International Journal of Nasopharyngeal Carcinoma
Vol. 1 No. 03 (2019): International Journal of Nasopharyngeal Carcinoma

ACTIVITY OF SUPEROXIDE DISMUTASE ENZYME IN EARLY AND ADVANCED STAGES OF NASOPHARYNGEAL CARCINOMA

Gunterus Evans (Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia)
Abdul Kadir (Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia)
Riskiana Djamin (Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia)
Abdul Qadar Punagi (Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia)
Sutji P. Rahardjo (Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia)
Mochammad Hatta (Department of Molecular Biology and Immunology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia)



Article Info

Publish Date
17 Dec 2019

Abstract

Introduction:Nasopharyngeal cancer (NPC) ranks - fourth among all cancers in Indonesia. Objective:This study aimed to determine the levels of SOD in patients with NPC. Material and methods : This was a cross sectional study of analytic observational, using consecutive sampling, with 45 patients with NPC and 15 controls. Results: Average of SOD enzyme levels were higher in the NPC patient group (± 1877.87224 1137.119495) compared with the control group (± 441.42120 320.355669) (p <0.05). SOD enzyme levels were higher in advanced stage ± 2060.67363 1179.147923 compared with early stage ± 1338.86685 680.958439 (p <0.05). Conclusion: The level of SOD enzyme in patients with nasopharyngeal cancer is higher than in the control group, and the level is higher in the advanced stage group than in the early stage group.

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Journal Info

Abbrev

IJNPC

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

The International Journal of Nasopharyngeal Carcinoma (IJNPC) is an open access journal that publishes research findings from disciplines related to nasopharyngeal carcinoma. This journal was published by the Center of Excellence Nasopharyngeal Carcinoma Universitas Sumatera Utara, collaborated with ...