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Chronic Effect Various Type of Exercises to Fasting Blood Glucose and Insulin Resistance Machrina, Yetty; Purba, Ambrocious; Lindarto, Dharma; Daulay, Milahayati
Sumatera Medical Journal Vol. 2 No. 2 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Exercise is non-pharmacological management for Diabetes Mellitus (DM) type-2. Previous study found that both eerobic and interval training improved insulin resistance. The aim of this study was to analyze the chronic effect various type of exercises to fasting blood glucose (FBG) and insulin resistance in DM type-2 model rats. It was an experimental study, twenty male Wistar rats, age 8 weeks, weight 150-180 gram as the object. Rats were given high fed diet for 4 weeks then injected streptozocin dose 30 mg/kgBB in citrate buffer pH 4.5 i.p, and 45 mg/kgBB at the following week. Groups were divided into i.e moderate continous training (MCT), severe continous training (SCT), slow interval training (SIT), and fast interval training (FIT). All groups were treated with ran on the treadmill three times a week for 8 weeks. Fasting blood glucose and fasting insulin were checked before and after intervention. Insulin resistance was determined by calculating HOMA-IR. Data analized with paired t-test (p<0,05). The results shown that all group significantly decreased fasting blood glucose and insulin resistance (p <0,05) after eight weeks exercise except insulin resistance in MCT group. Fasting blood glucose and insulin resistence post-test was found lowest in SIT groups in this study. In conclucions chronic effect of aerobic continous and aerobic interval in various intensity can decrease fasting blood glucose and insulin resistance in DM type-2 rat model. Slow interval training was the best exercise model to decrease insulin resistance.

Description Of Bag Load With Antropometry Of Elementary School Students Krishna Moorthi, Priya Darshini; Machrina, Yetty; Laksmi, Lidya Imelda; Yaznil, Muhammad Rizki
Sumatera Medical Journal Vol. 3 No. 1 (2020): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v3i1.3336

Background. Low back pain is one of the most common health problem among school students. Carrying heavy backpack to school is one of the cause of low back pain. Objectives. To identify the bag load carried by the students and antropometry of the students. Method. This research is a descriptive observasional with cross sectional method. Data used is a primer data which is from 268 students by measuring their body weight, height, bag weight and also by interviewing them using interview guidelines. Results. The results obtained from 268 elememtary school students of Siti Hajar mostly have normal nutritional status. The average bag weight at level I (6.071%), level II (8.510%) and level III (10.812%) where the majority of bag loads compared to elementary school antropometry were included in the mild category 47.6% at level I, 74.7% at level II and 84.3% at level III eventhough there were some children in the heavy category. 88.8% of children carry their school bags using two shoulders, with a duration of time <30 minutes (61.7%). Respondents who experienced back pain (4.9%) and who did not experience back pain (95.1%). Conclusions. The weight of Siti Hajar Elementary School children bag against antropometry has not exceeded the recommended load limit. Key words. Bag load, antropometry, cross-sectional, interview

Improved basic life support skills and patient transportation at ambulance drivers in Medan Tuntung and Medan Sunggal area to improve patient safety Yetty Machrina; Siregar, Kamal Basri; Nuraiza Meutia; Gema Nazri Yanni; Yunita Sari Pane
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 2 (2019): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

The technique of providing basic and quick life support (BHD) and transportation to patients with cardiac and pulmonary arrest can save a patient's life. An ambulance driver as one of the ambulance personnel should be equipped with the two forms of skills above. The aim of community service is to increase the capacity of ambulance drivers in terms of providing basic life support skills and patient transportation to improve patient safety. This training was held in September 2019, at the H. Adam Malik General Hospital Training Center Installation Medan, with 24 participants. The training is carried out with 2 methods, namely exposure to BHD theory and BHD skills training. The knowledge and skills of participants before and after the training were assessed. Pre and post assessment results were analyzed using paired t-test with a significance level of p <0.05 Ambulance drivers in the Medan Tuntung and Medan Sunggal area are mostly over 30 years old, with most working as ambulance drivers for more than 5 years. The most recent level of education is high school graduation or equivalent. The results of statistical analysis using paired t-test, obtained a significant difference in the knowledge of ambulance drivers about basic life support theory before and after training (p = 0.000). Likewise, ambulance driver skills in providing basic life support for adult patients, infants and children were significantly different before and after training (p = 0.000). Training in basic life support skills and patient transportation can increase the capacity of ambulance drivers in providing basic life support..

Improved basic life support skills and patient transportation at ambulance drivers in Medan Tuntung and Medan Sunggal area to improve patient safety Yetty Machrina; Siregar, Kamal Basri; Nuraiza Meutia; Gema Nazri Yanni; Yunita Sari Pane
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 2 (2019): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

The technique of providing basic and quick life support (BHD) and transportation to patients with cardiac and pulmonary arrest can save a patient's life. An ambulance driver as one of the ambulance personnel should be equipped with the two forms of skills above. The aim of community service is to increase the capacity of ambulance drivers in terms of providing basic life support skills and patient transportation to improve patient safety. This training was held in September 2019, at the H. Adam Malik General Hospital Training Center Installation Medan, with 24 participants. The training is carried out with 2 methods, namely exposure to BHD theory and BHD skills training. The knowledge and skills of participants before and after the training were assessed. Pre and post assessment results were analyzed using paired t-test with a significance level of p <0.05 Ambulance drivers in the Medan Tuntung and Medan Sunggal area are mostly over 30 years old, with most working as ambulance drivers for more than 5 years. The most recent level of education is high school graduation or equivalent. The results of statistical analysis using paired t-test, obtained a significant difference in the knowledge of ambulance drivers about basic life support theory before and after training (p = 0.000). Likewise, ambulance driver skills in providing basic life support for adult patients, infants and children were significantly different before and after training (p = 0.000). Training in basic life support skills and patient transportation can increase the capacity of ambulance drivers in providing basic life support..

PROFILE OF SINONASAL TUMOR PATIENT IN ADAM MALIK GENERAL HOSPITAL 2016-2018 Ulya, Ulfatul; Ashri Yudhistira; Rambe, Andrina Y.M; Yetty Machrina
Sumatera Medical Journal Vol. 3 No. 3 (2020): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v3i3.3682

Abstract. Sinonasal tumor is a neoplasm that arises from nasal and paranasal sinus tissue. It is rarely found, only <3% of all malignancy in head and neck, and 1% of all malignancy in the body. Although it is rarely found, it can cause serious complication in adult. Unspecific sign and symptoms of sinonasal tumor often make the patients ignore the disease. It leads to the diagnosis of this disease becomes late and the patients come to the doctor in advanced stage. This research was conducted to know about the profile of sinonasal tumor patients in H. Adam Malik Medan Hospital on 2016-2018. The study was a descriptive study with retrospective approach. The data used are secondary data taken from medical records. The data were analyzed using a statistical application programs. Sinonasal tumor patients in RSUP HAM Medan are 158 patients, where 95 patients met the inclusion criteria, consisting of 24 benign tumors (25,3%) and 71 malignant tumors (74,7%). The majority of patients are male (71,6%), and the highest age group in in 51-60 years old (31,6%). The main complaints felt by the patients were nasal symptoms (64,2%), the location of tumors mostly found in nasal cavity (50,5%), the most histopathological type is NKSCC (43,2%), the most occupation is self-employment (26%), and the treatment of the patients are surgery (29,5%). Keyword: Sinonasal Tumor, Profile, Sinonasal Cancer

Effect of Exercise Intensity in Glut4 Expression on Type 2 Diabetes Mellitus Rat Rahmi, Rahmi; Machrina, Yetty; Yamamoto, Zulham
Media Ilmu Keolahragaan Indonesia Vol 11, No 2 (2021): December 2021
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/miki.v11i2.34222

Glucose transporter4 (GLUT4) is the main glucose transporter in skeletal muscle. Impaired GLUT4 expression plays a role in the disorders of glycemic homeostasis such as Type- 2 Diabetes Mellitus (T2DM). Exercise can increase the GLUT4 expression in skeletal muscles so that glucose can get into the cells faster. The intensity of exercise is an important factor in reducing blood glucose levels in patients with T2DM. This study used stored biological material of gastrocnemius muscle from 15 T2DM models of Wistar rats. Rats were divided into three treatment groups namely P0 (no exercise, control), P1 (moderate-intensity continuous exercise), and P2 (vigorous-intensity continuous exercise), and treated for 8 weeks. Glut4 expression was determined by real time-PCR. The relative expression of the Glut4 gene was calculated using the Livak formula. Moderate-intensity exercise increased Glut4 expression by 2.39 times while vigorous-intensity exercise increased Glut4 expression 2.56 times compared to control. The vigorous-intensity continuous exercise expressed higher Glut4 expression than the moderate- intensity continuous one.

Salat Dhuha Improves Blood Pressure: A Randomized Controlled Trial Boy, Elman; Lelo, Aznan; Tarigan, Amira Permatasari; Machrina, Yetty; Yusni, Yusni; Harahap, Juliandi; Sembiring, Rosita Juwita; Syafril, Santi; Sumartiningsih, Sri
Media Ilmu Keolahragaan Indonesia Vol 11, No 2 (2021): December 2021
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/miki.v11i2.34225

The prevalence of hypertension increases with age, more than 1 in every two elderly has hypertension, dominated by women. The primary prevention of hypertension is a worldwide public health concern. Salat dhuha is a moderate-intensity physical activity. Salat 2 movement cycles demonstrated improved systolic and diastolic blood pressure in adults. Our study purpose was to assess the effect of 2 and 8 movement cycles (rakaat) of salat dhuha to improve systolic and diastolic blood pressure in healthy Muslim elderly women. Muslim elderly women in a government senior residence (aged 60-74 years) participated in a 6 weeks controlled trial. We completed formal physical, clinical, and blood assessments before admission. Participants with hypertension history were excluded. The participants were randomized into 2 groups. The intervention group performed 8 rakaat of salat dhuha (n=13) and the control group performed 2 rakaat of salat dhuha (n=13). Two participants were dropped out of this study. At baseline and at the end of 6 weeks, a blood pressure examination is recorded. Parametric and nonparametric methods were used to analyze the data. The baseline characteristics of the two groups of participants were homogeneous. Compared to the control, the 8 rakaat of salat dhuha achieved a significant reduction in systolic and diastolic blood pressure (P0.05) at the end of the 6-weeks period. The findings show that salat dhuha has significant potential to improve blood pressure.

PENGARUH LATIHAN AEROBIK TERHADAP ASAM LAKTAT DAN SKALA BORG ATLET SEPAKBOLA Aditya Candra; Gusbakti Rusip; Yetty Machrina
Media Kesehatan Masyarakat Indonesia Vol. 12 No. 1: MARET 2016
Publisher : Faculty of Public Health, Hasanuddin University, Makassar

Kadar asam laktat yang tinggi pada atlet akan memberikan dampak negatif karena akan mempercepat kelelahan. Skala Borg digunakan untuk menilai tanggapan yang dirasakan. Penelitian ini bertujuan untuk mengetahui pengaruh latihan aerobik dapat menurunkan asam laktat dan skala borg. Penelitian yang dilakukan merupakan penelitian kuasi eksperimental dengan rancangan eksperimen ulang non-random. Penelitian dilakukan untuk membandingkan kadar asam laktat dan skala borg sebelum dan sesudah program latihan pada tiga kelompok, yaitu kelompok perlakuan latihan aerobik intensitas ringan (LAIR), kelompok latihan aerobik intensitas sedang (LAIS) dan kelompok kontrol. Penelitian dilaksanakan di stadion sepakbola Harapan Bangsa Banda Aceh dengansubjek atlet sepakbola PPLP Dispora Aceh. Rerata kadar asam laktat ketiga kelompok menunjukkan perbedaan. Penurunan asam laktat setelah uji latih yang bermakna terlihat pada kelompok dengan LAIS (p=0,04). Rerata skala Borg ketiga kelompok menunjukkan perbedaan. Penurunan nilai scoring skala Borg setelah uji latih yang berbeda bermakna terlihat pada kelompok dengan LAIS (p=0,012) dan LAIR (p=0,008). Latihan aerobik yang dilakukan dengan intensitas, durasi dan frekuensi yang tepat dapat meningkatkan performa dan prestasi atlet.

Pengaruh Latihan Aerobik Intensitas Ringan dan Sedang terhadap Kelelahan Otot (Muscle Fatique) Atlet Sepakbola Aceh Aditya Candra; Gusbakti Rusip; Yetty Machrina
JURNAL KEDOKTERAN DAN KESEHATAN Vol 3, No 1 (2016)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Kelelahan selama berolahraga menjadi suatu masalah yang dapat mengakibatkan terpuruknya suatu prestasi. Kondisi ini menjadi permasalahan yang sering dihadapi para atlet pada saat bertanding karena kekurangan cadangan energi dan tingginya kadar asam laktat di dalam darah. Penelitian ini bertujuan untuk mengetahui pengaruh latihan aerobik intensitas ringan dan sedang dapat memperlambat kelelahan selama berolahraga pada atlet sepakbola aceh. Penelitian kuasi eksperimental dengan rancangan eksperimen ulang non-random (non randomized pretest-posttest with control group design). Penelitian dilakukan untuk membandingkan kadar asam laktat perifer , waktu uji latih sampai lelah dan skala Borg (persepsi rasa sesak dan kaki lelah) sebelum dan sesudah program latihan pada 3 kelompok, yaitu kelompok perlakuan latihan aerobik intensitas ringan (LAIR), kelompok latihan aerobik intensitas sedang (LAIS) dan kelompok kontrol. Penelitian dilaksanakan di stadion sepakbola Harapan Bangsa Banda aceh. Subjek penelitian adalah atlet sepakbola Dispora Aceh yang tergabung dalam PPLP. Penurunan asam laktat setelah uji latih yang bermakna terlihat pada kelompok dengan LAIS (p= 0,04). Rerata waktu lelah ketiga kelompok menunjukkan perbedaan. Peningkatan waktu lelah setelah uji latih yang berbeda bermakna terlihat pada kelompok dengan LAIS (p = 0.009). Rerata skala borg sesak ketiga kelompok menunjukkan perbedaan. Penurunan nilai scoring skala borg sesak setelah uji latih yang berbeda bermakna terlihat pada kelompok dengan LAIS (p = 0.000). Rerata skala borg kaki lelah ketiga kelompok menunjukkan perbedaan. Penurunan nilai scoring skala borg kaki lelah setelah uji latih yang berbeda bermakna terlihat pada kelompok dengan LAIS (p = 0.012) dan LAIR (p = 0.008). Latihan aerobik yang dilakukan dengan intensitas, durasi dan frekuensi yang tepat dapat meningkatkan performa dan prestasi atlet. Pada penelitian ini menunjukkan latihan aerobik intensitas sedang dapat berpengaruh dalam memperlambat kelelahan selama berolahraga pada atlet sepakbola Aceh.

Polimorfisme Gen Leptin -2548G>A (Rs7799039) Pada Penderita Diabetes Mellitus Tipe 2 Edwin - Lewis; Yetty Machrina
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Vol.9 No.1 Mei 2023
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v9i1.10799

Diabetes Mellitus Tipe 2 merupakan penyakit metabolik dengan penyebab multifaktorial dari akibat pengaruh lingkungan berupa gaya hidup, pola makan yang salah, kurangnya berolahraga, pekerjaan dan baru-baru ini ditemukan adanya variasi gen atau polimorfisme gen yang bertanggung-jawab dalam peningkatan faktor resiko terjadinya Diabetes Mellitus Tipe 2 yaitu polimorfisme gen leptin -2548G>A (rs7799039). Tujuan literrature review ini untuk mengetahui polimorfisme gen leptin -2548G>A (rs7799039) pada penderita diabetes mellitus tipe 2. Metode yang digunakan adalah metode electronical database yaitu pencarian jurnal menggunakan Google scholar, Research gate, Science direct, Pubmed pada 5 tahun terakhir dari tahun 2018 sampai tahun 2023 dengan kata kunci bahasa Indonesia diabetes mellitus tipe 2, gen leptin -2548G>A, polimorfisme, teknik PCR-RFLP. Dari pencarian jurnal didapati ada 6 artikel yang sesuai dengan tujuan literrature review dan memenuhi kriteria inklusi yaitu penderita DM tipe 2 terkontrol, berumur 35-60 tahun, tanpa komplikasi. Untuk menganalisa polimorfisme gen leptin -2548G>A digunakan teknik PCR-RFLP. Hasil: adanya polimorfisme gen leptin -2548G>A pada penderita diabetes mellitus tipe 2 dimana allel A yang terdapat pada genotype AA dan GA dihubungkan dengan terjadinya polimorfisme gen leptin -2548G>A pada penderita diabetes. Diskusi: kami menemukan adanya artikel yang menyatakan tidak adanya hubungan yang signifikan polimorfisme gen leptin -2548G>A pada penderita diabetes yang disebabkan adanya perbedaan etnis atau ras yang diperiksa. Perlu adanya penelitian pada populasi masyarakat yang lebih luas dengan banyak sampel penderita diabetes.

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