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Menul Ayu Umborowati, Menul Ayu
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Immunology & microbiology Public Health

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Eosinophil and Eosinophil Cationic Protein Level Raising in Dermatitis Due to Food Patients Umborowati, Menul Ayu; Sawitri, Sawitri; Hoetomo, Marsoedi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 2 (2015): BIKKK AGUSTUS 2015
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (115.225 KB) | DOI: 10.20473/bikkk.V27.2.2015.90-96

Abstract

Background: Food allergy prevalence worldwide has been increase. Skin is secondary most often target organ in food allergy reaction. Food allergy affects 35% atopic dermatitis (AD) patients. Diagnosis of food allergy  is still challenge because signs are not specific. Previous researches showed eosinophil and eosinophil cationic protein (ECP) role in food allergy reaction on gastrointestinal tract, but none on dermatitis due to food. Purpose: To evaluate eosinophil and serum ECP in dermatitis due to food. Method: This is a descriptive observational cross sectional study, with dermatitis due to food patients in Dermatovenereology Outpatient Clinic Dr. Soetomo General Hospital Surabaya as subjects. Subjects has been collected trough consecutive sampling during 3 months, then data were analysized descriptively Results: Serum ECP level of dermatitis due to food patients were above normal range in all subjects, with mean level 108.5 µg/L, lowest level 33.011 µg/L and higher level 284.849 µg/L. Mean eosinophil of dermatitis due to food patients just arise above normal limit (0.413µg/L). AD patients were 48.4% among all subjects. Mean serum ECP level of AD patients was higher (121.703 µg/L) than non-AD (96.123 µg/L). Conclusions: Eosinophil and ECP seems have role in dermatitis due to food pathogenesis. Serum ECP examination can be benefits to monitor dermatitis due to food severity.Key words: dermatitis due to food, eosinophil, serum eosinophil cationic protein.
StudiRetrospektif:Diagnosis dan Terapi Pasien Melasma Umborowati, Menul Ayu; Rahmadewi, Rahmadewi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 1 (2014): BIKKK APRIL 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (388.071 KB) | DOI: 10.20473/bikkk.V26.1.2014.1-8

Abstract

Latar belakang:Melasmaadalah penyakit yang banyak dijumpai terutama dinegara beriklim tropis seperti Indonesia. Masalah yang dihadapi adalah responsterhadap terapiyang beragam, sehingga diagnosis dan terapi yang tepat untuk penyakit ini masih perlu terus dikembangkan.Tujuan: Mengevaluasi penegakan diagnosis dan pemberian terapi melasma guna meningkatkan pelayanan terhadap pasien di masa yang akan datang. Metode:Penelitian retrospektif pasienmelasma di Divisi Kosmetik Medik Unit Rawat Jalan (URJ) Kulit dan Kelamin RSUD Dr.Soetomo Surabaya selama periode 1 Januari 2009 sampai dengan 30Desember 2011. Data diperoleh dari rekam medis.Hasil:Pasienmelasma sebanyak 14,1% dari seluruh pasienbaru Divisi Kosmetik Medik, pasienperempuan sebanyak 99,2% dengan faktor pencetus utama adalah sinar matahari. Diagnosis ditegakkan dari pemeriksaan fisik dan lampu Wood, terapi topikal yang banyak diberikan adalah tabir surya, formula Kligman, dan Alpha Hydroxy Acid(AHA).Simpulan:Metode penegakan diagnosis dan pilihan agen pemutih sebagai terapi melasma di Divisi Kosmetik Medik URJ Kulit dan Kelamin RSUD Dr.Soetomo Surabaya masih perlu dievaluasi sesuai dengan bukti dan temuanterbaru.Kata kunci:melasma, studi retrospektif, diagnosis, terapi.
Co-Authors Marsoedi Hoetomo, Marsoedi Rahmadewi Rahmadewi Sawitri Sawitri