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Formulasi and Evaluasi Stabilitas Fisik Suspensi Ubi Cilembu (Ipomea batatas L.) dengan Suspending Agent CMC Na dan PGS Sebagai Antihiperkolesterol Fitriani, Yeyen Nor; INHS, Cikra; Yuliati, Ninis; Aryantini, Dyah
Jurnal Farmasi Sains dan Terapan Vol 2, No 1 (2015)
Publisher : Jurnal Farmasi Sains dan Terapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (329.887 KB) | DOI: 10.33508/jfst.v2i1.699

Abstract

Drug which has small solubility in water is one of the problems that cause instability of pharmaceutical preparations. One drug practically insoluble in water is cilembu (Ipomoea batatas L.). So cilembu (Ipomoea batatas L.) made in form of suspension in order to produce stable preparations in liquid form. Making of the suspension cannot be separated from the suspending agent. CMC Na (Carboxymethylcellulose Sodium) and PGS (pulvis gummosus) is suspending agent which have been studied to produce a stable suspension. Accordingly, this study was conducted to know the suspension evaluation stability cilembu (Ipomoea batatas L.) with a suspending agent CMC Na and PGS as antihypercholesterol. Method of manufacture is dispersion method. Evaluation of physical stability test was conducted on the organoleptic, homogeneity, pH, density, viscosity, sedimentation volume, and redispersion. Data were analyzed with repeated measures and shelflife. Evaluation of physical stability the suspension cilembu with a suspending agent CMC Na and PGS on observations organoleptic, homogeneity, density and redispersion showed no difference, while the pH, viscosity and sedimentation volume were not significant differences (p< 0.05) during 30 days of storage.
OPTIMALISASI PEMANFAATAN TOGA SEBAGAI ANTIKOLESTEROL MELALUI PEMBERDAYAAN IBU RUMAH TANGGA DI DESA BAKALAN KECAMATAN GROGOL KABUPATEN KEDIRI. Aryantini, Dyah; Kusumaratni, Dyah Ayu; Indriana, Indriana
Journal of Community Engagement and Empowerment Vol 3, No 1 (2021)
Publisher : Institut Ilmu Kesehatah Bhakti Wiyata Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tanaman Obat Keluarga (TOGA) merupakan sumber daya alam keanekaragaman hayati yang khasiat dan manfaatnya telah diketahui masyarakat Indonesia secara tradisional. Seiring dengan meningkatnya IPTEK, taraf ekonomi serta pengetahuan tentang obat-obatan, kerap kali masyarakat beralih ke obat-obatan dokter karena mempercayai obat kimia yang teruji khasiatnya secara laboratorium. Dibanding dengan obat tradisional, tidak banyak masyarakat yang tau bahwa telah banyak tanaman herbal yang juga telah teruji secara klinis. Pemberdayaan ibu rumah tangga di Desa bakalan dalam mengoptimalkan pemanfaatan TOGA dikhususkan pada TOGA yang berkhasiat untuk mencegah kolesterol tinggi. Adapun tujuan kegiatan ini adalah untuk meningkatkan pengetahuan ibu-ibu tentang jenis TOGA antikolesterol dan menambah ketrampilan dalam memanfaatkan TOGA tersebut dalam bentuk jamu dan sebagainya. Hal ini dikarenakan tidak banyak masyarakat yang tahu bahwa TOGA yang selama ini dibudidayakan di pekarangan mereka sebenarnya berpotensi sebagai jamu antikolesterol tinggi. Kegiatan ini menggunakan metode ceramah, demonstrasi dan analisa data dilakukan berdasarkan hasil isian angkat baik sebelum dan sesudah penyuluhan. Hasilnya 62% dari 30 orang peserta telah menguasai materi tentang jenis TOGA antikolesterol tinggi dan hasil demonstrasi menunjukkan antusiasme peserta untuk mengaplikasikan TOGA antikolesterol sebagai jamu untuk mengurangi penggunaan obat kimia.
GAMBARAN KARAKTERISASI DARI EKSTRAK ETANOL LIMBAH RAMBUT JAGUNG MANIS (Zea mays L.) Sholicha, Yuyun Nikmatus; Sari, Fita; Aryantini, Dyah
As-Syifaa Jurnal Farmasi Vol 13, No 2 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i2.719

Abstract

Traditional plants in Indonesia, have a variety of benefits to overcome various diseases. For example, sweet corn hair waste (Zea mays L), was the residue from corn which is usually used for culinary purposes. Corn silk in previous studies was thought to have pharmacological activity as anti-inflammatory, antidiabetic, and antihypertensive. This study aims to determine the characterization of the ethanol extract of sweet corn hair waste in a hilly area of Kediri, East Java. Characterization to determine the content of active compounds in the ethanol extract of sweet corn hair waste and to ensure the quality of corn hair waste extract when it will be used as raw material for traditional medicine. Characterization includes specific parameters such as screening for metabolites in plant extracts using Thin Layer Chromatography (TLC) and non-specific parameters including determination of water content and specific gravity. The sample used was ethanol extract of sweet corn hair waste (EELRJM) obtained from the hilly area of Kediri, East Java. The results of the specific parameters of the secondary metabolite compound test by TLC indicated that EELRJM contains quercetin compounds of the flavonoid group. Non-specific parameters resulted that the water content of EELRJM did not meet the requirements of the extract monograph because it was suspected that there was an influence on the weather including rainfall.