JURNAL ILMIAH KESEHATAN SANDI HUSADA
Vol 8 No 2 (2019): Jurnal Ilmiah Kesehatan Sandi Husada

Pengaruh Asupan Asam Folat Terhadap Kejadian Preeklamsi

Lazulfa Inda Lestari (Unknown)



Article Info

Publish Date
30 Dec 2019

Abstract

Preeclampsia is one of the three highest factors in the death of a pregnant woman. WHO data states that 585,000 women die annually during pregnancy or childbirth and more than half (58.1%) are caused by preeclampsia and eclampsia. There is a triad of symptoms of preeclampsia namely, proteinuria, edema, and hypertension. Although the cause of preeclampsia is still unknown, the initial stage of pathogenesis begins with an abnormal placenta due to nutrition. One nutrient that plays a role is folic acid. In pregnant women who experience preeclampsia, their folic acid levels are very low and their homocysteine ​​is very high. The recommended intake of folic acid for pregnant and lactating women, is 0.4 mg / day due to folic acid deficiency resulting in preeclampsia suffering from maternal hypertension, proteinuria, kidney damage, and increased fetal death. Folic acid can be found in fresh fruit, yeast, liver, green leaves, and mushrooms. Folic acid acts as a metal donor in the remetilation reaction of homocysteine ​​metabolism. If folic acid deficiency occurs, there will be no change in homocysteine ​​to methionine which ends in hyperhomocysteinemia

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Journal Info

Abbrev

JIKSH

Publisher

Subject

Health Professions Nursing Public Health

Description

Jurnal Ilmiah Kesehatan Sandi Husada bertujuan untuk memberikan akses publikasi hasil penelitian maupun studi kasus para dosen dan mahasiswa dalam mempublikasikan artikelnya. Jurnal Ilmiah Kesehatan Sandi Husada adalah akses terbuka, jurnal peer-review yang mencakup semua aspek dari ilmu Kesehatan ...