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All Journal As-syifaa Jurnal Farmasi Window of Health : Jurnal Kesehatan
St Maryam, St
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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ANALISIS BAHAN KIMIA OBAT NATRIUM DIKLOFENAK PADA SEDIAAN JAMU PEGAL LINU YANG BEREDAR DI MAKASSAR Tahir, Masdiana; Maryam, St; Wahdania, Andi
Window of Health : Jurnal Kesehatan Vol. 1 No. 4 (Oktober, 2018)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (614.233 KB)

Abstract

Jamu pegal linu merupakan salah satu produk obat tradisional yang banyak diminati oleh masyarakat, karena dapat menghilangkan nyeri otot dan tulang, memperlancar peredaran darah, memperkuat daya tahan tubuh serta menghilangkan sakit diseluruh badan. Salah satu bahan kimia obat yang sering ditambahkan dalam jamu pegal linu adalah natrium diklofenak. Penelitian ini bertujuan untuk menganalisis kandungan bahan kimia obat natrium diklofenak pada sediaan jamu pegal linu. Jamu pegal linu yang digunakan pada penelitian ini yaitu 7 macam merek jamu pegal linu yang beredar di kota Makassar. Dengan kriteria jamu yang paling banyak diminati oleh masyarakat. Analisis kualitatif bahan kimia obat natrium diklofenak dilakukan dengan kromatografi lapis tipis (KLT), menggunakan fase diam silika gel dan  fase gerak etil asetat : asam asetat glasial : toluen (60:40:1). Hasil analisis menunjukkan sampel A, C dan G positif mengandung natrium diklofenak dengan nilai Rf sama dengan standar natrium diklofenak yaitu Rf= 0,69. Analisis kuantitatif secara spektrofometri UV-Vis pada panjang gelombang 280 nm dengan variasi konsentrasi 4, 6, 8, 10, 12, 14, dan 16 ppm, diperoleh kadar natrium diklofenak untuk sampel jamu A dengan kadar 154 mg/g, sampel C 28,302 mg/g, dan sampel G 6,908 mg/g. Kata kunci :     Natrium diklofenak, jamu pegal linu, Spektrofotometri UV-Vis
ANALISIS BAHAN KIMIA OBAT NATRIUM DIKLOFENAK PADA SEDIAAN JAMU PEGAL LINU YANG BEREDAR DI MAKASSAR Tahir, Masdiana; Maryam, St; Wahdania, Andi
Window of Health : Jurnal Kesehatan Vol. 1 No. 4 (Oktober, 2018)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (614.233 KB) | DOI: 10.33368/woh.v1i4.101

Abstract

Sore herbal medicine is one of the traditional medicine products that many people interested in due to it can eliminate the muscle pain and arthritis, accelerate blood circulation, strengthen body endurance and eliminate pain through out the body. One of the medicinal chemicals which is commonly added in thesore herbal medicine is diclofenac sodium. This study aimed to analyze the chemical content of diclofenac sodium drug in the sore herbal medicine dosage fom. There were 7 herbal medicine this research is 7 kinds of brand circulating in Makassar city with the criteria most demand by the society. Qualitative analysis of the diclofenac sodium drug was conducted by thin layer chromatography (TLC), used silica gel stationary phase and the mobile phase of ethyl acetate : gacial acetic acid : toluene (60:40:1). The result showed that A, C and G positive sample contain dicklofena sodium with Rf value equal to diclofenac sodium standard, Rf = 0,69. The quantitative analysis by UV-Vis spectrophotometry at the wavelength 280 nm with variation of concentration 4, 6, 8, 10, 12, 14 and 16 ppm was obtained diclofenac sodium content for sample A with 154 mg/g, for C 28,302 mg/g and sample G 6,908 mg.g. Keyword: Diclofenac Sodium, Rheumatic Paint, Spectrophotometry UV-Vis
ANALISIS KADAR FENOLIK FRAKSI ETIL ASETAT DAUN PETAI CINA (Leucaena leucocephala) (Lam.) de Wit) SECARA SPEKTROFOTOMETRI Uv-Vis Sari, Intan Purnama; Abidin, Zainal; Maryam, St
Jurnal Ilmiah As-Syifaa Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v12i2.681

Abstract

Traditionally, river tamarind leaves (Leucaena leucocephala (Lam.) De Wit.) can be used as medicine for injuries, swollen, diarrhea and also as antiseptic. The river tamarind leaves contains several main compounds such as alkaloids, saponins, flavonoids, phenols, mimosine, lectin, protein, oil, calcium, phosphorus, iron, vitamin A and vitamin B. The research aimed to determine the phenolic levels found in the ethyl acetate fraction of the leaves. The extraction was done by maceration method using ethanol 96% then fractionated with ethyl acetate solvent. The obtained fraction was analysed by UV-Vis spectrophotometry method at the maximum wavelength of 761 nm using gallic acid as a standard. Based on the qualitative test, river tamarind leaves positively contained phenolic. The phenolic compound contained in the ethyl acetate fraction was 0.176 mgGAE/g in that every gram of ethyl acetate fraction had phenolic of 0.176 mg equivalent to garlic acid.
Co-Authors Intan Purnama Sari Masdiana Tahir, Masdiana Wahdania, Andi Wahdania, Andi Zainal Abidin