students in Faculty ofMedicine University of Riau. The research was a cross sectional study using self report questionnaires obtained fromPBL students, conducted in April - October 2009. The students’ participation was assessed using Visschers-Pleijersquestionnaires. The result revealed the characteristics of parcipants which are female (79.5%), 19 years old (40.2%),had GPA 2.50 – 3.00 (56.7%), had past experience in organization (89.0%). Among 44.1% of the participants showedactive participation in tutorial processs. Male students more likely active than female students (P = 0.045). Anotherfactors including age, GPA, past experience in organization, role of tutors, and quality of scenario were not influencedthe participation of subject. Students’ participation in PBL tutorials among students in Faculty of Medicine Universityof Riau was influenced by sex.

HUBUNGAN LAMA PEMBERIAN DIET ATEROGENIK TERHADAP KADAR TRIGLISERIDA Rattus novergicus JANTAN STRAIN WISTAR Renti Sulvia Niza; Enikarmila Asni; Wiwit Ade Fidiawati
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 2 (2015): Wisuda Oktober 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTCardiovascular diseases is the disruption and damage of the heart muscleand the number one cause of death worldwide. Based on epidemiologic data andclinical trial results support an association between elevated triglyceride andCardiovascular risk. The goal of this research is to know the correlation of givenduration atherogenic diet againts triglyceride level in male wistar rats. Thisresearch was experimental with the post test-only control group design, by usingmale rats (Rattus novergicus) of 2-3 month with the average weight range of 160-240 g. The rats were divided into 4 group, control group given with standard diet,the 5 weeks atherogenic diet group, the 8 weeks atherogenic group and 12 weeksatherogenic group, in which group consist of 6 rats. The atherogenic diet (2%cholesterol of yolk, 5% goat’s fat, and 0,2% cholic acid) were given as much as20 g/each/day. The result showed a significant difference (p=0,000). As for thepost hoc test (p=0,000), there is a statistically significant difference within theexperimental groups. As for the spearman test (0,969), it shows a significantpositive correlation between the given duration of the atherogenic diet and thetriglyceride level. It can be concluded the longer time that the rats gotatherogenic diet showed the level of triglycerides rats (Rattus novergicus)increased.Keywords: Atherogenic diet, triglyceride level, rats (Rattus novergicus).

KRISTAL HEMOGLOBIN PADA BERCAK DARAH YANG TERPAPAR OLEH BEBERAPA DETERJEN BUBUK MENGGUNAKAN TES TEICHMANN DAN TES TAKAYAMA Serli Marcelisa; Enikarmila Asni; M. Tegar Indrayana
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 2 (2015): Wisuda Oktober 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTBloodstain is one of the body fluid which might drop in some criminal case. Investigating bloodstain is very useful to solve a criminal case and can be an evidance. There are some ways to eliminate the evidance for example wash the bloodstain from victim’s cloth. The purpose of this research are to know the description of hemoglobin crystal exposed by some detergent powder using Teichmann test and Takayama test. Teichmann test and Takayama test are forensic laboratory examination that can help to prove the formation of hemoglobin crystals. The reserch was an experimental study conducted in a University Medical School Biochemistry Laboratory Riau. Exposure method in this research is to be streamed. The results of this research was still finding hemoglobin crystals in 14 (100%) slide that have been drained of bloodstain using 7 brand deterjen powder. The conclusion of this reserch is bloodstain that has beeb exposed to detergent powder still gaves an overview of hemoglobin crystals.Keywords : bloodstain, detergent powder,hemoglobin crystals, Teichmann test, Takayama test

UJI FORMALIN PADA IKAN ASIN GURAMI DI PASAR TRADISIONAL PEKANBARU Nadya Yulisa Yulisa; Enikarmila Asni; Miftah Azrin
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 1, No 2 (2014): Wisuda Oktober Tahun 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Formalin is aqueous solution of chemical compund formaldehyde (30-50%) and methyl alcohol (10-20%). Missapropriation of formalin as perservatives has became society common issue, which was the use of formalin on foods, such as salted carps. This study aimed to determine the formaldehyde substance in salted carps that sold in traditional markets. This is a descriptive laboratory study where 6 traditional markets administered by the Office of Pekanbaru City Market have obtained as samples. Tests were conducted in the Laboratory of Biochemistry Faculty of Medicine, University of Riau. Qualitative study was to see whether or not salted carps contained any formaldehyde substances and semi-quantitative study was to determine the formaldehyde concentrate in salted carps. Examination of 20 salted carps as samples showed a qualitative result that all samples positively contained formaldehyde, which was indicated by the purple color in the formalin test. Result of semi- quantitative test showed a diversity of formaldehyde concentration in the range 1.89 % - 7.66%, which was leading to a conclusion samples wether population were positively contained formaldehyde.Key word: formaldehyde, salted carp, traditional market

HISTOPATOLOGI ARTERI KORONARIA Rattus novergicus STRAIN WISTAR JANTAN SETELAH PEMBERIAN DIET ATEROGENIK SELAMA 5 MINGGU Annisa Ul Hasanah; Enikarmila Asni; Zulkifli Malik
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTAtherosclerosis is a complex chronic disease characterized by the accumulation of lipid, trombosits, neutrophils, monocytes, and macrophages within arterial walls. Atherosclerosis could be induced in animal model ( Rattus novergicus ) by feeding atherogenic diet. The goal of this research was to analyze histopathological of coronary artery on male Rattus novergicus strain wistar after fed atherogenic diet for 5 weeks. This research was an experimental laboratory research with post test only with control design. Twelve male rats were segregated into two groups ( n=6 ) labelled as control fed standart and atherogenic group fed atherogenic diet containing cholic acid 0,2%, fat 5%, egg yolk 2% and induction with vitamin D3. After 5 weeks coronary artery was taken and histological slides were made and colored with Hematoxylin Eosin. The measured parameter were atherosclerosis lession score. The result showed 66% sampels that given standart diet and 100% sampels that given atherogenic diet showed atherosclerosis lession.The statistical test result showed there is no significant difference between control group and atherogenic group. ( p=0,328 ). The conclusion, atherosclerosis occurred in 4 sampels ( 66% ) of control group and 6 sampels ( 100% ) of atherogenic group. There was no significant difference in coronary artery histopathology Rattus novergicus between the control group with atherogenic group.Keywords : Atherosclerosis, atherogenic diet, coronary artery.

Kristal hemoglobin pada darah dan bercak darah yang terpapar beberapa shampo cuci sepeda motor menggunakan tes Teichmann dan tes Takayama M. Fajrul Ihsan; Enikarmila Asni; Mohammad Tegar Indrayana
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 2 (2015): Wisuda Oktober 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTBloodstain is one of important evidence in a forensic laboratoryexamination, especially in cases o violence or crime. Attempted in removingevidence of bloodstain with cleaning agents such as motorcycle wash shampoo isa challenge in the investigation. The purpose of this study is to observe crystalhemoglobin in blood and bloodstains exposed with motorcycle wash shampoousing Teichmann and Takayama test. This study is experimental research. Theblood slides and bloodstains slides were washed using 2 kind of motorcycle washshampoo as many as one to three times. In the study, 28 (100%) slides havepositive result whether with Teichmann or Takayama test. It can be concludedthat hemoglobin crystal are still can be found in blood and bloodstain expand willsome motorcycle wash shampoo using Teichmann and Takayama test.Keywords: bloodstain, hemoglobin crystal, motorcycle wash shampoo,Teichmann, Takayama

PENGARUH LAMA PEMBERIAN DIET ATEROGENIK TERHADAP INDEKS ATEROGENIK SERUM Rattus novergicus STRAIN WISTAR JANTAN Ariza Julia Paulina; Enikarmila Asni; Mardhiah Gaffar
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 2 (2015): Wisuda Oktober 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Atherosclerosis is defined as a chronic inflammation which is marked by the accumulation of cholesterol and ester cholesterol in the sub endotelial vascular tissue. The ratio of LDL/HDL (atherogenic index) is the main parameter in atherosclerosis and CHD incidence. The purpose of this research is to know the effect of long giving atherogenic diet against serum atherogenic index in male Wistar rat. This study was an experimental research with the post test-only control group design, by using male rats (Rattus novergicus) of 2-3 month with the average weight range of 160-240 gr. The rats are then divided into 4 group which are: control group given with standard diet, the 5 weeks atherogenic diet group, the 8 weeks atherogenic group, and the 12 weeks atherogenic group, in which group consist of 6 rats. The atherogenic diet (2% cholesterol, 5% goat’s fat, and 0,2% cholic acid) is given ad libitum as much as 20 gr/ea/day. The result are then analyzed with the one way ANOVA method, showing that there’s a adequate difference (p=0,000). As for the Post Hoc Test (p=0,000), the result show is that the atherogenic diet does increase the atherogenic index of the rats blood serum. And as for the Spearman test (0,969), it show is a significant positive correlation between the atherogenic index and the given duration of the atherogenic diet. In this research we can conclude that the longer given atherogenic duration, the higher the atherogenic index will become on male Wistar rats (Rattus novergicus).Keywords: Atherosclerosis, atherogenic diet, atherogenic index, LDL/HDL ratio, rats (Rattus novergicus)

Co-Authors Annisa Ul Hasanah Anwar Syaputra Ariza Julia Paulina Bulqis Vellaya Arlem Daviq Chairilsyah Erriza Yuni Elpia Fika Maulidah Fridayenti Fridayenti Hannan Khairu Anami Hilda Fauziah Lainatus Shifa Ismawati Ismawati Ivon Gemiyani Nafriti Gemiyani Lilly Haslinda M Yulis Hamidy M. Fajrul Ihsan M. Tegar Indrayana M. Yulis Hamidy Mardhiah Gaffar Miftah Azrin Mohammad Tegar Indrayana Muhammad Nasir Nadya Yulisa Yulisa Neneng Mutiara Sari Radha Zatti Rahmi Renti Sulvia Niza Rica Dhamayanti Romdonah Romdonah Serli Marcelisa Sherty Amelia Sutrisno Tambunan Tegar Mohammad Indrayana Uli Kartika Lestari Sinaga W. Ristua Butar-Butar Wan Risa Mailina Wiwit Ade Fidiawati Zulharman " Zulkifli Malik

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