Jurnal Natur Indonesia
Vol 10, No 1 (2007)

Studi Sintesis Analog Piokelin III: Sintesis Asam 3-Asetil-2-(2-(2-Hidroksifenil)- 4,5-Dihidrotiazol-4-Il)Tiazolidine-4-Karboksilat

Zamri, Adel (Unknown)

Article Info

Publish Date
04 May 2018

Abstract

The total syntheses of 3-acetyl-2-(2-(2-hydroxyphenyl)-4,5-dihydrothiazole-4-yl) thiazolidine-4-carboxylic acid, a new pyochelin analog is described. The molecule intermediate 4’-(2-hydroxy-phenyl)-2,3,4,5,2’,5,-hexahydro- [2,2’]bithiazolil-4-carboxylic acid was obtained in 4 steps reaction from 2-hydroxybenzonitrile in good yields. The Nacetylation of molecule intermediate was carried out by acetic anhydride to produce pyochelin analog in moderate yields.

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Journal Info
Jurnal Natur Indonesia
Website

Abbrev

JN

Publisher

Universitas Riau

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry

Description

JURNAL NATUR INDONESIA terbit sejak tahun 1998, merupakan jurnal ilmu sains yang menyajikan artikel mengenai hasil penelitian, pemikiran dan pandangan dari peneliti dan pakar dalam bidang biosains (ilmu dasar), meliputi biologi, fisika, kimia dan matematika. Jurnal Natur Indonesia melibatkan mitra ...