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All Journal The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy

Sahat Halim, Sahat

Division of Gastroentero-hepatology, Department of Internal Medicine Faculty of Medicine, University of Sumatra Utara/Adam Malik General Hospital, Medan

Author-ID : 548502

Health Professions Medicine & Pharmacology

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Articles

Dyspepsia and Depression, Anxiety, Stress Scales (DASS) Score Siregar, Gontar Alamsyah; Halim, Sahat; Sitepu, Ricky Rivalino
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 17, No 1 (2016): VOLUME 17, NUMBER 1, April 2016
Publisher : The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy

Background: Dyspepsia is a constellation of symptoms referable to the gastroduodenal region of the upper gastrointestinal tract. Emotional disturbances are often associated with dyspepsia and have been proposed as one of the possible causes of dyspepsia. This study was aimed to evaluate the difference between the severity of dyspepsia using porto alegre dyspeptic symptoms questionnaire (PADYQ) and emotional disturbances using depression, anxiety, stress scales (DASS).Method: This study was a cross-sectional analytical study. All the subjects were evaluated using PADYQ and DASS. PADYQ is classified into four categories (no, mild, moderate and severe dyspepsia symptoms). Data was analyzed using Independent t-test and Mann-Whitney test. A p < 0.05 was considered as statistically significant.Results: There were 90 subjects that enrolled in this study, consisted of 47 (52.2%) males and 43 (47.8%) females. Thirty three (36.7%) subjects had PADYQ score was < 6, while it was ≥ 6 in the other 57 (63.3%) subjects. DASS scores were significantly different in subjects without dyspepsia symptoms compared to subjects with dyspepsia symptoms. There is a difference in DASS scores between subjects with different categories of dyspepsia symptoms (p < 0.05). Conclusion: There was a difference in the severity of emotional disturbances among subjects with dyspepsia symptoms and without dyspepsia symptoms. The severity of emotional disturbances parallel with the severity of dyspepsia. Evaluation of emotional disturbances in case of dyspepsia will be helpful in the management of dyspepsia.

Infection and Colorectal Neoplasm Siregar, Gontar Alamsyah; Halim, Sahat; Sitepu, Ricky Rivalino
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 16, No 1 (2015): VOLUME 16, NUMBER 1, April 2015
Publisher : The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy

Colorectal cancer is a major cause of cancer-related morbidity and mortality. Colorectal cancer is the third most common malignancy and the 4th most common cause of cancer mortality worldwide. A number of infectious agents are considered to be cancer risk factors due to the hypothesis-generating and supportive evidence accumulated to date. It has been estimated that one fifth of all cancer is caused by some infectious agent(s). Infections from certain bacteria, such as Helicobacter pylori (H. pylori), Streptococcus bovis (S. Bovis), viruses, such as human papillomavirus (HPV), human cytomegalovirus (HCMV), and parasites may increase the risk of colorectal cancer. More studies are needed to learn the association of infectious agents with the incidence of colorectal cancer.Keywords: colorectal cancer, infectious agents, malignancy, neoplasms

Correlation between Severity of Dyspepsia and Helicobacter pylori Infection Siregar, Gontar Alamsyah; Halim, Sahat
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 15, No 1 (2014): VOLUME 15, NUMBER 1, April 2014
Publisher : The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy

Background: Dyspepsia is a common complaint in clinical practice. Correlation between Helicobacterpylori (H. pylori) and functional dyspepsia had been reported in many studies, but studies that analyzed theseverity of dyspepsia and H. pylori were limited and the results were controversial. This study is about to knowthe correlation between the severity of dyspepsia and H. pylori infection. Method: A retrospective descriptive analysis to patients with dyspepsia at Permata Bunda Hospital, Medan was done in 2010-2014. Simple random sampling was done to get 44 patients with dyspepsia, 22 are H. pylori positive and 22 patients are H. pylori negative. The severity of dyspepsia assessed with Porto Alegre DyspepticSymptoms Questionnaire (PADYQ) scoring instrument. Univariate and bivariate analysis (Chi-square andSpearman correlation) were done using SPSS version 22. Results: Epigastric pain is the most common symptom in dyspepsia patients. There is a correlation betweenulcer type dyspepsia and H. pylori infection (p = 0.030), while dysmotility type and mixed type were not correlated.The severity of epigastric pain has significant positive correlation with H. pylori (r = 0.386; p = 0.01), while theseverity of other symptoms such as nausea, vomit, and abdominal bloating have negative correlation with H.pylori. Dyspepsia total scoring is significantly lower in H. pylori positive than in H. pylori negative (p = 0.033). Conclusion: There is a positive correlation between the severity of epigastric pain and H. pylori infection,negative correlation between the severity of nausea, vomit, and abdominal bloating and H. pylori infection, andcorrelation between lower dyspepsia total scoring and H. pylori infection.Keywords: dyspepsia, Helicobacter pylori, PADYQ, epigastric pain

Comparison of Endoscopic Findings with Gastroesophageal Reflux Disease Questionnaires (GerdQ) and Reflux Disease Questionnaire (RDQ) for Gastroesophageal Reflux Disease in Medan Siregar, Gontar Alamsyah; Halim, Sahat; Sitepu, Ricky Rivalino
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 16, No 3 (2015): VOLUME 16, NUMBER 3, December 2015
Publisher : The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy

Background: There are many questionnaires that have been developed to diagnose gastroesophageal reflux disease (GERD), i.e. reflux disease questionnaire (RDQ), and the recently developed, gastroesophageal reflux disease questionnaires (GerdQ). In this study, we tried to compare GerdQ and RDQ in terms of sensitivity and specificity to diagnose GERD and its relationship with endoscopic findings.Method: This study was a cross sectional analytical study. Subsequently, all the subjects were evaluated using the GerdQ and RDQ, then underwent esophagogastroduodenoscopy examination. The severity of endoscopically observed reflux esophagitis was graded with the Los Angeles classiﬁcation. All endoscopy was performed by well-trained doctor.Results: A total of 85 patients were examined, 34 (40%) patients had reflux esophagitis at endoscopy examination, including 15 (44.1%) cases of grade A, 11 (32.3%) cases of grade B, 4 (11.8%) cases of grade C, and 4 (11.8%) cases of grade D. Analysis study using sensitivity, specificity, and receiver operating characteristic (ROC) test showed that GerdQ had sensitivity (49%), specificity (91%), and an area under the ROC of 0.701 (p value = 0.002). RDQ had sensitivity (24%), specificity (91%), and an area under the ROC of 0.574 (p value = 0.253). Taking 11 as the cut off point for GerdQ, a maximal sensitivity of 73.5%, specificity of 82.4%, and an area under the ROC of 0.779 was achieved.Conclusion: GerdQ and RDQ can be used to help diagnose GERD, but GerdQ is more superior than RDQ in diagnosing GERD. A multi-center study with larger samples is needed to determine the best GerdQ’s cut off point in Indonesia.

Co-Authors Gontar A Siregar, Gontar A Gontar Alamsyah Siregar Ricky R Sitepu, Ricky R Ricky Rivalino Sitepu, Ricky Rivalino

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