Claim Missing Document
Check
Articles

Found 20 Documents
Search

Differences of Increased Bishop Scores Between Neutrophil Swab Vaginal ≤ 5 and > 5 in 41 Weeks of Pregnancy Induced With Misoprostol Boby Hartanto; Joserizal Serudji; Defrin Defrin
Andalas Obstetrics And Gynecology Journal Vol 5, No 2 (2021)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.2.178-185.2021

Abstract

The incidence of labor induction with various indications was to increase. The key to successful labor induction is a ripe cervix. Research shows that the degree of cervical rippening as assessed by the Bishop score is influenced by the level of neutrophils contained in the cervical stroma which can be detected by performing a vaginal swab. Neutrophils will produce collagenase in the form of matrix metalloproteinase - 8 (MMPs - 8) which will degrade cervical collagen fibers, so that the cervix becomes soft and ripe. Misoprostol is the drug most widely used in labor induction today. Purpose: This study was to determine the difference in Bishop score increase between vaginal swab neutrophils ≤ 5 and > 5 in pregnancy ≥ 41 weeks induced by misoprostol.Keywords: Bishop score, neutrophil, vaginal swab, misoprostol
The Effect of Giving Virgin Coconut Oil (VCO) to Changes in Lauric Acid Levels in Breast Milk Ismul Sadly Putra; Joserizal Serudji
Andalas Obstetrics And Gynecology Journal Vol 5, No 2 (2021)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.2.241-251.2021

Abstract

Breastmilk (ASI) is the best food produced by the breast glands, containing all the nutritional elements needed by infants aged 0-6 months. Apart from nutrients, breast milk also has other non-nutritional components that act as immune factors for babies. Babies who are not exclusively breastfed will be more susceptible to chronic diseases, such as heart disease, hypertension, and diabetes as adults and can suffer from malnutrition and obesity. Dietary intake significantly affects milk production. The mother's diet can affect the composition of her milk through several metabolic pathways, especially the concentration of fatty acids and vitamins that are soluble in fat and water, including vitamins A, C, B6, and B12. Lauric acid contained in breast milk can help your minor fight infection and increase immunity to protect from various diseases. Not only for the baby, but virgin coconut oil is also starting to be commonly used by dieters. Virgin coconut oil contains lauric acid CH3 (CH2) 10COOH 50% and caprylic acid CH3 (CH2) 6COOH 7%. Both of these acids are medium-chain saturated fatty acids that are quickly metabolized and have anti-microbial properties. The benefits of virgin coconut oil (VCO) are that it is beneficial for the health of the body, including being antibacterial, antiviral, anti-fungal, and natural anti-protozoa; helps relieve symptoms and reduces health risks associated with diabetes, helps protect against osteoporosis, helps prevent high blood pressure, helps prevent liver disease, keeps the heart and blood vessels healthy, helps prevent cancer, helps you lose weight, maintain stamina, maintain healthy skin and hair.Keywords: Breastmilk, Lauric Acid, VCO
DIFFERENCES IN PROTEASE ACTIVATED RECEPTOR-1 AND THROMBINE LEVELS IN PREECLAMPSIA AND NORMAL PREGNANCY Gistin Khusnul Khatimah; Joserizal Serudji; Vaulinne Basyir
Andalas Obstetrics And Gynecology Journal Vol 6, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.27-34.2022

Abstract

Introduction: Preeclampsia is a condition caused by alterations in endothelial function during pregnancy. Changes in endothelial function result in an increase in coagulation and microvascular fibrin accumulation, which results in impaired placental perfusion. Thrombin, which converts fibrin to fibrinogen, as well as platelet activity, the fibrinolytic system, and anticoagulants, are all procoagulant circumstances in preeclampsia. Thrombin contributes to the pathogenesis of preeclampsia by increasing the expression of sFlt-1 thereby providing an antiangiogenic response. Protease Activated Receptor-1 (PAR-1) is a mediator of thrombin for coagulation and inflammation in preeclampsia. Inhibition of Protease Activated Receptor-1 expression in trophoblasts can enhance placental angiogenesis and vascular remodeling. Recently, only few studies have assessed the levels of Protease Activated Receptor -7 and thrombin in preeclampsia.Objective: To determine the difference in levels of Protease Activated Receptor-1 and thrombin in preeclampsia and normal pregnancyMethods: This study is observational with a cross-sectional comparative study design. Sampling was conducted from March 2020 to March 2021. A total of 66 patients were investigated, with 33 samples of preeclampsia and 33 samples of normal pregnancy. The independent sample T-test was used for statistical analysis.Results: The mean levels of Protease Activated Receptor-1 in the preeclampsia group were higher at 28.56 ± 7.68 ng/mL while normal pregnancy was 21.67 ± 6.92 ng/mL. The results of statistical tests showed that there was a significant difference in levels of Protease Activated Receptor-1 between the preeclampsia and normal pregnancy groups (p<0.05). The mean thrombin level in the preeclampsia group was higher at 72.23 ± 7.99 ng/mL, while in normal pregnancy it was 63.70 ± 8.92 ng/mL. The difference in thrombin levels between the preeclampsia and normal pregnancy groups was statistically significant (p<0.05).Conclusion: Preeclampsia was associated with greater levels of Protease Activated Receptor-1 and thrombin than normal pregnancy. There was a significant difference in the mean levels of Protease Activated Receptor-1 and thrombin between preeclampsia and normal pregnancy.Keywords: Thrombin, Protease Activated Receptor-1(PAR-1), Preeclampsia
Elevated Serum Reactive Oxygen Species Level Predicts Early Abortion Joserizal Serudji; Nuzulia Irawati; Johanes Cornelius Mose; Hirowati Ali; Yusrawati Yusrawati
Molecular and Cellular Biomedical Sciences Vol 5, No 1 (2021)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v5i1.192

Abstract

Background: Impaired trophoblast invasion is associated with early abortion. The calorie needed for the trophoblast cell (TC) invasion is mainly met by adenosine triphosphate (ATP) produced in the mitochondria. Reactive oxygen species (ROS), byproduct of ATP synthesis, plays an important role in cellular physiology, but a high level of ROS may result in deoxyribonucleic acid (DNA) damage or cell dysfunction, thereby impaired TC invasion leading to early abortion. The study aims to determine elevated serum ROS level to predicts early abortion.Materials and method: This was an observational study with a cross-sectional design. Fifty subjects with gestational age less than 12 weeks, consist of 25 early abortions and 25 normal pregnancies subjects, were included in this study. Clinical examination and diagnosis are carried out in 2 Hospitals and 5 Public Health Centers in Padang. Examination of ROS levels was carried out by enzyme-linked immunosorbent assay (ELISA) in the Biomedical Laboratory, Faculty of Medicine, Universitas Andalas. The Mann-Whitney test was used to analyze the difference of serum ROS levels, with a significance level of 0.05.Results: The subjects of the two study groups were equivalent in terms of age, gestational age, and gravidity (p=0.051, p=0.453, and p=1.000). The median ROS levels were found to be 1.36 (1.02-26.30) ng/mL in the early abortion and 1.20 (0.43-2.75) ng/mL in the normal pregnancy (p=0.003).Conclusion: There is a significant difference between ROS levels in early abortion and normal pregnancy.Keywords: ROS, early abortion, normal pregnancy
EDUKASI IBU HAMIL DALAM UPAYA MENINGKATKAN DERAJAT KESEHATAN MASYARAKAT DI KELURAHAN PAMPANGAN NAN XX KECAMATAN LUBUK BEGALUNG KOTA PADANG Joserizal Serudji; Lisma Evareny; Iria Ningsih Busri; Izmi Fadhillah Nasution; Novy Ratnasari Sinulingga; Rani Ashari; Salma Afriliza; Yusmalia Hidayati; Yolanda Syahdia; Yusrawati Yusrawati; Desmawati Desmawati; Aldina Ayunda Insani; Vaulinne Basyir; Hudila Rifa Karmila
BULETIN ILMIAH NAGARI MEMBANGUN Vol 6 No 1 (2023)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v5i2.413

Abstract

The target of SDGs in 2030 in the 3rd goal is to reduce the Maternal Mortality Rate to below 70 per 100,000 live births, reduce the Neonatal Mortality Rate (AKN) to 12 per 1000 live births and the Infant Mortality Rateto 25 per 1000 live birth. Goal 5 of the SDGs seeks to achieve gender equality, empowering women, including child women. The purpose of this activity is to create a complete understanding in all sectors regarding maternal health services during pregnancy, childbirth, postpartum with preventive and promotive efforts through community assistance efforts on the health and welfare of pregnant women. The method used is providing education to husbands and the community about assisting pregnant women. This activity was carried out in Pampangan Nan XX Village, RW 05 (RT 01 - RT 04), Lubuk Begalung District. The samples in this activity were all husbands, community leaders (TOMA) and religious leaders (TOGA). Based on data collection and interviews, it was found that the community participation was still low in assisting mothers during pregnancy (56%). Implementation is carried out by developing innovations in providing education and health promotion to the community in an effort to improve Community Based Health Business (UKBM). Education is provided in the form of videos and pre-test questions sent via whatsapp group to husbands and the community containing material about efforts to assist pregnant women. The evaluation was carried out by giving post-test questions, the results obtained that all husbands and the community (100%) already had good knowledge about maternal assistance during pregnancy.
DETEKSI DINI STUNTING PADA BAYI DAN BALITA DI WILAYAH KERJA PUSKESMAS PEGAMBIRAN KOTA PADANG Yusrawati Yusrawati; Desmawati Desmawati; Arni Amir; Joserizal Serudji; Vaulinne Basyir; Hudilla Rifa Karmia; Aldina Ayunda Insani; Miranie Safaringga; Lisma Evareny
BULETIN ILMIAH NAGARI MEMBANGUN Vol 5 No 3 (2022)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v5i3.367

Abstract

Nutritional status has a significant influence on the growth and development of children. Poor nutrition during the first 1000 days of life (HPK) can reduce the risk of disease, one of which is stunting, as well as the risk of death, which is around 13% (WHO, 2009). In 2018 the percentages of very short and short toddlers aged 0-59 months were 11.5% and 19.3%, respectively. The magnitude of the risk of stunting for infants and toddlers, it is necessary to hold early detection of stunting as an effort to help increase knowledge that is implemented in monitoring activities for growth and development of infants and toddlers that are more optimal. The activity was carried out on November 18, 2021 with 20 mothers who have babies and toddlers. This group was given counseling, physical examination and early detection of growth and development using the KPSP questionnaire. The results showed that 6.25% of underweight infants and 6.25% of obese infants, 44% of infants and toddlers in the short category, 6% very short, 81% of exclusive breastfeeding, 6% of infants with deviations (smooth motion, socialization and independence) and 6 % of dubious results (rough motion). It is hoped that husbands, families and the community will monitor the growth and development of infants and toddlers to prevent stunting and other growth and development disorders. Health workers should always promote balanced nutrition programs and other stuntin prevention efforts since the preparation for pregnancy (preconception).
Sirenomelia: A Case Report Joserizal Serudji
Journal of Midwifery Vol 7, No 1 (2022): Published on June 2022
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jom.7.1.45-50.2022

Abstract

Sirenomelia is an extremely rare anomaly, an incidence of 1 to 4.2 in 100,000 births, in which a newborn born with legs joined together featuring amermaid-like appearance (head and trunk like humans and tail like fish), and in most cases die shortly after birth. Gastrointestinal and urogenital anomalies and single umbilical artery are clinical outcome of this syndrome. There are two important hypotheses for pathogenesis of mermaidsyndrome: vitelline artery steal hypothesis and defective blastogenesis hypothesisThe cause of the sirenomelia is unknown, but there are some possible factors such as age younger than 20 years and older than 40 years in mother and exposure of fetus to teratogenics. Here, we introduced 39 year old mother’s first neonate with  Sirenomelia syndrome. The mother had gestational diabetes mellitus and neonate was born with single lower limb, ambiguous genitalia, and thumb anomalies, and 4 days after birth, the neonate               dieddue to multiple anomalies and imperforated anus.
Pathophysiology of Preeclamsia Hudila Rifa Karmia; Joserizal Serudji
Journal of Midwifery Vol 7, No 1 (2022): Published on June 2022
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jom.7.1.94-102.2022

Abstract

The uncertainty of the etiology and underlying mechanisms of the pathophysiology of this disease makes causal structuring and primary prevention of preeclampsia impossible, making it difficult to control morbidity and mortality, both maternal and perinatal. From the many theories on preeclampsia, the disease can be classified into Placental preeclampsia, maternal preeclampsia, and Vascular Disorders of Pregnancy (VDP). Increased inflammatory response to placental factors, excessive inflammatory response to placental factors, and primary vascular disorders are the basis of distinction and also the basis of pathophysiology among the three forms of preeclampsia.
Rubella Infection In Pregnancy Joserizal Serudji
Journal of Midwifery Vol 7, No 1 (2022): Published on June 2022
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jom.7.1.16-23.2022

Abstract

Rubella is a systemic viral disease that is mild, non-specific, rarely diagnosed, and easily transmitted. Rubella virus easily crosses the placenta, so infection in pregnancy, especially in the first trimester, has the risk of transmitting to the fetus and potentially causing abortion, fetal death, and congenital rubella syndrome (CRS). CRS includes auditory, sensorineural, cardiac, and ocular abnormalities, and is an irreversible congenital disorder. Rubella can be prevented by the administration of antirubella vaccination.Serology tests are still the most reliable diagnostic test today, although these immune reactions appear later than the appearance of the rash. Analysis of serology test results can provide information on whether you are in acute infection, infected, and are still active, or chronic infection and are currently active or inactive.Management of rubella infection in pregnancy is symptomatic, nothing can be done for CRS in pregnancy. Postpartum CRS management is multidisciplinary and supportive
Body Stalk Anomaly: Antenatal Sonographic Diagnosis Yusrawati yusrawati; Reyhan Julio Azwan; Bobby Indra Utama; Hudilla Rifa Karmia; Muhammad Iqbal; Joserizal serudji
Journal of Midwifery Vol 7, No 1 (2022): Published on June 2022
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jom.7.1.103-108.2022

Abstract

The abstract should summarize the content of the paper. Try to keep the abstract below 200 words. Do not make references nor display equations in the abstract. The journal will be printed from the same-sized copy prepared by you. Your manuscript should be printed on A4 paper (21.0 cm x 29.7 cm). It is imperative that the margins and style described below be adhered to carefully. This will enable us to keep uniformity in the final printed copies of the Journal. Please keep in mind that the manuscript you prepare will be photographed and printed as it is received. Readability of copy is of paramount importance.