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All Journal Denta: Jurnal Kedokteran Gigi
Widaningsih
Prostodonsia Fakultas Kedokteran Gigi Universitas Hang Tuah
Dentistry

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Pengaruh Pemberian Ibuprofen Preoperatif Terhadap Sebaran Sel Radang Kronis Pada Proses Penyembuhan Luka Pasca Pencabutan Gigi Fanny Marisca Alviony; Eddy Hermanto; Widaningsih
Denta Journal Kedokteran Gigi Vol 10 No 1 (2016): Februari
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

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Background: Wound is destruction of part of the body's tissues caused by agent like germs, parasites, fungi, sharp force trauma, temperature changes, chemicals, electric shock. Inflammatory phase in the process of wound healing has very important role. In the chronic inflammation there are chronic inflammatory cell infiltration, namely macrophages, lymphocytes, plasma cells, eosinophils, mast cells, basophils accompanied by the proliferation of blood vessels and fibrosis. Ibuprofen is anti-inflammatory and analgesic drugs that usually given after tooth extraction. Purpose: This study was aimed to examine the effect of preoperative ibuprofen against the spread of chronic inflammatory cells in the process of wound healing after tooth extraction. Materials and Methods: The experimental unit used were 20 male Wistar rats divided into two groups, group1 (NaCMC 0.2%), group2 (Ibuprofen 7,2mg / 200grBB). NaCMC 0.2% for the group K and Ibuprofen for group X given 1 hour before incisor tooth extraction and then the bottom left tooth of mice were be lifted. The Socket were then sutured and left up to 7 days. Data were analyzed by Chi-Square test. Results: Chi-Square test showed significant difference between group K and X p = 0.003 (p <0.05). Conclusion: Preoperative administration of ibuprofen were lower the spread of chronic inflammatory cells in the process of wound healing after tooth extraction.
The Difference Compressive Strength of Scaffold Combination Chitosan and Aloe vera Extracted Water and Ethanol Dwi Ayu Trisnawati; Sularsih; Widaningsih
Denta Journal Kedokteran Gigi Vol 13 No 1 (2019): Februari
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

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Background: Scaffold can be use in bone regeneration, but it should have similarities characteristic to a natural bone such as compressive strength that supported the process of growth and development of bone. This research use scaffold that made from chitosan and Aloe vera. Chitosan well-known as osteoconductive material, meanwhile Aloe vera was osteoinductive material. Purpose: The aim of this research was to compare compressive strength scaffold combinations of chitosan and Aloe vera extracted water and ethanol. Materials and Methods: Research design using post test only control group design with 36 scaffolds divided into 6 groups. Group 1 was scaffold Aloe vera extracted water (AVa), group 2 was scaffold Aloe vera extracted ethanol (AVe), group 3 was scaffold combination chitosan and Aloe vera extracted water 1: 1 (k-AVa1), group 4 was the scaffold combination of chitosan and Aloe vera extracted ethanol 1: 1 (k-AVe1), group 5 was scaffold combination of chitosan and Aloe vera extracted water 1: 2 (k-AVa2), and group 6 was scaffold combination of chitosan and Aloe vera ethanol extract 1: 2 (k -AVe2). Compressive strength test used Universal Testing Machine (Shimadzu Autograph–AGS–1kNX and using software Trapezium X). Data were analyzed using One Way ANOVA and Games Howell test. Results: The result of compressive strength AVa=1.36 MPa, AVe=1.03 MPa, k-AVa1=0.27 MPa, k-AVe1=0.11 MPa, k-AVa2=0.38 MPa, and k-AVe2=0.29 MPa. All groups have significant differences except AVa & AVe and k-AVa1 & K-AVe2 (p>0,05). Conclusion: There was difference between compressive strength scaffold combinations of chitosan and Aloe vera extracted water and ethanol, and the most highest compressive strength is AVa.
The Difference of Impact Strength in Acrylic Resin Self-Cured with the Addition of Zirconium Dioxide (ZrO2) Nanoparticles Annete Juwita; Widaningsih; Puguh Bayu Prabowo
Denta Journal Kedokteran Gigi Vol 12 No 1 (2018): Februari
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

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Background: Self-cured acrylic resin is a material used for repairing broken and fractured dentures. Zirconium dioxide (ZrO2) is a reinforcing material that is being developed as an additive to the acrylic resin. Purpose: to determine the effect of zirconium dioxide (ZrO2) addition on self-cured acrylic resin on impact strength. Material and Methods: This study was a true experimental laboratory study with the design of a post-test only control group design, using 24 pieces of self-cured acrylic resin measuring 65 x 10 x 2.5 mm divided into 4 groups with and without zirconium addition dioxide (ZrO2) nanoparticles. Zirconium dioxide (ZrO2) nanoparticles were silanized first by mixing the silane coupling agent. Furthermore, the impact strength was tested on the plate. The data obtained were analyzed using the One Way ANOVA test. Results: there were significant differences in the impact strength between the groups with a significance value of 0,000 (p <0.05). Conclusion: there was a difference in the increase of impact strength in acrylic resin self-cured with the addition of ZrO2 nanoparticles concentrations of 3%, 5%, and 7%.
Co-Authors Annete Juwita Dwi Ayu Trisnawati Eddy Hermanto Fanny Marisca Alviony Puguh Bayu Prabowo Sularsih Sularsih