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Erratum: Chronic physical exercise increases a neurogenesis marker within hippocampus Zulkarnain, Mohammad; Flora, Rostika; Andrianti, Septi
Medical Journal of Indonesia Vol 27, No 3 (2018): September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (116.864 KB) | DOI: 10.13181/mji.v27i3.3172

Abstract

[This corrects the article DOI: 10.13181/mji.v27i2.1685]
Chronic physical exercise increases a neurogenesis marker within hippocampus Zulkarnain, Mohammad; Flora, Rostika; Andrianti, Septi
Medical Journal of Indonesia Vol 27, No 2 (2018): June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (349.964 KB) | DOI: 10.13181/mji.v27i2.1685

Abstract

Background:Aerobic and anaerobic physical exercises conducted in both acute and chronic are really essential in keeping the body especially brain healthy. Physical exercise plays an important role in molecular system and is beneficial for the brain by enhancing neurogenesis which is mediated by the increase of BDNF level. This study aimed to evaluate the effect of physical exercise to the BDNF level of hippocampus tissues in Wistar rats.Methods: Thirty male rats were divided into five groups i.e. control group, acute aerobic physical exercise group, acute anaerobic physical exercise group, chronic aerobic physical exercise group, and chronic anaerobic physical exercise group. Physical exercises were conducted on animal treadmill. The level of hippocampus BDNF was determined using ELISA. The data were analyzed using independent t-test.Results: BDNF average levels of chronic aerobic and anaerobic physical exercises were higher than those of acute ones (152.86±1.62 pg/ml and 122.22±1.53 pg/ml vs 59.38±6.10 pg/ml and 54.05±3.35 pg/ml). There were significant differences in the BDNF average levels of hippocampus tissues between aerobic and anaerobic groups, in both acute and chronic exercise.Conclusion: The chronic physical exercises, both aerobic or anaerobic, are increasing higher the level of BDNF in brain tissue.
RELATIONSHIP BETWEEN LUNG FUNCTION AND INTERLEUKIN-6 (IL-6) LEVELS IN THE POPULATION IN THE VICINITY OF THE GANDUS RUBBER FACTORY AND THE SUKAWINATAN WASTE DISPOSAL SITE IN PALEMBANG Adela, Novita; Zulkarnain, Mohammad; Flora, Rostika
Biomedical Journal of Indonesia Vol 5, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v5i1.7977

Abstract

Exposure to air pollution can interfere with the capacity of lung function and the body's immune system. Lung function capacity is the sum of two or more lung volumes. Interleukin-6 (IL-6) is an inflammatory mediator in respiratory pathogenesis. This study aims to determine the relationship between lung function and Interleukin-6 (IL-6) levels in the population around the Gandus Rubber Factory and Sukawinatan Landfill Palembang. The research design used is the type of correlation or explanatory that is examining the relationship between variables. A total of 72 samples were divided into 2 groups: groups in the Gandus Rubber Factory area and groups in the Sukawinatan Waste Disposal Site (Palembang). Lung function tests were measured using spirometry and Interleukin-6 levels were measured using ELISA examination. Chi square test results showed that there was no significant relationship (p value = 0.001) between lung function in the population around the Gandus Rubber Factory and Sukawinatan Waste Landfill. And there is no significant relationship (p value = 0.337) between Interleukin-6 (IL-6) levels in the population around the Gandus Rubber Factory and Sukawinatan Waste Landfill. Chi Square test results showed that there was no significant relationship (p value = 0.626) between lung function and Interleukin-6 (IL-6) levels in the population around the Gandus Rubber Factory. Chi Square test results showed that there was no significant relationship (p value = 1,000) between lung function and Interleukin-6 (IL-6) levels in the population around the Palembang Sukawinatan Landfill. Conclusions from the results of the study that there is no significant relationship (p <0.05) between levels of Interleukin-6 and Lung Function in the population around the Gandus Rubber Factory and Sukawinatan Landfill Palembang.
Hubungan Fungsi Paru dengan Kadar Interleukin-6 (Il-6) Pada Penduduk Yang Berada Di Sekitar Pabrik Karet Gandus Dan Tempat Pembuangan Akhir (Tpa) Sampah Sukawinatan Palembang Novita Adela; Mohammad Zulkarnain; Rostika Flora
Biomedical Journal of Indonesia Vol. 5 No. 1 (2019): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

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Abstract

Paparan dari polusi udara dapat mengganggu kapasitas fungsi paru dan sistem imum tubuh. Kapasitas fungsi parumerupakan penjumlahan dari dua volume paru atau lebih. Interleukin-6 (IL-6) merupakan mediator inflamasi padapatogenesis pernapasan. Penelitian ini bertujuan untuk mengetahui hubungan antara fungsi paru dan kadarInterleukin-6 (IL-6) pada penduduk yang berada di sekitar Pabrik Karet Gandus dan TPA Sukawinatan Palembang.Rancangan penelitian yang digunakan adalah jenis korelasi atau explanatory yaitu mengkaji hubungan antaravariabel. Sampel sebanyak 72 dan dibagi menjadi 2 kelompok : kelompok di wilayah Pabrik Karet Gandus dankelompok di wilayah Tempat Pembuangan Akhir (TPA) Sampah Sukawinatan Palembang. Uji fungsi paru di ukurmenggunakan spirometri dan kadar Interleukin-6 diukur menggunakan pemeriksaan ELISA. Hasil uji Chi squaremenunjukkan bahwa tidak terdapat hubungan yang bermakna (p value = 0,001) antara fungsi paru pada pendudukyang berada di sekitar Pabrik Karet Gandus dan TPA Sampah Sukawinatan. Dan tidak terdapat hubungan yangbermakna (p value = 0,337) antara kadar Interleukin-6 (IL-6) pada penduduk yang berada di sekitar Pabrik KaretGandus dan TPA Sampah Sukawinatan. Hasil uji Chi Square menunjukkan bahwa tidak terdapat hubungan yangbermakna (p value = 0,626) antara fungsi paru dan kadar Interleukin-6 (IL-6) pada penduduk yang berada di sekitarPabrik Karet Gandus. Hasil uji Chi Square menunjukkan bahwa tidak terdapat hubungan yang bermakna (p value =1,000) antara fungsi paru dan kadar Interleukin-6 (IL-6) pada penduduk yang berada di sekitar TPA SampahSukawinatan Palembang. Kesimpulan dari hasil penelitian bahwa Tidak terdapat hubungan yang bermakna(p<0,05) antara kadar Interleukin-6 dan Fungsi Paru pada penduduk yang berada di sekitar Pabrik Karet Gandusdan TPA Sukawinatan Palembang.
Nominal focus group discussion dalam penelitian di lingkup program studi dokter layanan primer Mohammad Zulkarnain; Dani Hilmanto; Meita Damayanti
JURNAL KEDOKTERAN DAN KESEHATAN Vol 4, No 1 (2017)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Saat ini pendidikan Dokter Layanan Primer (DLP) telah mulai dilaksanakan di Universitas Padjadjaran Bandung, dan nantinya akan segera dikuti oleh perguruan tinggi lain yang fakultas kedokterannya berakreditasi A. Tulisan ini dimaksudkan untuk memperkenalkan secara terperinci tentang penerapan Nominal Focus Group Discussion (NFGD) kuantitatif dalam pengambilan keputusan dalam kelompok-kelompok pengembangan DLP serta memperoleh umpan balik terhadap kelemahan dan keunggulan NFGD kuantitatif. Kegiatan NFGD untuk menentukan bobot penilaian dilakukan di Puskesmas Betung, Kecamatan Betung, Kabupaten Banyuasin, Propinsi Sumatera Selatan, dihadiri oleh sebanyak 14 orang. Bobot terendah diberikan kepada pertanyaan nomor 3  untuk meja 1 yang hanya 2,38, dan bobot tertinggi diberikan kepada pertanyaan nomor 2  untuk meja 3 dan kepada pertanyaan nomor 12 untuk meja 4, yaitu keduanya sama sebesar 4,54. Sedangkan untuk meja kegiatan, bobot penilaian terendah diberikan peserta terhadap meja 5 sebesar 2,69, yang merupakan tempat petugas kesehatan melakukan pelayanan kesehatan, sedangkan yang tertinggi untuk meja 2 dengan nilai maksimal 5, yaitu meja tempat penimbangan berat badan anak balita. Walapun NFGD kuantitatif masih sangat jarang digunakan dalam pengambilan keputusan kelompok, namun dalam penerapannya ternyata dapat dimengerti dan diterima dengan mudah oleh peserta diskusi kelompok dan waktu yang digunakan juga relatif lebih singkat dibandingkan dengan NFGD Kualitatif karena masing-masing peserta hanya perlu menuliskan angka, bukan kalimat-kalimat yang panjang sehingga dapat diprediksi bahwa NFGD kuantitaif ini bisa diterima untuk dikembangkan dalam pengambilan keputusan-keputusan berkelompok saat pengembangan program DLP di Indonesia.
PERBEDAAN KUALITAS HIDUP ANGGOTA TNI PEROKOK DAN BUKAN PEROKOK DI LINGKUNGAN AJENDAM II SRIWIJAYA PALEMBANG TAHUN 2017 Adhitya Pratama; Mohammad Zulkarnain; Eddy Roflin
Majalah Kedokteran Sriwijaya Vol 50, No 1 (2018): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v50i1.8532

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Perbedaan Kualitas Hidup Anggota TNI Perokok dan Bukan Perokok di Lingkungan Ajendam II Sriwijaya Palembang Tahun 2017. Merokok merupakan sebuah fenomena yang cukup kompleks dan telah menjadi kebiasaan yang membudaya di masyarakat. Di dalam rokok terdapat berbagai zat beracun yang sangat berbahaya bagi tubuh. Hal ini menjadikan kebiasaan merokok termasuk ke dalam penyebab kematian yang dapat dicegah. Lebih dari 1 miliyar perokok di dunia akan mengalami kematian akibat berbagai penyakit yang ada kaitannya dengan konsumsi tembakau seperti penyakit jantung, kanker, penyakit paru, dan lain–lain. Tingginya prevalensi merokok di Indonesia berdampak cukup signifikan terhadap kematian dini, akibatnya dapat menyebabkan pendeknya harapan hidup, meningkatnya biaya pengobatan penyakit akibat konsumsi rokok yang berkepanjangan, dan menurunya produktivitas.. Jenis penelitian yang akan dilakukan adalah penelitian analitik potong lintang dengan data primer dari data kuisioner anggota TNI di Ajendam II Sriwijaya Palembang tahun 2017.Analisis menggunakan Chy-Square didapatkan nilai p sebesar 0.000 < ? (alfa) 0.05. Terdapat hubungan yang signifikan antara merokok dan kualitas hidup
Safety And Health Implementation Study Work (K3) In Coal Mining Companies (Case Study: PT. XYZ) Arafik Arafik; Restu Juniah; Mohammad Zulkarnain
Indonesian Journal of Environmental Management and Sustainability Vol. 3 No. 3 (2019): September
Publisher : Research Centre of Inorganic Materials and Complexs

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (462.674 KB) | DOI: 10.26554/ijems.2019.3.3.75-79

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This study aims to analyze the implementation of occupational safety and health (K3) in the coal mining company PT XYZ, Analyze and identify the factors that influence the implementation of occupational safety and health (K3) in the mining company PT XYZ. This research is a descriptive qualitative and quantitative research approach. Primary data obtained from respondents are used as a means to obtain information or data carried out by field surveys through direct observation and interviews with respondents in the company and secondary data obtained from PT XYZ collected and compiled according to the problem of this study which was conducted in literature studies. Data were analyzed through text analysis, data interpretation. Data were analyzed using the SPSS (factor analysis) program to analyze the factors that influence the implementation of occupational safety and health in the coal mining company PT XYZ.
The Relation between the Characteristics of Parents and the Incidence of Stunting in Elementary School Children in the Working Area of the Air Beliti Health Center Dita Anggriani Lubis; Mohammad Zulkarnain; Rostika Flora; Risnawati Tanjung
Budapest International Research and Critics Institute (BIRCI-Journal): Humanities and Social Sciences Vol 4, No 3 (2021): Budapest International Research and Critics Institute August
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v4i3.2215

Abstract

Stunting is a failure of growth and development experienced by children due to inadequate nutritional intake for a long time, recurrent infectious diseases, and inadequate psychosocial stimulation. The incidence of stunting is higher in rural areas than in urban areas. This study aims to analyze the relationship between maternal characteristics and the incidence of stunting in elementary school children in the Air Beliti Health Center working area. The study was conducted on elementary school children in the working area of the Air Beliti Health Center, Musi Rawas Regency. The design of this study used a cross-sectional design, with a total sample of 84 respondents who were taken randomly and met the inclusion criteria. Determination of stunting is based on anthropometric measurements, while the characteristics of parents are assessed using a questionnaire. Furthermore, the data were analyzed using Univariate, Bivariate, and Multivariate statistical tests. The results of anthropometric measurements showed that children who experienced stunting were 41 people, 48.8%. Based on the characteristics of the parents, it was found that 54.8% of fathers and 50% of mothers had low education, 65.5% of fathers and 75% of mothers worked as farmers, 58.3% of parents had low economic status, and 51.2% parents marry at a young age. There is a significant relationship between married age (p = 0.049), maternal education (0.029), and stunting incidence. Based on the multivariate test results, it was found that the most dominant factor related to the incidence of stunting was the age at marriage (p = 0.000; OR = 80.079). Parents who marry in their teens have a risk of 80,079 times having stunting children. Conclusion: adolescent marriage is associated with the incidence of stunting in elementary school children in the work area of the Air Beliti Health Center.
Hubungan Stunting dengan Tingkat Keparahan Karies Gigi pada Anak Usia 10-12 Tahun di Kecamatan Tuah Negeri Kabupaten Musi Rawas Abubakar Lutfi; Rostika Flora; Haerawati Idris; Mohammad Zulkarnain
Jurnal Akademika Baiturrahim Jambi Vol 10, No 2 (2021): September
Publisher : Sekolah Tinggi Ilmu Kesehatan Baiturrahim Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36565/jab.v10i2.395

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Stunting is one of the most common malnutrition conditions. Stunting conditions can cause impaired child development including developmental disorders in the oral cavity. Stunting children are more susceptible to dental caries due to changes in saliva characteristics. This study aims to analyze the relationship between stunting and the severity of dental caries in elementary school-aged children in Tuah Negeri District, Musi Rawas Regency. Methods: This study is an analytic observational study with a cross-sectional design. A sample of 70 people was taken randomly from elementary school students in Tuah Negeri District, Musi Rawas Regency. Determination of nutritional status based on anthropometric measurements (TB/U). DMFT examination was carried out by looking at decaying, filling, and missing teeth, then the severity of dental caries was categorized into low (DMFT 0 - 2.6), moderate (DMFT 2.7 - 4.4), high (DMFT > 4.5). Data were analyzed using SPSS version 20 with Chi-Square Test analysis. Result: The results of the measurement of nutritional status showed that 34 children (48.6%) were stunted. In stunting children, there are 15 children (44.12%) in the low category, 16 children (47.06%)  in the medium category, 3 children (8.82%) in the high category. The results of the bivariate analysis obtained p = 0.000. Conclussion: There is a significant relationship between stunting and the severity of dental caries in children aged 10-12 years in Tuah Negeri District, Musi Rawas Regency. It is necessary to increase efforts to promote health related to stunting and dental health through health education activities by involving the role of parents in choosing food intake and in maintaining children's dental and oral hygiene
Analysis of Socio-Economic Status, Morphology, and Dominant Factors of Personal Hygiene Behavior on the Incidence of Pediculosis Capitis at Orphanages in Palembang City, Indonesia Jhon Riswanda; Chairil Anwar; Mohammad Zulkarnain; Rico Januar Sitorus
Budapest International Research and Critics Institute-Journal (BIRCI-Journal) Vol 5, No 2 (2022): Budapest International Research and Critics Institute May
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v5i2.4795

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Pediculosis capitis affects all races and all social levels, but low socio-economic status is more affected by this disease. The mode of transmission can be direct (hair to hair) or through intermediaries such as hats, pillows, mattresses, combs, and veils. This study aims to analysis of socio-economic status, morphology, and dominant factors of personal hygiene behavior on the incidence of pediculosis capitis at Orphanages in Palembang City, Indonesia. The cross-sectional design is a sample of all orphanages in Palembang City. The results obtained were then analyzed by chi-square, logistics regression statistical test, and correspondence analysis. Morphology of pediculosis capitis female body length is 2461.70µm, male is 2596.90µm. Antenna shape are shorter and wider, abdomen curve is protruding. Crest of the paraterga plate is extends into the intersegmental membrane. Knowledge of respondents is not good and suffers from pediculosis capitis by 43 (74.1%), knowledge of respondents is good 52 (57.8%), attitude of respondents is negative and suffers from pediculosis capitis 27 (87.1%), positive attitude of the respondent suffered from pediculosis capitis 25 (42.4%), the respondent's actions were not good and suffered from pediculosis capitis 34 (75.6%), the respondent's action was good 18 (40%). The results of the logistic regression test: the most dominant factor is the attitude of the respondents (OR: 6.260 95% CI: 1.836-21.34). This research needs to be continued with individual characteristics in improving behavior in preventing pediculosis capitis.