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All Journal Jurnal Riset Kefarmasian Indonesia Jurnal Ilmiah Pharmacy
Irene Puspa Dewi, Irene Puspa
Akademi Farmasi Prayoga
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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FORMULASI EKSTRAK KLOROFORM DAUN BELIMBING WULUH DALAM BENTUK SEDIAAN GEL dan UJI AKTIVITAS ANTIBAKTERI TERHADAP Staphylococcus epidermidis Tan, Verawaty; Rahmadhani, Nova Tri; Dewi, Irene Puspa
Jurnal Riset Kefarmasian Indonesia Vol 1 No 3 (2019): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (610.459 KB) | DOI: 10.33759/jrki.v1i3.54

Abstract

Herbal treatments are needed to treat various diseases, one of which is the leaves of Belimbing Wuluh (Averrhoa bilimbi L.). The aim of this study was to formulate chloroform extract of Belimbing Wuluh’s leaf (Averrhoa bilimbi L.) into gel preparations that were good, effective, and safe to use and to determine the antibacterial activity of chloroform extract of Belimbing Wuluh (Averrhoa bilimbi L.) leaf extract to Staphylococcus epidermidis by well method. The results showed that form of gel is a thick, dark green, the distinctive smell of Wuluh starfruit leaf extract, homogeneous, good skin pH, good washing and does not irritate the skin. This study uses Nutrient Agar media as a culture medium for Staphylococcus epidermidis bacteria. The results indicate that the chloroform extract gel leaves of belimbing wuluh leaves in formula 1 (10%), formula 2 (20%), and formula 3 (30%) were able to inhibit the growth of Staphylococcus epidermidis bacteria. In formula 3 (30%) gel extract of belimbing wuluh leaves has the widest zone of inhibition compared to other dosage formulas. The statistical test using the One Way ANOVA test showed a significant difference from the average diameter of the inhibition zone between all concentrations of chloroform extract gel leaves of belimbing wuluh leaves that were significant with (α ˂ 0.05).
EFEKTIVITAS GEL EKSTRAK ETANOL BAWANG PUTIH (Allium sativum L.) TERHADAP BAKTERI Staphylococcus aureus Dewi, Irene Puspa; Orde, Ilham Maslan; Verawaty, Verawaty
Jurnal Riset Kefarmasian Indonesia Vol 2 No 2 (2020): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v2i2.84

Abstract

Garlic (Allium sativum L.) is one of the traditional medicines which has an antibacterial efficacy compound namely Allisin which is able to inhibit the growth of Staphylococcus aureus bacteria. This study aims to formulate the garlic bulb extract into a good gel preparation for use as an acne drug and to determine the antibacterial effectiveness of the ethanol extract of garlic gel against the bacterium Staphylococcus aureus using the wells method. The gel evaluation was carried out to meet the requirements with organoleptic test parameters, homogeneity, pH, spreadability, adhesion and irritation test. This study uses extracts of 10% and 20% concentrations, at each concentration being able to inhibit the growth of Staphylococcus aureus bacteria. In the formula, the concentration of 20% has a inhibition zone diameter of 1.59 cm and a concentration of 10% has a inhibition of 1.50 cm. Statistical test results using the One Way ANOVA test found that there was no significant difference between the average diameter of inhibition of garlic extract gel concentration of 10% with a concentration of 20%.
AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAN EKSTRAK AIR BUNGA TASBIH (Canna hybrida Hort.) MENGGUNAKAN METODE DPPH (1,1-difenil-2 pikrihidrazil) Dewi, Irene Puspa
Jurnal Ilmiah Pharmacy Vol 6, No 2 (2019)
Publisher : Sekolah Tinggi Kesehatan Al-Fatah Bengkulu

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Abstract

Bunga tasbih (Canna hybrida Hort.) merupakan salah satu tanaman yang mengandung zat warna antosianin. Kandungan antosianin yang terdapat dalam buga berwarna merah dari tanaman tasbih berpotensi sebagai antioksidan alami. Penelitian ini bertujuan untuk mengetahui perbandingan antioksidan ekstrak etanol dan ekstrak air dari bunga tasbih (Canna hybrida Hort.). dalam penelitian ini dilakukan ekstraksi bunga tasbih dengan cara sokletasi untuk mendapatkan esktrak etanol dan infusa untuk mendapatkan ekstrak air. Masing-masing ekstrak di uji aktivitas antioksidan terhadap DPPH (1,1-Diphenyl-2-picrihydrazil) sebagai radikal bebas. Dilakukan uji antioksidan secara kuantitatif untuk memperoleh IC50 dari masing-masing ekstrak menggunakan spektrofotometer UV-Vis pada λmax 514 nm. Hasil pengukuran secara spektrofotometri menunjukkan bahwa ekstrak etanol bunga tasbih termasuk antioksidan sangat kuat karena memiliki nilai IC50 sebesar 26,50 ppm, sedangkan ekstrak air bunga tasbih termasuk antioksidan kuat karena memiliki nilai IC50 sebesar 63,02 ppm. Dalam penelitian ini digunakan vitamin C sebagai pembanding dan didapatkan IC50 sebesar 7,478 ppm. Ekstrak etanol dan ekstrak air bunga tasbih memiliki aktifitas antioksidan yang lebih kecil diandingkan vitamin C.
TINGKAT PEMAHAMAN TENAGA TEKNIS KEFARMASIAN TERHADAP OBAT PATEN DAN OBAT GENERIK DI KOTA PADANG Verawaty, Verawaty; Dewi, Irene Puspa; Kota, Fanny Millenia
Jurnal Riset Kefarmasian Indonesia Vol 4 No 1 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i1.230

Abstract

Patent drugs are drugs that still have patent rights and can only be produced by the manufacturer of the patent holder. while generic drugs are drugs whose patents have expired, so that they can be produced by all pharmaceutical companies. The purpose of this study was to determine the level of understanding of the pharmaceutical technical staff of Padang City on patent drugs and generic drugs. This research is a descriptive observational study using data collection instruments in the form of online questionnaires (google forms). The research variable is the respondent's level of understanding of generic and patent drugs. The respondents of this study were Pharmacy Technical Staff of Padang City, aged 20 years, both male and female, as many as 55 respondents. The sampling technique in this study was non-purposive sampling in accordance with the inclusion and exclusion criteria. Determination of the sample size in this study using the Slovin formula with an error rate of 5%. Collecting data by distributing online questionnaires via Google Forms. The data obtained is coded and entered into an Excel worksheet. The results showed that the level of understanding of the pharmaceutical technical staff of Padang City on patent drugs and generic drugs was categorized as sufficient (74.5%).
Co-Authors Kota, Fanny Millenia Luh Putu Ratna Sundari Orde, Ilham Maslan Rahmadhani, Nova Tri Tan, Verawaty