Utami, Sulistiyati Bayu
Department Of Nutrition Science, Faculty Of Medicine, Universitas Diponegoro

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Hubungan antara jenis asupan karbohidrat dan lemak dengan kadar small dense low density lipoprotein pada pasien penyakit jantung koroner Sofia, Sefri Noventi; Sugiri, Sugiri; Utami, Sulistiyati Bayu; Nugroho, M. Arif; Murbawani, Etisa Adi
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 7, No 1 (2018)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (347.228 KB) | DOI: 10.14710/jgi.7.1.37-42

Abstract

Background: small dense Low Density Lipoprotein (sdLDL) was the most atherogenic lipoprotein. Its influenced by internal and external factors including food consumption. Indonesian people mostly take a diet of high carbohydrate (CH) and fried food that believed to correlate with higher sdLDL level and predisposed to Coronary Heart Disease (CHD). There were 2 types of CH based on the processing ways, refined and non-refined CH.Objectives: The study’s purpose was to prove the correlation between different types of CH and fat intake with the sdlDL level in CHD patients.Methods: cross sectional in CHD patients hospitalized at Dr Kariadi hospital. The sdLDL and others lipid profile examined. The type and amount of CH and fat intakes per-day were collect from an interview using semi-quantitative food frequency questionnaire (SQFFQ) and food models. Pearson and Spearman test used for bivariate analysis. Confounding factors age, gender, physical activity, diabetes mellitus and smoking were analyzed. Variables with p<0,25 was included in multivariate analysis using linear regression test.Results: There were 30 samples with CHD came with acute coronary syndrome (ACS). Mean of total CH intake per day was 267.75 gram. Mean of percentage of CH from total calories per day was 55.93%. This number was higher than advised which is 30-130 gram or <45% of total calorie per day. Mean of refined and non-refined CH intake was 161.80 and 57.81 gr/day. The total CH mostly from refined CH (76%) rather than non-refined. Mean of fat intake was 68 gr/day (32.76% of total energy per day), and the mean of sdLDL level was 26,54 mg/dl. Correlation between refined CH vs non-refined CH with the sdLDL levels (r=0.328; p=0.077 vs r=-0.184;p=0.331). Correlation between fat intake and sdLDL levels (r=0.44;p=0.15). Multivariate analysis was analyzing refined CH fat intake and age with sdLDL level (r=0,28;p=0,13 vs r=0.45;p=0.01 vs r=-0.15;p=0.44). There is significant correlation between fat intake and sdLDL levels with r=0.45Conclusion: There was a significant correlation between fat intake and sdLDL levels in CHD patients. There is no significant correlation between refined and non-refined carbohydrates with sdLDL levels in CHD patients.
PERBEDAAN PROFIL LIPID PADA PASIEN DENGAN ANGINA PEKTORIS STABIL DAN SINDROMA KORONER AKUT Tsyaning, Wikan Tamara; Uddin, Ilham; Sofia, Sefri Noventi; Utami, Sulistiyati Bayu; Setiawan, I Edward Kurnia
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 7, No 2 (2018): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (344.239 KB) | DOI: 10.14710/dmj.v7i2.21185

Abstract

Latar Belakang Penyakit Jantung Koroner (PJK) merupakan masalah kardiovaskular dengan tingkat mortalitas paling tinggi. Manifestasi yang paling sering dari PJK adalah Angina Pektoris Stabil (APS) dan Sindroma Koroner Akut (SKA). Patofisiologi APS dan SKA memiliki perbedaan di vulnerabilitas plak, dimana vulnerabilitas plak itu sendiri berhubungan dengan kadar profil lipid.Tujuan Mengetahui gambaran dan perbedaan profil lipid pada pasien dengan APS dan SKA.Metode Observasional analitik dengan desain cross sectional. Sampel penelitian ini adalah pasien APS dan SKA yang menjalani terapi di RSUP Dr. Kariadi Semarang dan belum mendapat obat antihiperlipidemia ataupun mendapat obat antihiperlipidemia kurang dari seminggu. Data yang diambil merupakan data sekunder. Analisa data menggunakan uji t tidak berpasangan. Perbedaan dinyatakan bermakna jika p>0.05.Hasil Berdasarkan data yang terkumpul sebanyak 38 subjek, didapatkan perbedaan rerata profil lipid, yaitu kolesterol total, trigliserida, LDL, dan HDL antara subjek APS dan SKA berturut-turut 184.11±41.96 mg/dl dan 192.63±47.38 mg/dl; 120.42±44.04 mg/dl dan 148.05±52.22 mg/dl; 115.68±36.68 mg/dl dan 126.11±44.56mg/dl; 44.42±11.51 mg/dl dan 39.74±13.61 mg/dl. Pada Uji t tidak berpasangan tidak didapatkan perbedaan bermakna antara kedua kelompok pada masing-masing profil lipid dengan nilai p pada kolesterol total, trigliserida, LDL, dan HDL berturut-turut 0.561, 0.086, 0.436, dan 0.162.Kesimpulan Tidak terdapat perbedaan bermakna kadar profil lipid pada pasien APS dan pasien SKA.
HUBUNGAN KADAR LAKTAT TERHADAP LAMA PERAWATAN DI INSTALASI RAWAT INTENSIF PADA PASIEN PASCABEDAH PINTAS ARTERI KORONER Dhika Adhi Pratama; Sulistiyati Bayu Utami; Ariosta Ariosta
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 6, No 4 (2017): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (350.025 KB) | DOI: 10.14710/dmj.v6i4.18380

Abstract

Latar Belakang : Penyakit jantung koroner merupakan salah satu masalah kesehatan utama yang menjadi penyebab nomor satu kematian di dunia setiap tahunnya. Salah satu penatalaksaan yang dapat dilakukan adalah bedah pintas arteri koroner (BPAK). Hiperlaktatemia pascabedah dengan Cardiopulmonary Bypass dikaitkan dengan rendahnya perfusi jaringan, yang akan memperburuk luaran pascabedah. maka dibutuhkan suatu penanda untuk memprediksi luaran pascabedah.Tujuan : Mengetahui adanya hubungan kadar laktat dengan lama rawat inap di ruang Instalasi Rawat Intensif pada pasien pasca BPAK.Metode : Penelitian ini merupakan penelitian korelasi observasional dengan rancangan Kohort Prospektif. Subjek penelitian sebanyak 55 orang dipilih secara consecutive sampling dari pasien pascabedah pintas arteri koroner di RSUP Dr. Kariadi Semarang. Uji hipotesis menggunakan uji komparatif Mann-Whitney dan Uji Korelasi Spearman.Hasil : Terdapat korelasi yang bermakna antara kadar laktat dan lama rawat  IRIN. (p=0,002). Nilai korelasi spearman (0,400) menunjukkan bahwa terdapat korelasi positif antara variabel. Tidak terdapat perbedaan bermakna lama rawat antara kelompok kadar laktat <4 mmol/L dan ≥4 mmol/L (p=0,612). Rata-rata kadar laktat darah pada pasien pascabedah pintas arteri koroner adalah 4,1 mmol/L.Simpulan : Terdapat hubungan kadar laktat dengan lama rawat di Instalasi Rawat Intensif pada pasien pascabedah pintas arteri koroner. Tidak terdapat perbedaan bermakna lama rawat inap pada pasien pascabedah katup jantung rematik dengan kadar laktat <4 mmol/L dan ≥4 mmol/L.
Ekstraksi lead crt ventrikel kiri yang patah Isyana Miranti; Made Satria Yudha Dewangga; Widyo Mahargo; Sulistiyati Bayu Utami; yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 36, No. 3 Juli - September 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i3.478

Abstract

In recent years, implantation of cardiac resynchronization therapy (CRT) devices has significantly increased. Left ventricular (LV) pacing through the Coronary Sinus (CS) is the standard approach for CRT. Many LV lead placement techniques to get lead stability and optimal threshold, one with wire PCI. We presented a case with LV lead CRT extraction were broken after being fitted with wire PCI with stabilization purpose and to obtain an appropriate threshold, the extraction was done by snaring techniques.