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Correlation between serum leptin concentration and disease activity in normal body mass index premenopausal women with systemic lupus erythematosus Suarjana, I Nyoman; Kasjmir, Yoga I; Isbagio, Harry; Soegondo, S
Indonesian Journal of Rheumatology Vol 1, No 1 (2009)
Publisher : Indonesian Rheumatology Association

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Abstract

Background. Leptin is recognized as a cytokine-like hormone with pleiotropic actions in modulating immune responses. The role of leptin in pathogenesis of systemiclupus erythematosus (SLE) was not fully understood yet. Previous study did not fi nd the correlation between serum leptin concentration and disease activity in patients with SLE, but selection of the subjects wasn’t based on the classifi cation of body mass index (BMI) and menopausal status.Objective. To determine correlation between serum leptin concentration and the disease activity in normal BMI premenopausal women with SLE.Methods. Serum leptin concentration was measured by enzyme-linked immunosorbent assay and disease activity was scored using Mexican SLE disease activity index (Mex-SLEDAI). Spearman’s correlation coeffi cient test was used for evaluating the strength of association between leptin level and Mex-SLEDAI score.Results. Seventy normal BMI premenopausal women with SLE were included in this study. The median of serum leptin concentration was 13.4 (0.6 – 45.9) ng/ml.The median serum leptin concentration in patients with active disease was 12.4 (0.6 – 41.6) ng/dl, whereas in patients with inactive disease was 15.2 (3.9 – 45.9) ng/dl.No signifi cant different was found between serum leptin concentration in active and inactive disease (p = 0.14). A weak negative correlation was observed between leptinconcentration and Mex-SLEDAI score, but not statistically signifi cant (r = -0.22; p = 0.07).Conclusion. No correlation was found between serum leptin concentration and disease activity in normal BMI premenopausal women with SLE. Prednisone doses anddisease duration might interfere.
Role of leptin in the pathogenesis of systemic lupus erythematosus Suarjana, I Nyoman
Indonesian Journal of Rheumatology Vol 1, No 1 (2009)
Publisher : Indonesian Rheumatology Association

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Abstract

Leptin is a 16 kDa adipocyte-secreted hormone that regulates weight centrally and links nutritional status to neuroendocrine and immune functions. Several studies indicate that leptin plays an important role in immune responses. Leptin affects both innate and adaptive immunity. It can stimulate dendritic cells (DC), monocytes, macrophages, neutrophils and natural killer cells. Leptin is involved in DC maturation and survival,and can skew the cytokine balance of a T helper (Th)1 profi le. In adaptive immunity, leptin can promote naïve T cell survival and production of interferon-γ and interleukin-2, and activate Th1 cells while inhibiting Th2 cells. Leptin may play an important role in theregulation of the Th1/Th2 balance. As a survival factor, leptin has been shown to suppress B cell apoptosis. The role of leptin in the pathogenesis of systemic lupuserythematosus (SLE) is not fully determined yet. This review tries to link the role of leptin in immunity to the pathogenesis of SLE.
Knee arthritis in an HIV positive patient - not associated with antiretroviral therapy Suarjana, I Nyoman; Kasjmir, Yoga I; Setiyohadi, Bambang
Indonesian Journal of Rheumatology Vol 1, No 1 (2009)
Publisher : Indonesian Rheumatology Association

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Abstract

Human immunodefi ciency virus (HIV)-associated arthritis is an oligoarthritis which predominantly affect the knees and ankles. It tends to be selflimited and to last less than six weeks. However, some patients with HIV-associated arthritis have been reported to have a disease course of more than six weeks with joint destruction. Synovial fl uid cultures are typically sterile and radiographs of the affected joints are usually normal except in those rare patients with a prolonged duration of symptoms in whom joint-space narrowing can occur.1,2 The pathophysiology of HIV specific arthritis types is not fully understood but drugs of the highly active antiretroviral therapy, in particular indinavir, are supposed to cause arthritis or rheumatological complaints.3 However,recently both human T-lymphotropic virus (HTLV) type I and HTLV-II have been suggested to induce infl ammatory or autoimmune reactions which can increase signifi cantly the incidence of arthritis.4 We report a patient with HIV infection presenting as knee arthritis which was apparently not associated with antiretroviral therapy.
PELATIHAN LARI SPRINT JARAK 20 METER 5 REPETISI 4 SET DAN 10 REPETISI 2 SET TERHADAP KECEPATAN LARI SPRINT 100 METER SISWA PUTRA PESERTA EKSTRA ATLETIK SMP NEGERI 4 MENGWI TAHUN PELAJARAN 2015/2016 Antara, Wisnu; Yasa, Putu Merta; Suarjana, Nyoman
Jurnal Pendidikan Kesehatan Rekreasi Vol 3 No 1 (2017): Januari 2017
Publisher : Jurnal Pendidikan Kesehatan Rekreasi

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Abstract

Berdasarkan pengamatan di lapangan bahwa daya lari sprint siswa putra peserta ekstra atletik SMP Negeri 4 Mengwi dalam melakukan kegiatan olahraga khususnya dalam pertandingan dan perlombaan belum menunjukkan hasil yang maksimal, oleh karena pelatihan lari sprint terhadap siswa sering diabaikan, bahkan pelatihan yang dilakukan oleh siswa kurang berorientasi pada sepuluh komponen biomotorik yang menentukan prestasi olahgara di sekolah sehingga nampak lari sprint siswa kurang memuaskan. Dari hal itu dilakukan pelatihan lari sprint jarak 20 meter 5 repetisi 4 set dan 10 repetisi 2 set terhadap kecepatan lari sprint 100 meter siswa putra peserta ekstra atletik SMP Negeri 4 Mengwi Tahun Pelajaran 2015/2016. Jumlah populasi 30 orang siswa, semua populasi digunakan sebagai sampel. Dengan teknik undian sampel dibagi menjadi 2 kelompok yaitu kelompok I sebanyak 15 orang yang diberi Pelatihan lari sprint jarak 20 meter 5 repetisi 4 set dan kelompok II sebanyak 15 orang yang diberi pelatihan Pelatihan lari sprint jarak 20 meter 10 repetisi 2 set.
IKLAN LAYANAN KESEHATAN MASYARAKAT (ILKM): KAJIAN SEMIOTIK Suwitra, I Made; Suarjana, Nyoman
Kajian Linguistik dan Sastra Vol 5, No 1 (2020)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (11356.992 KB) | DOI: 10.23917/kls.v5i1.7142

Abstract

Public health service advertisements (PHSA) tend to provide information, remind, add value, influence, and even change people's attitudes to healthy living. The purpose of this study was to determine the style of language, meaning, and public health service advertising ideology. The results of this study showed that; (1) the Public Health Service Ads (PHSA) language style, (2) the diction or word choice used tends to be informal, general, brief and understandable by ordinary learned societies. Regarding the tone contained, the narrative text had a simple language style, usually suitable to give instructions, commands, lessons, lectures, and the like. From the meaning point of view, semiotic meaning came from the relation between signifier and signified or it was the meaning of connotation. The ideology that lied behind sourced from the resulting connotation. The way to express imperatively as well as the use of symbols, colors, backgrounds (sign) such as thermometers; for instance. This has determined that PHSA concerned with hygiene, health, precautions, caution, caring, togetherness, planning, prosperity, and happiness.Keywords: PHSA, language style, meaning, ideology
Tingkat daya ledak otot tungkai siswa putra peserta ekstrakurikuler bolavoli Sekolah Menengah Pertama Santika, I Gusti Putu Ngurah Adi; Subekti, Maryoto; Sudiarta, I Gusti Ngurah; Sugianta, I Wayan; Suarjana, I Nyoman
Jurnal Ilmu Keolahragaan Vol 4, No 2 (2021): Jurnal Ilmu Keolahragaan Volume 4 Nomor 2 Tahun 2021
Publisher : Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/jilo.v4i2.52297

Abstract

Tujuan dari penelitian ini adalah untuk mengetahui tingkat daya ledak tubuh peserta ekstra kutikuler bolavoli SMP Nageri 1 Mengwi di masa pandemi covid-19. Jumlah sampel dalam penelitian ini adalah 34 orang yang diambil dengan teknik Populasi Study dengan mengambil keseluruhan peserta yang berjumlah 34 orang. Hasil penelitian menunjukkan bahwa pada tinggi raihan nilai minimumnya adalah 190 cm dan maksimumnya 222 cm serta dengan rerata 203,59±6,942 cm. untuk Tinggi loncatan diperoleh nilai minimum 215 cm dan maksimum 270 cm serta nilai rerata 238,94±11,062 cm. sedangkan untuk hasil pengukuran diperoleh nilai minimum 8 cm dan maksimum 60 cm serta rerata 36,35±10,366 cm. Berdasakan pembahasan diatas, maka dapat di simpulkan bahwa tingkat daya ledak siswa putra peserta ektrakulikuler bolavoli SMP Negeri 1 Mengwi tergolong cukup.
PKM GERMAS di Sekolah Dasar Negeri 2 Medahan, Kecamatan Blahbatuh, Kabupaten Gianyar Ni Putu Widya Astuti; Nyoman Suarjana
JURNAL PENGABDIAN KEPADA MASYARAKAT Vol 10, No 1 (2020): Juli 2020
Publisher : LPPM UNINUS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30999/jpkm.v10i1.730

Abstract

The GERMAS (Gerakan Masyarakat Hidup Sehat or healthy-live society program)  is a government program as an effort to increase the level of public health. Healthy living behavior should be instilled as early as possible. The implementation priority of GERMAS is for the elementary school. Medahan 2 Elementary School is one of the elementary schools in Medahan Village, Blahbatuh District, Gianyar Regency. Students and teachers at Medahan 2 Elementary School share common problems that are not yet aware of the GERMAS and PHBS programs. In addition, the lack of supporting facilities that are feasible for PHBS implementation is an obstacle in the implementation of the GERMAS program, especially on environmental cleanliness and the use of coloring agents in food. It is expected that after socialization and training, there will be an increased knowledge about the GERMAS program, improved implementation of physical activities, elevated consumption of natural dyes and environmentally hygiene foods, increased knowledge of PHBS, improved knowledge on the proper hand washing method, and improved quality of supporting facilities for school environment cleanliness. The results of this dedication showed an increase in PHBS facilities, especially hand washing places for elementary school students in  Medahan 2 Elementary School. Educational activities on GERMAS, especially environmental hygiene and food without harmful chemicals increased student knowledge by 92.3%. The hand washing method was increased by 89.5% at the end of GERMAS program.  
PELATIHAN LARI SPRINT JARAK 20 METER 5 REPETISI 4 SET DAN 10 REPETISI 2 SET TERHADAP KECEPATAN LARI SPRINT 100 METER SISWA PUTRA PESERTA EKSTRA ATLETIK SMP NEGERI 4 MENGWI TAHUN PELAJARAN 2015/2016 Wisnu Antara; Putu Merta Yasa; Nyoman Suarjana
Jurnal Pendidikan Kesehatan Rekreasi Vol. 3 No. 1 (2017): Januari 2017
Publisher : Program Studi Pendidikan Jasmani Kesehatan dan Rekreasi FKIP Universitas PGRI Mahadewa Indonesia bekerjasama dengan Asosiasi Prodi Olahraga Perguruan Tinggi PGRI (APOPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (111.468 KB)

Abstract

Berdasarkan pengamatan di lapangan bahwa daya lari sprint siswa putra peserta ekstra atletik SMP Negeri 4 Mengwi dalam melakukan kegiatan olahraga khususnya dalam pertandingan dan perlombaan belum menunjukkan hasil yang maksimal, oleh karena pelatihan lari sprint terhadap siswa sering diabaikan, bahkan pelatihan yang dilakukan oleh siswa kurang berorientasi pada sepuluh komponen biomotorik yang menentukan prestasi olahgara di sekolah sehingga nampak lari sprint siswa kurang memuaskan. Dari hal itu dilakukan pelatihan lari sprint jarak 20 meter 5 repetisi 4 set dan 10 repetisi 2 set terhadap kecepatan lari sprint 100 meter siswa putra peserta ekstra atletik SMP Negeri 4 Mengwi Tahun Pelajaran 2015/2016. Jumlah populasi 30 orang siswa, semua populasi digunakan sebagai sampel. Dengan teknik undian sampel dibagi menjadi 2 kelompok yaitu kelompok I sebanyak 15 orang yang diberi Pelatihan lari sprint jarak 20 meter 5 repetisi 4 set dan kelompok II sebanyak 15 orang yang diberi pelatihan Pelatihan lari sprint jarak 20 meter 10 repetisi 2 set.
IMPLEMENTASI MODEL PEMBELAJARAN KOOPERATIF TIPE NHT (NUMBERED HEAD TOGETHER) UNTUK MENINGKATKAN HASIL BELAJAR TEKNIK DASAR PASSING PERMAINAN SEPAK BOLA I Kadek Yudha Pranata; I Ketut Sumerta; I Putu Merta Yasa; Ni Luh Putu Indrawathi; I Wayan Sugianta; I Nyoman Suarjana
Jurnal Pendidikan Kesehatan Rekreasi Vol. 6 No. 1 (2020): Januari 2020
Publisher : Program Studi Pendidikan Jasmani Kesehatan dan Rekreasi FKIP Universitas PGRI Mahadewa Indonesia bekerjasama dengan Asosiasi Prodi Olahraga Perguruan Tinggi PGRI (APOPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (297.862 KB) | DOI: 10.5281/zenodo.3661581

Abstract

Penelitian ini bertujuan untuk meningkatkan hasil belajar teknik dasar pasing permainan sepak bola melalui penerapan model pembelajaran kooperatif tipe NHT (Numbered Head Together) pada siswa kelas VIII B SMP Widya Sakti Denpasar tahun pelajaran 2018/2019. Subjek penelitian ini adalah siswa kelas VIII B SMP Widya Sakti Denpasar berjumlah 40 orang, data dianalisis menggunakan analisis statistik deskriptif. Berdasarkan hasil penelitian didapatkan hasil belajar teknik dasar pasing permainan sepak bola secara klasikal pada observasi awal 68,08, meningkat pada siklus I menjadi 77,09 dan meningkat pada siklus II menjadi 86,1. Berdasarkan hasil analisis data dan pembahasan, disimpulkan bahwa hasil belajar teknik dasar passing permainan sepak bola meningkat melalui penerapan model pembelajaran kooperatif tipe NHT pada siswa kelas VIII B SMP Widya Sakti Denpasar tahun pelajaran 2018/2019.
PUBLIC HEALTH SERVICE ADVERTISEMENT (PHSA); SEMIOTIC ANALYSIS I Made Suwitra; Nyoman Suarjana
SEMIOTIKA: Jurnal Komunikasi Vol 12, No 1 (2018): Semiotika : Jurnal Komunikasi
Publisher : Universitas Bunda Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30813/s:jk.v12i1.1541

Abstract

ABSTRAK Iklan layanan kesehatan masyarakat (ILKM) cenderung bertujuan untuk memberikan informasi, mengingatkan, menambah nilai, memengaruhi, dan bahkan mengubah sikap masyarakat untuk hidup sehat. Tujuan dari penelitian ini yaitu untuk mengetahui bagaimana gaya bahasa, makna, dan ideologi iklan layanan kesehatan masyarakat (ILKM). Hasil penelitian ini menunjukan bahwa; Gaya bahasa Iklan Layanan Kesehatan Masyarakat (ILKM), secara diksi atau pilihan kata yang digunakan cenderung bersifat tak resmi, bentuknya umum, singkat dan dapat dipahami oleh masyarakat terpelajar biasa. Dilihat dari sudut nada, narasi teks memiliki gaya bahasa sederhana, biasanya cocok untuk memberi instruksi, perintah, pelajaran, perkuliahan, dan sejenisnya. Dari sisi makna, secara semiotik pemaknaan muncul dari hubungan antara penanda (signifier) dan petanda (signified) atau pemaknaan konotasi. Ideologi yang melatarbelakangi bersumber pada konotasi yang dihasilkan. Penyampaian secara imperatif dan pemakaian simbol, warna, latar temperatur (tanda) misalnya, termometer. Hasil penelitian ini menemukan bahwa ILKM berkenaan dengan kebersihan, kesehatan, kewaspadaan, kehati-hatian, kepedulian, kebersamaan, perencanaan, kesejahteraan, dan kebahagiaan.Kata kunci: ILKM, gaya bahasa,makna, ideologi