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All Journal JEJAK Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Mochammad Yusuf, Mochammad
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Health Professions Medicine & Pharmacology Neuroscience

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Effect of Dyslipidemia Therapy on Creatinine Kinase Activity Level in Patients with Heart Disease Sulistian, Waode Dila; Fuadi, Muhamad Ro’biul; Edijanto, Soebagijo Poegoeh; Yusuf, Mochammad
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 27, No 2 (2021)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v27i2.1631

Abstract

Cardiovascular disease remains a significant health problem in the Asia Pacific region. Several studies have found that dyslipidemia is a cause of morbidity and mortality and requires high medical costs. Dyslipidemia is a risk factor for atherosclerosis. The most widely used therapy for dyslipidemia is statins. Statins often cause muscle disorders such as myalgia, myopathy, and rhabdomyolysis, which can cause death. A prospective cohort study design was carried out at Airlangga University Hospital, Surabaya, from April to November 2019. A total of 26 sample pairs containing 13 samples were treated with Atorvastatin, and 13 samples were treated with Simvastatin. The subjects were examined for the creatinine kinase activity level using enzymatic methods. The mean creatinine kinase levels in the atorvastatin group before and after treatment was 105.71 IU/L and 100.03 IU/L, respectively, because the subjects were diagnosed with acute coronary syndromes and blood was collected during acute conditions. Median creatinine kinase levels in the Simvastatin group were 85.5 IU/L before therapy and 118.1 IU/L after therapy, indicating significant differences in creatinine kinase levels before and after treatment. Simvastatin is very susceptible to certain drug interactions that can increase the concentration of statins in the serum. There were differences in levels of creatinine kinase activity before and after Simvastatin therapy but not Atorvastatin.
Indonesian Food Production Challenges: Climate, Land and Industrialization Setiawan, Avi Budi; Nugroho, Agus Dwi; Wiyanti, Dian Tri; Yusuf, Mochammad; Maslikhatun, Anjani; Bowo, Prasetyo Ari
JEJAK: Jurnal Ekonomi dan Kebijakan Vol 16, No 1 (2023): March 2023
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jejak.v16i1.43334

Abstract

The increase in agricultural production has become a global issue related to food security. Indonesia faces challenges in fulfilling its food needs. Climate change, land conversion, and industrialization play a role in food crop production. This study aims to examine the short-term and long-term effects of climate change, land conversion, and industrialization on the food production index. The analysis method used is the Autoregressive Distributed Lag (ARDL). The ARDL analysis was chosen because it can explain the short-term and long-term effects as well as the effects at each lag time. The results showed that there is positive and significant long-term cointegration or influence between rainfall, per capita energy consumption, agricultural land area, and forest area on the food production index. There is also a significant negative long-term effect between air temperature, industrialization, and population density on the food production index. In the short term, the previous year's food production, land area and forest area, air temperature, energy consumption, rainfall in two and three years ago, current of industrial share, and one and two years ago industrial share, population density two years ago influence the current food production index. The conclusion and findings of this study are that there is long-term cointegration and short-term effects at different lag times for climate change, land conversion, and industrialization variables on the food production index.
Co-Authors Agus Dwi Nugroho, Agus Dwi Avi Budi Setiawan Dian Tri Wiyanti Fuadi, Muhamad Ro’biul M. Amin Maslikhatun, Anjani MOCHAMMAD THAHA Prasetyo Ari Bowo, Prasetyo Ari Soebagijo Poegoeh Edijanto Sulistian, Waode Dila Wenny P Nilamsari, Wenny P