Acta Chimica Asiana
Vol. 2 No. 1 (2019)

Synthesis Of Mesoporiic Silica From Rice Husk Ash For Pinostrobin Based Drug Delivery

Rifia Wulandari (Department of Chemistry, Faculty of Mathematics and Natural Science, University of Mataram)
Saprini Hamdiani (Department of Chemistry, Faculty of Mathematics and Natural Science, University of Mataram.)
Nurul Ismillayli (Department of Chemistry, Faculty of Mathematics and Natural Science, University of Mataram.)



Article Info

Publish Date
15 Feb 2019

Abstract

A study has been conducted on the synthesis of mesoporous silica as introductory material pinostrobin anticancer compounds. The aim of this study was to synthesis paramagnetic mesoporous silica from rice husk ash waste; knowing the characteristics of silica gel and mesoporous silica from rice husk and the value of adsorption capacity (Q). Based on the results of the study, it was found that mesoporous silica can be synthesized from the rice husk ash waste. Characterization using FTIR produces silanol (Si-OH), and siloxan (Si-O-Si). The use of 30% w/w tartaric acid as a template doesn’t change the functional groups of silica. The optimum conditions of adsorption of pinostrobin compounds by mesoporous silica at the adsorption capacity of 7.049 mg/g. In simulated intestinal fluids (pH 7.4),pinostrobin is released slowly at every hour, then slightly increases at the 10th hour and continues to increase again slowly so that the pinostrobin compound is completely released at 12 hours.

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Journal Info

Abbrev

ACA

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Materials Science & Nanotechnology

Description

Acta Chimica Asiana (online ISSN 2550-0503, print ISSN 2550-049x) is a peer-reviewed, open access journal that publishes high-quality original research articles as well as review articles and short communication in all areas of Chemistry, including Chemical Education and Chemical Engineering. The ...