Claim Missing Document
Check
Articles

Found 21 Documents
Search

Hubungan antara Periodontitis, Aterosklerosis dan Stroke Iskemik Akut Wijayanti, Punik Mumpuni; Setyopranoto, Ismail
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 8, No 2 (2008)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v8i2.1481

Abstract

During the last two decades, there has been an increasing interest in the impact of oral health on atherosclerosis and subsequent cerebrovascular disease. Cerebrovascular diseases or stroke are among the most prevalent causes of death and disablement in industrialized countries. The expression stroke summarizes sudden central nervous deficits of different but always vascular etiologies. Periodontitis has been related to stroke, butfindings have been inconsistent. Chronic infectious diseases, including periodontal disease, were linked to stroke risk. Gingivitis and periodontitis are among the most common human infections. Gingivitis can develop within days and includes inflammatory changes of the gingiva most commonly induced by accumulation of dental plaque.Periodontitis results from a complex interplay between chronic bacterial infection and the inflammatory host response, leading to irreversible destruction of tooth-supporting tissues, with tooth loss as a common end point. Periodontitis is associated with elevated markers of inflammation that are themselves indicators of stroke risk. Bacteria from periodontal pockets can enter the bloodstream during activities such as chewing or tooth brushing, and periodontal pathogens were identified in carotid plaques, but their role in atherogenesis is not yet understood. Selama dua dekade ini, terjadi peningkatan perhatian yang luar biasa terhadap penelitian tentang pengaruh kesehatan mulut dan aterosklerosis yang selanjutnya menyebabkan penyakit serebrovaskuler. Salah satu penyakit tersebut adalah periodontitis yang diduga berhubungan dengan stroke, walaupun demikian beberapa penelitian masih belum ada yang konsisten tentang hubungan tersebut. Penyakit infeksi kronik, termasuk penyakit jaringan periodontal, sudah ada beberapa penelitian yang membuktikan berhubungan dengan faktor risiko stroke. Gingivitis dan periodontitis masih merupakan penyakit infeksi rongga mulut yang sering dijumpai di masyarakat. Gingivitis dapat berkembang dalam beberapa hari dan selanjutnya menyebabkan perubahan inflamasi gingiva dan kemudian terjadi akumulasi plak gigi.Periodontitis merupakan hasil dari mekanisme yang komplek antara infeksi bakteri kronik dan respon inflamasi dari host, dan selanjutnya menyebabkan destruksi yang ireversibel pada jaringan pendukung gigi, dan akhirnya akan menyebabkan kehilangan gigi. Periodontitis sering didapatkan adanya peningkatan petanda-petanda inflamasi, dan hal tersebut juga merupakan infikator dari faktorrisiko stroke itu sendiri. Bakteri yang berasal dari pocket periodontal dapat masuk ke dalam aliran darah selama teijadi aktivitas rongga mulut misalnya pada waktu mengunyah atau gosok gigi, dan bakteri-bakteri periodontal yang patogen dapat diidentifikasi pada plak karotis, tetapi pengaruhnya terhadap proses pembentukan plak aterom (atherogenesis) belum dapat diketahui.
STROKE ISKEMIK DENGAN MANIFESTASI DIZZINESSVERTIGO TERISOLASI Diyan Anita Sari,* Sri Sutarni,* Ismail Setyopranoto*
NEURONA Vol. 37 No. 2 Maret 2020
Publisher : Neurona Majalah Kedokteran Neuro Sains

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

UNSTABLE WALKING OR LOSS OF BALANCE ARE SYMPTOMS IN ABOUT 50 OF STROKE CASES HOWEVER ONLY ABOUT 20 ARE ACCOMPANIED BY FOCAL NEUROLOGICAL SIGNS IN THE LAST DECADE THERE IS INCREASING EVIDENCE THAT VERTIGO CAN BE THE ONLY ISCHEMIC SYMPTOM OF POSTERIOR CIRCULATION STROKE WITHOUT A FOCAL SIGN THE PURPOSE OF THIS SYSTEMATIC REVIEW IS TO EXAMINE THE LITERATURE ON ISCHEMIC STROKE WITH THE MANIFESTATION OF ISOLATED DIZZINESSVERTIGO
PENGARUH POLA MAKAN TERHADAP KEJADIAN STROKE HEMORAGIK DI RUANG POLIKLINIK SARAF RSUD TGK CHIK DITIRO SIGLI Teuku Jauhardin,* Rachmat Andi Hartanto,* Endro Basuki,* Ismail Setyopranoto**
NEURONA Vol. 38 No. 1 Desember 2020
Publisher : Neurona Majalah Kedokteran Neuro Sains

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

INTRODUCTION INTRACEREBRAL HEMORRHAGE ACCOUNTS FOR 10 OF ALL STROKES AND IS ASSOCIATED WITH HIGH MORTALITY ACEH PROVINCE HAS A PREVALENCE OF STROKE AS MUCH AS 66 PER MILE THE DIET PATTERN OF ACEHNESE PEOPLE TENDS TO BE HIGH IN FAT AND PROTEIN BUT LOW IN FIBER CAUSES AN IMBALANCE IN NUTRIENT INTAKE A RISK FACTOR FOR HEMORRHAGIC STROKE
Hubungan antara Periodontitis, Aterosklerosis dan Stroke Iskemik Akut Wijayanti, Punik Mumpuni; Setyopranoto, Ismail
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 8, No 2 (2008)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v8i2.1481

Abstract

During the last two decades, there has been an increasing interest in the impact of oral health on atherosclerosis and subsequent cerebrovascular disease. Cerebrovascular diseases or stroke are among the most prevalent causes of death and disablement in industrialized countries. The expression stroke summarizes sudden central nervous deficits of different but always vascular etiologies. Periodontitis has been related to stroke, butfindings have been inconsistent. Chronic infectious diseases, including periodontal disease, were linked to stroke risk. Gingivitis and periodontitis are among the most common human infections. Gingivitis can develop within days and includes inflammatory changes of the gingiva most commonly induced by accumulation of dental plaque.Periodontitis results from a complex interplay between chronic bacterial infection and the inflammatory host response, leading to irreversible destruction of tooth-supporting tissues, with tooth loss as a common end point. Periodontitis is associated with elevated markers of inflammation that are themselves indicators of stroke risk. Bacteria from periodontal pockets can enter the bloodstream during activities such as chewing or tooth brushing, and periodontal pathogens were identified in carotid plaques, but their role in atherogenesis is not yet understood. Selama dua dekade ini, terjadi peningkatan perhatian yang luar biasa terhadap penelitian tentang pengaruh kesehatan mulut dan aterosklerosis yang selanjutnya menyebabkan penyakit serebrovaskuler. Salah satu penyakit tersebut adalah periodontitis yang diduga berhubungan dengan stroke, walaupun demikian beberapa penelitian masih belum ada yang konsisten tentang hubungan tersebut. Penyakit infeksi kronik, termasuk penyakit jaringan periodontal, sudah ada beberapa penelitian yang membuktikan berhubungan dengan faktor risiko stroke. Gingivitis dan periodontitis masih merupakan penyakit infeksi rongga mulut yang sering dijumpai di masyarakat. Gingivitis dapat berkembang dalam beberapa hari dan selanjutnya menyebabkan perubahan inflamasi gingiva dan kemudian terjadi akumulasi plak gigi.Periodontitis merupakan hasil dari mekanisme yang komplek antara infeksi bakteri kronik dan respon inflamasi dari host, dan selanjutnya menyebabkan destruksi yang ireversibel pada jaringan pendukung gigi, dan akhirnya akan menyebabkan kehilangan gigi. Periodontitis sering didapatkan adanya peningkatan petanda-petanda inflamasi, dan hal tersebut juga merupakan infikator dari faktorrisiko stroke itu sendiri. Bakteri yang berasal dari pocket periodontal dapat masuk ke dalam aliran darah selama teijadi aktivitas rongga mulut misalnya pada waktu mengunyah atau gosok gigi, dan bakteri-bakteri periodontal yang patogen dapat diidentifikasi pada plak karotis, tetapi pengaruhnya terhadap proses pembentukan plak aterom (atherogenesis) belum dapat diketahui.
Validity and reliability testing of home care stroke quality indicators Nur Chayati; Christantie Effendy; Ismail Setyopranoto
International Journal of Public Health Science (IJPHS) Vol 10, No 4: December 2021
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v10i4.20846

Abstract

It is disconcerting that until today there are no agencies or research to recommend the appropriate indicators of home nursing care of stroke patients according to Indonesian conditions. Hence, this research aimed to verify the validity and reliability of quality indicators of home nursing care for stroke patient that resulted from Delphy process. Confirmatory factor analysis was carried out for validity and reliability testing with data collected from 350 respondents. Based on the value of loading factors, 62 indicators were declared valid and five indicators were invalid. This study successfully proved the validity of 62 indicators of quality home care for stroke patients. Further research is needed to pilot project this indicator in a larger area.
Evaluasi Implementasi Program Jaminan Kesehatan Nasional terhadap Pasien Stroke di RSUP Dr. Sardjito Muhammad Dahlan; Ismail Setyopranoto; Laksono Trisnantoro
Jurnal Kebijakan Kesehatan Indonesia Vol 6, No 2 (2017)
Publisher : Center for Health Policy and Management

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (128.182 KB) | DOI: 10.22146/jkki.v6i2.28934

Abstract

ABSTRACTBackground: Since 2014, Indonesia has implemented universal health coverage. In Indonesia, it was named as Jaminan Kesehatan Nasional or JKN. “Quality control and cost control” is the tagline of these program. Health provider such as doctors, nurses and the others health provider must control the quality and the cost of the patient’s treatment. Stroke, as one of the disease which needed such a complex treatment, must be treated as effective as possible.Aim: The aim of this study is evaluating the implementation of the JKN in stroke care especially in Central hospital. Measuring the quality of the care in stroke unit is compulsory in implementation research. Knowing acceptability and fidelity of the rules from JKN by the doctors must be described.Method: This study is mixed method with sequential explanatory design. The qualitative research was a cross sectional research which began in June 15th-July 31st. Interview from three doctors in stroke unit Sardjito General Hospital were performed to know the acceptability of the program.Result: The quality of care in Unit Stroke RSUP Dr. Sardjito from the doctors are good. Rationalization of the drugs and safety of the patients were prioritized. From that conditions the unit got a debt condition. The financial performance from one patient could get debt up to eleven million rupiahs. From the qualitative research, the acceptability of the national formulation slightly didn’t accept by the doctors. Neuro protector and another kind of drugs isn’t on the list. rtPA which can be found in the list is too expensive. Reimbursement from the BPJS was too low. Homecare as one the rehabilitation isn’t covered by BPJS. Back referral system to general practitioner isn’t accepted by the neurologist because of the lack of the facility in puskesmas or PPK I. Research and education in academic hospital didn’t do well because of the lack of patients.Conclusion: National formularies are needed to revised based on the patients need. Reimbursement from BPJS should be higher than before. Homecare patients should be guaranteed by BPJS. Keywords: Universal health coverage, stroke, quality care, implementation research ABSTRAKLatar Belakang: Era baru program asuransi kesehatan nasional mulai 1 Januari 2014 yang diselenggarakan oleh BPJS Kesehatan yang mempunyai target bahwa seluruh masyarakat telah menjadi peserta BPJS pada tahun 2019. Apresiasi diberikan kepada pemerintah atas usahanya melaksanakan JKN. Dalam pelaksanaannya, evaluasi perlu dilakukan terhadap program ini. Stroke sebagai salah satu penyakit mematikan dan perlu manajemen yang menyeluruh patut untuk dievaluasi. Penerimaan penyedia pelayanan kesehatan dalam hal ini dokter perlu diidentifikasi.Tujuan: 1) Mengukur kinerja pelayanan; 2) Mengukur kinerja keuangan; 3) mengetahui penerimaan dan ketaatan pemberi pelayanan terhadap aturanMetode: mixed method dengan desain sekuensial ekplanasi. Penelitian kualitatif merupakan cross sectional dimulai 15 Juni–31 Juli. Interview dengan tiga dokter di Unit Stroke Rumah Sakit Umum Pusat Sardjito dilakukan untuk menggambarkan penerimaan.Hasil: Mutu pelayanan penyakit stroke sudah sesuai dengan mutu standar. Rasionalisasi obat, maupun pemulangan pasien tetap sesuai standar. Performa keuangan dari Unit Stroke mengalami kerugian. Penerimaan dari para dokteer terkait beberapa aturan seperti sistem rujukan dan standar tarif belum diterima sepenuhnyaKesimpulan: Permasalahan program Jaminan Kesehatan Nasional masih terjadi. Perbedaan persepsi antara pembuat aturan dengan pemberi pelayanan masih menonjol. Performa keuangan dari unit stroke mengalami kerugian walaupun mutu pelayanan sudah dilakukan secara optimal. Sistem rujukan terutama rujuk balik belum dapat dirasa layak oleh para dokter karena keterbatasan di PPK I. Pelayanan home care yang biasa digunakan tidak dapat optimal karena peserta asuransi belum mendapatkan jaminan untuk memperoleh pelayanan home care. Kata Kunci: jaminan kesehatan nasional, stroke, quality care, implementation research
Development of motor learning implementation for ischemic stroke: finding expert consensus Umi Budi Rahayu; Samekto Wibowo; Ismail Setyopranoto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 49, No 4 (2017)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2769.082 KB) | DOI: 10.19106/JMedSci004904201706

Abstract

The main purpose of this study was to investigate motor learning implementation forischemic stroke from experts on the field of motor learning in stroke patients includingthe neurologist, medical rehabilitation specialists and physiotherapists. To collect thedata and answer the research questions, statements were made on the basis of thestudy of literature and the grains exploration of the statements in the questionnaire usingthe Delphi Method. Formulation development model was based iteration or judgmentof experts. Validation assessment statement grain tested by the Content Validity Ratio(CVR) and Content Validity Index (CVI) was used to analyze the data. The finding clearup that CVR value of each item statement was 1 and the value of CVI also 1. There were6 indicators in a 26-point declaration on the implementation of the development model ofmotor learning intervention for ischemic stroke. Six indicators included basic theories thatsupport the importance of intervention motor learning, motor learning stages, principlesof motor learning, dosage, timing of and kinds of motor learning interventions that can beprovided as well as application development intervention model motor learning, allowinggiven for ischemic stroke. In conclusion, based on the content validity of the results ofthe consensus expert judgments are six indicators of the importance of motor learningapplication for ischemic stroke.
Prognostic factors for mortality in patients with severe traumatic brain injury in Yogyakarta, Indonesia Desin Pambudi Sejahtera; Ismail Setyopranoto; Indarwati Setyaningsih; Sri Sutarni; Tri Ratnaningsih
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 52, No 2 (2020)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (309.986 KB) | DOI: 10.19106/JMedSci005202202003

Abstract

Determining an accurate prognosis in patients with severe traumatic brain injury (TBI) still becomes a difficult challenge for neurologists. Clinical and laboratory findings have been used as important parameters to establish clinical decisions or even predict future prognosis including death in these patients. We studied the clinical, laboratory and neuroimaging parameters in predicting mortality in patients with severe TBI. This study used the medical records of severe TBI cases in Dr. Sardjito General Hospital, Yogyakarta, Indonesia from January 2015 until July 2016. We evaluated the clinical, laboratory, and neuroimaging examinations of seventy patients with severe TBI in association with mortality. The result showed among 70 patients involved, 35 were dead. Clinical findings of age <40 y.o. (OR=1.143; p=0.015), multiple injuries (OR=5.712; p=0.045), and systolic blood pressure >140 mmHg (OR=3.852; p=0.008) were associated with mortality. Laboratory and neuroimaging parameters of hyponatremia (OR=3.667; p=0.027), hyperkalemia (OR=1.771; p=0.030), and the presence of traumatic subarachnoid hemorrhage (SAH) (OR=6.526; p=0.003) in head CT-scan were significantly associated with mortality. In conclusion, our study showed that productive age <40 y.o. multiple injuries, hyponatremia, hyperkalemia and the presence of traumatic SAH increase the mortality risk in patients with severe TBI.
Neurological findings in patients with COVID-19: a systematic review Mawaddah Ar Rochmah; Sekar Satiti; Ismail Setyopranoto; Indra Sari Kusuma Harahap; Desin Pambudi Sejahtera; Dhite Bayu Nugroho; Sri Sutarni
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 52, No 3 (2020): Special Issue: COVID-19
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (313.476 KB) | DOI: 10.19106/JMedSciSI005203202010

Abstract

Since the emerging of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in Wuhan, China at the end of 2019, the coronavirus disease 2019 (COVID-19) has become pandemic for months. Due to fast increased number of the positive patients with COVID-19, SARS-CoV-2 is considered highly pathogenic virus with various clinical presentations. Apart from the typical respiratory symptoms, neurological complains in COVID-19 involving central and peripheral nervous systems have been reported. This paper aimed to review the neurological findings reported in patients with COVID-19. We qualitatively reviewed studies reporting COVID-19 patient(s) with neurological manifestations according to the recommendations of PRISMA statement.There were twelve studies included in this brief review. We found that patients with neurological findings were reported ranging from symptomatic complain of headache and dizziness to specific neurological diseases/syndromes, such as meningitis/encephalitis, acute cerebrovascular diseases, Guillain-Barré syndrome, and Miller Fisher syndrome. This review suggests the possible neurological involvement in COVID-19. We hope to raise the awareness of the health workers in taking care of the patients with COVID-19 and neurological diseases.  
Analisis Mikrobia dan Organoleoptik Makanan Cair Instan Berbasis Pangan Lokal untuk Perbaikan Status Gizi Pasien Susetyowati Susetyowati; Lily Arsanti Lestari; Herni Astuti; Ismail Setyopranoto; Probosuseno Probosuseno
Amerta Nutrition Vol. 4 No. 3 (2020): AMERTA NUTRITION
Publisher : Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v4i3.2020.225-230

Abstract

ABSTRACT Background: Every hospital has high demand of nutritional support for patient but limitation of hospital funding to get commercial enteral nutrition that may influence the hospital of making its own enteral nutrition. It has some weakness such as not ready to use, not durable, and unstandardized nutrition content. Pumpkin, fish cork, and tempeh are less costly local food which contain high protein and antioxidant that may lead nutritional status improvement. Objectives: Determining total fungal count, total bacterial count and organoleptic properties of instant local food based-enteral nutrition.Methods: Pure-experimental study with completely random design was conducted on March-August 2018.  There are 4 flavors of the instant formula such as vanilla, ginger, cinnamon, and original. Total fungal count (TFC) and total bacterial count (TBC) were used for microbiological analysis. Organoleptic properties was evaluated by 80 panelists from Yayasan Stroke Indonesia. Inclusion criterias: aged 19-years or above and signing the informed consent. Organoleptic evaluation determined by 5 score of appearance, taste, texture, odour and overall formula. Statistical analysis used Kruskal Wallis to determine the difference of enteral nutrition acceptability for each flavor. Results: Mean of TBC of local food based-enteral nutrition was 3.5 x 104 ± 0.14 cfu/mg and mean of TFC was 1.65 x 102 ± 0.21 cfu/g. The acceptability of local food based-enteral nutrition was significantly different based on taste, odour, and overall aspect.Conclusions: Based on microbiology analysis showed that local food based-enteral nutrition was desirable. Panelist liked original flavor most based on appearance, taste, and texture. While the vanilla flavor was liked the most based on the odour and overall aspect. The score of acceptability showed significantly different on ginger, vanilla, and original flavors based on taste, odour, and overall aspect.ABSTRAKLatar Belakang: Tingginya kebutuhan dukungan gizi pasien namun terbatasnya biaya penyediaan makanan enteral komersial mendorong Rumah Sakit (RS) untuk membuat formula enteral sendiri. Kekurangan dari formula enteral buatan RS diantaranya tidak praktis, tidak tahan lama, dan nilai gizi yang tidak terpantau. Labu kuning, ikan gabus dan tempe merupakan bahan pangan lokal yang terjangkau dengan kandungan protein dan antioksidan tinggi  bermanfaat untuk perbaikan status gizi.Tujan: Mengetahui angka total mikrobia (bakteri dan jamur) dan sifat organoleptik dari makanan cair instan berbasis pangan lokal.Metode: Penelitian eksperimental dengan rancangan acak lengkap dilakukan pada Maret-Agustus 2018. Formula makanan cair memiliki 4 varian: vanilla, jahe, kayu manis, dan original. Analisis mikrobiologi menggunakan metode angka lempeng total (ALT) untuk bakteri dan jamur. Pengujian sifat organoleptik formula dilakukan oleh  80 panelis tidak terlatih dari anggota  Yayasan Stroke Indonesia. Kriteria inklusi untuk panelis uji organoleptik antara lain bersedia menjadi panelis dengan mengisi informed consent, usia ≥19 tahun. Uji organoleptik dengan 5 skala kesukaan berdasarkan aspek warna, aroma, rasa, tekstur, dan keseluruhan. Uji statistik menggunakan Kruskal Wallis untuk melihat perbedaan tingkat kesukaan dari tiap varian formula makanan cair.Hasil: Hasil analisis mikrobia dari formula menunjukkan rerata ALT bakteri 3,5 x 104 ± 0,14 cfu/mg, dan ALT jamur 1,65 x 102 ± 0,21 cfu/g. Terdapat perbedaan yang signifikan pada tingkat kesukaan varian formula makanan cair dari segi rasa, aroma, dan keseluruhan formula.Kesimpulan: Uji mikrobia formula makanan cair masih dalam batas aman untuk dikonsumsi. Responden paling menyukai varian rasa original dari aspek warna, rasa, dan tekstur, sedangkan secara keseluruhan dan aroma formula rasa vanilla yang paling disukai. Perbedaan rerata skor yang signifikan ditunjukkan pada varian rasa jahe, vanilla dan original dari segi rasa, serta varian rasa jahe dengan vanilla dari segi aroma dan keseluruhan.