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Korelasi antara Dosis Eksposur Timbal dengan Kadar Ureum dan Kreatinin Serum pada Wistar (Rattus norvegicus) Atmawati, Baiq Jatna; Syamsun, Arfi
Jurnal Kedokteran Vol 1 No 1 (2012)
Publisher : Faculty of Medicine Universitas Mataram

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Introduction: Clean air is hard to find these days, especially in big cities where industries and motor vehicles contribute to air pollution. It is almost about 85% of air pollution is caused by the emission of motor vehicles. One of the contaminants which are produced is lead. The lead which accumulates inside the tissues of the body will cause disorder mainly to the urinarius system (kidneys), liver, hematopoetic system, cardiovascular, and reproduction system. The objective of this research is to find out the correlation between the dosage of lead exposure with the level of serum ureum and creatinine on wistar rats (Rattus norvegicus). Method: This research applies a simple experimental research design which is called the post-test only control group design. This research participates with 6 research groups, that is, 4 for the treatment groups and 2 for the control groups. On the treatment groups, firstly, wistar rats are treated in a way which they are given a gradable dosageof acetic leads per orally. The level of acetic leads given in Treatment 1 (P1) is 1.1 ml, Treatment 2 (P2) is 0.825 ml, Treatment 3 (P3) is 0.55 ml, and Treatment 4 (P4) is 0.25 ml. After 24 hours (of acute exposure), the rats are anethesized by diethyl ether and then continue take the blood through the intracardiac. On control, on the other hand, no treatment at all is given to the rats. On Control 1, previously, the rats are anethesized with diethyl ether. On Control 2, however, they are not anesthesized but do decapytation. Result: Researchers have found the result that there is no significant correlation between the dosage of lead exposure towards the level of serum ureum and creatinine on wistar rats from the experiment of Control 1 and Control 2 (p>0.05). Researchers have found that the more reduced the dosage of the acetic lead, the more increasing the average of serum ureum. As for the creatinine, researchers have seen that there is no significant difference in the value between the treatment group and control group. Researchers have also found that there is no significant difference between the level of serum ureum and the level of creatinine on control group 1 and control group 2 (p>0.05). On the other hand, it is seen that there is difference on the value of ureum and creatinine in control 1 and in control 2. Conclusion: After conducting the experiment, researchers have found the result that there is no significant correlation between the dosage of lead exposure towards the level of serum ureum and creatinine on wistar rats from the experiment of Group 1 and Group 2 (p>0.05). On the other hand, it is seen that there is difference on the value of ureum and the value of creatinine in control group 1 (anesthesized with ether) and in control group 2 (without ether).
Standarisasi Pasien dan Ruang Simulasi Meningkatkan Kepuasan Mahasiswa Kedokteran Universitas Mataram dalam Pelaksanaan Keterampilan Medik Kardiovaskuler Syamsun, Arfi; Ansyori, Maz Isa
Jurnal Kedokteran Vol 1 No 1 (2012)
Publisher : Faculty of Medicine Universitas Mataram

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Introduction: Cardiovascular diseases have high morbidity and mortality rates. Skills in administering diagnosis and treatment of the diseases is part of general physician competencies according to the Indonesian Doctors Competency Standards. The teaching of cardiovascular lab skills at the Medical Faculty of the University of Mataram has not optimally prepared standardized simulation rooms and patients. As a result, this complicates students’ clinical understanding in handling cardiovasdcular events at the hospitals and clinics with different facilities. The effectiveness of the standardization is measured from results of skill lab exams and students’ satisfaction scores. Objectives: To identify the difference in the satisfaction and skills lab scores of cardiovascular physical exam and electrocardiography (ECG) installation among students of simulation room and patient standardization groups as compared to non-standardization groups. Method: This cross sectional study involved 20 students of 5th semester of the Faculty of Medicine, Mataram University. Samples were taken randomly based on prior stratified lab skills scores. They comprised 2 treatment groups and 2 control groups as follows: group 1, simulation room and patient standardization for cardiovascular physical exam; group 2, simulation room and patient standardization for ECG examination; group 3, simulation room and patient non-standardization for cardiovascular physical exam; group 4, simulation room and patient non-standardization for ECG examination. The students then attended a Master Course, lab skills demonstration, and independent practices for 2 weeks. Satisfaction scores are measured by means of a questionnaire whose contents were validly tested, while lab skills exam scores are measured using a standard checklist issued by the Medical Faculty. Unpaired t-test is used to identify the differences in the students’ satisfaction scores and skill lab scores among the 2 groups. Study Findings: There are significant differences in the mean of students’ satisfaction scores in terms of simulation patients, lab skills room, and instructors for cardiovascular physical exam and ECG exam between the standardization and non-standardization groups. There was no significant difference in the mean of scores on communicative and eticomedicolegal competence, clinical skills competence and clinical reasoning competence on cardiovascular physical exam and ECG exam between standardization and nonstandardization groups. Conclusion: Standardization of simulation patients and rooms for cardiovascular physical exam and ECG exam significantly increases students’ satisfaction scores but does not significantly increases students’ lab skills scores. Keywords: standardization, simulation patients, simulation room, satisfaction scores, lab skills scores.
Pengaruh Pemberian Monosodium Glutamat Dosis Tinggi terhadap Kadar Serum Urea-Kreatinin pada Tikus Wistar Nisa, Hayatin; Syamsun, Arfi; Lestarini, Ima Arum
Jurnal Kedokteran Vol 2 No 1 (2013)
Publisher : Faculty of Medicine Universitas Mataram

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Background: Many cases of Monosodium Glutamate (MSG) consumption were found. Many food producers, even restaurant and household add MSG on the food produced. Safety use of MSG is still being debated. Some have claimed that the use of MSG is safe within certain limits, but the results of several studies in animals found that MSG affects the body's organs. MSG that accumulates in the body will interfere, especially the urinary system (kidneys), liver, brain, hematopoietic system, cardiovascular, central nervous system, and reproductive system. The aim of this study was to detect the effect of MSG in highrise dosage towards the level of serum urea-creatinine on Wistar Rats (Rattus novergicus). Methods: The research used a simple experimental design which iscalled the post-test only control group design. This research wasconducted on five sample groups: one group as a control, and fourothers as the treatment. The control group was not given MSG, butaquadest, while the treatment groups were given MSG solution orallyin gradable dose. MSG solution dose that was given in treatment group1 (P1) were 400 mg/100gBB, while the MSG dose for treatment 2 group(P2) were 800 mg/100gBB, treatment 3 group (P3) were 1200 mg/100gBB,and treatment 4 (P4) were 1600 mg/100gBB that were divided into 2doses. After 14 days, mice anesthetized with diethyl ether, thendecapitation and its blood was taken by intracardiac to determineserum urea-creatinine level on Wistar Rats. Result: There was significant effect of administration MSG on serum urea-creatinine levels on Wistar Rats (p <0.05). The result of this study also showed that higher doses of MSG were given, higher meanlevels of serum urea produced, while serum creatinine levels remainedrelatively constant for each group. Conclusion: There was significant effect of giving MSG on serumurea-creatinine levels on Wistar Rats statistically (p <0.05). Keywords: MSG, 14 days, Highrise Dosage, Urea, Creatinine.
HUBUNGAN ANTARA PERSEPSI PASIEN RAWAT INAP TENTANG KUALITAS PELAYANAN KESEHATAN DENGAN CITRA RUMAH SAKIT ISLAM SITI HAJAR MATARAM Hakim, Faradila Khoirun Nisa; Ekawanti, Ardiana; Syamsun, Arfi
Jurnal Kedokteran Vol 2 No 4 (2013)
Publisher : Faculty of Medicine Universitas Mataram

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Background: Hospital is a health facility that serve as a place of healing and restoration of health. The success rate of a hospital is usually evaluated in term of the utilization of facilities, quality and level of service efficiency. Since Moslems Hospital of Siti Hajar Mataram is one of the oldest private hospital in the city of Mataram and it had a great patient’s volume, the researchers intend to follow through with doing research on the relationship between patients’s perception about health care quality in inpatient care and the image of Moslems Hospital of Siti Hajar Mataram. Methods: A cross-sectional study was performed using consecutive sampling. The participants recruited were patients admitted to inpatient care in the Moslems Hospital of Siti Hajar Mataram. Data were collected using questionnaire. A pilot test was done to evaluate validity and reliability of the questionnaire prior to data collection. Data were analysed with descriptive analysis; bivariate analysis using spearman method; and multivariate analysis using multiple linear regression to determine the effect on the health care quality toward hospital’s image. Results: Multivariate analysis showed that the variable quality of medical services, supporting examinations, nurses, administration and management significantly affected the image. Administrative and management service was the most dominant variable. Based on the results of the ANOVA test, p-value obtained was 0,000. Adjusted R2 value obtained was 0.634, indicating that the equations was good discrimination. Conclusion: There is a relationship between the quality of medical services, supporting examination, nurses, administration and management with the image of Moslems Hospital of Siti Hajar Mataram. Keywords: Patient perception, Inpatient care, Health Care Quality, Image of Hospital.
PENGARUH PEMBERIAN OPLOSAN MONOSODIUM GLUTAMATE (MSG) DAN ETANOL 10% DOSIS BERTINGKAT TERHADAP GRADASI KERUSAKAN OTAK TIKUS WISTAR Laily, Novita Shalatiah; Djannah, Fathul; Syamsun, Arfi
Jurnal Kedokteran Vol 3 No 1 (2014)
Publisher : Faculty of Medicine Universitas Mataram

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Latar belakang: Penyalahgunaan minuman beralkohol semakin meningkat, salah satunya minuman keras campuran (oplosan). Dalam pembuatan oplosan, alkohol jenis etanol sering dicampur dengan berbagai bahan, salah satunya dengan MSG (monosodium glutamate). Etanol dan MSG dalam jumlah berlebih bisa menimbulkan efek toksik yang merusak organ. Otak adalah organ paling vital dan sensitif, sehingga jika otak terkena efek toksik, akan mengganggu homeostasis tubuh. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian oplosan MSG dan etanol 10% dosis bertingkat terhadap gradasi kerusakan otak tikus wistar. Metode: Penelitian menggunakan desain penelitian eksperimental dengan rancangan Post Test Only Kontrol Group Design. Penelitian ini menggunakan 6 kelompok yaitu 3 kelompok kontrol dan 3 kelompok perlakuan. Kelompok kontrol negatif (KN) yaitu tikus yang mendapat aquadest 4 ml, kelompok kontrol 1 (K1) menggunakan etanol murni kadar 10% sebanyak 4 ml dan kelompok kontrol 2 (K2) menggunakan MSG yang diambil dari larutan dosis letal 16,6 gr/kgBB sebanyak 4 ml. Serta tiga kelompok perlakuan yaitu kelompok perlakuan 1 (P1) yang diberikan oplosan MSG dan etanol 10% dengan perbandingan 1:3 sebanyak 4 ml, kelompok perlakuan 2 (P2) yang diberi oplosan MSG dan etanol 10% dengan perbandingan 1:4 sebanyak 4 ml, kelompok perlakuan 3 (P3) yang diberi oplosan MSG dan etanol 10% dengan perbandingan 1:5 sebanyak 4 ml. Hasil: Terdapat perbedaan kerusakan otak yang bermakna antara kelompok KN dengan P3 (p=0,019) dan kelompok P1 dengan P3 (p=0,019), juga antara kelompok P2 dengan P3 (p=0,019) dengan p
HUBUNGAN ANTARA PERSEPSI PASIEN RAWAT INAP TENTANG KUALITAS PELAYANAN KESEHATAN DENGAN CITRA RUMAH SAKIT UMUM PROVINSI NUSA TENGGARA BARAT Sakti, Pandu Tridana; Syamsun, Arfi; Ekawanti, Ardiana
Jurnal Kedokteran Vol 3 No 1 (2014)
Publisher : Faculty of Medicine Universitas Mataram

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Background: The hospital is a central care facility that is important as a central referral point for the lower care centers. Therefore, the hospital is required to provide adequate facilities and infrastructures, good quality and equity for all patients. The 2011 annual report of Provincial General Hospital West Nusa Tenggara indicated that the quality of health services in this hospital was low. It was felt necessary to undergo a research study to find out the inpatients perception of health care. Methods: A cross-sectional study was performed using stratified random sampling. The participants chosen were all inpatients of the Provincial General Hospital West Nusa Tenggara. A sample of inpatients was thus obtained of which questionnaires were usable for data analysis. A validity and reliability tested self administered questionnaire was used. Data was analysed with descriptive analysis, bivariate analysis using spearman method, and multivariate analysis using multiple linear regression to determine the effect on the health care quality toward hospital’s image. Results: Multivariate analysis showed that variables of health care quality (medical service, nurses, administration, supporting examination, pharmaceutical, nutritional, and physical facilities) significantly effected the image of the hospital. Based on the results of anova test, p value obtained was 0.000. Adjusted R2 value obtained was 0.966, indicating that the equation was good discrimination. Conclusion: There is a relationship between the quality of medical service, nursing, administration, supporting examination, pharmaceutical, nutritional, and physical facilities and the image of the Hospital. Keywords: Perception, Inpatients, Health Care Quality, Image, Hospital.
HUBUNGAN ANTARA PERSEPSI PASIEN TERHADAP KUALITAS PELAYANAN KESEHATAN DENGAN CITRA PUSKESMAS DI KOTA MATARAM Prahasti, I Dewa Ayu Yulisa; Ekawanti, Ardiana; Syamsun, Arfi
Jurnal Kedokteran Vol 3 No 1 (2014)
Publisher : Faculty of Medicine Universitas Mataram

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Latar belakang: Puskesmas merupakan akses pelayanan kesehatan pertama serta dibangun untuk menyelenggarakan pelayanan dasar, menyeluruh dan terpadu. Oleh karena itu, perlu dilakukan peningkatan mutu, pemerataan dan keterjangkauan pelayanan kesehatan puskesmas bagi seluruh masyarakat. Peningkatan mutu pelayanan kesehatan puskesmas melalui upaya kesehatan wajib dan upaya kesehatan pengembangan akan mempengaruhi persepsi pasien terhadap citra Puskesmas di Kota Mataram. Berdasarkan laporan kunjungan pasien puskesmas tahun 2011 di Kota Mataram terdapat penurunan jumlah kunjungan pasien di Puskesmas Karang Taliwang. Berdasarkan data tersebut, perlu dilakukan penelitian untuk mengetahui hubungan antara persepsi pasien terhadap kualitas pelayanan puskesmas di Kota Mataram. Metode: Rancangan penelitian ini adalah cross sectional. Teknik pengambilan sampel yang digunakan adalah consecutive sampling. Sampel yang digunakan adalah semua pasien yang berobat ke 8 Puskesmas di Kota Mataram. Pengambilan data dilakukan dengan menggunakan instrumen penelitian berupa kuesioner yang telah diuji validitas dan reliabilitas. Analisis statistik yang digunakan adalah analisis deskriptif, analisis bivariat menggunakan metode uji spearman, dan analisis multivariat menggunakan uji regresi liniear berganda untuk mengetahui pe ngaruh kualitas pelayanan kesehatan terhadap citra Puskemas. Hasil: Hasil analisis multivariat menunjukkan bahwa variabel kualitas pelayanan yang paling berpengaruh terhadap citra Puskesmas di Kota Mataram adalah variabel pelayanan sarana dan prasarana, tenaga kesehatan dan pelayanan administrasi. Berdasarkan hasil uji ANOVA, nilai p yang didapatkan adalah 0,000. Nilai Adjusted R2 yang didapatkan adalah 0,683, hal ini menunjukan bahwa persamaan yang didapatkan mempunyai diskriminasi yang baik. Kesimpulan: Terdapat hubungan antara kualitas pelayanan sarana dan prasarana puskesmas, tenaga kesehatan, tenaga non kesehatan, pelayanan adminitrasi, jaminan pelayanan puskesmas terhadap citra Puskesmas di Kota Mataram. Kata kunci: Persepsi Pasien, Kualitas Pelayanan Kesehatan, Citra Puskesmas.
PENGARUH PEMBERIAN OPLOSAN MSG DAN ETANOL 10% DOSIS BERTINGKAT TERHADAP GRADASI KERUSAKAN JANTUNG TIKUS WISTAR Paparan MSG dan Tuak Fermentasi Dosis Bertingkat terhadap Gradasi Kerusakan Jantung Tikus Wistar Nirmalasari, Nur Oktia; Djannah, Fathul; Syamsun, Arfi
Jurnal Kedokteran Vol 3 No 1 (2014)
Publisher : Faculty of Medicine Universitas Mataram

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Pendahuluan: Penyalahgunaan minuman beralkohol di dunia terus meningkat. Di Indonesia, telah ditemukankasus kematian akibat konsumsi oplosan minuman beralkohol dengan berbagai bahan, salah satunya monosodium glutamat (MSG). Alkohol dengan komponen utama etanol berbahaya bagi tubuh, terutama jantung. Sementara itu penggunaan MSG dalam makanan masih diragukan. Etanol dan MSG adalah bahan yang jika berlebihan dalam tubuh dapat menimbulkan gangguan berbagai organ. Tujuan penelitian ini adalah mengetahui pengaruh pemberian oplosan MSG dan etanol 10% dosis bertingkat terhadap gradasi kerusakan jantung pada hewan percobaan tikus Wistar. Metodologi peneliian: Penelitian menggunakan desain penelitian eksperimental sederhana dengan rancangan post-test only control group design. Penelitian ini menggunakan 6 kelompok yaitu 3 kelompok kontrol dan 3 kelompok perlakuan. Pada kelompok kontrol negatif (KN) diberikan aquades, kelompok kontrol pertama (K1) diberi etanol, kelompok kontrol kedua (K2) diberi larutan MSG dosis letal 16,6 g/KgBB. Sementara kelompok perlakuan 1 (P1) diberi campuran MSG dan etanol dengan perbandingan 1:3, perlakuan 2 (P2) diberi campuran MSG dan etanol dengan perbandingan 1:4, perlakuan 3 (P3) diberi campuran MSG dan etanol dengan perbandingan 1:5. Seluruh kelompok diberikan perlakuan sebanyak 4 ml, selama 7 hari dengan jarak 2 hari. Setelah 14 hari, tikus dibius, diambil organ jantung melalui pembedahan, dan difiksasi dengan formalin 10% untuk pemeriksaan mikroskopis. Hasil: Terdapat perbedaan gambaran histopatologi jantung yang bermakna antara KN dengan P3 (p=0,005), P1 dengan P3 (p=0,005), P2 dengan P3 (p=0,005) dimana p
ANALISIS KADAR TIMBAL DALAM RAMBUT AKIBAT PAPARAN KRONIS PADA SOPIR KENDARAAN UMUM DI KOTA MATARAM Hidayati, Nurul; Syamsun, Arfi; Cenderadewi, Muthia
Jurnal Kedokteran Vol 3 No 1 (2014)
Publisher : Faculty of Medicine Universitas Mataram

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Latar Belakang dan Tujuan: Pencemaran logam berat, salah satunya timbal, dapat menimbulkan bahaya bagi makhluk hidup. Timbal dapat terakumulasi di dalam organ atau jaringan tubuh seperti otak, hati, ginjal, limpa, kuku, rambut, tulang, dan lain – lain dan merusak jaringan tersebut. Sopir merupakan salah satu kelompok yang berisiko tinggi terpapar oleh polusi timbal.Tujuan penelitian ini adalah untuk mengetahui apakah terdapat timbal di dalam rambut sopir kendaraan umum di Kota Mataram dan berapakah kadar timbal dalam rambut sopir kendaraan umum di Kota Mataram tersebut. Metode: Penelitian menggunakan desain penelitian deskriptif analitik dengan cara potong lintang, melibatkan 60 orang sampel yang berprofesi sebagai sopir kendaraan umum yang telah bekerja sebagai sopir selama minimal 2 tahun. Hasil: Terdapat kadar timbal dalam rambut akibat paparan kronis pada sopir kendaraan umum di Kota Mataram dengan kadar rata – rata adalah 8,4085 μg/g dengan persentase 28,3% di atas normal dan 71,7% dalam batas normal. Simpulan: Terdapat kadar timbal dalam rambut akibat paparan kronis pada sopir kendaraan umum di Kota Mataram dengan kadar rata – rata 8,4085 μg/g dengan persentase 28,3% di atas normal dan 71,7% dalam batas normal. Kata Kunci: Timbal, paparan kronis, sopir
PENGARUH PEMBERIAN OPLOSAN MONOSODIUM GLUTAMATE (MSG) DAN ETANOL 10% DOSIS BERTINGKAT TERHADAP GRADASI KERUSAKAN HEPAR TIKUS WISTAR Pengaruh Paparan Dosis MSG dan Tuak Fermentasi Dosis Bertingkat terhadap Gradasi Kerusakan Hepar Tikus Wistar. Hidayati, Nurul; Syamsun, Arfi; Djannah, Fathul
Jurnal Kedokteran Vol 3 No 1 (2014)
Publisher : Faculty of Medicine Universitas Mataram

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Latar belakang: Penyalahgunaan minuman beralkohol dewasa ini semakin meningkat, salah satunya dengan cara dicampur (dioplos) dengan bahan lain. Bahan lain yang sering ditambahkan pada minuman keras beralkohol salah satunya adalah monosodium glutamate (MSG). Organ hepar merupakan tempat utama metabolisme zat-zat yang masuk ke dalam tubuh sehingga kemungkinan terjadinya kerusakan jaringan pada organ ini sangat besar.Penelitian ini bertujuan untuk mengetahui pengaruh pemberian oplosan MSG dan etanol 10% dosis bertingkat terhadap gradasi kerusakan hepar tikus wistar. Metode: Penelitian menggunakan desain penelitian eksperimental dengan rancangan roandomized control group only design. Hasil: Menunjukkan adanya perbedaan yang bermakna antara kelompok kontrol negatif dengan kontrol satu (p=0,001), kelompok kontrol negatif dengan kelompok perlakuan dua (p=0,001) dan kelompok kontrol negatif dengan perlakuan tiga (p=0,001) dimana p
Co-Authors Adinda Citra Anisa Ansyori, Maz Isa Ardiana Ekawanti Arif Setyo Astuti, Anies Dyaning Atmawati, Baiq Jatna Auliya, Rosmeiti Emma Ayu Santia Dewi Bagas Ekasangga Baiq Wanda Annisa Candra Eka Puspitasari Dwi Astuti Wulandari Eka Arie Yuliyani Emira Alifia Eustachius Hagni Wardoyo Fathul Djannah Hakim, Faradila Khoirun Nisa Hamsu Kadriyan Harahap, Ida Lestari Harahap, Ida Lestari Herlina, Lenny I Dewa Ayu Yulisa Prahasti, I Dewa Ayu Yulisa I Komang Gerudug, I Komang I Made Arya Yogiswara Mahayasa Ida Ayu Kirtiasih, Ida Ayu Ida Lestari Harahap Ida Lestari Harahap Ida Lestari Harahap Ida Lestari Harahap Ida Lestari Harahap Ima Arum Lestarini Indana Eva Ajmala Januarman, Januarman Januarman, Januarman Januarman, Januarman Januarman, Januarman Januarman, Januarman Januarman, Januarman Jumsa, Muhammad Rizkinov Jurnal Pepadu Laily, Novita Shalatiah Leni Herlina Lenny Herlina Lenny Herlina Lina Nurbaiti, Lina Luthfiyah Kamila Muhammad Faeyza Muharrom, Siti Nurul Muthia Cenderadewi, Muthia Ni Made Amelia Ratnata Dewi Nisa, Hayatin Nur Oktia Nirmalasari, Nur Oktia Nurhidayati Nurhidayati Nurul Hidayati Oci Qonita Londo Woro Pandu Tridana Sakti, Pandu Tridana Prima Belia Fathana, Prima Belia Puji Arrohman, Puji Pujiarohman Pujiarohman Pujiarohman Pujiarohman Pujiarohman Pujiarohman Pujiarrohman Pujiarrohman Pujiarrohman Puspasari Mahadewi Putri, Sandra Yuliana Andini Putri, Yolanda Satriani PW, Ni Putu Ayu Dewanthi Rahayuningrum, Nurekayani Rendraswara, Wanda Rika Hastuti Setyorini Rina Lestari Rohadi Rohmayana, Sri Royani Widiyastuti Sari, Surya Meka Novita Shania Hafista Syari, Mayuarsih Kartika Triani, Eva Triani, Eva Ulfa Ramdhani Vini Fardila, Vini Wahyu Sulistya Affarah, Wahyu Sulistya Yusuf Alfian Yuvita Dewi Priyatni, Yuvita Dewi