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All Journal JKM (Jurnal Kebidanan Malahayati) Asian Journal of Health Research
Maharani Maharani
Department of Midwifery, Polytechnic of Health-Ministry of Health, Aceh, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Black-Eyed Pea Diet Alleviates High-Density Lipoprotein Cholesterol In Menopausal Women; Randomized Clinical Trial Study Handi Wiradharma; Pande Made Dwijasa; Maharani Maharani
Asian Journal of Health Research Vol. 1 No. 1 (2022): Volume 1 No 1 (April) 2022
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (998.583 KB) | DOI: 10.55561/ajhr.v1i1.12

Abstract

Introduction: Menopause is defined as the last menstruation cycle in women. Estrogen concentration in menopausal women was decreased and altered the lipid metabolism profiles. Menopausal women reportedly have a high risk of cardiovascular disease, arthritis, diabetes mellitus, and stroke. This study focused on the effect of the black-eyed pea diet on the lipid profiles in menopausal women. Material and Methods: A randomized clinical study was performed to analyzedd the effect of the black-eyed pea diet on lipid profiles. Fifty-four menopausal women were selected as respondents and classified into two groups, black-eyed pea diet and placebo. Black-eyed pea diet treatment was performed by consuming black-eyed powder containing 67.5 mg of isoflavones and were monitored in week – 0 and week – 12 after treatment. Lipid profile of black-eyed pea diet and placebo in 12 weeks monitoring showed no significant value. After 12 weeks of treatment, total cholesterol and triglyceride were higher than before treatment. Results: Interestingly, the black-eyed pea diet increased the HDL and lowered the LDL after 12 weeks of treatment. Conclusion: This study concluded that black-eyed pea improved lipid profile, especially in elevating HDL level and decreasing LDL level in 12 weeks consumption.
Literature Review: The Effect Of Giving Purple Sweet Potato On Haemoglobin (Hb) Levels Maharani Maharani; Ardina Rezky Noeraini
JKM (Jurnal Kebidanan Malahayati) Vol 9, No 2 (2023): Volume 9 No.2 April 2023
Publisher : Program Studi Kebidanan Fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkm.v9i2.9407

Abstract

Latar Belakang: Angka kejadian anemia pada ibu hamil sekitar 38,2 juta jiwa di dunia, sedangkan di Asia tenggara terdapat 11,5 juta ibu hamil yang mengalami anemia. Prevalensi anemia pada ibu hamil di Indonesia mengalami peningkatan yaitu pada tahun 2013 sebanyak 37,1% meningkat menjadi 48,9% pada tahun 2018. Untuk menangani kejadian anemia saat hamil, ibu dapat mengkonsumsi makanan yang mengandung zat besi salah satunya ubi jalar ungu, setiap 100 gr mengandung 0,7 mg zat besi.Tujuan: Untuk melakukan review pada beberapa literatur terkait pengaruh ubi jalar terhadap perubahan kadar Haemoglobin (Hb) pada ibu hamil dengan Anemia.Metode: Penelitian ini menggunakan studi literature review yang mengkaji pengaruh ubi jalar terhadap kadar Hb. Penelitian ini menggunakan data sekunder berupa artikel sebanyak empat artikel yang kemudian direview. Pengumpulan data menggunakan metode dokumentasi. Sumber Jurnal yang digunakan diperoleh dari Google Scholar dan Blossom Journal of Midwifery. Analisis data dilakukan dengan tiga tahap, yaitu kompilasi, analisis dan simpulan yang sesuai dengan rumusan dalam penelitian ini.Hasil: Hasil penelitian menunjukkan bahwa tiga artikel signifikan menunjukkan ubi jalar berpengaruh terhadap kadar Hb dan satu artikel pada ibu dengan menggunakkan air rebusan daun ubi jalar.Kesimpulan: Empat artikel yang direview, tiga diantaranya menunjukkan perubahan yang signifikan terhadap kadar Hb setelah di intervensi dengan ubi jalar.Saran: Peneliti berharap agar ibu hamil bisa memanfaatkan manfaat ubi jalar untuk memperbaiki kadar Hb terutama bagi ibu hamil dengan anemia. Kata kunci: Anemia, Kadar Hb,Ubi Jalar ABSTRACT Background: Anemia in pregnant women affects approximately 38.2 million women worldwide, with 11.5 million pregnant women suffering from anemia in Southeast Asia. The prevalence of anemia in pregnant women in Indonesia has increased from 37.1% in 2013 to 48.9% in 2018. To deal with the incidence of anemia during pregnancy, mothers can consume foods that contain iron, one of which is purple sweet potato, in which every 100 grams contains 0.7 mg of iron.Purpose: To review some of the literature related to the effect of sweet potatoes on changes in hemoglobin (Hb) levels in pregnant women with anemia.Methods: This study used a literature review to examine the effect of sweet potatoes on Hb levels. This study uses secondary data in the form of four articles, which are then reviewed. Data collection uses the documentation method. Journal sources used were obtained from Google Scholar and the Blossom Journal of Midwifery. Data analysis was carried out in three stages, namely compilation, analysis, and conclusions according to the formulation in this research.Results: The result showed that three significant articles showed that sweet potatoes had an effect on Hb levels, and one article focused on mothers using sweet potato leaf-boiled water.Conclusion: Conclusion in this study four articles were reviewed, three of which showed significant changes in Hb levels after intervention with sweet potatoes.Suggestions: Researchers hope that pregnant women can take advantage of the benefits of sweet potatoes to improve Hb levels, especially for pregnant women with anemia. Keyword: Anemia, Haemoglobin Levels, Sweet Potato
Hepatotoxicity Oral Administration of Flavonoids Rich Extract from Phaleria Macrocarpha in Mice Siskanita Fitriana; Sri Andarini; Sutrisno Sutrisno; Gita Nawangtantrini; Maharani Maharani
Asian Journal of Health Research Vol. 2 No. 2 (2023): Volume 2 No 2 (August) 2023
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v2i2.109

Abstract

Introduction : Herbal medications are increasingly being used to treat a wide range of illnesses. Phaleria macrocarpa, often known as the crown of the gods, is a plant rich in flavonoids that is frequently used in herbal therapy. The goal of this study was to see what effect a flavonoid-rich extract from phaleria macrocarpa has on the livers of mice. Material and Methode : This study used adult female mice aged 6-8 weeks and weighing 20-30 gr as experimental animals, which were divided into four groups: the control group was given distilled water, group 2 was given a flavonoid dose of 500 mg/kg/day, group 3 was given a flavonoid dose of 1000 mg/kg/day, and group 4 was given a flavonoid dose of 2000 mg/kg/day. The flavonoid-rich extract of Phaleria macrocarpa was administered for 28 days. On the 29th day, the mice were necropsied, followed by surgery and examination of the mice's livers. Result : The flavonoid-rich extract of phaleria macrocarpa at a dose of 500 mg/kg body weight/day resulted in no changes in the weight or histological structure of the liver (p>0.05). Hydropic degeneration and necrosis were observed in the group administered the flavonoid-rich extract of phaleria macrocarpa at doses of 1000 and 2000 mg/kg body weight/day. Conclusion : The administration of a flavonoid-rich extract from Phaleria macrocarpa at a level of 500 mg/kg body weight/day caused no harm in the liver of mice. The use of more than 500 mg/kg body weight/day over an extended period of time has hazardous effects and is not recommended.
Co-Authors Ardina Rezky Noeraini Gita Nawangtantrini Handi Wiradharma Pande Made Dwijasa Siskanita Fitriana Sri Andarini Sutrisno Sutrisno