<![CDATA[The 21st century has shifted the direction of education in many countries to move forward with an interdisciplinary paradigm. As a consequence, it also induces alteration in the design of learning in the class. This research aims to (1) develop a biology learning module based on Science, Technology, Environment Art, Society and Language integration in the scope of biology learning; (2) examine the appropriateness of such developed-module; (3) reveal students’ response toward such module. This development effort is necessary to elaborate a trend of modern interdisciplinary learning by constructing collaboration between Biology, English, and the other sciences. The essential topics provided in this module comprise the scientific method, biodiversity, the relation among humans, nature, art, and technology, etc. This research employs the method of Research and Development (R&D) by the design of 4D: define, design, develop and disseminate. The skills of the 21st century trained in this learning encompass communication skills, cooperation, time management, creative-critical thinking skill, and problem-solving. The instruments of this research are a sheet of validation expert, observation sheet, and questionnaire. Sources of data consist of learning experts, language experts, media expert, content expert, and 50 students. Data analysis uses an analytical, descriptive technique. The result of research shows: (1) Learning module based on STEALS-integration is assessed as highly appropriate (average score of 93,25); (2) Students give positive responses to such developed module (average percentage of 87,75%). Thus, this module can comprehensively contribute to adding academic discourse on interdisciplinary learning and improvement of the 21st century’s skills for students. ]]>
