Arina Dery Puspitasari
Department of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia

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A Community's Knowledge and Attitude in Recognizing Symptoms and Diarrhea Management in Children Arina Dery Puspitasari; Novitri Wulandari; Bindaria Mutmaina Prabawati; Liza Yudistira Yusan
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 9 No. 2 (2022): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v9i22022.101-106

Abstract

Background: Diarrhea is the world's second-biggest cause of death among children. Children suffer from severe dehydration due to the lack of understanding of treating diarrhea properly. Objective: This study aimed to assess the level of community knowledge and attitudes toward the treatment of diarrhea in children. Methods: This was an observational, cross-sectional study conducted in a community in Gresik, Indonesia, in 2019. A Likert scale questionnaire, consisting of 10 items on knowledge and five on community attitudes on diarrhea management in children, was used to collect data. Results: One hundred and seven participants responded to the survey, and 89.72% were women. 'Respondents' mean age was 41.84 ± 11.27 years with various levels of education. It was found that the community had good knowledge of diarrhea management in children, as shown by the finding that 84.11% of the participants provided the correct answers. About 87.85% of the participants were aware of the signs and symptoms of diarrhea in children. However, there is still a shortage of understanding about managing diarrhea properly, particularly when identifying the necessary medicine. About 89.72% of the participants demonstrated a "positive" attitude in diarrhea management, while approximately 78.51% agreed that children with diarrhea should be given oral rehydration. Conclusion: The knowledge about recognizing signs and symptoms of diarrhea in children was good, while the knowledge about diarrhea management needed to be improved. Overall, the respondents had a positive attitude about diarrhea management in children.
Isoprinosine along with Favipiravir or Oseltamivir in Patients with Moderate Covid-19 at RSD Dr. Soebandi Jember Chrysnanda Maryska; Didik Hasmono; Sofiati Diah Baisuni; Ayunda Nur Hidayatiningsih; Arina Dery Puspitasari; Retna Dwi Puspitarini; Budi Suprapti
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 9 No. 3 (2022): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v9i32022.209-219

Abstract

Background: Isoprinosine is an immunomodulator that is now being used to treat Covid-19 patients. Objectives: To evaluate Isoprinosine with Favipiravir or Oseltamivir in moderate Covid-19. Methods: In a retrospective observational analysis, in-hospital moderate Covid-19 patients treated between June 2020 and June 2021 were included. Results: Inclusion criteria for 364 patients were met, with 135 receiving Favipiravir-Isoprinosine (Group 1) and 229 receiving Oseltamivir-Isoprinosine (Group 2). In group 1, the majority of patients (58.50%) were female (35.60%), had no comorbidities (71.60%), were discharged with a positive PCR (74.80%), did not require a breathing apparatus (99.26%), had leukocyte levels between 4,5-11,0 (82.22%), lymphocyte levels between 25-33 (34.07%), and were discharged with no ground-glass opacity (34.07%) (54.10%), LOS was 9-13 days (50.37%), while the mortality rate was 0.70%. In group 2, the majority of patients were male (54.10%), with the highest age range being 42-56 years (35.80%), without comorbidities (69.0%), discharged with a positive PCR (72.50 %), and without the need for a breathing apparatus (99.13%), with leukocyte levels ranging from 4.5 – 11.0 (81.22 %), with lymphocyte levels ranging from 25.0 – 33.0 (26.20 %), and were discharged with no ground-glass opacity (49.34 %), LOS was 9 - 13 days (34.06 %), and the mortality rate was 0.87%.Conclusion: In this trial, it was determined that combining isoprinosine with antivirals favipiravir or Oseltamivir could produce significant clinical improvement.