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All Journal MNJ (Malang Neurology Journal)
Catur Ari Setianto, Catur Ari
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Neuroscience

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CORRELATION OF C-REACTIVE PROTEIN LEVELS WITH CLINICAL OUTCOME INTRACEREBRAL HEMORRHAGE STROKE PATIENTS Setianto, Catur Ari; Purnomo, Hari; Marhaendraputro, Eko Arisetijono; Santoso, Widodo Mardi
Malang Neurology Journal Vol 1, No 1 (2015): January
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (578.31 KB) | DOI: 10.21776/ub.mnj.2015.001.01.5

Abstract

Background. Increased levels of markers of inflammatory factors after hemorrhage stroke was able to predict poor clinical outcome. Until now, the role of C Reactive Protein (CRP) in the local inflammatory response and clinical determinants output remains unclear.Objective. To investigate the correlation of CRP level with poor clinical outcome as measured by Barthel Index. Methods. This study was an observasional cohort porspective study performed on haemorrhage stroke patients in Saiful Anwar General Hospital in Februari 2014 until April 2014.Results. There was significant correlation (p=0,01, r=0,613) between CRP levels to poor clinical outcome measured by Barthel Index.Conclusion. C Reactive Protein levels could predict poor clinical outcome as measured by Barthel Index in intracerebral hemorrhage patients.
FACTORS AFFECTING PROGNOSIS OF TUBERCULOUS MENINGITIS IN SAIFUL ANWAR GENERAL HOSPITAL MALANG Munir, Badrul; Prayudi, Firman; Setianto, Catur Ari; ., Siswanto
Malang Neurology Journal Vol 6, No 1 (2020): January
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2020.006.01.1

Abstract

Background. The mortality rate of tuberculous meningitis (TBM) is approximately 20-41%. The prognosis is influenced by clinical and radiologic features, laboratory findings, and therapy. Objective. To report factors affecting the prognosis of TBM patients in Saiful Anwar Hospital.Methods. The study design was a retrospective cohort with consecutive sampling. Data were taken from medical records of 47 patients from 2016-2017. The prognostic value used modified rankin scale showing good (0-2) and poor prognosis (3-6). The impact of clinical, radiological, and laboratory factors were investigated by univariate analysis and multiple logistic regression. Results. In this study, good (n=21) and bad (n=26) prognosis were compared. Patients with good prognosis experienced more episodes of seizure than poor prognosis (17% vs 4%; p = 0.011). Focal neurologic deficits was more prevalent in poor prognosis (4% vs. 23%, p = 0.012). Meningeal enhancement was more common in poor prognosis (21% vs 42%; p= 0.038). From multivariate analysis, we found that seizure and focal neurological deficit are independent prognostic factors (p=0.023 dan p 0.033).Conclusion. Clinical factors influencing prognosis of TBM in Saiful Anwar Hospital are seizure and focal neurological deficit. Focal neurological deficit is a poor prognostic factor. However, seizure is a good prognostic factor.  Keywords: prognostic factors, tuberculous meningitis
Co-Authors Badrul Munir, Badrul Eko Arisetijono HARI PURNOMO Prayudi, Firman Siswanto . Widodo Mardi Santoso, Widodo Mardi