Molekul: Jurnal Ilmiah Kimia
Vol 12, No 2 (2017)

Time-Kill Assay of 4-Hydroxypanduratin A Isolated from Kaempferia Pandurata Against Foodborne Pathogens

Soerya Dewi Marliyana (Universitas Sebelas Maret)
Didin Mujahidin (Unknown)
Yana M Syah (Unknown)
Yaya Rukayadi (Unknown)

Article Info

Publish Date
30 Nov 2017

Abstract

Time–kill assay was performed for 4-hydroxypanduratin A that was isolated from Kaempferia pandurata rizhome against four important foodborne pathogens, namely Bacillus cereus ATCC 21772, Bacillu subtilis ATCC 6633, Staphylococcus aureus ATCC 29737,  and  Proteus mirabilis ATCC 21100. The methods have been investigated in term of Minimum Inhibitory Concentration (MIC) and killing time curve using methods of Clinical and Laboratory Standards Institute (CLSI) guidelines. The results showed that 4-hydroxypanduratin A rapid acting in killing bacteria as follow: B. cereus : 1×MIC for 4 h, P. mirabilis: 4×MIC for 0.5 h, meanwhile  B. subtilis and S. aureus were 1×MIC for 2 h. In conclusion, 4-hydroxypanduratin A showed strong antimicrobial activity against four important foodborne pathogens.

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Journal Info
Molekul: Jurnal Ilmiah Kimia
Website

Abbrev

jm

Publisher

Universitas Jenderal Soedirman

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry

Description

MOLEKUL is a peer-reviewed journal of chemistry published by the Department of Chemistry, Faculty of Mathematics and Natural Sciences, Jenderal Soedirman University, Indonesia. Publishing frequency 2 issues per year, on May and November. This Journal encompasses all branches of chemistry and its ...