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The Genistein Daidzein in Kudzu Root (Pueraria lobata) Extract Decreased Malondialdehyde Plasma Levels in Hypoestrogenic Rats Nany Nita Noviana; Nina Rini Suprobo; I Wayan Arsana Wiyasa
Asian Journal of Health Research Vol. 1 No. 1 (2022): Volume 1 No 1 (April) 2022
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (830.269 KB) | DOI: 10.55561/ajhr.v1i1.6

Abstract

Introduction: Menopause can reduce women's quality of life and cause health issues. The decline in estrogen during menopause is thought to trigger oxidative stress. When the creation of antioxidants does not match the synthesis of reactive oxygen species (ROS) as an antidote, oxidative stress ensues, characterized by malondialdehyde. The aim of the research is to evaluate the effect of the dose of isoflavone genistein daidzein powder in Kudzu root (Pueraria lobata) extract on the decrease in plasma malondialdehyde (MDA) plasma levels in hypoestrogenic rats. Methods: 30 rats Wistar rats were separated into five groups, namely: the control group, the ovariectomy (OVX) group, waited two weeks to produce hypoestrogenic rats. Of the four groups, the positive group was not given a Pueraria lobata powder containing the isoflavones genistein and daidzein (IGD), and the other group was given 15 mg, 30 mg, 60 mg per kg body weight per day, respectively. Twenty-one days later, the mice were killed, and plasma was taken to be checked for MDA levels using spectrophotometry. Results: Genistein Daidzein in kudzu root extract was effective in reducing the oxidative stress. All IGD doses significantly reduced plasma MDA levels. At a dose of 60mg/kg BW, the plasma MDA levels were comparable to those in the control group, it could prevent a significant increase in plasma MDA levels in hypoestrogenic rats. Conclusion: Isoflavone Genistein and Daidzein of kudzu root (Pueraria lobata) extract reduced MDA plasma levels in hypoestrogenic rats.
Early Breastfeeding Initiation Effect in Stunting: A Systematic Review Steven Christian Susianto; Nina Rini Suprobo; Maharani Maharani
Asian Journal of Health Research Vol. 1 No. 1 (2022): Volume 1 No 1 (April) 2022
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (816.006 KB) | DOI: 10.55561/ajhr.v1i1.11

Abstract

Introduction: Stunting has been a global burden worldwide, resulting in severe outcomes, including inadequate brain development until mortality. Early breastfeeding initiation as a global strategy affects the success of continuous breastfeeding that influences the children’s growth and development. This study aimed to provide a literature review on how early breastfeeding initiation might help children avoid stunting. Methods: We searched articles published from 2017 to 2022 in PubMed, Science Direct, Cochrane, and the Indonesia Database with keywords “Early breastfeeding initiation” OR “Early breastfeeding” OR” Early Initiation Breastfeeding” AND “stunting.” All data were gathered and analyzed. Results: A total of 12 articles from 6690 articles met the inclusion, exclusion, and eligibility criteria. The mean of early breastfeeding initiation was 61,82%, with the lowest study in Chimborazo and Tungurahua, Ecuador, and stunting was 33,07% as the highest prevalence was in Chimborazo and Tungurahua, Ecuador, while the lowest in Saharawi refugee camps, Algeria. The mean prevalence of children who did not get early breastfeeding initiation and stunting occurred at 40,85%, and eight studies reported that early breastfeeding initiation was associated with stunting. Conclusion: Early breastfeeding initiation can lower stunting risk in children. Early breastfeeding initiation ensures children obtain enough colostrum that enhances the children’s immunity and probability of exclusive breastfeeding, ensuring children obtain adequate nutritional intake and prevent stunting.
Balanced Nutrition Education in School-Age Children: A Community Service Rizqie Putri Novembriani; Nina Rini Suprobo; Elisa Danik Kurniawati; Winny Kirana Hasanah
Indonesian Journal of Health Care Management Vol 3, No 1 (2022): Indonesian Journal of Health Care Management (IJOHCM)
Publisher : STIKes Kepanjen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36053/ijohcm.v3i1.38

Abstract

Investing in child nutrition is critical to human resource quality because nutrition is a source of future growth, cognitive development, academic performance, and productivity. Nutrition education is one of the efforts to promote a healthy diet for life and should be started as early as possible. This community service activity aims to increase the understanding and awareness of school-age children regarding balanced nutrition. This activity was carried out at the Sobyor Nature School, Tulungrejo Village, Bumiaji District, Batu City, East Java. The results of the activity showed an increase in the knowledge score of the participants after health education was carried out using the method of lectures, discussions, and puzzle games. More community service activities involving parents and schools are expected to expand health education efforts.
EFFECT OF PHYTOESTROGENS IN COWPEA (Vigna unguiculata) ON BREAST CANCER IN MENOPAUSE Hermawan Wibisono; Nina Rini Suprobo
Indonesian Journal of Health Care Management Vol 3, No 1 (2022): Indonesian Journal Health Care Management
Publisher : STIKes Kepanjen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36053/ijohcm.v3i1.28

Abstract

Perimenopausal or early postmenopausal women can be prescribed Hormone Replacement Therapy to help them manage moderate to severe menopausal symptoms. One of the primary concerns is that Hormone Replacement Therapy may escalate breast cancer risk. Natural polyphenols' anticancer properties are now a popular issue in many research labs over the last two decades. Polyphenols may be useful in the development of anticancer drugs. Cowpea (Vigna unguiculata) contains a high concentration of flavonoids, phenolic compounds, and antioxidants. Phytoestrogens can bind to mammalian ER and act as inadequate aromatase inhibitors, that might lower the breast cancer risk through limiting circulating estrogen levels.
Balanced Nutrition Education in School-Age Children: A Community Service Rizqie Putri Novembriani; Nina Rini Suprobo; Elisa Danik Kurniawati; Winny Kirana Hasanah
Indonesian Journal of Health Care Management Vol 3, No 1 (2022): Indonesian Journal Health Care Management
Publisher : STIKes Kepanjen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36053/ijohcm.v3i1.34

Abstract

Investing in child nutrition is critical to human resource quality because nutrition is a source of future growth, cognitive development, academic performance, and productivity. Nutrition education is one of the efforts to promote a healthy diet for life and should be started as early as possible. This community service activity aims to increase the understanding and awareness of school-age children regarding balanced nutrition. This activity was carried out at the Sobyor Nature School, Tulungrejo Village, Bumiaji District, Batu City, East Java. The results of the activity showed an increase in the knowledge score of the participants after health education was carried out using the method of lectures, discussions, and puzzle games. More community service activities involving parents and schools are expected to expand health education efforts.
Edukasi Perubahan Masa Pubertas dan Upaya Perlindungan Diri untuk Pencegahan Kekerasan Seksual pada Anak Elisa Danik Kurniawati; Rizqie Putri Novembriani; Nina Rini Suprobo; Winny Kirana Hasanah
Genitri: Jurnal Pengabdian Masyarakat Bidang Kesehatan Vol 1 No 2 (2022): Desember
Publisher : Politeknik Kesehatan Kartini Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36049/genitri.v1i2.86

Abstract

Pendidikan seks pada anak yang masih dianggap tabu berdampak pada tingginya kasus kekerasan maupun pelecehan seksual pada anak. Beberapa kasus kekerasan seksual yang terjadi pada anak telah diidentifikasi bahwa anak tidak tahu dan tidak menyadari tindakan yang dilakukan oleh pelaku kekerasan seksual merupakan tindakan yang salah. Maka dari itu, pendidikan seks penting diberikan pada anak usia sekolah. Kegiatan pengabdian masyarakat yang dilakukan adalah pemberian edukasi mengenai perubahan masa pubertas dan upya perlindungan diri untuk pencegahan kekerasan seksual pada anak. Metode edukasi yang digunakan yaitu Small Group Discussion (SGD) dan video (audiovisual). Hasil pre-test menunjukkan hanya terdapat 15% anak yang mengetahui perubahan masa pubertas dan upaya perlindungan diri untuk mencegah kekerasan seksual. Proses SGD dilakukan sesuai langkah dan diskusi berjalan sesuai dengan tujuan yang ingin dicapai. Ketka pemaparan video, siswa memperhatikan dengan seksama. Hasil post-test menunjukkan bahwa 70% siswa telah mengetahui perubahan masa pubertas dan upaya perlindungan diri untuk mencegah kekerasan seksual.