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All Journal Jambi Medical Journal "Jurnal Kedokteran dan Kesehatan" Jurnal Kedokteran Brawijaya Indonesian Journal of Tropical and Infectious Disease MEDISAINS Global Medical and Health Communication MEDIC MEdical Dedication Electronic Journal Scientific of Environmental Health And Diseases
Humaryanto, Humaryanto
Jambi University
Dentistry Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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Gambaran Indeks Massa Tubuh dan Densitas Massa Tulang sebagai Faktor Risiko Osteoporosis pada Wanita Humaryanto, Humaryanto; Syauqy, Ahmad
Jurnal Kedokteran Brawijaya Vol 30, No 3 (2019)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2019.030.03.10

Abstract

Osteoporosis merupakan suatu kondisi kelainan yang ditandai penurunan densitas massa tulang dengan risiko mikrofraktur, terutama fraktur pinggul. Faktor risiko osteoporosis diantaranya adalah indeks massa tubuh (IMT) yang rendah. Penelitian ini bertujuan untuk membuktikan hubungan antara IMT dan status densitas massa tulang (DMT) pada 347 orang wanita dewasa di kota Jambi pada tahun 2017 melalui pemeriksaan Ultrasound bone densitometry. Penelitian dilakukan dengan rancangan penelitian observasional analitik dengan pendekatan cross-sectional. Sampel penelitian terbanyak pada kelompok IMT normal 37,2% dengan hasil DMT pada kelompok osteoporosis 48,7%. Hasil penelitian menunjukkan bahwa pada kelompok obesitas memiliki nilai DMT osteoporosis yang lebih banyak dibandingkan kelompok lainnya namun tidak ada hubungan yang bermakna secara statistik antara IMT dengan DMT (p=0,132). 
EFFECT OF GREEN COFFEE BEANS EXTRACT OINTMENTS FOR WOUND HEALING Humaryanto, Humaryanto; Rahman, Ave Olivia
Jurnal Kedokteran Brawijaya Vol 30, No 3 (2019)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2019.030.03.1

Abstract

Some interventions, such as coffee powder, are applied on wound to facilitate healing process. Coffee has several properties that can facilitate wound healing. Application of Robusta coffee bean ointment 22.5 % on full thickness wound could increase  fibroblast. Povidone iodine 10% has remained popular as wound antiseptic. This study aimed to evaluate the effect of green coffee bean extract in lower concentration for healing wound in rats. This study used male Sprague Dawley rats, 10 rats in each group. The skin incision was held in right back of rats with a diameter of 1.5 cm under lidocaine anesthetic subcutaneously. Group I was not given intervention, group II was given liquid povidone iodine 10%, and group III was given 15% green coffee bean extract in vaseline base. Interventions were held every day without wound debridement. Wound size was measured at day 0, 7 and 16.  Animals were sacrificed at day 7 (proliferative phase) and 16 (remodeling phase). Sections were stained using Haematoxilyn-eosin. Histopathology assessment of wound tissue is on reepithelization and presence of: inflammatory cells, fibroblast, collagen, and vascularization. Green coffee extract could  increase wound contraction  and  accelerated wound healing. Histopathology result on day 7 showed that green coffee extract had high response inflammatory cells and fibroblast. The provision of 15% green coffee bean extract ointment can accelerate wound healing  with higher inflammation response and fibroblast in proliferative phase .
Antidiabetic effect of Psychotria malayana Jack in induced type 1 diabetic rat Fairuz, Fairuz; Dewi, Hasna; Humaryanto, Humaryanto
MEDISAINS Vol 18, No 1 (2020)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v18i1.6909

Abstract

Background: Therapies for hyperglycemic treatment, including insulin and oral diabetes medications, have been confirmed to cause several side effects. Thus, finding new drugs with fewer side effects is of high importance. Salung leaf herb (Psychotria malayana Jack) reported used in traditional societies as a treatment for diabetes. However, the scientific proof of this plant for diabetes treatment is still lacking.Objective: To evaluate the antidiabetic effect of the P. malayana jack in induced type 1 diabetic rats by assessing blood glucose level and pancreatic cells in white rats.Methods: Alloxan used to induce type I diabetes. Rats randomly divided into six groups. A Group P1 received 250 mg/kg BW; group P2 received 500 mg/kg BW, group P3 received 1000 mg/kg BW. While group 4 basal received no treatment, group 5 received distilled water as a negative control, and group 6 received glibenclamide as a positive control. Medications are given for six days. Glucose levels were measured, and observation of pancreatic Langerhans cell damages.Results:  A decrease in blood glucose levels observed in all treatment groups. The most significant reduction (49.76%; 1000 mg/kg BW) occurred in the P3 group. Morphological features of pancreatic Langerhans cell damage were slightly high in the P1 group.Conclusion: P. malayana Jack can consider having an antidiabetic effect in a type 1 diabetic rat by reducing blood glucose levels.
Effect of essential oil on hypertrophic scars Rahman, Ave Olivia; Humaryanto, Humaryanto; Purwakanthi, Anati; Simanjuntak, Charles Apul
MEDISAINS Vol 19, No 1 (2021)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v19i1.10192

Abstract

Background: Hypertrophic scars are abnormal scars resulted from a disrupted wound healing process. Hypertrophic scars can affect the body aesthetic of the sufferers, but, on the other hand, conventional therapy has not been optimally effective. The application of essential oil combinations as an alternative therapy for hypertrophic scars has not been scientifically proven.Purposes: This study was to determine the effectiveness of the essential oil as a hypertrophic scar therapy.Methods: This study used a pre and post-test design. As many as 24 subjects aged 17-25 years with hypertrophic scars were given essential oil combinations every morning and evening for six months. Assessment of hypertrophic scars was done using the POSAS  (Patient and Observer Scar Assessment Scale).Results: The results showed that the POSAS score decreased after the essential oil combination administration for six months, 14.40±6.08 vs. 22.67±8.31 (p<0.001).Conclusion: the combination of essential oil oils used in this study reduces hypertrophic scars based on the POSAS assessment.
IDENTIFICATION OF SCCMEC TYPE IN ISOLATE OF METHICILLIN RESISTANT Staphylococcus aureus (MRSA) IN JAMBI BY USING POLYMERASE CHAIN REACTION (PCR) Humaryanto Humaryanto; Hanina Hanina; Lipinwati Lipinwati; Charles Apul Simanjuntak
Indonesian Journal of Tropical and Infectious Disease Vol. 8 No. 2 (2020)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v8i2.12691

Abstract

Staphylococcal cassette chromosome mec (SCCmec) is one of the mobile genetic elements of Methicillin-Resistant Staphylococcus aureus (MRSA) that carries many resistance genes and allows SCCmec to move from one bacterium to another. Twelve types of SCCmec have been identified throughout the world. Identification of SCCmec type is needed to determine the pattern of MRSA resistance in a particular region. This study aimed to identify the type of SCCmec MRSA from clinical samples. Specifically, this study was conducted at the Biomolecular Laboratory of the Faculty of Medicine and Health Sciences of Jambi University in June 2018-February 2019. Culture was carried out on 100 clinical specimens of festering wound swabs from inpatients at hopitals in Jambi City. A total of 32 samples of Staphytect plus test positive were tested using Cefoxitin disc diffusion method and MecA Polymerase Chain Reaction (PCR). There were 14 samples identified as MRSA isolates, namely twelve samples (85.72%) of SCCmec type III, one sample (7.14%) of SCCmec type II, and one sample (7.14%) of SCCmec type IVb. The results were different from previous studies where all MRSA isolates (100%) in Indonesia were SCCmec type III, although most SCCmec types were still dominated by SCCmec type III. This study concludes that there has been a shift in the content of SCCmec in MRSA isolate originating from hospitals in Jambi city.
Profil Ekspresi mRNA Gen Murine Double Minute2, Kruppel-Like Factor4, dan c-Myc pada Fibrosarkoma Humaryanto Humaryanto; M. Nurhalim Shahib; Yoni Fuadah Syukriani; Nucki Nursjamsi Hidayat
Global Medical & Health Communication (GMHC) Vol 5, No 1 (2017)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (122.231 KB) | DOI: 10.29313/gmhc.v5i1.1842

Abstract

Fibrosarkoma hanya terjadi 1–3% dari seluruh keganasan jaringan lunak. Hingga saat ini etiologi fibrosarkoma belum diketahui dengan pasti. Beberapa faktor dapat menjadi penyebab patogenesis fibrosarkoma antara lain radiasi, terpapar zat kimia tertentu, serta infeksi human herpes virus 8 (HHV8) dan Epstein-Barr virus (EBV). Penelitian terkini menunjukkan bahwa banyak sarkoma terkait dengan mutasi genetik. Penelitian ini bertujuan melihat profil ekspresi mRNA gen Krüppel-like Factor4, Murine Double Minute2, dan c-Myc pada fibrosarkoma menggunakan teknik real time PCR kuantitatif (quantitative real time PCR, qRT-PCR). Analisis data menggunakan metode kuantititatif relatif 2-ΔΔCt. Penelitian ini menggunakan 10 sampel kasus fibrosarkoma yang ditemukan di Kota Jambi dari tahun 2011–2015. Hasil ΔCt (+SD) MDM2, KLF-4, dan c-Myc disusun dari nilai yang terkecil hingga tertinggi adalah 1,85±2,14; 2,06±3,86; 2,9±2,66 secara berurutan. Dibanding dengan level ekspresi dengan GAPDH sebagai housekeeping gene, gen MDM2 dan KLF-4 relatif menurun dua kali lipat, sedangkan gen c-Myc relatif menurun lebih dari tiga kali lipat. Simpulan, penelitian ini menunjukkan bahwa pada kasus fibrosarkoma, gen c-Myc disupresi lebih kuat dibanding dengan gen MDM2 dan KLF-4.STUDIES ON MRNA GENE EXPRESSION OF MDM2, KLF4,AND C-MYC IN FIBROSARCOMAFibrosarcoma is a rare soft tissue sarcoma, reported only 1–3% of all soft tissue sarcomas. Like any other soft-tissue sarcomas the definitive caused has not yet understood. Recognized causes include exposure to ionizing radiation, various physical and chemical factors, infection with human herpes virus (HHV8) and Epstein-Barr virus (EBV). Current research indicates many sarcomas are associated with genetic mutations. In this study, we investigated profile of mRNA gene expression KLF4, MDM2, and c-Myc of RNA in fibrosarcoma cases. The genes expression was examined using quantitative real time PCR (qRT-PCR) and we analyzed the relative gene expression using the 2-ΔΔCt method. Ten samples of fibrosarcoma cases found in Jambi city from 2011 to 2015 were used. The three targeting genes were placed in the order from lowest to highest base on their ΔCt values compared to internal control genes using GAPDH genes. The results are as follows: MDM2 1.85±2.14, KLF-4 2.06±3.86, and c-Myc 2.9±2.66 respectively. A relative quantification by normalized target gene relative to GAPDH, describes the changes in expression of three genes. The status of MDM2 and KLF-4 were relatively decreased expression by 2 fold, and the states of c-Myc were relatively decreased by more than 3 fold. This suggest that in fibrosarcoma the c-Myc gene are suppressed stonger than those MDM2 and KLF-4 genes.
PENYULUHAN AWAM DAN PEMERIKSAAN KEPADATAN TULANG PADA MASYARAKAT UMUM SEBAGAI SKRINING AWAL OSTEOPOROSIS DI KECAMATAN MUARO TEMBESI JAMBI humaryanto humaryanto; erny kusdiyah; Asro Hayani Harahap
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 1 No. 2 (2018): MEDIC: Medical Dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/medicaldedication.v1i2.4938

Abstract

ABSTRAK Meningkatnya usia harapan hidup menyebabkan berbagai penyakit degeneratif dan metabolik, termasuk osteoporosis akan menjadi permasalahan muskuloskletal yang memerlukan perhatian khusus, terutama di negara-negara berkembang. Upaya penyuluhan dan skrining pada masyarakat mengenai osteoporosis sangat diperlukan dalam mengantisipasi peningkatan jumlah kasusnya dimasyarakat. Untuk itu pemohon bermaksud untuk melakukan suatu kegiatan berupa penyuluhan dan pemeriksaan osteoporosis serta melakukan konsultasi mengenai hasil dari skrining tersebut di kecamatan Muaro Tembesi Jambi sebagai salah satu bentuk kepedulian pemohon sebagai dosen dan tenaga kesehatan yang ada di Jambi. Kegiatan ini dilakukan dengan metode penyuluhan dan pemeriksaan langsung peserta, memberikan edukasi kepada peserta sesuai dengan hasil pemeriksaan kepadatan tulang. Pemeriksaan kepadatan tulang menggunakan alat densitometer yang mempunyai sensitivitas yang akurat. Lokasi kegiatan dilakukan di Kantor Camat Muaro Tembesi Jambi dan kegiatan ini diselenggarakan satu kali, pada hari Selasa 2 Agustus 2017. Jumlah peserta 124 orang. Peserta berjenis kelamin perempuan sebanyak 102 orang (82,25%), rerata usia 33 sampai 37 tahun dengan usia termuda 19 tahun dan usia tertua 63 tahun. Hasil pemeriksaan kepadatan tulang dengan cara melihat T-Score yang didapat. Hasil pengukuran kepadatan tulang berdasarkan usia, diketahui bahwa 55 (44,35%) peserta mengalami kecenderungan osteoporosis yakni dengan hasil T-Score yang didapat ≥ -2,5, 69 (55,64%) peserta mendapatkan T-Score < -2,5. Hasil pemeriksaan kepadatan tulang berdasarkan jenis kelamin diketahui bahwa perempuasn lebih cenderung terkena osteoporosis dibandingkan laki-laki. Semua peserta baik yang tidak merasakan keluhan pada tulang tetap dilakukan pemeriksaan kepadatan tulang dan berkonsultasi.
IDENTIFIKASI KASUS TOKSOPLASMOSIS DENGAN UJI AGLUTINASI LATEK DI PUSKESMAS TAHTUL YAMAN Humaryanto Humaryanto; Hanina Hanina; Susan Tarawifa
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 3 No. 1 (2020): MEDIC: Medical Dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/medicaldedication.v3i1.8579

Abstract

Infeksi Toxoplasma gondii dapat terjadi karena perolehan maupun kongenital, yang sering kali tidak menimbulkan gejala yang jelas atau sub klinis sehingga kebanyakan tidak disadari. Pada wanita yang terinfeksi Toksoplasma gondii, selama kehamilan dapat menyebabkan janin yang dikandung mengalami keguguran atau bayi lahir namun mengalami beberapa gangguan baik cacat fisik maupun nonfisik. Di Puskesmas Tahtul Yaman belum ada yang terdeteksi menderita Toksoplasmosis. Hal ini dapat dimengerti mengingat Toksoplasmosis umumnya tidak menimbulkan gejala. Dengan uji aglutinasi latek ini, diharapkan dapat diketahui angka kejadian Toksoplasmosis dan dapat ditindak lanjuti. Metode kegiatan yang dilakukan adalah berupa pemeriksaan darah terhadap 60 orang wanita usia subur dengan menggunakan uji aglutinasi latek. Hasil pemeriksaan menunjukkan mununjukkan terdapat 36 orang positif toxoplasmosis, 20 orang negatif dan 2 orang equivocal. Hasil positif toxoplasmosis paling banyak terdapat pada kelompok usia 30 sampai 39 tahun yaitu sebanyak 28 orang. Pada kelompok wanita yang sudah menikah terdapat 33 orang positif toxoplasmosis dan pada wanita yang pernah mengalami riwayat keguguran terdapat 22 orang positif toxoplasmosis
DETEKSI AWAL KAKI DATAR PADA PELAJAR SMP DI KOTA JAMBI Humaryanto Humaryanto; Patrick Patrick
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 4 No. 2 (2021): MEDIC. Medical dedication
Publisher : Universitas Jambi

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Abstract

ABSTRACT Flat feet (pes planus) are common in infants and children and often disappear before adulthood. Thus, flat feet are described as physiological because they are usually flexible, painless, and have no functional consequences. In rare cases, flat feet can become painful or stiff, which may be a sign of underlying foot pathology, including arthritis or tarsal coalitions. The earlier it is detected, the easier it is to make corrections, the faster the recovery of muscle and bone function, and the better the growth and development of a child. Efforts to screen flat feet in children can be done ink to assess the prints of the subject's feet. This activity is carried out by using counseling methods and examining the prints of the children's feet. The location of the activity was carried out in 8 randomly selected junior high schools in the city of Jambi. The total number of students suspected of having flat feet was 765 people with a prevalence of 17.99%. Students suspected of having flat feet were 374 women (48.89%), and 433 men (51.11%), ranging in age from 12 to 15 years with an average age of 14 years. All students suspected of flat feet will be subjected to further examination to confirm and measure the severity of flat feet. Keywords: Counseling, Flat feet, SMP ABSTRAK Kaki datar (pes planus) sering terjadi pada bayi dan anak-anak dan sering menghilang sebelum menginjak dewasa. Dengan demikian, kaki datar digambarkan sebagai fisiologis karena biasanya fleksibel, tidak nyeri, dan tidak memiliki konsekuensi fungsional. Dalam kasus yang jarang terjadi, kaki datar dapat menjadi menyakitkan atau kaku, yang mungkin merupakan tanda patologi kaki yang mendasarinya, termasuk radang sendi atau koalisi tarsal. Semakin dini terdeteksi, semakin mudah koreksi yang dilakukan, semakin cepat pemulihan fungsi otot dan tulang, serta semakin baik tumbuh kembangnya seorang anak. Upaya skrining kaki datar pada anak-anak dapat dilakukan tinta untuk menilai cetakan telapak kaki subjek. Kegiatan ini dilakukan dengan metode penyuluhan dan pemeriksaan cetakan telapak kaki anak. Lokasi kegiatan dilakukan di 8 SMP yang dipilih secara acak di kota Jambi. Jumlah total siswa yang dicurigai memiliki kaki datar sebanyak 765 orang dengan prevalensi sebesar 17,99%. Siswa yang diduga kaki datar berjenis kelamin perempuan sebanyak 374 orang (48,89%), dan laki-laki 433 orang (51,11%), rentang usia 12 sampai 15 tahun dengan rerata usia 14 tahun. Semua siswa yang dicurigai kaki datar akan dilakukan pemeriksaan lebih lanjut untuk memastikan dan mengukur derajat keparahan dari kaki datar. Kata Kunci: Penyuluhan, Kaki datar, SMP.
PELATIHAN PERUBAHAN PERILAKU DAN PENINGKATAN IMUNITAS DI ERA PANDEMI COVID-19 BAGI PARA GURU ANGGOTA PGRI DI KOTA JAMBI DAN KABUPATEN MUARO JAMBI Humaryanto Humaryanto; Mifftahurahmah Mifftahurahmah; Huntari Harahap; Putri Sari Wulandari
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 4 No. 2 (2021): MEDIC. Medical dedication
Publisher : Universitas Jambi

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Abstract

Abstract The world is under pressure from the Corona virus disease 2019 (Covid-19) pandemic since 2020. The impact of the pandemic is now beginning to spread to the world of education. Almost 18 months after schools in Indonesia were closed to curb the spread of COVID-19, limited face-to-face learning has been started. The health protocol must always be implemented by all school members and the role of the teacher is very important in this situation, especially regarding the correct use of masks. In addition, to maintain endurance, students and teachers must consume nutritious food and vitamins. Many original Indonesian herbal plants can be consumed as immune boosters. The objectives of this community service activity is to increase teacher knowledge in changing behavior and increasing immunity in the era of the Covid-19 pandemic. The method used is counseling and training through virtual webinar activity with topics on how to use, store, and dispose of mask waste, Covid-19 updates, herbal medicine, and nutrition in the Covid-19 era. This activity was attended by 54 teachers from Jambi City (46 people; 85.19%) and Muaro Jambi Regency (8 people; 14.81%). The participants of the activity consisted of elementary school teachers (72.22%), junior high school/MTs teachers (25.93%), and senior high school teacher (1.85%). This community service obtained the conclusion of counseling and training can increase the teacher knowledge in changing behavior and increasing immunity in the Covid-19 pandemic era. Keywords: Training, behavior change, immunity enhancement, Covid-19 ABSTRAK Dunia berada di bawah tekanan dari pandemi Corona Virus Disease 2019 (Covid-19) sejak tahun 2020. Dampak dari pandemic tersebut kini mulai merambah ke dunia pendidikan. Hampir 18 bulan setelah sekolah di Indonesia ditutup untuk menekan penyebaran Covid-19, pembelajaran tatap muka secara terbatas telah dimulai. Protokol kesehatan harus selalu dilaksanakan oleh seluruh warga sekolah dan peran guru sangat penting pada situasi ini, terutama mengenai penggunaan masker yang benar. Selain itu, untuk menjaga daya tahan tubuh, siswa dan guru harus mengkonsumsi makanan bergizi dan vitamin. Banyak tanaman-tanaman herbal asli Indonesia yang dapat dikonsumsi sebagai immune booster. Tujuan dari kegiatan pengabdian masyarakat ini adalah untuk meningkatkan pengetahuan guru dalam perubahan perilaku dan peningkatan imunitas di era pandemi Covid-19. Metode yang digunakan adalah penyuluhan dan pelatihan melalui kegiatan webinar virtual dengan topik cara penggunaan, penyimpanan, dan pembuangan limbah masker, update Covid-19­, herbal medicine, dan nutrisi di era Covid-19. Kegiatan ini dihadiri oleh 54 orang guru yang berasal dari Kota Jambi (46 orang; 85,19%) dan Kabupaten Muaro Jambi (8 orang; 14,81%). Peserta kegiatan terdiri dari guru SD (72,22%), guru SMP/MTs (25,93%), dan guru SMA/SMK (1,85%). Pengabdian masyarakat ini memperoleh simpulan, penyuluhan dan pelatihan dapat meningkatkan pengetahuan guru dalam perubahan perilaku dan peningkatan imunitas di era pandemi Covid-19. Kata kunci : Pelatihan, perubahan perilaku, peningkatan imunitas, Covid-19
Co-Authors Ahmad Syauqy Ahmad Syauqy Anati Purwakanthi, Anati Asro Hayani Harahap Aurora Wahyu Indah Dwi Ave Olivia Rahman Budi Justisia dewi, hasna Erny Kusdiyah Fairuz Quzwain Gading Patrick William Hanina Hanina Hanina, Hanina Huntari Harahap I Nyoman Sujana Ima Maria Lipinwati ., Lipinwati M. Nurhalim Shahib Miftahurrahmah Miftahurrahmah, Miftahurrahmah Nucki Nursjamsi Hidayat Patrick Patrick Patrick William Gading Putri Sari Wulandari Simanjuntak, Charles Apul Suzan, Raihanah Tarawifa, Susan Wahyu Indah Dewi Aurora Yoni Fuadah Syukriani