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Restu Megadiana Sukoco, Restu Megadiana
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Bioinformatic Analysis of Drug Candidate Compounds for Acquired Immunodeficiency Syndrome Sukoco, Restu Megadiana; Fauzi, Ahmad; Nuha, Ulin
Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015
Publisher : Proceeding International Conference on Global Resource Conservation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.209 KB)

Abstract

AIDS is a syndrome caused by HIV. The immune system of AIDS patient was too weak to fight off many infections. Many drugs developed to overcome these deadly disease. In this study, bioinformatic analysis performed on some drug candidate compounds that under development of FDA for AIDS’ patient. The drug candidate compounds are Amdoxovir, Alovudine, Elvucitabine, Dexelvucitabine, Capravirine, Darunavie, Calanolide-A, Tipranavir and Enfuvirtide. Molinspiration and preADMET web server has been used as tool for analyzing that drugs. As a results, our study revealed that not all of these drug candidate compounds fulfilled the Lipinski’s rule of five and toxicity test standart in silico.Keywords:Bioinformatic analysis; AIDS’ drug; Lipinski’s rule; toxicity test
The Inventory of Aquatic Macroinvertebrates in Various Waterfall in East Region of Malang, East Java Wijayanti, Erna; Fauzi, Ahmad; Widiansyah, Arindra Trisna; Mustofa, Zainul; Setyanto, Haqqi Anajili; Sukoco, Restu Megadiana; Nuha, Ulin; Fadilah, Rizka Elan
Proceeding International Conference on Global Resource Conservation Vol 6, No 1: Proceeding of 6th ICGRC 2015
Publisher : Proceeding International Conference on Global Resource Conservation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.209 KB)

Abstract

Indonesia as Maritime Island has many water regions. Waterfall is one of the water region that has a large number of aquatic macroinvertebrates. The aim of this research is to collect and identify the various aquatic macroinvertebrates that can be found in several waterfalls in east Region of Malang, East Java. The research was carried out on September until November 2015 in six waterfalls: Coban Jahe, Coban Pelangi, Coban Trisula, Coban Kembar, Coban Ringin Gantung and Coban Pitu. Dragnet was used to collect the samplesof aquatic macroinvertebrates in some sampling point. The result of this research was found 38 families that belonged to 18 ordo in 6 different classes: Insecta, Oligochaeta, Gastropoda, Hirudinae, Turbellaria, and Crustacea. The information about the inventory of aquatic macroinvertebrates will give another suggestion for the local government to conserve this animals especially waterfall environment, not only as tourist area but also as a source of knowledge to do another research. Keywords: Aquatic macroinvertebrates; inventory; Malang; waterfalls
Co-Authors Arindra Trisna Widiansyah, Arindra Trisna Erna Wijayanti Haqqi Anajili Setyanto, Haqqi Anajili I Gusti Bagus Wiksuana Rizka Elan Fadilah, Rizka Elan Ulin Nuha, Ulin Zainul Mustofa, Zainul