Medical Laboratory Technology Journal
Vol 6, No 1 (2020): June

Renal Function Evaluation in Secondary Amyloidosis According to Location of Deposition

Serhat Özçelik (University of Health Sciences Kartal Dr. Lütfi Kırdar Training and Research Hospital, Department of Endocrinology and Metabolism, İstanbul, Turkey)
Gülizar Manga Şahin (University of Health Sciences Sultan Abdülhamid Han Training and Research Hospital, Department of Nephrology ,Istanbul, Turkey)

Article Info

Publish Date
22 May 2020


It aimed to evaluate the renal functions according to the accumulation site of amyloid in patients diagnosed with secondary amyloidosis by renal biopsy. Fifty patients diagnosed with secondary amyloidosis, who referred to the nephrotic syndrome outpatient clinic included in the study. According to the findings of renal biopsy, only-glomerular amyloid deposition (group- 1) detected in 9 patients and glomerular+ tubulointerstitial deposition (group- 2) identified in 41 patients. Serum creatinine, creatinine clearance, and total proteinuria levels compared between groups at the time of presentation and on 3rd, 6th, 12th, and 24th months. Initial and subsequent serum creatinine, creatinine clearance, and total proteinuria levels not found to be significantly different between groups (p>0,05 for all). Among subjects with only-glomerular deposition, statistically significant descents in total proteinuria, when compared to initial levels, were observed from the beginning of the 6th month to the end of the 24th month (p

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Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health


The aim of this journal publication is to disseminate the conceptual thoughts or ideas and research results that have been achieved in the area of medical laboratory sciences. This Journal particularly focuses on the main problems in the development of the sciences of medical laboratory areas. It ...