Claim Missing Document
Check
Articles

Found 6 Documents
Search

KAJIAN PERESEPAN OBAT ANTIBIOTIK PENYAKIT ISPA PADA ANAK DI RSU ANUTAPURA PALU TAHUN 2017 Tandi, Joni
PHARMACON Vol 7, No 4 (2018): Pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.7.2018.21519

Abstract

KAJIAN PERESEPAN OBAT ANTIBIOTIK PENYAKIT ISPA PADA ANAK DI RSU ANUTAPURA PALU TAHUN 2017Joni Tandi1, Mufidah Penno1), Valen Ruterlin2), Ardiyanto Panggeso2)1)Program Studi S1 Farmasi, STIFA Pelita Mas Palu2)RSUAnutapura Palu, Sulawesi TengahEmail:jonitandi757@yahoo.comABSTRACTThis study aims to examine and to get a picture of the pattern of antibiotic used by patients with ARI in children who underwent inpatient at RSU Anutapura Palu and know the rationale of the use of antibiotic drug ARI disease in children who underwent inpatient at RS Anutapura Palu. This research was descriptive with prospective data collecting from October to December year 2016 to patient of urinary tract infection at inpatient installation of AnutapuraPalu Hospital which fulfill inclusion criteria. Sampling technique with purposive sampling, and was administered on 38 patients. The results showed the most widely used antibiotics were ceftriaxone (73.69%), cefotaxime (21.05%) and cefixime (5.26%). with accuracy of antibiotics based on 100% accurate parameter, 100% precise drug, proper dose covering precise dosage 71,05%, precise frequency 55,26% and precise duration of giving 15,79% and 100% patient right.Keywords: Study, Antibiotics, Acute Respiratory InfectionsABSTRAKPenelitian ini bertujuan untuk Mengetahui dan memperoleh gambaran mengenai pola penggunaan antibiotik pasien ISPA pada anak yang menjalani rawat inap di RSU Anutapura Palu dan Mengetahui kerasionalan penggunaan obat antibiotik penyakit ISPA pada anak yang menjalani rawat inap di RS Anutapura Palu. Penelitian ini berupa penelitian deskriptif dengan pengumpulan data dilakukan secara prospektif dari bulan Juni sampai Agustus tahun 2017 terhadap pasien infeksi saluran pernapasan akut di instalasi rawat inap Rumah Sakit Umum Anutapura Palu yang memenuhi criteria inklusi. Teknik pengambilan sampel dengan Purposive Sampling, dan diperoleh sampel sebanyak 38 pasien. Hasil penelitian menunjukkan Antibiotik yang paling banyak digunakan adalah ceftriaxone 73,69%, cefotaxime 21,05% dan cefixime 5,26 %. ketepatan pemberian antibiotik berdasarkan parameter tepat indikasi 100 %, tepat obat 100 %, tepat dosis yang meliputi tepat besaran dosis 71,05%, tepat frekuensi 55,26% dan tepat durasi pemberian 15,79% serta tepat pasien 100%. Kata Kunci : Kajian, Antibiotik, Infeksi Saluran Pernapasan Akut
TINJAUAN POLA PENGOBATAN GASTRITIS PADA PASIEN RAWAT INAP RSUD LUWUK Tandi, Joni
PHARMACON Vol 6, No 3 (2017): Pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.6.2017.17753

Abstract

TINJAUAN POLA PENGOBATAN GASTRITIS PADA PASIEN RAWAT INAP RSUD LUWUK  Joni Tandi11)Program Studi S1 Farmasi, STIFA Pelita Mas PaluEmail:Stifapelitamaspalu@yahoo.co.id ABSTRACT Iit has been done a research about the Treatment of Gastritis review to Patients. Hospitalized In Luwuk General Hospital. Of the research  is the aim which were to find out the pattern of the Treatment of Gastritis Patients Hospitalized at General Hospital Area Of Luwuk by looking at data about drug use on the patient record on the Medic gastritis. The origin of the research was gastritis patients hospitalized at general hospital area of Luwuk. While the sample of research were some of the patients which were taken according to which were the methods of gastritis sampling technique quota sampling. The parameters used were based on the percentage of drug dose, fulfil indication, accuracy of the drug and the side effects of the drug. Result of the study show that the percentage of drug use based on indications that match 100%, the percentage of drug use based on the exact dose appropriate 92,77%, the percentage of drug use based on the precision of the appropriate remedy, the percentage of use of 97,59% based on drug side effects according to 97,59%.  Keywords: Gastritis Remedy ABSTRAK Telah dilakukan penelitian tentang Tinjauan Pola Pengobatan Gastritis Pada Pasien Rawat Inap Rumah Sakit Umum Daerah Luwuk, dengan tujuan untuk mengetahui pola pengobatan gastritis pada pasien rawat inap di Rumah Sakit Umum Daerah Luwuk dengan melihat data tentng obat yang digunakan pada pasien gastritis pada bagian rekam medik. Populasi penenlitian adalah pasien penderita gastritis rawat inap pada. Sedangkan yang menjadi sampel penelitian adalah beberapa pasien gastritis yang diambil berdasarkan metode sampling dengan tekhnik quota sampling . parameter yang digunakan adalah persentase kedesuaian obat berdasarkan dosis, indikasi, ketepatan obat dan efek samping obat. Hasil studi menunjukkan bahwa persentase penggunaan obat berdasarkan tepat indikasi yang sesuai  100%, persentase penggunaan obat berdasarkan tepat dosis yang sesuai 92,77%, persentase penggunaan obat berdasarkan ketepatan obat yang sesuai 97,59%. Persentasepenggunaan obat berdasarkan efek samping obat yang sesuai 97,59%. Kata kunci: Obat Gastritis      
Effect Of Ethanol Extract Of Kenikir (Cosmos caudatus Kunth.) Leaves in Blood Glucose, Cholesterol and Histopathology Pancreas of Male White Rats (Rattus norvegicus) Tandi, Joni; Claresta, Jong A.; Ayu, Gusti; Irwan, Irwan
Indonesian Journal of Pharmaceutical Science and Technology Suppl 1, No. 1 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (540.307 KB) | DOI: 10.15416/ijpst.v1i1.17247

Abstract

The aim of this study was to investigate the effects extract of Kenikir in male rats parameters blood glucose, cholesterol and histopathological of the pancreas. Thirty rats were divided into six groups, and each group consists of five individuals with the details of groups I, II, and III as control groups and groups IV, V, and VI for the experiments. Group I: normal control was given NaCMC 0,5%; Group II: control negative was given Streptozotocin 30 mg/kgBW i.p, high feed fat 25 g/day, and the positive control was given met form in 45 mg/kgBW, and the experimental groups were each given extract of the kenikir leaves with dose 100 mg/kg BW, 200 mg/kgBW , and 400 mg/kg BW. The results showed that there were secondary metabolites contained in the extract of leaves of kenikir. Giving the extract of kenikir leaves at the dose of 200 mg/kg is effective in lowering the blood glucose levels, extract of leaves of kenikir with the dose of 400 mg/kg is effective to reduce the total cholesterol levels and regenerate pancreatic tissue, and extract of leaves of kenikir with the dose of 100 mg/kg BW did not give any maximum impacts to decrease the blood glucose. Keywords: Cholesterol, diabetic, histopathology, kenikir leaves ethanol extract
Pengaruh Pengobatan ARV terhadap Peningkatan Limfosit Pasien HIV-AIDS di Rumah Sakit Pemerintah Kota Palu Ruterlin, Valen; Tandi, Joni
Indonesian Journal of Clinical Pharmacy Vol 3, No 1 (2014)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (745.423 KB) | DOI: 10.15416/ijcp.2014.3.1.30

Abstract

 Berdasarkan laporan unit rekam medik sebuah rumah sakit pemerintah di Kota Palu periode Januari–Agustus 2010 terdapat 12 pasien yang didiagnosis sebagai positif HIV-AIDS. Etiologi penyakit ini ditandai dengan berat badan menurun, diare kronik yang berlangsung lebih dari 1 bulan, demam berkepanjangan lebih dari 1 bulan, infeksi saluran pernapasan bagian bawah yang parah atau menetap. HIV-AIDS merupakan penyakit yang disebabkan oleh retrovirus yang menyerang sel darah putih (limfosit) sehingga menurunkan sistem kekebalan tubuh. Penelitian ini bertujuan untuk mengetahui pengaruh pengobatan antiretroviral (ARV) pada peningkatan limfosit di rumah sakit pemerintah Kota Palu. Metode pengumpulan data dilakukan secara retrospektif pada Januari–Juni 2013 dan analisis hasil data menggunakan metode deskriptif nonparametik. Hasil penelitian menunjukkan terdapat peningkatan yang signifikan terhadap limfosit dengan kombinasi obat staviral (NRTI), efavirenz (NNRTI), dan duviral (NRTI), hiviral (NRTI), neviral (NNRTI) pada pasien awat jalan yang positif HIV-AIDS. Dengan demikian dapat disimpulkan bahwa pemberian ARV berpengaruh pada peningkatan limfosit sehingga akan meningkatkan sistem kekebalan tubuh pasien HIV-AIDS.Kata kunci: Antiretroviral (ARV), HIV-AIDS, sel limfositMedicational Influence of ARV with Increasing Limfosit of HIV-AIDS’s Patient at Public Hospital in PaluBased on medical records of a public hospital in Palu period January to August 2010, there were 12 patients who diagnosed HIV-AIDS positive. The etiology of the disease is characterized by weight loss, chronic diarrhea more than one month, fever more than one month, lower respiratory tract infections are severe or persistence. HIV-AIDS is a disease caused by a retrovirus that attacks white blood cells (lymphocytes), which decreasing the immune system. The aim of this study was to determine the effect of antiretroviral treatment (ARV) with increasing lymphocytes at a public hospital in Palu. Data were collected and retrospective analysis were conducted using a nonparametik descriptive method during January–Juny 2013. The results showed that there was a significant increasing on the white blood cells lymphocytes) with a combination of drugs staviral (NRTIs), efavirenz (NNRTI), and combivir (NRTIs), hiviral (NRTIs), neviral (NNRTIs) in outpatient with HIV-AIDS positive. It can be concluded that theeffect on the increase in ARV lymphocytes will increase the immune system of patients with HIV-AIDS.Key words: Antiretroviral (ARV), HIV-AIDS, limphocyte cells
UJI EFEK KOMBINASI EEDS DAN DPW TERHADAP PENURUNAN KADAR KOLESTEROLTOTAL DAN GLUKOSA DARAH TIKUSPUTIH JANTAN HIPERKOLESTEROLEMIA-DIABETES Tandi, Joni; Na'i, Alpina; Basilingan, Aprince
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol 2, No 1 (2019)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (583.794 KB) | DOI: 10.35799/pmj.2.1.2019.23607

Abstract

UJI EFEK KOMBINASI EEDS DAN DPW TERHADAP PENURUNAN KADAR KOLESTEROLTOTAL DAN GLUKOSA DARAH TIKUSPUTIH JANTAN HIPERKOLESTEROLEMIA-DIABETES Joni Tandi1), Alpina Na’i1), Aprince Basilingan1)1)Program Studi S1 Farmasi, STIFA Pelita Mas PaluEmail :jonitandi757@yahoo.com  ABSTRACT The study aimed to investigate the effect of combination on EEDS soursop extract ethanol and ethanol extract of EEDPW fragrant pandan leaves, lowering total cholesterol and blood glucose in male white rats induced high cholesterol and streptozotocin and did not cause toxicity in mice and determine the dose of EEDS and EEDPW leaf which effectively decreases total cholesterol and blood glucose levels in male white rats. This research is a laboratory experiment using posttest randomized controlled group design with posttest randomized control design with 8 treatment groups consisting of 5 test animals. Group 1 (normal control). group 2 (negative control) was given a NaCC Na suspension of 0.5% w / v. Group 3 positive (simvastatin suspension) and (metformin suspension). Group 4 was given EEDS 150 mg / kg BW. Group 5 was given EEDPW 600 mg / kg BW. Group 6 was given a combination of (I) EEDS, EEDPW 150 + 600 mg / kg BW. Group 7 was given a combination of (II) EEDS, EEDPW 75 + 300 mg / kg BW. The results showed that; there is a secondary metabolite compound in soursop leaf extract and pandan wangi, EEDS combination, EEDPW can decrease total cholesterol and blood glucose level, the most effective dose in decreasing the concentration of soursop leaves leaf sole 150 mg / kg BW. While the most effective dose is a combination (II) EEDS and EEDPW with a dose of 75 + 300 mg / kg BW, giving the maximum effect on decreased blood glucose levels. Keywords:.High Cholesterol Feed, Streptozotocin, Annona muricata L, Pandanus amarylifollius Roxb, Total Cholesterol  ABSTRAK Penelitian bertujuan untuk mengetahui efekkombinasi pada ekstraketanol daun sirsak EEDS dan ekstrak etanol daun pandan wangi EEDPW, penurunkan kadar kolesterol total danglukosa darah tikus putih jantan yang diinduksi pakan tinggi kolesterol dan streptozotocin dan tidak menimbulkan toksisitas pada tikus dan menentukan dosis berapa EEDS dan daun EEDPW yang efektif menurunkan kadar kolesterol total dan glukosa darah pada tikus putih jantan. Penelitian ini merupakan eksperimen laboratorium dengan menggunakan rancangan penelitian modifikasi posttest randomized controlled group design dengan 8 kelompok perlakuan yang terdiri dari 5 ekor hewan uji. Kelompok 1(kontrol normal) dan kelompok 2(kontrol negatif) diberi suspensi Na CMC 0,5% b/v. Kelompok 3 kontrol positif (suspensi simvastatin) dan (suspensi metformin). Kelompok 4 diberiEEDS 150 mg/kg BB. Kelompok 5 diberiEEDPW 600 mg/kg BB. Kelompok 6 diberi kombinasi (I) EEDS, EEDPW 150+600 mg/kg BB. Kelompok 7 diberi kombinasi (II) EEDS, EEDPW 75+300 mg/kg BB. Hasil penelitian menunjukkan bahwa;terdapat senyawa metabolit sekunder pada ekstrak daun sirsak dan pandan wangi,pemberian kombinasi EEDS, EEDPWdapat menurunkan kadar kolesterol total dan kadar gluosa darah, dosis yang paling efektif dalam penurunan kadar koleserol daun sirsak dosis tunggal 150 mg/kg BB.Sedangkan dosis paling efektif adalah kombinasi (II) EEDS  dan EEDPW dengan dosis 75+300 mg/kg BB, memberikan efek maksimal terhadap penurunan kadar glukosa darah. Kata Kunci : Pakan Tinggi Kolesterol, Streptozotocin, Annona muricata L,Pandanus amarylifollius Roxb, Kolesterol Total 
TOTAL FLAVONOID DAN EFEKTIVITAS EKSTRAK ETANOL BIJI KELOR (MORINGA OLEIFERA L) ASAL KOTA PALU SULAWESI TENGAH TERHADAP HISTOPATOLOGI PANKREAS TIKUS PUTIH JANTAN (RATTUS NORVEGICUS) YANG DIINDUKSI STREPTOZOTOCIN Anggi, Viani; Tandi, Joni; Veronika, Veronika
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (632.35 KB)

Abstract

This study aims to determine the content of flavonoid and the effect of ethanol extract of moringa seeds on the regeneration of pancreatic ? cells in male white rats streptozotocin induced diabetes. This study method used has total flavonoid equivalent quercetin by spectrophotometry uv-vis and to regeneration of pancreatic ? cells in male white rats used 30 test animals,namely male white rats divided into 6 groups, each group consisted of 5 male white rats with details of group I as normal control, Group II as negative control given 0.5% Na-CMC suspension, Group III as positive control given glibenclamide suspension and in Groups IV, V, and VI were given with each dose of 100 mg/kg BW, 200 mg/kg BW and 400 mg/kg BB. Histopathological damage picture of the pancreas was observed by staining HE using a 400x magnification olympus Cx21 microscope. The results showed that the ethanol extract of moringa seeds contained secondary metabolites, namely flavonoids, alkaloids, saponins and tannins. The results showed has total flavonoid equivalent quercetin of moringa seeds is 1,26% and regeneration of pancreatic ? cells in male white rats streptozotocin induced diabetes of Moringa seed ethanol extract at a dose of 400 mg/kg BB can have an effect on the regeneration of ? cells in the pancreas of white diabetic male rats.