@article{IPI775192, title = "Influence of Mesenchymal Stem Cell Transplantation in Retaining Ganglion Cell of End Stage Glaucoma Patients", journal = "Faculty of Medicine Universitas Indonesia", volume = "Vol 6, No 2 (2018): Vol 6, No. 2 (2018): Agustus", pages = "", year = "2018", url = author = "Widya Artini", abstract = "Mesenchymal stem cells transplantation enhances nerve growth factor synthesis, brain derived nerve factor, glial cell line-derived neurotropic factor, and neurotrophin-3.. We report four end-stage primary open angle glaucoma patients, consisting of three males and one female with a median age of 68 years old, treated at RSCM on September 2017. Visual acuity ranged between 1/300 to 2/60 and intraocular pressure (IOP) between 10-14 mmHg. All patients underwent allogeneic mesenchymal stem cells transplantation derived from umbilical cord by subtenon injection and evaluated the results of the potential evoked retinograph and average thickness of ganglion cell-inner plexiform layer (GC-IPL). Three months later, two patients admitted their vision was improved. with, no significant anatomical structure changes were observed. While two other patients did not report any significant effects.", }