Suci Hanifah
Department Of Pharmacy, Universitas Islam Indonesia

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Analisis Kualitas Hidup Pasien Asma di Balai Pengobatan Penyakit Paru-Paru (BP4) Sari, Chynthia Pradiftha; Saepudin, Saepudin; Hanifah, Suci
JURNAL PHARMASCIENCE Vol 1, No 2 (2014): JURNAL PHARMASCIENCE
Publisher : JURNAL PHARMASCIENCE

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Abstrak             Pengobatan yang diperoleh pasien asma tidak selamanya dapat memulihkan kondisi asma yang dialami. Biaya pengobatan yang dapat dikatakan tidak murah menyebabkan tidak semua pasien asma dapat menjangkau biaya pengobatan, sehingga pasien mengalami keterbatasan dalam beraktivitas serta meningkatnya frekuensi kekambuhan yang akan mempengaruhi kualitas hidup pasien asma. Penelitian ini bertujuan untuk mengetahui gambaran kualitas hidup pasien asma dan pengaruh terapi yang digunakan terhadap kualitas hidup pasien di BP4 unit Minggiran Yogyakarta. Sampel penelitian ini adalah pasien dewasa dengan diagnosa asma tanpa penyakit penyerta. Metode penelitian ini menggunakan metode cross sectional yang bersifat observatif, dari hasil wawancara serta pengisian Asthma Quality of Life Quessioner (AQLQ). Analisis data meliputi data kualitas hidup, terapi obat yang digunakan dan faktor-faktor yang mempengaruhi kualitas hidup pasien asma. Hasil analisis kualitas hidup diolah dalam bentuk persentase dan disajikan dalam bentuk tabel. Hasil penelitian pada pasien dewasa di BP4 unit Minggiran Yogyakarta menunjukkan, sekitar 82,2% pasien memiliki kualitas hidup baik dan 17,8% pasien dengan kualitas hidup kurang baik. Berdasarkan hasil uji chi-square terapi antiasma yang digunakan berpengaruh terhadap kualitas hidup pasien asma. Kata kunci: asma, kualitas hidup,  chi-square, BP4 unit Minggiran Yogyakarta Abstract Obtained treatment of asthma patients are not always able to restore the condition of asthma is experienced. The cost of treatment that can be said is not cheap cause not all asthma patients can reach medical expenses, so that patients have limitations in activity and an increase in the frequency of recurrence that will affect the quality of life of asthma patients. This study aims to describe the quality of life of asthma patients and the effect of therapy that is used for quality of life patients asthma in BP4 unit Minggiran Yogyakarta. Samples were adult patients with a diagnosis of asthma without concomitant diseases. This research method using cross sectional observational, from interviews as well as charging the Asthma Quality of Life Quessioner (AQLQ). Data analysis included the data quality of life, therapeutic drugs used and the factors that affect the quality of life of asthma patients. The results of the analysis of the quality of life in the form of a percentage processed and presented in tabular form. The results of the study in adult, BP4 unit Minggiran Yogyakarta shows, approximately 82.2% of patients have a good quality of life and 17.8% of patients with a poor quality of life. Based on the results of chi-square test antiasma therapy is used to influence the quality of life of patients asthma.  Key words: asthma, quality of life, BP4 Minggiran unit Yogyakarta, logistic regression.
Penerapan Kartu Pintar Fisiologi Manusia dalam Metode Pembelajaran Cooperative Learning Mutiara Herawati; Suci Hanifah
Majalah Farmasetika Vol. 4, Supl. 1, Tahun 2019
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v4i0.25862

Abstract

Semulametodepembelajaranberpusat pada dosen (Teacher Centre Learning), namunkinimetodepembelajaran mulai diubahmenjadiberpusat pada siswa (SCL/Student Centre Learning) yang mana keduanyamemilikikeuntungandankekuranganmasing-masing. Metodepembelajarancooperative learning dengan penerapanjigsawdiharapkan dapat meningkatkanaspekkognitif, psikomotordanafektif mahasiswa. segalaaktivitaspembelajarandidominasiolehketerlibatan mahasiswa didalamnya. Penelitian ini bertujuan untuk mengetahuipenerapankartupintarfisiologimanusia dalam metodepembelajaranCooperative Learning sehingga dapat meningkatkanmotivasidanstrategi dalam belajar mahasiswa, pemahaman mahasiswa sertakelulusan dengan nilai ≥ C mahasiswa. Proses pembelajarandimodifikasi dengan penggunaangoogle classroom untuk meningkatkanpemahaman mahasiswa selama menerima materi. Digunakan pula kuesionerMotivated Strategies for Learning Questionnaire (MSLQ) yang merupakanalatukur mandiri yang digunakan untuk mengetahuiorientasimotivasi mahasiswa dalam belajar dan dapat digunakan untuk mengetahuistrategi mahasiswa dalam belajar. Berdasarkan daripertanyaankuesionerdidapatkannilai rata-rata diatas 3 (skalamaksimal 4) yang artinyabahwametodepembelajaran yang diterapkan pada mahasiswa membuat mahasiswa memilikikemampuan untuk diskusi, mencapaitujuanpembelajaran, menstimulasi mahasiswa untuk belajar danmeningkatkanminatsertapemahaman dalam mempelajarimata kuliah fisiologimanusia. Disamping itu, diketahuibahwakelompokperlakuan 62,15 memilikinilai paling tinggidibandingkan dengan kelompokkontrol 59.75 sertameningkatkankelulusan mahasiswa fisiologimanusiadaribaseline 50% menjadi 60%. Metodepembelajaran ini efektifmeningkatkannilai rata-rata akhir.
POLA PENGGUNAAN OBAT UNTUK PENDERITAGAGAL GINJAL AKUT DI INSTALASI RAWAT INAP RUMAH SAKIT UMUM PUSAT (RSUP) DR. SARDJITO YOGYAKARTA TAHUN 1997-2001 Suci Hanifah
Jurnal Ilmiah Farmasi Vol. 1 No. 1 (2004)
Publisher : Universitas Islam Indonesia

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ABSTRACTDrug Utility Review for ARF’ patients of Internal Unit, Sardjito’s hospital was examed. Itinvolved 109 ARF’s patients. Medical Record Unit reported that this number was 0,12% of alldisese i.e. 93.445 case in 2001. The level was 93rdfrom 945 kind of disease. It was studied bynonanalitical descriptive design. using notes of Medical Record system. Collecting of data byretrospektive methode. This research was aimed to study the Drug Utility Review for ARF’spatients, especially to study ; drug variation included kind and class of drugs, route ofadministration, variation drug number, length of stay, and regimen dosage of drugs. To complete it,mortality persentaged was reported. The result of the study showed that ARF’s patients got somany variation of drugs. Using of antibiotic, diuretic, and electrolit was the most case. It conformedto Health Care Standard in Sardjito’s hospital. The others was aimed to simptomatical drugs i.e.antihypertensi, cardioasculer drugs, analgetic, antiemetic, multivitamin, laxan etc. It depended onsymptoms and complication of patients. Variation of number between 1-24. The average numberwas 7,7 drugs. It tended to use new generation of antibiotic and combinatins antibiotic, as indicatorof extravagant prescibing. Route of administratin by orally in most case and 38 % by injection.Injection route so indicate extravagant prescibing except on emergency care. The others used bysublingual and suppositoria. Length of stay averaged 12,52 days. Mortality persentaged was 22%.Key words : Drug Utility Review, ARF, Medical Record,Extravagant Prescribing
POTENSI KEJADIAN INTERAKSI OBAT PADA PENGGUNAAN OBAT UNTUK PASIEN ANAK YANG DIRAWAT INAP DENGAN DIAGNOSA INFEKSI SALURAN PERNAFASAN DI SALAH SATU RUMAH SAKIT SWASTA DI SURAKARTA Saepudin Saepudin; Suci Hanifah; Wachidah Rahmawati
Jurnal Ilmiah Farmasi Vol. 3 No. 1 (2006)
Publisher : Universitas Islam Indonesia

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ABSTRACTThis research was aimed at knowing potential drug interactions on drug prescribing fortreatment of hospitalized pediatric patients with respiratory tract infection. Research was carriedout at a private hospital in Surakarta and data were collected from medical records of patients werehospitalized during January – December 2005. Potential drug interactions were determinedtheoretically using some literatures on drug interaction. From total 186 patients included in thisresearch, 67.2% were 0-4 years old with common cold was the most diagnosed. There were 52.7%patients receiving 4-6 item of drugs and 76.9% patients were hospitalized during 1-3 days.Potential drug interactions were identified in 30.7% patients with 1.8% and 15.8% of them at level 1and 2 clinical significance, respectively. Statistically, there was a relationship between potentialdrug interactions and length of hospitalization (p = 0.001). Some further investigations(prospectively) are needed to ensure results from this research.Key words : drug interaction, respiratory tract infection, pediatric
HEPATOTOKSISITAS PADA PENGOBATAN TUBERKULOSIS DI RSUD TANGERANG – INDONESIA Vitarani Dwi Ananda Ningrum; Arnia Megasari,; Suci Hanifah
Jurnal Ilmiah Farmasi Vol. 7 No. 1 (2010)
Publisher : Universitas Islam Indonesia

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Reaksi obat yang tidak dikehendaki atau yang dikenal dengan ADR (Adverse Drug Reaction) merupakan respon pasien terhadap obat yang berbahaya dan tidak diharapkan yang terjadi pada penggunaan obat dengan dosis normal untuk tujuan profilaksis, diagnosis, terapi suatu penyakit, maupun modifikasi fungsi fisiologis. Obat yang telah diketahui dapat menimbulkan hepatotoksisitas atau kerusakan fungsi hepar adalah golongan antimikobakteri yang digunakan dalam pengobatan tuberkulosis (TB) paru. Pasien tuberkulosis harus menggunakan obat secara teratur sampai periode pengobatan selesai. Penggunaan OAT (Obat Antituberkulosis) secara terus menerus dalam jangka waktu yang cukup lama dapat menimbulkan ADR. Penelitian ini bertujuan untuk mengetahui kejadian hepatotoksisitas pada pasien tuberkulosis paru serta faktor-faktor yang mempengaruhi terjadinya hepatotoksisitas. Metode penelitian dilakukan dengan menggunakan rancangan studi cross sectional. Pasien yang dilibatkan dalam penelitian ini adalah pasien yang mendapatkan regimen terapi antituberkulosis di RSUD Tangerang pada periode 2006 - Februari 2009. Penilaian kejadian hepatotoksisitas berdasarkan adanya peningkatan kadar AST/ALT serum. Hasil penelitian dari 55 pasien menunjukkan bahwa kejadian hepatotoksik sebesar 38,2%. Hasil uji statistik menggunakan analisis Regresi Binary Logistik dengan taraf kepercayaan 95% menunjukkan jenis kelamin laki-laki dan penggunaan obat hepatotoksis lain memiliki pengaruh terhadap kejadian hepatotoksik. Selain itu terdapat faktor yang dapat mengurangi kejadian hepatotoksik diantaranya penghentian obat, penggantian obat, dan pemberian curcumin. 
Variabilitas konsentrasi pada pemberian obat-obat infus: studi kasus di Pediatric Intensive Care Unit (PICU) Suci Hanifah
Jurnal Ilmiah Farmasi Vol. 13 No. 2 (2017): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol13.iss2.art2

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Latar belakang: Studi penggunaan obat di PICU menunjukkan tingkat kesalahan paling banyak pada tahap penyiapan dan pemberian obat, yang berakibat pada terjadinya variasi kadar obat. Salah satu faktornya adalah teknik pencampuran dan pemberian multi-infus.Tujuan: Penelitian ini bertujuan untuk mengetahui variabilitas kadar obat pada teknik pencampuran manual dan pemberian multi-infus seperti yang biasa dikerjakan di PICU rumah sakit.Metode: Uji homogenitas dilakukan dengan mengukur kadar obat midazolam, dobutamin, dan norepinefrin setelah direkonstitusi dengan glukosa 5% dalam spuit 50 mL secara manual sebanyak lima kali penggojokan. Variasi kadar obat pada multi-infus dievaluasi dengan membandingkan sistem infus menggunakan satu pompa dan sistem multi-infus (tiga pompa) yang diparalel.Hasil: Pencampuran secara manual memberikan variasi konsentrasi yang besar (%RSD >10%, p-value<0,05). Sementara itu, variasi konsentrasi pada pencampuran dengan sonikasi rendah (%RSD <10%, p-value >0,05).Kesimpulan: Hasil penelitian ini menyimpulkan bahwa pencampuran secara manual dengan lima kali penggojokan tidak cukup memberikan homogenitas yang baik. Sementara itu, pemberian obat dalam tiga pompa infus paralel memberikan variasi yang masih diterima secara statistik (%RSD <0,10, p-value >0,05).Kata kunci: variabilitas, konsentrasi obat, homogenisasi, infus bercabang
IDENTIFIKASI pH OBAT-OBAT YANG DIGUNAKAN DI PEDIATRIC INTENSIVE CARE UNIT (PICU) UNTUK PENCEGAHAN INKOMPATIBILITAS INTRAVENA Suci Hanifah
Jurnal Ilmiah Farmasi Vol. 11 No. 2 (2015): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

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Intisari Pasien anak-anak di unit perawatan intensif sering mendapatkan banyak obat dalam satu jalur infus. Presipitasi akibat perbedaan pH obat-obat yang bertemu i jalur intravena cenderung terjadi secara cepat sehingga menimbulkan masalah di jalur infus. Oleh karena itu, data pH sangat penting bagi praktisi untuk membuat panduan dalam menentukan jenis jalur yang tepat sehingga inkompatibilitas tidak terjadi. Penelitian ini bertujuan  untuk mengidentifikasi obat-obat yang sering digunakan di PICU dan mengukur pH dari obat-obat yang umum digunakan di ICU. Data obat dikumpulkan dari dokumen logistic farmasi selama tahun 2013. Keempat puluh obat injeksi yang siap diberikan, diuji nilai pHnya dengan pH meter. Berdasarkan nilai pH yang diperoleh, potensi inkompatibilitas banyak terjadi pada obat-obat pH asam seperti kardiotonik dan antikolinergik dan obat-obat yang memiliki pH tinggi (basa) misalnya misalnya Asiklovir, Ampisilin, Ampi-Sulbaktam, Fenobarbital, Fenitoin, Furosemid, dan Omeprazo. Berdasarkan hasil identifikasi pH masing-masing obat, untuk mencegah inkompatibilitas, sedikitnya diperlukan tiga jalur; jalur obat asam, jalur obat basa, dan jalur khusus. Jalur yang spesifik digunakan untuk cairan yang cenderung tidak bisa melalui jalur asam maupun basa, karena hiperosmolar atau sulit larut misalnya mannitol dan diazepam.  Kata Kunci : pH, intravena, pediatric intensive care unit, inkompatibilitas
Efektivitas Pengobatan pada Pasien Penyakit Paru Obstruksi Kronis (PPOK) di Rumah Sakit Wilayah Yogyakarta Chynthia Pradiftha Sari; Suci Hanifah; Rosdiana Rosdiana; Yuni Anisa
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 11, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.56418

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Chronic Obstructive Pulmonary Disease (COPD) is a complex respiratory disorder that requires multiple approaches to assess treatment response, no specific therapy can stop the progression of disease cure. This study aimed to measure the response of COPD treatment in outpatients at Hospitals in Yogyakarta. The study was designed descriptive observational cross-sectional involved  COPD outpatients in July 2018 - June 2019 (N = 156). Inclusion criteria the subjects: age> 40 years, without other respiratory diseases (asthma, lung cancer), took theophylline for at least the last one month, complete the CAT questionnaire, and sign an informed consent. Data collected were characteristics of respondents, treatment profile (exacerbation, maintenance), and response therapy data. Evaluation of treatment response was measured using the COPD Assessment Test (CAT) questionnaire and classified the response into effective, quite effective, and not effective. These data were then presented in form of percentage distribution. The results showed that an exacerbation study with single bronchodilator 39.10%, and a combination of bronchodilator with other bronchodilators 60.90%, most LABA-ICS / LAMA rescue therapies (48.72%). Results of evaluation the use of LABA-ICS / LAMA / Methylxanthine (18.59%), LABA-ICS / LAMA / Methylxanthine/ Mucolytic (11.54%), LABA-ICS / LAMA / SABA / Methylxanthine / Mucolytic (9.62%) )) gave a fairly effective treatment response (CAT score ≥10-19) 50.64%, effective (CAT score <10) 47.43%, ineffective (CAT score ≥20) 1.93%.
Association between obesity and depression among women in Indonesia: A questionnaire based study Susi Ari Kristina; Nur Aini Mardea; Suci Hanifah
Journal of Global Pharma Technology Volume 12 Issue 09 (2020) Sept. 2020
Publisher : Journal of Global Pharma Technology

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Obesity is a global public health issue and the prevalence of obesity is growing worldwide every year. Studies have been performed since the early 1970s on the association between obesity and depression or other psychological disorders. In Indonesia, however, only a small number of studies have been carried out. The aim of this study was to examine whether obesity was associated with depression in a sample of women with overweight and obesity based on their BMI, anti-obesity treatment experience, and age among women in one province in Indonesia. Women aged 18 years and older who were selected from fitness centers in urban area of Yogyakarta province and self-reported BMI categorized as overweight and obese were eligible to participate. Voluntary participation in study survey was consented. A set of questionnaire consisting demographic characteristics and depression symptoms was developed and validated. Depression was assessed by the Patient Health Questionnaire-9 (PHQ-9), with a score of ≥10 used to indicate severe depression. Respondents who classified as overweight mostly had minimal depression level (33.58%) and none had severe depression level, whereas respondents who classified as obese mostly had moderate depression level (44.74%) and 3.95% had severe depression level. This study found that BMI, experience of using anti-obesity drugs, and age of respondents were significantly affected PHQ-9 score. Thus, these factors determined the level of depression among women surveyed. The study reported significant association between obesity and depression among women. This association depends on BMI, anti-obesity treatment experience, and age variables. Approaches to public health to reduce the burden of obesity or depression have to consider the strong link between these two common conditions.
Awareness of Chronic Kidney Disease among General Adult Population in Indonesia Susi Ari Kristina; Laksmy Anggun Larasati; Suci Hanifah
Journal of Global Pharma Technology Volume 12 Issue 06 (2020) June 2020
Publisher : Journal of Global Pharma Technology

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Background: Chronic kidney disease (CKD) is rapidly becoming a major problem for developing countries such as Indonesia in terms of complicated management such as hemodialysis, continuous ambulatory peritoneal dialysis (CAPD) or high-cost renal transplantation. In its initial stages, early diagnosis and management of CKD may help avoid or delay disease progression. This study aimed to assess CKD's awareness and knowledge in Indonesia's general population. Methods: Cross-sectional research design was performed among the general adult population in Yogyakarta province. Recruiting participants using a convenience sample. A pre-validated questionnaire consisted of two parts, demographic features and CKD information. A logistic bivariate regression was used to identify independent CKD predictors, and p-value